Dataset Overview
RBP
UPF2
Knock-Method
shRNA
RBP Family
MIF4G
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR318OXM
Platform
HiSeq
Pubmed ID
32252787
UPF2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of UPF2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
8.64
16.38
0.79248
2.07497E-07
1.38524E-06
A1CF
29.82
26.93
-0.37235
0.00204
0.00538
AAAS
30.03
40.77
0.23590
0.04752
0.08381
AACS
14.57
8.52
-0.96315
5.91658E-15
1.32920E-13
AAED1
5.35
4.27
-0.38017
0.01661
0.03380
AAGAB
10.84
18.13
0.63825
2.60498E-07
1.70014E-06
AAK1
3.2
0.9
-1.48999
5.79521E-13
9.73102E-12
AAMDC
20.94
47.14
0.99375
1.95984E-08
1.57115E-07
AAR2
20.83
27.58
0.30649
0.00701
0.01602
AARSD1
15.31
26.75
0.52490
0.00099
0.00283
Showing 1 to 10 of 7,657 entries
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Function Analysis of Target Genes of UPF2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101579193_101579299_101578845_101579026_101590063_101590190
0.00294
0.045
DataSet_01_332
View details
ABCC2
101579184_101579299_101578845_101579026_101590063_101590190
0.00345
0.047
DataSet_01_332
View details
ACOT9
23731251_23731325_23725993_23726061_23739997_23740101
0.00958
0.131
DataSet_01_332
View details
ACSL4
108887273_108887415_108872578_108872808_108902582_108902740
0.00866
-0.502
DataSet_01_332
View details
ACSS3
81646457_81646583_81627127_81627250_81647085_81647185
0.00037
0.064
DataSet_01_332
View details
ACTR3B
152508781_152508818_152498705_152498816_152511634_152511730
0.00315
-0.141
DataSet_01_332
View details
ADNP
49535275_49535318_49520425_49520538_49545187_49545353
0.00963
0.071
DataSet_01_332
View details
AFP
74313330_74313393_74309063_74309161_74315051_74315184
0.00191
-0.472
DataSet_01_332
View details
AFP
74320884_74321007_74319481_74319614_74321347_74321494
0.00190
0.021
DataSet_01_332
View details
AGAP3
150817606_150817832_150817073_150817232_150820880_150820937
0.00237
-0.115
DataSet_01_332
View details
Showing 1 to 10 of 256 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI2
204231599_204231767_204244930_204245107_204193002_204193354
0.00430
-0.152
DataSet_01_332
View details
AC005077.12
75722614_75722719_75722887_75723027_75719748_75721484
0.00826
0.133
DataSet_01_332
View details
ACAD8
134126981_134127151_134128408_134128518_134126441_134126542
0.00802
-0.214
DataSet_01_332
View details
ACIN1
23531624_23531713_23532137_23532283_23531376_23531484
0.00670
-0.107
DataSet_01_332
View details
AMT
49458924_49459005_49459536_49459704_49457643_49457775
0.00314
-0.325
DataSet_01_332
View details
ANKRD10
111536044_111536140_111545374_111545610_111530886_111532459
0.00024
-0.354
DataSet_01_332
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ANKRD17
73956383_73958017_73959795_73959945_73950965_73951163
0.00091
-0.229
DataSet_01_332
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ASGR2
7010318_7010470_7010549_7010636_7005408_7005515
0.00703
0.068
DataSet_01_332
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ASNSD1
190530101_190530177_190530766_190532322_190528626_190528680
0.00045
-0.244
DataSet_01_332
View details
ATF2
175976295_175976382_175979417_175979596_175962171_175962321
0.00323
-0.165
DataSet_01_332
View details
Showing 1 to 10 of 96 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCF2
150915166_150915277_150915220_150915277_150913052_150913115
0.00254
-0.217
DataSet_01_332
View details
ADAM9
38947565_38947791_38947565_38947707_38948777_38948865
0.00978
0.025
DataSet_01_332
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APOM
31624248_31624410_31624248_31624403_31625001_31625075
0.00230
0.036
DataSet_01_332
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00021
0.072
DataSet_01_332
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CTDSP2
58221316_58221373_58221334_58221373_58220778_58220880
0.00788
0.1
DataSet_01_332
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FDPS
155287965_155288168_155287965_155288082_155288455_155288544
