Dataset Overview
RBPU2AF2
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR622MCX
PlatformHiSeq
Pubmed ID32252787

U2AF2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of U2AF2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of U2AF2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr128661656AG0.00319MED18+TRUEAluSgSINE,Alu
chr1269237013AG0.00659MDM2+TRUE
chr347386059TC9.15846E-06KLHL18+FALSE
chr1118502684GA0.00682WDR3,SPAG17+,-FALSE
chr6150046603TC0.00730NUP43-TRUEAluSq2SINE,Alu
chr1155853061AG0.00146SYT11+TRUEAluJbSINE,Alu
chr4165998654TC0.00953TMEM192-TRUEAluSgSINE,Alu
chr141088377CT8.47840E-10RIMS3-FALSE
chr193828523TA0.00155.FALSE
chr1154179193AT0.00122C1orf43-FALSE
chr11768386TC0.00208PDDC1-TRUEAluScSINE,Alu
chr131905886CA0.00273SERINC2+FALSE
chr4190883001CG0.00319FRG1+FALSE
chr1204521616AG4.81420E-06MDM4+TRUEAluSgSINE,Alu
chr1145512078AG0.00907NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1747007752AT0.00029SNF8-FALSE
chr193307479CA0.00085FAM69A,RPL5+,-FALSE
chr128662105AG0.00846MED18+TRUEAluSq2SINE,Alu
chr1475202698AG6.15110E-05FCF1+TRUEAluScSINE,Alu
chr1212967264CG0.00781DDX47+FALSE
chr8143744407TC0.00697JRK-TRUEAluJrSINE,Alu
chr110520588TC0.00341.FALSEAluSc8SINE,Alu
chr131837516GC5.10721E-05ZCCHC17+FALSE
chr146165408TC0.00106IPP-TRUEFRAMSINE,Alu
chr140537943AC0.00115CAP1+FALSE(A)nSINE,Alu
chr39848198GT0.00295ARPC4,ARPC4-TTLL3+FALSE(T)nSINE,Alu
chr286252038TC0.00453POLR1A-TRUEAluSq2SINE,Alu
chr125889571GA0.00344LDLRAP1+FALSE
chr1111991845CA0.00803WDR77,ATP5F1+,-FALSE
chr1154128836AT0.00090TPM3-FALSE
chr16282401TC0.00806ICMT-TRUEAluSzSINE,Alu
chr18413129GA0.00040RERE-FALSE
chr7152345392TC0.00643XRCC2-TRUEAluSx1SINE,Alu
chr12120898998AG0.00081GATC+TRUEAluJrSINE,Alu
chr1225707043TC2.18813E-07ENAH-FALSE
chr76501830GA0.00110KDELR2-FALSE
chr417802956TC0.00351DCAF16-TRUEAluSzSINE,Alu
chr6158613393AT0.00108GTF2H5+FALSE
chr124861704GA0.00345RCAN3+FALSE
chr1145116141GA0.00266NBPF20,SEC22B+FALSE
chr1168523504TC0.00029CPT1A-TRUEAluSqSINE,Alu
chr1175526481CA0.00995UVRAG+FALSE
chr417804872TC0.00096DCAF16-TRUEAluSxSINE,Alu
chr1109419841CT0.00057GPSM2+FALSE
chr1108678732TC0.00396SLC25A24-FALSE
chr128825466AG0.00701PHACTR4+TRUEAluSgSINE,Alu
chr126611197CT0.00814UBXN11-FALSE
chr120826786TA0.00030MUL1-FALSE
chr1182568729CG0.00012RGS16-FALSE
chr313670776TC0.00336FBLN2+FALSE
chr1292537702TA0.00368BTG1-FALSE
chr1253435277GT2.75857E-05EIF4B+FALSE
chr310192709CT0.00082VHL+FALSEAluSx1SINE,Alu
chr132799437CT0.00318MARCKSL1-FALSE
chr110518052TC7.90759E-05.FALSEAluJrSINE,Alu
chr119586455AG0.00296MRTO4+TRUEAluSzSINE,Alu
chr11595540TC0.00830CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr117393260TC0.00094PADI2-FALSE
