Dataset Overview
RBPXRN2
Knock-MethodshRNA
RBP FamilyXRN_N
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR717SJA
PlatformHiSeq
Pubmed ID32252787

XRN2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of XRN2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of XRN2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr6150047430TC0.00568NUP43-TRUEAluScSINE,Alu
chr231557839GT0.00145XDH-FALSEAluJrSINE,Alu
chr2181737842CT0.00350SCHLAP1+FALSE
chr110520145TC0.00590.FALSEAluSxSINE,Alu
chr425236017TC0.00291PI4K2B+FALSE
chr11683565GA7.19943E-05NADK-FALSE
chr3129033736TC0.00309H1FX-FALSE
chr72290522CT0.00517NUDT1+FALSE
chr310192825AG0.00042VHL+TRUEAluSx1SINE,Alu
chr4190883001CG0.00297FRG1+FALSE
chr8141461185AG0.00793TRAPPC9-FALSE
chr2242512736GC0.00492BOK+FALSE
chr1047098568CT0.00178LINC00842-FALSE
chr2234203547TC0.00476ATG16L1+FALSE
chr1144828845AT0.00178NBPF20,NBPF9+FALSE
chr1179072966CT0.00107ABL2-FALSEMIRcSINE,Alu
chr286248309TC0.00808LOC90784-FALSE
chr817796338GT4.50000E-10PCM1+FALSE
chr426433556AC3.10862E-15RBPJ+FALSE
chr132385071TA0.00436PTP4A2-FALSE
chr136770607TC0.00171THRAP3+FALSE(T)nSINE,Alu
chr133148740AG0.00210SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1424884880TG0.00491NYNRIN+FALSE
chr135650162CA0.00106SFPQ-FALSE
chr127202963CT0.00106.FALSEAluSq2SINE,Alu
chr9132266644AG0.00081LINC00963+TRUEAluSxSINE,Alu
chr1168220427AG0.00670.FALSEAluSz6SINE,Alu
chr261277463AG0.00826PEX13+TRUEAluSxSINE,Alu
chr194995411CA0.00849F3-FALSEAluSxSINE,Alu
chr3123332546CG0.00964MYLK-AS1,MYLK+,-FALSE
chr232535692AG0.00236.FALSEAluJbSINE,Alu
chr128826085AG0.00212PHACTR4+TRUEAluJbSINE,Alu
chr2200792052GA0.00378C2orf69+FALSE
chr116890130AC0.00753NBPF1-FALSE
chr4190883001CG0.00319FRG1+FALSE
chr132697071CA0.00134EIF3I+FALSEAluSpSINE,Alu
chr116703162AT0.00726MRPL17-FALSE
chr19331101AG0.00026H6PD+FALSEAluSxSINE,Alu
chr1681064534AG0.00480CENPN+TRUEAluSgSINE,Alu
chr3100083460GA0.00041TOMM70-FALSEFAMSINE,Alu
chr346623292TC0.00408TDGF1+FALSEAluSx3SINE,Alu
chr398531342AG0.00607DCBLD2-FALSE
chr1145689843AG4.95254E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr140219280TC0.00169PPIE+FALSE
chr237331750TC0.00067.FALSEAluJbSINE,Alu
chr136522615AG0.00658.FALSEAluScSINE,Alu
chr2201842323TC0.00390FAM126B-TRUEAluJbSINE,Alu
chr3156258230TC0.00176SSR3-TRUEAluYk3SINE,Alu
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr232533707AG0.00395.FALSEAluSpSINE,Alu
chr274090064AT0.00197STAMBP+FALSE
chr11344893AG7.94078E-08.FALSEAluSgSINE,Alu
chr119984107GA0.00963MINOS1-NBL1,NBL1+FALSE
chr7131188652GC0.00684PODXL-FALSEMIR3SINE,Alu
chr1953914417AG0.00013ZNF765+TRUEAluSxSINE,Alu
chr136534086AG0.00157.FALSEFLAM_ASINE,Alu
chr1780899281GA0.00053TBCD+FALSE
chr153289892AG0.00070ZYG11B+TRUEFRAMSINE,Alu
chr642857179CA0.00492RPL7L1+FALSEAluSpSINE,Alu
chr1541573612CA0.00355CHP1+FALSE
chr919376249GT5.55883E-05.FALSE
chr1256510706AG0.00053RPL41+FALSE
chr194335332GT0.00973DNTTIP2-FALSE
