Dataset Overview
RBP
HNRNPL
Knock-Method
shRNA
RBP Family
RRM_5
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR155BMF
Platform
HiSeq
Pubmed ID
32252787
HNRNPL - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of HNRNPL
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
15.89
6.24
-1.15353
2.53790E-12
4.16830E-11
A2M
2149.68
2855.47
0.51340
6.77750E-11
8.81469E-10
AAAS
25.65
31.23
0.22821
0.00576
0.01396
AAK1
2.42
1.86
-0.38328
0.01228
0.02696
AAMDC
23.01
16.22
-0.42117
0.00588
0.01421
AAR2
19.98
15.19
-0.38453
3.01483E-06
1.63720E-05
AARS
64.38
51.42
-0.27467
0.00108
0.00322
AARS2
4.86
6.05
0.28821
0.00333
0.00864
AARSD1
13.3
15.8
0.30886
0.02620
0.05186
AASDH
5.26
4.12
-0.33863
0.00199
0.00551
Showing 1 to 10 of 7,443 entries
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Function Analysis of Target Genes of HNRNPL
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101576820_101576968_101572774_101572901_101577064_101577241
0.00100
0.323
DataSet_01_327
View details
ABCC2
101576820_101576911_101572774_101572901_101577064_101577156
0.00272
0.3
DataSet_01_327
View details
ABHD14A-ACY1
52019222_52019287_52018062_52018174_52019376_52019481
0.00654
-0.06
DataSet_01_327
View details
ABI1
27044583_27044670_27040526_27040712_27047990_27048167
0.00010
-0.228
DataSet_01_327
View details
AC007246.3
39811744_39811950_39785122_39785187_39826505_39826679
0.00169
-0.377
DataSet_01_327
View details
AC010642.1
58823393_58823427_58817453_58817582_58823531_58823828
0.00452
0.244
DataSet_01_327
View details
AC018865.8
130792262_130792404_130791882_130791950_130792706_130792835
0.00115
0.387
DataSet_01_327
View details
ACN9
96765699_96765779_96747034_96747209_96810323_96810799
0.00897
-0.032
DataSet_01_327
View details
ACSL4
108976052_108976210_108938879_108939425_108976367_108976554
0.00483
0.08
DataSet_01_327
View details
ACSM2B
20556033_20556144_20554456_20554584_20556478_20556580
0.00290
-0.047
DataSet_01_327
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Showing 1 to 10 of 541 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52570799_52570936_52575765_52576039_52569653_52569802
0.00838
0.173
DataSet_01_327
View details
ABCA1
107579506_107579585_107579612_107579685_107578423_107578626
0.00634
-0.201
DataSet_01_327
View details
ABCC2
101569890_101569975_101572774_101572901_101567839_101567986
0.00000
0.223
DataSet_01_327
View details
ABHD14A-ACY1
52018062_52018174_52019222_52019287_52012274_52012390
0.00647
0.052
DataSet_01_327
View details
ABI1
27044583_27044670_27047990_27048164_27040526_27040712
0.00187
0.182
DataSet_01_327
View details
ABI1
27044583_27044670_27047990_27048167_27040526_27040712
0.00647
0.132
DataSet_01_327
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ABI2
204244930_204245107_204255768_204255866_204231599_204231767
0.00008
0.334
DataSet_01_327
View details
ACP1
275139_275201_276979_277085_272191_272305
0.00861
-0.157
DataSet_01_327
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ACSL4
108926364_108926601_108939372_108939425_108925947_108926125
0.00276
-0.068
DataSet_01_327
View details
ADK
75960521_75960596_75984295_75984349_75936443_75936644
0.00024
-0.246
DataSet_01_327
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Showing 1 to 10 of 213 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADM
76252384_76252550_76252384_76252482_76253181_76253260
0.00508
0.211
DataSet_01_327
View details
ACADM
76252384_76252601_76252384_76252482_76253181_76253260
0.00476
0.226
DataSet_01_327
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ACADM
76252384_76252539_76252384_76252482_76253181_76253260
0.00788
0.224
DataSet_01_327
View details
ADARB1
46641932_46643492_46641932_46642022_46645461_46646475
0.00087
-0.595
DataSet_01_327
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AKR1C2
5041391_5042858_5042741_5042858_5040816_5040939
0.00001
-0.171
DataSet_01_327
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ATP5J2-PTCD1