chr1144912233CT0.00066NBPF20,PDE4DIP+,-FALSE
chr11597020CG0.00021CDK11B,SLC35E2B-FALSE
chr178414329GA0.00785FUBP1-FALSEA-richSINE,Alu
chr314986110TC0.00051FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1206581246TC0.00210SRGAP2+FALSE
chr1155695968AG0.00017DAP3+TRUEAluSpSINE,Alu
chr9131872862CG0.00131CRAT-FALSE
chr1120695749AG0.00130.FALSE
chr537290336TC0.00036.FALSEAluSzSINE,Alu
chr16659505GA0.00196KLHL21-FALSE
chr126755209AG0.00745LIN28A+FALSEAluSx1SINE,Alu
chr110368093CA0.00131KIF1B+FALSE
chr286250101TC0.00038LOC90784-TRUEAluSxSINE,Alu
chr613790931TC0.00948MCUR1-TRUEAluSx1SINE,Alu
chr1212277584GC0.00997DTL+FALSE
chr192862904AG0.00279.FALSEAluJrSINE,Alu
chr7129472356CT0.00279UBE2H-FALSE
chr3185826740TG0.00041ETV5-FALSE
chr11769459TC0.00082PDDC1-TRUEAluSq2SINE,Alu
chr116889633TC0.00217NBPF1-TRUE
chr12124105948CT0.00778EIF2B1-FALSE
chr7115898258AT0.00314TES+FALSE(T)nSINE,Alu
chr2112252464GA2.95640E-06MIR4435-2HG-FALSE
chr116927391TC0.00110NBPF1-FALSE
chr1200827638AG0.00665CAMSAP2+FALSE
chr165692500TC0.00281AK4+FALSE(T)nSINE,Alu
chr133148706AG0.00087SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr136752811CT2.19602E-12THRAP3+FALSE
chr1156565056CT0.00498GPATCH4-FALSE
chr1145827050GC0.00045SLC35C1+FALSE
chr116269737CT0.00816ZBTB17-FALSE
chr1326500AG0.00189.FALSE
chr152306075TC0.00135NRDC-FALSE(TCA)nSINE,Alu
chr11255402CG0.00333CPSF3L-FALSE(GCAGG)nSINE,Alu
chr7128607384GA0.00925TNPO3-FALSE
chr315113733TC0.00228RBSN-TRUEAluSz6SINE,Alu
chr237327702TC8.81739E-07.FALSE
chr624780892AC0.00246GMNN+FALSE
chr110520099TC0.00152.FALSEAluSxSINE,Alu
chr1475202532AG1.20675E-07FCF1+TRUEAluScSINE,Alu
chr349142142GT6.70614E-05QARS-FALSE
chr1220231959TC0.00464RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr124989266AT0.00392SRRM1+FALSE
chr765618870AG0.00097CRCP+TRUEAluSx3SINE,Alu
chr1610625414TC0.00015EMP2-TRUEAluSxSINE,Alu
chr1144931392GA0.00241NBPF20,PDE4DIP+,-FALSE
chr1120163520TC0.00017ZNF697-FALSE
chr3113528892AT8.78648E-05ATP6V1A+FALSEAluSpSINE,Alu
chr561683960AG0.00491.FALSE
chr120809386TG0.00561CAMK2N1-FALSE
chr9131812176CT0.00220MIGA2+FALSE
chr110520684TC0.00125DFFA-TRUEAluSc8SINE,Alu
chr1120612194CG0.00561NOTCH2-FALSE(CCG)nSINE,Alu
chr128836900AG0.00018SNHG3,RCC1+TRUEAluScSINE,Alu
chr11650797AG0.00276CDK11B,CDK11A-FALSE
chr1731258352GA0.00417TMEM98+FALSE
chr1610623666TC1.68352E-07EMP2-TRUEAluSpSINE,Alu
chr116933625AG0.00536NBPF1-FALSEGA-richSINE,Alu
chr2201774185TC0.00921.FALSEAluSzSINE,Alu
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chrX77084001TC1.05736E-07MAGT1-TRUEAluSzSINE,Alu
chr1117530273AG0.00601PTGFRN+FALSE
chr133149414AG0.00722SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr495586224AG0.00053PDLIM5+FALSE
chr228002599TA0.00566MRPL33+FALSE
chr116203171CT3.13656E-06SPEN+FALSE
chr1148558170TC0.00235.FALSEAluJbSINE,Alu
chr116768088GA0.00063NECAP2+FALSE
chr1669151495TA0.00304HAS3+FALSE(T)nSINE,Alu
chrX102613351AG0.00969TCEAL9+FALSEL1ME4aSINE,Alu
chr1173387540GA0.00438RAB6A-FALSE
chr133071043AG4.49838E-05ZBTB8A+TRUEAluSx1SINE,Alu
chr1160965287TC0.00766F11R-TRUEAluScSINE,Alu
chr111982544TC4.37710E-05KIAA2013-FALSE
chr115993699CA0.00420.FALSEAluSx4SINE,Alu
chr16948204TC4.22429E-07CAMTA1+FALSEL2aSINE,Alu
chr261764895CA0.00862XPO1-FALSE(AC)nSINE,Alu
chr2114352238GA8.42668E-06WASH2P+FALSE
chr11650657CG0.00379CDK11B,CDK11A-FALSE
chr552386902AG0.00249ITGA2+FALSE
chr136642328CT0.00971MAP7D1+FALSEGA-richSINE,Alu
chr1144053663AT0.00155.FALSE
chr21636053AG0.00189PXDN-FALSE
chr314986080TC4.44089E-16FGD5-AS1-TRUEFLAM_CSINE,Alu
chr11650832AG0.00241CDK11B,CDK11A-FALSE
chr2201735790GC0.00671PPIL3-FALSE
chr642856170AG0.00141RPL7L1+TRUEAluSzSINE,Alu
chr5149363214AG0.00040SLC26A2+TRUEAluJrSINE,Alu
chr1149913733TC0.00143OTUD7B-TRUEMER96BSINE,Alu
chr47765042CT0.00903AFAP1,AFAP1-AS1+,-FALSE
chr2113334241AG0.00388POLR1B+TRUE
chr2203742126TC0.00451.FALSEAluJbSINE,Alu
chr125554719GA0.00403SYF2-FALSE
chr265496187GA0.00266ACTR2+FALSE
chr791742142CA0.00478CYP51A1-FALSEAluSx3SINE,Alu
chr564964314TC0.00208SGTB-TRUEAluScSINE,Alu
chr145671434GC0.00819ZSWIM5-FALSE
chr1119245854TC0.00078E2F8-FALSE
chr110042988AG3.32241E-06NMNAT1+TRUEAluScSINE,Alu
chr116892274AT0.00371NBPF1-FALSE
chr285773494TC0.00099GGCX-TRUEAluYSINE,Alu
chr344790879TC0.00453KIAA1143-TRUEAluYSINE,Alu
chr288327464CT0.00046KRCC1-FALSE
chr1101442569CA0.00567SLC30A7+FALSE
chr1182360928AC0.00635GLUL-FALSE
chr132637068GT0.00146KPNA6+FALSE
chr123636028TA0.00029HNRNPR-FALSE
chr35258280AG4.07938E-08EDEM1+FALSE
chr189648082GA0.00074GBP4-FALSELTR2BSINE,Alu
chr3124948047CG0.00285ZNF148-FALSE
chr1075008815TC0.00309DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr2242384528GT2.14488E-07FARP2+FALSEAluJrSINE,Alu
chr147184569GC0.00061EFCAB14-FALSE
chr1376378459TC0.00239LMO7+FALSE
chr1150446028GT0.00624RPRD2+FALSE
chrX77083955TC0.00065MAGT1-TRUEAluSzSINE,Alu
chr153291382AG0.00132ZYG11B+TRUEAluJrSINE,Alu
chr110519910TC7.27344E-07.FALSEAluJrSINE,Alu
chr1778294253AG0.00031RNF213+TRUEAluSpSINE,Alu
chr5179020622TC2.11448E-05RUFY1+FALSE
chr1610625049TC1.15092E-05EMP2-TRUEAluSx3SINE,Alu
chr119586501AG0.00119MRTO4+TRUEAluSzSINE,Alu
chr347628810TA0.00934SMARCC1-FALSE
chr1112258252AG0.00224RAP1A+FALSE
chr1256215097AT0.00051DNAJC14-FALSE
chr2203922075AG0.00561NBEAL1+FALSE
chr8145139727CT0.00458GPAA1+FALSE
chr2188330198CA0.00091TFPI-FALSEAluJbSINE,Alu
chr286249930TC6.06022E-05LOC90784-TRUEAluJrSINE,Alu
chr3119545349TC0.00805GSK3B-FALSE
chr189447715TG0.00137KYAT3,RBMXL1-FALSE
chr5180682610TC0.00014CTC-338M12.4+FALSE
chr110520702TC0.00438DFFA-TRUEAluSc8SINE,Alu
chr136068325TC0.00065PSMB2-TRUEAluScSINE,Alu
chr5149823795AT0.00261RPS14-FALSE
chr1760522252GA0.00187METTL2A+FALSE
chr3183529603GA0.00219YEATS2+FALSE
chr237328034TC0.00035.FALSE
chr136067760TC0.00362PSMB2-TRUEAluSzSINE,Alu
chr629911284TC0.00019.FALSE
chr1320247038AG0.00391MPHOSPH8+TRUEAluJbSINE,Alu
chr285772404CA0.00015GGCX-FALSE
chr1296259951GA0.00328SNRPF+FALSE
chr2128952699AG0.00497UGGT1+TRUEAluSpSINE,Alu
chr119542310TC0.00532LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr125894468CG0.00357LDLRAP1+FALSEMIRbSINE,Alu
chr135649803AC0.00659SFPQ-FALSE
chr125717365CG0.00229RHCE-FALSE
chr1148003749TC0.00050NBPF8-TRUEL1MC4SINE,Alu
chr1144852203TG0.00518NBPF20,PDE4DIP+,-FALSE
chr141326886CG0.00085CITED4-FALSE
chr1788840TC0.00415LINC01128+FALSE
chr1168220529AG0.00161.FALSEAluSz6SINE,Alu
chr12133298349AG2.42844E-07PGAM5+TRUEAluSpSINE,Alu
chr112071680AG5.54475E-07MFN2+FALSE
chr5128430757TC0.00338ISOC1+FALSE
chr989626918AG0.00048LOC440173-FALSE
chr1116235179GT0.00187VANGL1+FALSE
chr7128143289AG0.00082.FALSEAluSc8SINE,Alu
chr3185646406AT0.00023TRA2B-FALSE
chr116576836AG0.00885FBXO42-FALSE
chr1148252049AC0.00042NBPF8,NBPF14,NBPF9-FALSE
chr348787011TC0.00040PRKAR2A-TRUEAluSx3SINE,Alu
chr1954627915CT0.00015PRPF31+FALSE
chr1206516261CT0.00228SRGAP2+FALSE
chr812880246AG0.00012KIAA1456+TRUEAluJoSINE,Alu
chr154871874CT1.50809E-06SSBP3-FALSE
chr611577085CT1.34362E-05TMEM170B+FALSE
chr3124688639CA0.00165HEG1-FALSE
chr1174983207TG0.00681MRPS14-FALSE
chr291805816GA2.75786E-10.FALSE
chr6153314040GA0.00041MTRF1L-FALSE
chr2121979980GA0.00525TFCP2L1-FALSEL1MB8SINE,Alu
chr110519936TC0.00607.FALSEAluJrSINE,Alu
chr1154554950GT0.00599ADAR-FALSE
chr146764013GA0.00224LRRC41-FALSE
chr3181430141GC0.00086SOX2-OT,SOX2+FALSE
chr5125961649AG3.29658E-05PHAX+TRUEAluSz6SINE,Alu
chr1225684742TC0.00518ENAH-FALSE
chr275120159CT0.00180HK2+FALSE
chr3150261569TG0.00173SERP1-FALSE
chr1773773311TG0.00474H3F3B-FALSE
chr19330479CT0.00027H6PD+FALSE
chr127182750GC0.00141.FALSE
chr3137787047CT0.00735DZIP1L-FALSE
chr1214524576TC0.00337PTPN14-TRUEAluSgSINE,Alu
chr744839297AT0.00777PPIA+FALSE
chr11337737GC2.51903E-05MRPL20-FALSE
chr138280010CT0.00393MTF1-FALSE
chr4154257511CA0.00093TRIM2+FALSE(A)nSINE,Alu
chr261764916AC0.00189XPO1-FALSE(AC)nSINE,Alu
chr110519200TC0.00059.FALSEAluSx3SINE,Alu
chr150906945CT0.00178FAF1-FALSE
chr261386572CG0.00821C2orf74+FALSEAluSzSINE,Alu
chr110520174TC0.00158.FALSEAluSxSINE,Alu
chr131905886CA0.00226SERINC2+FALSE

Differential Expression Gene Analysis