Dataset Overview
RBPAKAP8
Knock-MethodshRNA
RBP FamilyAKAP95
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR000YYN
PlatformHiSeq
Pubmed ID32252787

AKAP8 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of AKAP8
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of AKAP8


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr189225976TC0.00586PKN2+FALSE
chr1145513094AG0.00633NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr3196044973CT0.00985TCTEX1D2,TM4SF19-TCTEX1D2-FALSE
chr2172412008CG0.00982CYBRD1+FALSE
chr16683578TC0.00151PHF13+FALSE
chr170717293GA0.00716SRSF11+FALSE
chr2128061053AG0.00184MAP3K2-FALSE
chr117199259GA0.00217LOC440570+FALSE
chr366430372TA0.00300LRIG1-FALSE
chr1150199123GT0.00625ANP32E-FALSE
chr1115259768TC0.00156CSDE1-FALSE
chr2242512138AG9.62871E-05BOK+FALSE
chr1205687213TA0.00950NUCKS1-FALSE
chr1179044110AG0.00176FAM20B+TRUEAluSxSINE,Alu
chr634845648TC0.00790TAF11-FALSE
chr1453242652TC0.00081GNPNAT1-TRUEAluJrSINE,Alu
chr168167217GT0.00036GNG12-FALSE
chr110003320GA0.00168LZIC,NMNAT1+,-FALSE
chr2191067766TC0.00034C2orf88+FALSE
chr936216895TC0.00130GNE-TRUEAluYSINE,Alu
chr1101541172AG6.48917E-05LOC102606465+TRUEMLT1KSINE,Alu
chr543298557CT0.00643HMGCS1-FALSE
chr126755643AG0.00068LIN28A+FALSEAluScSINE,Alu
chr1998582GC0.00073.FALSE
chr314986098TC0.00996FGD5-AS1-TRUEFLAM_CSINE,Alu
chr23592615TC0.00331RNASEH1-TRUEAluSz6SINE,Alu
chr116933637AG0.00062NBPF1-FALSEGA-richSINE,Alu
chr4128756579AG0.00501.FALSEAluSxSINE,Alu
chr116933327CT6.62916E-05NBPF1-FALSE
chr11622754AG0.00221CDK11B,SLC35E2B-FALSEMLT1F2SINE,Alu
chr1145512014AG0.00370NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1756049824TC5.91767E-06VEZF1-TRUE
chr42940364TC0.00329NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr110520180TC0.00959.FALSEAluSxSINE,Alu
chr299812808AG5.12907E-06MRPL30+TRUEAluJbSINE,Alu
chr1160990876CA1.09997E-06F11R-FALSE
chr3109045430GA4.43689E-05DPPA4-FALSE
chr1225683184GT0.00741ENAH-FALSE
chr19198079TC0.00933LINC01002-FALSE
chr1200589813CA0.00034KIF14-FALSE
chr1919791276AG0.00069ZNF101+TRUEAluSq2SINE,Alu
chrX3526658AT0.00152PRKX-FALSE(AC)nSINE,Alu
chr110519973TC0.00745.FALSEAluJrSINE,Alu
chr1229738170TG0.00168TAF5L-FALSE
chr118708789AG0.00237RPL27A+TRUEAluSpSINE,Alu
chr1533064148TC1.59288E-05FMN1-FALSE
chr1118167515CT2.81283E-05FAM46C+FALSE
chr116112795AG0.00145FBLIM1+FALSE
chr1534634033AG0.00939NOP10-FALSE
chr1179830012AC0.00303TOR1AIP2-FALSE
chr42940438TC0.00151NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr2176790393CT0.00282LNPK-FALSEAluSpSINE,Alu
chr116893841CT0.00272NBPF1-FALSE
chr237431563AG0.00993CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr116892274AT0.00119NBPF1-FALSE
chr165692498TC0.00356AK4+FALSE(T)nSINE,Alu
chr1179044181AG0.00083FAM20B+TRUEAluSxSINE,Alu
chr146075664AG0.00842NASP+TRUEAluSx4SINE,Alu
chr41380585AG0.00644UVSSA+TRUEAluJrSINE,Alu
chr154571374AG0.00280TCEANC2+TRUEAluScSINE,Alu
chr119670860AG0.00419CAPZB-FALSE
chr811666384CT0.00029FDFT1+FALSE
chr1236702210AG0.00153LGALS8+FALSE
chr119542631TC0.00176LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr237328034TC8.99638E-05.FALSE
chr3107526182TC7.17610E-07BBX+FALSE
chr16283558AT0.00624ICMT-FALSE
chr120826781CT0.00110MUL1-FALSE
chr237330614TC0.00410.FALSEAluSq2SINE,Alu
chr439552183TC0.00479UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr133149373AG0.00264SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr119543247TC5.35430E-06LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr398620372GA3.94317E-05DCBLD2-FALSE
chr133148706AG0.00050SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr124861704GA0.00345RCAN3+FALSE
chr350296330GA0.00645GNAI2+FALSE
chr5176887511AC0.00662DBN1-FALSE
chr119199221CT0.00392ALDH4A1-FALSE
chr2018468339TC0.00062RBBP9-TRUEAluSz6SINE,Alu
chr570503890AT0.00188.FALSE
chr19160866CA0.00907.FALSE
chr291805938AG0.00000.FALSEMLT1H1SINE,Alu
chr7156763172AG0.00874NOM1+TRUEAluSxSINE,Alu
chr1197073932TC0.00032ASPM-FALSE
chr1101354038TC0.00565EXTL2-TRUEL1MB2SINE,Alu
chr11769889TC0.00211PDDC1-TRUEAluYSINE,Alu
chr243625184TA0.00587THADA-FALSE
chr119542401TC0.00071LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr138158705GA0.00168CDCA8+FALSE
chr237429737AG0.00549CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr121766762CG0.00259NBPF3+FALSE
chr477996987TC0.00240CCNI-FALSE
chr123636277AT0.00295HNRNPR-FALSE
chr1773702478GC8.31704E-05SAP30BP+FALSE
chr1953155674TC1.27993E-05ZNF83-TRUEAluSgSINE,Alu
chr136388202TG0.00707AGO1+FALSE(GCCT)nSINE,Alu
chr145504720GC0.00759ZSWIM5-FALSE
chr794060363TG2.98576E-06COL1A2+FALSE
chr144401225TC0.00802ARTN+FALSE
chr1144053662TG0.00173.FALSE
chr553841238GT0.00267SNX18+FALSE
chr1200375418CT0.00671ZNF281-FALSE
chr13545192CG0.00011TPRG1L+FALSE
chr146075724AG1.14407E-05NASP+TRUEAluSx4SINE,Alu
chr369104669CT0.00113UBA3-FALSE
chr1109816293GC0.00759CELSR2+FALSE
chr1075009720TC0.00016DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr1670284570AC0.00028EXOSC6-FALSEAluSxSINE,Alu
chr121766776GC0.00343NBPF3+FALSE
chr1939874945TC0.00335SAMD4B+FALSE
chr1256510709GA0.00047RPL41+FALSE
chr116203171CT3.13656E-06SPEN+FALSE
chr642856959AG6.63353E-07RPL7L1+TRUEAluSpSINE,Alu
chr11769459TC0.00082PDDC1-TRUEAluSq2SINE,Alu
chr154493443CA0.00872TMEM59-FALSEAluSz6SINE,Alu
chr1269237057AG0.00259MDM2+TRUE
chr5125961649AG3.29658E-05PHAX+TRUEAluSz6SINE,Alu
chr119934879TC0.00454MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr116890176AC0.00753NBPF1-FALSE
chr7158719106GA0.00048WDR60+FALSE
chr136067784TC1.68158E-09PSMB2-TRUEAluSzSINE,Alu
chr2206987597TC0.00085.FALSEAluJbSINE,Alu
chr1146650542AG0.00172PDIA3P1+FALSE
chr127202963CT0.00106.FALSEAluSq2SINE,Alu
chr1256510697GA0.00055RPL41+FALSE
chr146830447AC0.00168NSUN4+FALSELTR108a_MamSINE,Alu
chr1079552092CT0.00159DLG5-FALSE
chr1117531813TC0.00751PTGFRN+FALSE
chr642045563AG4.21139E-05TAF8+TRUEAluSzSINE,Alu
chr6158517308AG0.00959SYNJ2+FALSE
chr19162234TC0.00896.FALSEAluSxSINE,Alu
chr484525974TC0.00255GPAT3+FALSE(TTGTT)nSINE,Alu
chr11650832AG0.00407CDK11B,CDK11A-FALSE
chr16582470TC0.00370NOL9-TRUEAluSx1SINE,Alu
chr1765334885TC2.77388E-05PSMD12-TRUEAluSqSINE,Alu
chr1145689025AG0.00541NBPF20,NBPF10+TRUEAluSc8SINE,Alu
chr119984461CT0.00112MINOS1-NBL1,NBL1+FALSE
chr116889413TC8.21040E-06NBPF1-TRUEL1MC4SINE,Alu
chr167874697TC0.00305SERBP1-TRUEAluSx3SINE,Alu
chr1352602919AC0.00117ALG11,UTP14C+FALSE
chr425253995CT9.95051E-10PI4K2B+FALSE
chr110042987AG8.46336E-05NMNAT1+TRUEAluScSINE,Alu
chr457326315AG0.00281PAICS+TRUEAluJrSINE,Alu
chr9115447534TC0.00203INIP-TRUEAluJbSINE,Alu
chr111084104GA0.00116TARDBP+FALSE
chr811700373TC0.00212CTSB-TRUEAluSq2SINE,Alu
chr3179117270TC0.00478GNB4-TRUEAluSzSINE,Alu
chr237327670TC0.00297.FALSE
chr2143638993CG0.00016KYNU+FALSE
chr116952896GA2.20079E-06CROCCP2-FALSE
chr1207942509AG0.00177CD46+TRUEAluSg4SINE,Alu
chr2232328545CT0.00581NCL-FALSE
chr366430375TA0.00091LRIG1-FALSE
chr417633798AG0.00053FAM184B-FALSEAluSzSINE,Alu
chr29629306GT0.00255ADAM17-FALSE
chr314985983AT6.81677E-14FGD5-AS1-FALSE
chr128835934AG0.00193SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1015119789TC0.00366ACBD7-TRUEAluSx1SINE,Alu
chr193617404TG0.00265TMED5-FALSE
chr19328102AG7.16435E-05H6PD+TRUEAluJrSINE,Alu
chr131838550TA0.00595FABP3-FALSE
chr312942852CA0.00458IQSEC1-FALSE
chr2025428587AG0.00018GINS1+TRUEAluJbSINE,Alu
chr1161932324AG0.00104ATF6+FALSE
chr1109818161CT0.00840CELSR2+FALSE
chr1200375846GT0.00061ZNF281-FALSE(T)nSINE,Alu
chr765619292AG0.00189CRCP+TRUEAluSz6SINE,Alu
chr187328403AT0.00235SEP15-FALSE
chr1269158881AG0.00219SLC35E3+TRUEAluSpSINE,Alu
chr132661578CT0.00694TXLNA+FALSE(T)nSINE,Alu
chr1939981168AG0.00446TIMM50+TRUEAluJrSINE,Alu
chr110517688TC0.00179.FALSEAluSx1SINE,Alu
chr128836975AG0.00023SNHG3,RCC1+TRUEAluScSINE,Alu
chr5125961447AG0.00563PHAX+TRUEAluSz6SINE,Alu
chr642856131AG0.00062RPL7L1+TRUEAluSzSINE,Alu
chr3179116220TC0.00233GNB4-TRUEAluSz6SINE,Alu
chr1749041692TC2.35976E-05SPAG9-TRUEAluSxSINE,Alu
chr1206637133CT0.00909SRGAP2+FALSE
chr2217498311TC0.00977IGFBP2+FALSE(CCG)nSINE,Alu
chr2217366534AG0.00700.FALSEAluSzSINE,Alu
chr344839350AC0.00837KIF15+FALSE
chr344791553TC1.10852E-07KIAA1143-TRUEAluJrSINE,Alu
chr13654747CA0.00691TP73-AS1-FALSE
chr2238499528TG0.00332RAB17-FALSE
chr285548075CA0.00932TGOLN2-FALSE
chr195660018TA0.00052TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr1646614656TA0.00565SHCBP1-FALSE
chr4169911126CA0.00122CBR4-FALSE
chr114159457AG0.00764RRM1+FALSE
chr3156258389TC0.00179SSR3-TRUEAluYk3SINE,Alu
chr186986259GA5.32960E-05LAMA1-FALSE
chr124296874GA0.00627.FALSEAluSgSINE,Alu
chr1569983GA0.00076.FALSE
chr76063467GA0.00620EIF2AK1-FALSE
chr574669972CT0.00113COL4A3BP-FALSE
chr146075791AG0.00120NASP+TRUEAluSx4SINE,Alu
chr145975628AG0.00413MMACHC+TRUEAluSx4SINE,Alu
chr239009427AG0.00673.FALSEAluSx3SINE,Alu
chr136067886TC0.00786PSMB2-TRUEAluSzSINE,Alu
chr140435513CA0.00656MFSD2A+FALSE
chr729960211CA0.00034SCRN1-FALSE
chr299812988AG8.76694E-05MRPL30+TRUEAluJbSINE,Alu
chr1156206121GA0.00423PMF1-BGLAP,PMF1+FALSE
chr341281407GT0.00288CTNNB1+FALSE
chr139317318CA1.55431E-15RRAGC-FALSE
chr1145289875TC0.00160NBPF20+FALSEMIRSINE,Alu
chr179126336CG1.94494E-06IFI44+FALSE
chr7937828GA0.00605ADAP1-FALSE
chr14103372465CA0.00600TRAF3+FALSE(AC)nSINE,Alu
chr630692305AG0.00500.FALSEL2aSINE,Alu
chr42940347TC0.00113NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr152816612TC0.00890CC2D1B-TRUEAluSx1SINE,Alu
chr1118165973CT3.23914E-05FAM46C+FALSE
chr129443675TC0.00190EPB41+FALSE
chr16283306TC0.00505ICMT-TRUEAluSx3SINE,Alu
chr265496075CT0.00972ACTR2+FALSE
chr116929327CT0.00646NBPF1-FALSEERVL-E-intSINE,Alu
chr1629454288TC9.60363E-06SMG1P6,BOLA2-SMG1P6-FALSETigger4aSINE,Alu
chr3126755134CT0.00920PLXNA1+FALSE
chr120978516TC0.00774PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr153291425AG0.00507ZYG11B+TRUEAluJrSINE,Alu
chr457326126AG0.00790PAICS+TRUEAluJrSINE,Alu
chr1742877584TC0.00489GJC1-TRUEAluSgSINE,Alu
chr11662754TC0.00856SLC35E2-TRUEAluYSINE,Alu
chr1202992954TC0.00042TMEM183A+FALSE
chr717384393AG1.74996E-06AHR+TRUEAluSxSINE,Alu
chr2183601110TG0.00824DNAJC10+FALSE
chr7138764145TC0.00399ZC3HAV1-FALSE
chr167874859TC0.00071SERBP1-TRUEAluSxSINE,Alu
chr4843695AG0.00602GAK-FALSE
chr1113212974AT0.00424CAPZA1+FALSE
chr155541174AG0.00038USP24-FALSE
chr4155457051AT0.00378PLRG1-FALSEL2d2SINE,Alu
chr1161338504CG0.00343.FALSE
chr1180991777TC0.00629STX6-FALSE
chr1144816555CT0.00530NBPF20,NBPF9+FALSE
chr133149486AG0.00874SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr10100177984CT6.55965E-05HPS1-FALSE
chr811701429TC0.00496CTSB-TRUEAluSx1SINE,Alu
chr7100031502CT0.00091MEPCE+FALSE
chr1017275583TC0.00374VIM+FALSE
chr132508534AG0.00666KHDRBS1+FALSE
chr1169101274TG0.00026ATP1B1+FALSE(T)nSINE,Alu
chr19160989TC0.00183.FALSEAluJbSINE,Alu
chr1108742130TC1.29742E-06SLC25A24-FALSE
chr128930023GA0.00037TAF12-FALSE
chr5134236287AG0.00538TXNDC15+TRUEAluSqSINE,Alu
chr18045340CA0.00059PARK7+FALSE
chr1144598755GA0.00743NBPF20+FALSE
chr730536611TC0.00421GGCT-FALSE
chr116945027TC0.00819CROCCP2-FALSEL1ME3CzSINE,Alu
chr1542707317AT8.30558E-05ZNF106-FALSE
chr568850922GC0.00323OCLN+FALSEAluSx4SINE,Alu
chr297020049TC0.00070NCAPH+FALSE
chr1144521099AG0.00196NBPF20+FALSE
chr2203742141TC0.00044.FALSEAluJbSINE,Alu
chr1144833382CT0.00325NBPF20+FALSEL1MEcSINE,Alu
chr3156259299TC0.00097SSR3-TRUEAluSq2SINE,Alu
chr19642827GA0.00985SLC25A33+FALSE
chr10102308803GC0.00324HIF1AN+FALSE(GT)nSINE,Alu
chr1144851999AC0.00385NBPF20,PDE4DIP+,-FALSE
chr1053456599AG0.00339PRKG1,CSTF2T+,-FALSE
chr110517567TC0.00262.FALSEAluSx1SINE,Alu
chr237331037TC0.00036.FALSEAluSx1SINE,Alu
chr755433880GC0.00778LANCL2+FALSE
chr5125962354AG3.71532E-05PHAX+TRUEAluScSINE,Alu
chr348787684TC0.00813PRKAR2A-TRUEAluSpSINE,Alu
chr2223807817AC0.00991ACSL3+FALSE(A)nSINE,Alu
chr6150046603TC0.00730NUP43-TRUEAluSq2SINE,Alu
chr110520153TC0.00398.FALSEAluSxSINE,Alu
chr110517314TC0.00802.FALSEAluJrSINE,Alu
chr116928622CA0.00011NBPF1-FALSE
chr553841240AG0.00416SNX18+FALSE
chr5125962568AG0.00015PHAX+TRUEAluSzSINE,Alu
chr5125961647AG1.53189E-07PHAX+FALSEAluSz6SINE,Alu
chr2201842391TC0.00081FAM126B-TRUEAluJbSINE,Alu
chr14103372469AC0.00683TRAF3+FALSE(AC)nSINE,Alu
chr128835847AG0.00042SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1226333561AG0.00373ACBD3-FALSE
chr1201488170AG0.00997.FALSEAluSzSINE,Alu
chr231557839GT0.00014XDH-FALSEAluJrSINE,Alu
chr1757279167AG0.00071PRR11+TRUEAluSq2SINE,Alu
chr6150047370TC0.00154NUP43-TRUEAluScSINE,Alu
chr1120612037TG0.00044NOTCH2-FALSE(CGC)nSINE,Alu
chr568858545CG0.00034GTF2H2C,GTF2H2C_2+FALSEAluSzSINE,Alu
chr1212277584GC0.00997DTL+FALSE
chr3149683506GC0.00147PFN2-FALSE
chr346007825TC4.58354E-06FYCO1-FALSE
chr121545089CT0.00834ECE1-FALSEAluSx1SINE,Alu
chr299813003AG0.00370MRPL30+TRUEAluJbSINE,Alu
chr1028971535TA0.00169BAMBI+FALSE
chr1168523472TC0.00649CPT1A-TRUEAluSqSINE,Alu
chr11252513TC0.00670CPSF3L-TRUEAluSpSINE,Alu

Differential Expression Gene Analysis