99063733_99063787_99063751_99063787_99057708_99057816
0.00352
-0.076
DataSet_01_327
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BPTF
65941524_65942441_65941524_65942012_65943841_65943924
0.00586
-0.135
DataSet_01_327
View details
CBY1
39067080_39067297_39067080_39067193_39069163_39069418
0.00306
0.142
DataSet_01_327
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CHRD
184104838_184104908_184104838_184104895_184105718_184105821
0.00126
-0.022
DataSet_01_327
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CHRD
184103833_184104543_184103833_184103947_184104632_184104726
0.00338
-0.26
DataSet_01_327
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Showing 1 to 10 of 61 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSL4
108926364_108926604_108926364_108926601_108939372_108939425
0.00002
0.288
DataSet_01_327
View details
ACTG1
79478928_79479168_79478928_79479141_79479257_79479386
0.00002
-0.034
DataSet_01_327
View details
ADIPOR1
202914110_202914323_202914110_202914297_202915566_202915738
0.00382
0.036
DataSet_01_327
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AHSG
186337645_186337729_186337663_186337729_186336285_186336426
0.00040
-0.029
DataSet_01_327
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ANKRD11
89383340_89383486_89383340_89383483_89427902_89428085
0.00789
-0.175
DataSet_01_327
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APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00005
-0.015
DataSet_01_327
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APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00316
-0.025
DataSet_01_327
View details
APRT
88875876_88876248_88875876_88876114_88876477_88876556
0.00050
-0.123
DataSet_01_327
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AQP7
33384947_33385288_33384947_33385229_33385646_33385864
0.00323
-0.434
DataSet_01_327
View details
ASGR1
7081812_7081930_7081812_7081907_7082508_7082883
0.00116
0.023
DataSet_01_327
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AKT1
105237081_105238789_105237081_105237184_105238701_105238789
0.00855
-0.024
DataSet_01_327
View details
AP1G2
24031712_24032847_24031712_24031802_24032588_24032847
0.00009
0.175
DataSet_01_327
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ARHGEF40
21555159_21555622_21555159_21555264_21555478_21555622
0.00706
0.29
DataSet_01_327
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ASPSCR1
79974675_79974989_79974675_79974745_79974816_79974989
0.00040
0.063
DataSet_01_327
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ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00008
0.07
DataSet_01_327
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B2M
45007620_45008554_45007620_45007899_45008526_45008554
0.00963
0.009
DataSet_01_327
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C2orf49
105959304_105959680_105959304_105959431_105959557_105959680
0.00326
-0.167
DataSet_01_327
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CARS
3023199_3023830_3023199_3023283_3023770_3023830
0.00479
0.161
DataSet_01_327
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CCNG1
162864576_162864810_162864576_162864670_162864770_162864810
0.00005
-0.185
DataSet_01_327
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CHRD
184103833_184104726_184103833_184103947_184104632_184104726
0.00347
-0.296
DataSet_01_327
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
113672569
A
G
0.00742
.
FALSE
AluJb
SINE,Alu
chr1
27202959
T
C
0.00094
.
FALSE
AluSq2
SINE,Alu
chr1
145290818
C
G
0.00931
NBPF20
+
FALSE
chr1
31905889
A
G
0.00483
SERINC2
+
FALSE
chr1
145282600
A
C
0.00391
NBPF20,NOTCH2NL
+
FALSE
MER126
SINE,Alu
chr1
26755209
A
G
0.00745
LIN28A
+
FALSE
AluSx1
SINE,Alu
chr1
20978457
T
C
0.00036
PINK1-AS,DDOST
-
TRUE
AluY
SINE,Alu
chr1
28835937
A
G
0.00025
SNHG3,RCC1
+
TRUE
AluSx4
SINE,Alu
chr1
36535560
A
G
0.00059
.
FALSE
AluSx1
SINE,Alu
chr1
90048248
C
T
3.54659E-05
LRRC8B
+
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression