Dataset Overview
RBP
U2AF2
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR622MCX
Platform
HiSeq
Pubmed ID
32252787
U2AF2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of U2AF2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
11.1
1.77
-2.33320
3.79051E-40
1.27055E-38
A1CF
47.59
35.25
0.37792
0.00046
0.00094
A2M
3527.82
2180.74
-1.03400
1.99937E-23
2.45124E-22
A4GALT
0.64
1.11
0.94128
0.00149
0.00281
AAAS
18.34
12.55
-0.58552
5.42702E-06
1.41630E-05
AACS
10.62
7.81
-0.31730
0.00645
0.01099
AAGAB
10.36
12.34
0.67866
3.37939E-07
1.01770E-06
AAK1
4.32
11.95
1.69335
9.57961E-38
2.87960E-36
AARS2
4.14
2.29
-0.73618
6.97378E-06
1.79248E-05
AARSD1
11.63
6.33
-0.69302
0.00299
0.00538
Showing 1 to 10 of 9,083 entries
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Function Analysis of Target Genes of U2AF2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52622648_52622741_52619601_52619745_52645340_52645387
0.00002
0.059
DataSet_01_331
View details
A2M
9265105_9265285_9264754_9264807_9265955_9266139
0.00000
0.658
DataSet_01_331
View details
AAGAB
67495885_67495935_67494044_67495236_67496381_67496486
0.00000
-0.807
DataSet_01_331
View details
ABCA5
67244402_67244458_67243091_67243785_67246045_67246125
0.00512
-0.613
DataSet_01_331
View details
ABCC2
101581647_101581836_101578845_101579026_101590063_101590190
0.00000
0.113
DataSet_01_331
View details
ABCC2
101581628_101581682_101578845_101579026_101590063_101590190
0.00000
0.112
DataSet_01_331
View details
ABCC2
101581628_101581686_101578845_101579026_101590063_101590190
0.00013
0.053
DataSet_01_331
View details
ABCC2
101581647_101581686_101578845_101579026_101590063_101590190
0.00037
0.019
DataSet_01_331
View details
ABLIM1
116227939_116227975_116225456_116225586_116232735_116232891
0.00837
-0.511
DataSet_01_331
View details
ABLIM3
148622053_148622113_148619321_148619451_148624443_148624578
0.00107
0.317
DataSet_01_331
View details
Showing 1 to 10 of 1,132 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52601621_52601752_52603747_52603882_52595833_52596072
0.00191
-0.167
DataSet_01_331
View details
A1CF
52603747_52603882_52619601_52619745_52601621_52601752
0.00802
0.149
DataSet_01_331
View details
ABCC2
101579193_101579299_101581647_101581836_101578845_101579026
0.00000
-0.736
DataSet_01_331
View details
ABCC2
101579184_101579299_101581647_101581836_101578845_101579026
0.00000
-0.609
DataSet_01_331
View details
ABCC2
101579184_101579299_101581628_101581682_101578845_101579026
0.00000
-0.577
DataSet_01_331
View details
ABCC2
101579184_101579299_101581628_101581686_101578845_101579026
0.00010
-0.41
DataSet_01_331
View details
ABCF1
30548182_30548296_30550170_30550284_30547707_30547782
0.00000
0.193
DataSet_01_331
View details
ABCF1
30546246_30546354_30547707_30547782_30546124_30546162
0.00009
-0.072
DataSet_01_331
View details
AC093642.5
243061115_243061208_243072805_243072963_243056789_243056892
0.00385
-0.097
DataSet_01_331
View details
ACAA1
38169276_38169357_38170780_38170879_38168000_38168191
0.00638
0.117
DataSet_01_331
View details
Showing 1 to 10 of 573 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCA5
67270083_67270269_67270099_67270269_67267302_67267430
0.00819
-0.256
DataSet_01_331
View details
ADRBK1
67048563_67048655_67048563_67048648_67048929_67049029
0.00700
-0.103
DataSet_01_331
View details
AHSG
186334975_186335164_186334975_186335139_186336079_186336177
0.00001
-0.091
DataSet_01_331
View details
AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00000
-0.074
DataSet_01_331
View details
AKR1C2
5041391_5042858_5042741_5042858_5040816_5040939
0.00000
-0.232
DataSet_01_331
View details
C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00173
-0.056
DataSet_01_331
View details
CASP8
202141549_202141827_202141549_202141691_202149538_202150040
0.00204
-0.115
DataSet_01_331
View details
CLASRP
45560993_45561156_45560993_45561140_45562525_45562622
0.00851
-0.136
DataSet_01_331
View details
CNOT1
58590750_58590897_58590765_58590897_58589687_58589812
0.00466
-0.129
DataSet_01_331
View details
CPNE1
34220084_34220307_34220232_34220307_34219866_34219947
0.00753
-0.149
DataSet_01_331
View details
Showing 1 to 10 of 59 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9265105_9265151_9265105_9265132_9265230_9265282
0.00000
-0.5
DataSet_01_331
View details
ABCC2
101605380_101605539_101605439_101605539_101604078_101604222
0.00303
-0.096
DataSet_01_331
View details
ADH5
99996064_99996272_99996064_99996200_99997442_99997703
0.00001
0.033
DataSet_01_331
View details
AFMID
76200736_76200934_76200908_76200934_76198783_76198832
0.00000
-0.362
DataSet_01_331
View details
AHSG
186338374_186339107_186338883_186339107_186336285_186336426
0.00817
0.023
DataSet_01_331
View details
ALDOC
26901511_26901616_26901511_26901595_26901713_26901874
0.00177
0.055
DataSet_01_331
View details
AP1G2
24034329_24034551_24034329_24034408_24034814_24034910
0.00000
0.274
DataSet_01_331
View details
AP1G2
24031170_24031387_24031170_24031275_24031496_24031624
0.00018
0.315
DataSet_01_331
View details
AP1G2
24031170_24031394_24031170_24031275_24031496_24031624
0.00179
0.095
DataSet_01_331
View details
AP3D1
2123828_2123891_2123828_2123878_2127150_2127200
0.00000
0.478
DataSet_01_331
View details
Showing 1 to 10 of 233 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9220307_9220820_9220307_9220435_9220778_9220820
0.00037
0.01
DataSet_01_331
View details
ABCD4
74759450_74759951_74759450_74759572_74759856_74759951
0.00739
0.224
DataSet_01_331
View details
ACAA1
38167316_38168191_38167316_38167372_38167652_38168191
0.00002
0.059
DataSet_01_331
View details
ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00002
0.038
DataSet_01_331
View details
ACTR1B
98274889_98275466_98274889_98275106_98275341_98275466
0.00149
0.122
DataSet_01_331
View details
AFMID
76201576_76201819_76201576_76201599_76201683_76201819
0.00000
0.671
DataSet_01_331
View details
AFMID
76200736_76200934_76200736_76200822_76200908_76200934
0.00000
0.728
DataSet_01_331
View details
AKAP8L
15509440_15510221_15509440_15509577_15510112_15510221
0.00764
0.245
DataSet_01_331
View details
AKR1C2
5041391_5042858_5041391_5041469_5042741_5042858
0.00367
0.054
DataSet_01_331
View details
ANAPC5
121764898_121766300_121764898_121765034_121766118_121766300
0.00979
0.069
DataSet_01_331
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Differential Variants in RNA (DVRs)
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Search:
Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
28661656
A
G
0.00319
MED18
+
TRUE
AluSg
SINE,Alu
chr1
118502684
G
A
0.00682
WDR3,SPAG17
+,-
FALSE
chr1
155853061
A
G
0.00146
SYT11
+
TRUE
AluJb
SINE,Alu
chr1
41088377
C
T
8.47840E-10
RIMS3
-
FALSE
chr1
93828523
T
A
0.00155
.
FALSE
chr1
154179193
A
T
0.00122
C1orf43
-
FALSE
chr1
31905886
C
A
0.00273
SERINC2
+
FALSE
chr1
204521616
A
G
4.81420E-06
MDM4
+
TRUE
AluSg
SINE,Alu
chr1
145512078
A
G
0.00907
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
93307479
C
A
0.00085
FAM69A,RPL5
+,-
FALSE
Showing 1 to 10 of 254 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression