Dataset Overview
RBPRBFOX2
Knock-MethodshRNA
RBP FamilyFox-1_C
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR336DFS
PlatformHiSeq
Pubmed ID32252787

RBFOX2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of RBFOX2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of RBFOX2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr119542463TC0.00060LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr339137793CT0.00363WDR48+FALSE
chr131351513GA0.00265SDC3-FALSE
chr136067677TC0.00462PSMB2-TRUEAluSzSINE,Alu
chr16948076CT0.00221CAMTA1+FALSEL2aSINE,Alu
chr224223142AG0.00524UBXN2A+TRUEAluScSINE,Alu
chr1109605648AG0.00033.FALSEAluYSINE,Alu
chr268402796CT0.00656PNO1+FALSE
chr596366330GC0.00251.FALSE(TG)nSINE,Alu
chr1121133733GA0.00467SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr6109785909TC0.00556MICAL1,ZBTB24-TRUEAluJrSINE,Alu
chr1918477761AG0.00461PGPEP1+TRUEAluJbSINE,Alu
chr145452227GC0.00279EIF2B3-FALSE
chr7100860467CG0.00267PLOD3-FALSE
chr116203171CT3.13656E-06SPEN+FALSE
chr133148196AG0.00756SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr128826114AG0.00264PHACTR4+TRUEAluJbSINE,Alu
chr136067817TC0.00120PSMB2-TRUEAluSzSINE,Alu
chr1143135057GA0.00403LOC102723769-FALSE
chr1249745425AG0.00489DNAJC22+TRUEAluSx3SINE,Alu
chr1145369550AG0.00031NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr2174090636TA0.00043ZAK,MLK7-AS1+,-FALSE
chr1206566048GC0.00125SRGAP2+FALSE
chr1160967833TC0.00717F11R-TRUEAluSpSINE,Alu
chr2239972080TA0.00136HDAC4-FALSE
chr2230876757GC0.00321FBXO36+FALSE
chr1150704483TC0.00028CTSS-TRUEAluJoSINE,Alu
chr228635740TC0.00358FOSL2+FALSE
chr126449882AG0.00783PDIK1L+FALSE
chr2025427885AG0.00455GINS1+TRUEAluSzSINE,Alu
chr110517527TC0.00430.FALSEAluSx1SINE,Alu
chr3170113815GT0.00586SKIL+FALSE
chr1541573612CA0.00355CHP1+FALSE
chr136067749TC0.00735PSMB2-TRUEAluSzSINE,Alu
chr1070502288GA0.00347CCAR1+FALSE
chr5125962086AG0.00231PHAX+TRUEAluSzSINE,Alu
chr340577752AG0.00111ZNF621+TRUEAluSzSINE,Alu
chr1168220535AG0.00665.FALSEAluSz6SINE,Alu
chr1749042386TC4.28426E-05SPAG9-TRUEAluJbSINE,Alu
chr210923581CT0.00593ATP6V1C2,PDIA6+,-FALSE
chr16282361TC0.00634ICMT-TRUEAluSzSINE,Alu
chr1161488401TA0.00622FCGR2A+FALSE
chr4177241194CT6.44832E-08SPCS3+FALSE
chr2218571477AG4.57932E-05PEX26+TRUEAluSzSINE,Alu
chr720178490TC0.00028MACC1,LOC101927668-TRUEAluYSINE,Alu
chr12120898697AG0.00488GATC+TRUEAluYSINE,Alu
chr133149399AG0.00308SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr348632596AG0.00666.FALSE
chr159121036AC0.00467MYSM1-FALSE
chr1246831356GA0.00616CNST+FALSE
chr1552203664AC0.01000TMOD3+FALSE
chr375475670AC0.00506FAM86DP-FALSE
chr154691922TA0.00067SSBP3-FALSE
chr344791536TC4.11776E-05KIAA1143-TRUEAluJrSINE,Alu
chr177557891TC0.00557PIGK-FALSE
chr9137330711TA0.00194RXRA+FALSE(GCTG)nSINE,Alu
chr110521237TC0.00200DFFA-TRUEAluYSINE,Alu
chr274333235CT0.00022TET3+FALSE
chr2170497651CT0.00195.FALSE
chr11650845GA0.00094CDK11B,CDK11A-FALSE
chr187170493TG0.00345SH3GLB1+FALSE
chr18412652AC0.00929RERE-FALSE
chr1051613231TC2.61914E-05TIMM23B,TIMM23+,-FALSE
chr1117532372GT0.00678PTGFRN+FALSE
chr775163757TC0.00448HIP1-FALSEAluSx1SINE,Alu
chr579923430TC0.00817DHFR-TRUEAluJrSINE,Alu
chr3195435168TG0.00111LINC00969+FALSE
chr237330507TC9.86666E-05.FALSEAluSq2SINE,Alu
chr3181430141GC0.00086SOX2-OT,SOX2+FALSE
chr12161135AG0.00028SKI+FALSE
chr3122283289CA0.00072DTX3L,PARP9+,-FALSE
chr1144931392GA0.00172NBPF20,PDE4DIP+,-FALSE
chr642856131AG0.00062RPL7L1+TRUEAluSzSINE,Alu
chr6109001947AG0.00359FOXO3+FALSE(A)nSINE,Alu
chr1117618067CT0.00118TTF2+FALSE
chr631110789TC0.00798.FALSE
chr1766264542AT0.00110ARSG,SLC16A6+,-FALSE
chr4184238324GA0.00870WWC2+FALSE
chr631236900GA0.00167.FALSE
chr1220231963TC0.00343RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr35026731CT0.00824BHLHE40+FALSE
chr1326499AG0.00583.FALSE
chr2174090332AC0.00918ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr11594197CT0.00097CDK11B,SLC35E2B-FALSE
chr9115447532TC9.24886E-06INIP-TRUEAluJbSINE,Alu
chr146075724AG0.00990NASP+TRUEAluSx4SINE,Alu
chr9136209398GA0.00150MED22-FALSE
chr4169911112CA0.00142CBR4-FALSE
chr457326875AG1.03861E-05PAICS+TRUEAluSx1SINE,Alu
chr373115390CT0.00462PPP4R2+FALSE(AT)nSINE,Alu
chr125688276AG0.00015TMEM50A+FALSE
chr1757279323AG0.00159PRR11+TRUEAluSq2SINE,Alu
chr129519595TC0.00208MECR-TRUEAluJbSINE,Alu
chr110521170TC0.00498DFFA-TRUEAluYSINE,Alu
chr133145989AT0.00548SYNC,RBBP4+,-FALSE
chr627327349CG0.00359ZNF204P-FALSE
chr175288079AC0.00085RABEP1+FALSE
chr1453242859TC9.31997E-05GNPNAT1-TRUEAluJrSINE,Alu
chr16585331TC0.00779NOL9-TRUEFAMSINE,Alu
chr775677504CT0.00768MDH2+FALSE
chr3156258283TC0.00071SSR3-TRUEAluYk3SINE,Alu
chr12121118CT0.00234FAAP20-FALSE
chr116889566TC0.00305NBPF1-TRUE
chr146076468AG3.83065E-05NASP+TRUEAluSxSINE,Alu
chr136068295TC0.00057PSMB2-TRUEAluScSINE,Alu
chr1145513016AG0.00069NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr11152601AG0.00075SDF4-FALSE
chr41006333GA0.00117FGFRL1+FALSE(CTG)nSINE,Alu
chr1738512480CT0.00725RARA+FALSE
chr1204521159AG0.00158MDM4+TRUEAluSpSINE,Alu
chr138326728TC0.00399INPP5B-TRUEAluJrSINE,Alu
chr12133298937AG0.00240PGAM5+TRUEAluSgSINE,Alu
chr6153314040GA0.00041MTRF1L-FALSE
chr373115786TC3.88619E-05PPP4R2+FALSE
chr1220231263TC0.00116RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr11650801TC0.00761CDK11B,CDK11A-FALSE
chr1144594308GA0.00577NBPF20+FALSE
chr116921146TC0.00382NBPF1-FALSE
chr1204521625AG0.00808MDM4+TRUEAluSgSINE,Alu
chr1248539888CA0.00088PFKM+FALSE
chr41305799CT0.00271MAEA+FALSE
chr116893691CA0.00170NBPF1-FALSE
chr1145689812AG0.00431NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr11595074TC0.00296CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr544826677GT0.00941.FALSE(T)nSINE,Alu
chr220818286AC0.00714HS1BP3-FALSE
chr128661653AG9.75782E-05MED18+TRUEAluSgSINE,Alu
chr5151041884TA0.00101SPARC-FALSE
chr552389817TA0.00868ITGA2+FALSE
chr2188330198CA0.00091TFPI-FALSEAluJbSINE,Alu
chr119543353TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr352237970CT0.00017ALAS1+FALSE
chr1269237042AG0.00413MDM2+TRUE
chr7128142395AC0.00300METTL2B+FALSE
chr110519946TC0.00401.FALSEAluJrSINE,Alu
chr153289686AG0.00460ZYG11B+TRUEAluSzSINE,Alu
chr358306666AG0.00139.FALSEAluSzSINE,Alu
chr11656557TC0.00061SLC35E2-TRUEAluSzSINE,Alu
chr1110207639TA0.00080GSTM4+FALSE
chr5175934037CA0.00182FAF2+FALSEA-richSINE,Alu
chr265496144AG0.00883ACTR2+FALSE
chr2191829133GA0.00097GLS+FALSE
chr1145511988AG0.00900NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1916661483TC0.00824SLC35E1-TRUEAluSzSINE,Alu
chr135817023GC0.00547ZMYM4+FALSE
chr674133913TC0.00439.FALSEAluYSINE,Alu
chr5149363273AG0.00587SLC26A2+TRUEAluJrSINE,Alu
chr2216225584GT0.00848FN1-FALSE
chr155541174AG0.00038USP24-FALSE
chr1742113064AG0.00014LSM12-FALSE(A)nSINE,Alu
chr1475202412AG5.03546E-10FCF1+TRUEAluScSINE,Alu
chr1119245854TC0.00078E2F8-FALSE
chr299772813AG1.48642E-06LIPT1+TRUEAluSx1SINE,Alu
chr116890176AC0.00753NBPF1-FALSE
chr1574319092AG0.00029PML+TRUEAluSz6SINE,Alu
chr2128952075AG0.00919UGGT1+TRUEAluSx1SINE,Alu
chr110221287AG0.00961UBE4B+FALSE
chr226477130TC0.00501HADHB+FALSE
chr116945570AG0.00131CROCCP2-FALSE
chr1742876808TC0.00147GJC1-TRUEAluSz6SINE,Alu
chr1228881190TG0.00043RHOU+FALSE
chr1566791657GT0.00422RPL4-FALSE
chr120826083GA0.00289MUL1-FALSE
chr3196466874GT0.00226PAK2+FALSE
chr565120054CT0.00625NLN+FALSE
chr138423199AT0.00192SF3A3-FALSEAluJoSINE,Alu
chr19160982TC0.00350.FALSEAluJbSINE,Alu
chr19331255AG0.00992H6PD+TRUEAluSxSINE,Alu
chr340353799GT0.00906EIF1B+FALSE
chr179115905TC0.00113IFI44+FALSE
chr1172411768TC0.00416C1orf105,PIGC+,-FALSE
chr128865500TA0.00509RCC1+FALSE
chr1296661613AG0.00183ELK3+FALSE
chr322424405TA0.00766.FALSE
chr299812429AG0.00504MRPL30+TRUEAluSxSINE,Alu
chr532601672AT0.00563SUB1+FALSE
chr11595603CG0.00017CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr919376252AT0.00367.FALSE
chr699319240TA0.00842.FALSECheshireSINE,Alu
chr261278030AG0.00218PEX13+TRUEAluYSINE,Alu
chr1465400786TG0.00077CHURC1-FNTB,CHURC1+FALSEAluSxSINE,Alu
chr537290435TC8.22232E-07.FALSEAluSzSINE,Alu
chr674303531TC0.00487SLC17A5-TRUEAluJrSINE,Alu
chr12125269489CT0.00817SCARB1-FALSE
chr1145442111CA0.00090NBPF20,NBPF10,TXNIP+FALSE
chr111084103TA0.00118TARDBP+FALSE
chr5180663940AG0.00331RACK1-FALSE
chr1144521099AG0.00196NBPF20+FALSE
chr2170607000TA0.00590PHOSPHO2-KLHL23,KLHL23+FALSE
chr6160211652CG0.00719MRPL18+FALSE
chr116944809GC9.47535E-05CROCCP2-FALSE
chr153289686AG0.00265ZYG11B+TRUEAluSzSINE,Alu
chr3191114309AT1.88175E-05CCDC50+FALSE
chr674303543TC0.00031SLC17A5-TRUEAluJrSINE,Alu
chr1117530188AG0.00199PTGFRN+FALSE
chr1160967817TC0.00478F11R-TRUEAluSpSINE,Alu
chr119543352TC0.00086LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr229023124GT0.00477PPP1CB+FALSE
chr1916661541TC0.00120SLC35E1-TRUEAluSzSINE,Alu
chr812283473CT0.00582FAM86B2-FALSE
chr642061234TC0.00170.FALSEAluSx1SINE,Alu
chr393846961AG0.00454.FALSEAluSq2SINE,Alu
chr1610623705TC0.00011EMP2-TRUEAluSpSINE,Alu
chr841401497AG0.00051LOC102723729,GINS4+,-FALSEAluSq2SINE,Alu
chr1204526710AG0.00082MDM4+TRUEAluSxSINE,Alu
chr133277080CT8.00797E-06YARS-FALSELTR6ASINE,Alu
chr192862804AG0.00043.FALSEAluJrSINE,Alu
chr1155217438AT0.00610FAM189B-FALSE
chr285621889CT0.00366CAPG-FALSE
chr128800380CA0.00186PHACTR4+FALSE
chr116112795AG0.00145FBLIM1+FALSE
chr2206983255TC0.00246.FALSEAluJbSINE,Alu
chr1148928344AG0.00608LOC645166+FALSETAR1SINE,Alu
chr244459528GA0.00100PPM1B+FALSE
chr1158067060TA0.00114KIRREL+FALSE
chr120945264AC0.00605CDA+FALSE
chr63022725TC0.00081HTATSF1P2-TRUEAluSzSINE,Alu
chr350150360AG0.00827RBM5+TRUEAluSxSINE,Alu
chr128661692AG0.00219MED18+TRUEAluSgSINE,Alu
chr3197682718TC0.00163IQCG,RPL35A+,-FALSE
chrX77083846TC0.00668MAGT1-TRUEAluSzSINE,Alu
chr1179042687AG0.00163FAM20B+TRUEAluSx1SINE,Alu
chr2217366919AG0.00709.FALSEAluSz6SINE,Alu
chr2219100706AG0.00874ARPC2+TRUEAluSx1SINE,Alu
chr21637531AG0.00664PXDN-FALSE
chr128826150AG0.00047PHACTR4+TRUEAluJbSINE,Alu
chr323958355CT0.00997NKIRAS1,RPL15+,-FALSE
chr110521126TC0.00560DFFA-TRUEAluYSINE,Alu
chr3172115590AG0.00355FNDC3B+FALSE
chr349571462GT0.00032DAG1+FALSE
chr1145688664AT0.00087NBPF20,NBPF10,RNF115+FALSE
chrX118672561TC2.49155E-08CXorf56-TRUEAluSxSINE,Alu
chr1262928633GA0.00307MON2+FALSE
chr6111588769AG2.24603E-05MFSD4B+TRUEAluYm1SINE,Alu
chr128662186AG8.22643E-05MED18+TRUEAluSq2SINE,Alu
chr128661656AG0.00031MED18+TRUEAluSgSINE,Alu
chr146075604AG0.00155NASP+TRUEAluSx4SINE,Alu
chr16283264TC0.00095ICMT-TRUEAluSx3SINE,Alu
chr275888160AC0.00599MRPL19+FALSEL1MB4SINE,Alu
chr417802783TC6.83941E-07DCAF16-TRUEAluSzSINE,Alu
chr1958375707AG0.00156ZNF587+TRUEAluSgSINE,Alu
chr540828060TC0.00253LOC100506548-FALSE
chr1145511796TG0.00173NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSE(T)nSINE,Alu
chr1788795TG0.00333LINC01128+FALSECharlie19aSINE,Alu
chr127678712AG0.00215SYTL1+TRUEAluSx1SINE,Alu
chr1148556743GA0.00402.FALSE
chr128835934AG0.00069SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1916663345TC0.00304SLC35E1-TRUEAluSgSINE,Alu
chrX123046757AG0.00535XIAP+TRUEAluSzSINE,Alu
chr1100676277AG0.00135DBT-FALSE
chr1788844CG0.00406LINC01128+FALSE
chr136534736AG0.00016.FALSEAluJoSINE,Alu
chr116889864CA0.00094NBPF1-FALSE
chr1161160460TA0.00298ADAMTS4-FALSE(CA)nSINE,Alu
chr2217366901AG0.00143.FALSEAluSz6SINE,Alu
chr110521238TC0.00232DFFA-TRUEAluYSINE,Alu
chr5125961447AG0.00563PHAX+TRUEAluSz6SINE,Alu
chr1160967938TC0.00874F11R-TRUEAluSpSINE,Alu
chr3195963395AG0.00028.FALSE
chr3150262002GT0.00016SERP1-FALSE
chr3196077460GT0.00416.FALSE
chr286251114TC0.00709.FALSEAluSxSINE,Alu
chr136770621GT0.00424THRAP3+FALSE(T)nSINE,Alu
chr150906945CT0.00178FAF1-FALSE
chr121545089CT0.00010ECE1-FALSEAluSx1SINE,Alu

Differential Expression Gene Analysis