chr286850798AG0.00267RNF103-CHMP3,RNF103-FALSE
chr19163328TC0.00150.FALSEAluSpSINE,Alu
chr5125962568AG0.00015PHAX+TRUEAluSzSINE,Alu
chr11650787TC0.00071CDK11B,CDK11A-FALSE
chr110517672TC0.00070.FALSEAluSx1SINE,Alu
chr125889571GA0.00344LDLRAP1+FALSE
chr269685864AC0.00610AAK1-FALSE(CA)nSINE,Alu
chr1109465167TA0.00233GPSM2+FALSE
chr237331119TC0.00122.FALSEAluSx1SINE,Alu
chr174665493GA7.81871E-05FPGT-TNNI3K,FPGT+FALSE
chr1423441380TC0.00102AJUBA-TRUEEutr2SINE,Alu
chr5122165512CA0.00276SNX2+FALSE
chr310192617AG2.94246E-06VHL+TRUEAluSx1SINE,Alu
chr986553587GA0.00556C9orf64-FALSE
chr165720330AC0.00211.FALSE
chr1204524546AG0.00054MDM4+TRUEAluYSINE,Alu
chr1229652587TC0.00732ABCB10-FALSE
chr1109475629AG0.00835GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr111982544TC4.37710E-05KIAA2013-FALSE
chr174929861AG0.00705KIF1C+TRUEAluJbSINE,Alu
chr1204521160AG0.00231MDM4+TRUEAluSpSINE,Alu
chr11595602AG9.14189E-05CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr12161135AG0.00028SKI+FALSE
chr3196771049TC0.00010DLG1-FALSE
chr110520258TC0.00746.FALSEAluSxSINE,Alu
chr1121133770AG0.00295SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr128800380CA0.00186PHACTR4+FALSE
chr1153520954CT0.00910LOC101928034,S100A3+,-FALSE
chr12109039869TC0.00795CORO1C-FALSE
chr1765335316TC0.00296PSMD12-TRUEAluSxSINE,Alu
chr1251324122AG0.00226METTL7A+TRUEAluSq2SINE,Alu
chr261150192CA0.00436REL+FALSEAluSz6SINE,Alu
chr466439707TC0.00148EPHA5-FALSE
chr5130536797AG0.00841LYRM7+TRUEAluSx4SINE,Alu
chr146075661AG0.00071NASP+TRUEAluSx4SINE,Alu
chr1121115958TC0.00860SRGAP2-AS1,SRGAP2D,SRGAP2B,SRGAP2C+,-FALSE
chr153291425AG0.00507ZYG11B+TRUEAluJrSINE,Alu
chr153679610GA0.00073CPT2+FALSEAluSzSINE,Alu
chr1110040310AG2.45230E-05CYB561D1+FALSE
chr1117117182CT0.00270IGSF3-FALSE
chr1179044206AG0.00015FAM20B+TRUEAluSxSINE,Alu
chr147716043AG0.00794STIL-FALSE
chr1109479978GT0.00057CLCC1-FALSE
chr110517525TC0.00775.FALSEAluSx1SINE,Alu
chr629911284TC0.00019.FALSE
chr10102121601AG0.00000SCD+TRUEMLT1LSINE,Alu
chr1144828688CT0.00024NBPF20,NBPF9+FALSE
chr132799510TG0.00048MARCKSL1-FALSE
chr3152555188GT0.00016P2RY1+FALSE
chr1214524566TC0.00040PTPN14-TRUEAluSgSINE,Alu
chr126143726GT0.00560SEPN1+FALSEAluSxSINE,Alu
chr314526625TG0.00414SLC6A6+FALSE
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr42940164TC0.00381NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr1939433142TA0.00215FBXO17-FALSEAluJbSINE,Alu
chr1226259443CA0.00927H3F3AP4,H3F3A+FALSE
chr123240263GA5.22984E-05EPHB2+FALSE
chr2171850175GT0.00054TLK1-FALSE
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr114106404GC0.00156PRDM2+FALSE
chr261764916AC0.00361XPO1-FALSE(AC)nSINE,Alu
chr310005650CT0.00698EMC3-FALSE
chr724731065CT0.00414MPP6+FALSE(TGTATG)nSINE,Alu
chr133149443AG2.90388E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr133147942AG0.00423SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr155317685GA0.00121DHCR24-FALSEMIRbSINE,Alu
chr119566382AG0.00513LOC101927895,EMC1+,-FALSE
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr5134086670CA0.00585CAMLG+FALSE
chr111347150CA0.00380UBIAD1+FALSE
chr187213182AT0.00072SH3GLB1+FALSE
chr1148558170TC0.00235.FALSEAluJbSINE,Alu
chr2161130868AC0.00297RBMS1-FALSE
chr153289892AG0.00505ZYG11B+TRUEFRAMSINE,Alu
chr1453243434TC5.94655E-10GNPNAT1-TRUEAluSx3SINE,Alu
chr928403GT1.21037E-06WASH1-FALSEMIRSINE,Alu
chr76501830GA0.00110KDELR2-FALSE
chr11255401GT0.00216CPSF3L-FALSE(GCAGG)nSINE,Alu
chr1145511991AG0.00044NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr275888160AC0.00368MRPL19+FALSEL1MB4SINE,Alu
chr332496328CA0.00013CMTM7+FALSE
chr121808159GA9.34000E-05NBPF3+FALSE
chr119543356TC0.00256LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr119586532AG0.00769MRTO4+TRUEAluSzSINE,Alu
chr1749042206TC0.00030SPAG9-TRUEAluJbSINE,Alu
chr151822219GA0.00223EPS15-FALSE
chr2176792536GT0.00211LNPK-FALSE
chr125687621AT0.00256TMEM50A+FALSE
chr16704652CT1.57063E-06DNAJC11-FALSE
chr7100031502CT0.00091MEPCE+FALSE
chr115015GC0.00809WASH7P-FALSE
chr1145273302AG0.00656NBPF20,NOTCH2NL+FALSE
chr153712215GT0.00458LRP8-FALSE
chr119585545GA0.00696MRTO4+FALSEAluSc8SINE,Alu
chr13730400TC0.00018CEP104-TRUEAluSx3SINE,Alu
chr1145826918GC0.00829NBPF20,NBPF10,GPR89A+,-FALSE
chr133149508AG0.00871SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr5175811091GA0.00592NOP16-FALSE
chr237331065TC0.00585.FALSEAluSx1SINE,Alu
chr193828523TA0.00155.FALSE
chr636894338AG0.00607C6orf89+FALSEGA-richSINE,Alu
chrX77083982TC0.00086MAGT1-TRUEAluSzSINE,Alu
chr116889502TC0.00178NBPF1-TRUEL1MC4SINE,Alu
chr192862337AG0.00595.FALSEAluSpSINE,Alu
chr2132049924AG0.00338LOC440910+FALSEAluSg4SINE,Alu
chr3101576175TC0.00246NFKBIZ+FALSE
chr119586520AG6.58771E-06MRTO4+TRUEAluSzSINE,Alu
chr3195415462GA0.00140LINC00969,SDHAP2+FALSE
chr287883323AG0.00910.FALSE
chr145975358AG0.00020MMACHC+TRUEAluSg7SINE,Alu
chr120238574CT6.32696E-05OTUD3+FALSE
chr126449340GA0.00711PDIK1L+FALSE
chr1532820819TG0.00718WHAMMP1-FALSE
chr11252687TC0.00459CPSF3L-TRUEAluSpSINE,Alu
chr151873951GA0.00588EPS15-FALSE
chr127992824GA0.00503IFI6-FALSE
chr1542192345TC0.00039EHD4-TRUE
chr116259813AG0.00475SPEN+FALSE
chr1725974348CT0.00160LGALS9+FALSE
chr315113810TC0.00201RBSN-TRUEAluSz6SINE,Alu
chr312613866TC0.00043MKRN2+FALSE
chr1182543666TG0.00124RNASEL-FALSE
chr16282255TC0.00954ICMT-TRUEAluSzSINE,Alu
chr276672504AG2.97414E-06.FALSE7SKSINE,Alu
chr2101622883TA0.00440RPL31+FALSE
chr165693725CT0.00202AK4+FALSE
chr9115447527TC0.00200INIP-TRUEAluJbSINE,Alu
chr1244869241CA0.00213DESI2+FALSE
chr349396751TC0.00000RHOA-FALSE
chr12124146073AG0.00085GTF2H3+FALSEAluSx4SINE,Alu
chr16314822TC0.00300GPR153-FALSE
chr123636278AT0.00442HNRNPR-FALSE
chr1145689491AG0.00694NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr116944809GC0.00072CROCCP2-FALSE
chr110517952CA0.00341.FALSE
chr1918477761AG0.00461PGPEP1+TRUEAluJbSINE,Alu
chr327763674TG0.00617EOMES-FALSE

Differential Expression Gene Analysis