0.00293
0.029
DataSet_01_332
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FDPS
155287959_155288123_155287959_155288082_155288455_155288544
0.00437
0.013
DataSet_01_332
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HEXA
72646031_72647965_72647899_72647965_72645408_72645519
0.00626
-0.091
DataSet_01_332
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HNRNPH1
179043869_179044111_179044021_179044111_179043098_179043219
0.00423
0.035
DataSet_01_332
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MRPS21
150266288_150266526_150266288_150266318_150266754_150266869
0.00821
0.026
DataSet_01_332
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Showing 1 to 10 of 25 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ARGLU1
107209852_107209999_107209852_107209964_107211779_107212005
0.00001
0.535
DataSet_01_332
View details
AUP1
74754067_74754279_74754067_74754186_74754374_74754490
0.00418
0.033
DataSet_01_332
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AUP1
74754067_74754248_74754067_74754186_74754374_74754490
0.00267
0.043
DataSet_01_332
View details
BAG6
31608161_31608334_31608161_31608305_31608421_31608469
0.00258
0.252
DataSet_01_332
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C1orf63
25570040_25570715_25570040_25570124_25571640_25571792
0.00214
0.312
DataSet_01_332
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CCNL2
1326145_1328183_1326145_1326245_1328775_1328840
0.00322
0.031
DataSet_01_332
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COPB1
14515755_14515985_14515755_14515866_14520383_14520531
0.00312
-0.533
DataSet_01_332
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CRLF1
18708973_18709147_18708973_18709054_18709241_18709403
0.00097
0.585
DataSet_01_332
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DDB1
61081518_61081682_61081518_61081674_61081779_61081958
0.00141
-0.086
DataSet_01_332
View details
DDX5
62496792_62497000_62496792_62496891_62498127_62498187
0.00922
0.206
DataSet_01_332
View details
Showing 1 to 10 of 40 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00439
0.063
DataSet_01_332
View details
ABCF3
183907175_183907545_183907175_183907231_183907366_183907545
0.00990
-0.2
DataSet_01_332
View details
ACAA1
38167652_38168191_38167652_38167832_38168000_38168191
0.00008
0.136
DataSet_01_332
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00185
0.01
DataSet_01_332
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ACTR1B
98274889_98275466_98274889_98275106_98275341_98275466
0.00025
0.142
DataSet_01_332
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AKR1B1
134132049_134132813_134132049_134132133_134132731_134132813
0.00002
0.113
DataSet_01_332
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ANAPC5
121783641_121784808_121783641_121783834_121784698_121784808
0.00533
0.086
DataSet_01_332
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ANXA4
70035037_70037805_70035037_70035128_70037725_70037805
0.00062
0.06
DataSet_01_332
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APEX1
20923736_20924260_20923736_20923862_20924072_20924260
0.00998
0.039
DataSet_01_332
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ASPSCR1
79974675_79974989_79974675_79974745_79974816_79974989
0.00446
0.054
DataSet_01_332
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
2115914
G
T
0.00970
PRKCZ,FAAP20
+,-
FALSE
chr1
9160900
T
C
0.00542
.
FALSE
AluJb
SINE,Alu
chr1
23408939
T
A
1.04314E-06
KDM1A
+
FALSE
chr1
6282401
T
C
1.82955E-05
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
16890428
T
A
0.00233
NBPF1
-
FALSE
chr1
78483452
C
T
0.00094
DNAJB4
+
FALSE
L1MB7
SINE,Alu
chr1
45120664
C
T
0.00437
TMEM53
-
FALSE
chr1
6282301
T
C
0.00290
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
144931392
G
A
0.00286
NBPF20,PDE4DIP
+,-
FALSE
chr1
144932151
G
T
0.00294
NBPF20,PDE4DIP
+,-
FALSE
Showing 1 to 10 of 349 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression