Dataset Overview
RBPLIN28B
Knock-MethodshRNA
RBP FamilyCSD
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR598YQX
PlatformHiSeq
Pubmed ID32252787

LIN28B - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of LIN28B
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of LIN28B


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr456294628TC0.00234CLOCK-FALSE
chr158999651TG0.00484OMA1-FALSE
chr1142688506TC0.00337.FALSE
chr345722047AG0.00085LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr170904800GT0.00772CTH+FALSE
chr136067925TC1.81623E-06PSMB2-TRUEAluSzSINE,Alu
chr1173793106CT0.00772CENPL-FALSE
chr1109746728AG0.00171KIAA1324+TRUEAluJbSINE,Alu
chr1114939633GA0.00188TRIM33-FALSE
chr1913883548AG0.00566MRI1+TRUEAluYk3SINE,Alu
chr224225006AG0.00078.FALSEAluSxSINE,Alu
chr146164678TC0.00773IPP-TRUEAluJbSINE,Alu
chr330047174AT0.00556RBMS3+FALSE
chr1201860626AG0.00599SHISA4+FALSE
chr314526649TG0.00260SLC6A6+FALSE
chr1210029539GA0.00231DIEXF+FALSE
chr1205683408CT0.00082NUCKS1-FALSE
chr454244053GC0.00726FIP1L1+FALSE(CGGAG)nSINE,Alu
chr1100676277AG0.00135DBT-FALSE
chr122352040GT0.00255LOC101928043,LINC00339+,-FALSE
chr653363500GT0.00684GCLC-FALSE
chr275120159CT0.00180HK2+FALSE
chr192941357AG0.00296GFI1-FALSE
chr151434560GA0.00685CDKN2C+FALSE
chr113942884AC0.00016PDPN+FALSE
chr25837878GA7.66453E-07SOX11+FALSE
chr457327092AG0.00091PAICS+TRUEAluSx1SINE,Alu
chr7157129834CG1.26796E-05DNAJB6+FALSE
chr2101622887GA0.00711RPL31+FALSE
chr2191555980TA0.00913NAB1+FALSE
chr1075008797TC0.00824DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chrX123045405AG0.00551XIAP+TRUEAluJoSINE,Alu
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr1138266CT7.30419E-05LOC729737-FALSE
chr1246931057AG0.00048SCCPDH+FALSE
chr2174090631AC0.00038ZAK,MLK7-AS1+,-FALSE
chr642856007AG0.00212RPL7L1+TRUEAluSzSINE,Alu
chr1761897188GT0.00465FTSJ3-FALSE
chr439550981TC5.85020E-07UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr342252924GC0.00079TRAK1+FALSE
chr1144828688CT0.00024NBPF20,NBPF9+FALSE
chr51317949CT0.00173CLPTM1L-FALSE
chr5172461896TA0.00335ATP6V0E1+FALSE
chr185785549TC0.00320DDAH1-FALSE
chr178414285TA0.00179FUBP1-FALSE
chrX123046302AG0.00649XIAP+TRUEAluJbSINE,Alu
chr9132268259AG0.00032LINC00963+TRUEAluJbSINE,Alu
chr2178406763TC0.00452AGPS+FALSE
chr1161141432CG0.00508B4GALT3-FALSE
chr255255314AC0.00638RTN4-FALSE
chr138174185GT0.00020CDCA8+FALSE
chr1474526154TC0.00030BBOF1,ALDH6A1+,-FALSEAluSpSINE,Alu
chr1145826918GC0.00829NBPF20,NBPF10,GPR89A+,-FALSE
chr2174090636TA0.00043ZAK,MLK7-AS1+,-FALSE
chr1962927GA0.00358WASH5P-FALSE
chr1158057633CG0.00031KIRREL+FALSE
chr136067817TC1.59583E-06PSMB2-TRUEAluSzSINE,Alu
chr1171501831AG0.00040PRRC2C+FALSE
chr116945409TA0.00105CROCCP2-FALSE
chr193803522TC0.00163CCDC18-AS1-TRUEAluJrSINE,Alu
chr225044957GA0.00651CENPO,ADCY3+,-FALSE
chr178414310CA0.00131FUBP1-FALSE
chr2114352179GA1.68965E-05WASH2P+FALSE
chr159122056GC1.57132E-06MYSM1-FALSE
chr1900505GC0.00583KLHL17+FALSE
chr353265957TC0.00493TKT-FALSE
chr2217366896AG0.00457.FALSEAluSz6SINE,Alu
chr1229493734CT0.00163ERGIC2-FALSE
chr568936027GA0.00868.FALSE
chr145976262AC0.00010MMACHC+FALSE
chr41305799CT0.00730MAEA+FALSE
chrX77083116TC0.00658MAGT1-TRUEAluSgSINE,Alu
chr3179042832AG0.00308ZNF639+TRUEAluSpSINE,Alu
chr154571374AG0.00916TCEANC2+TRUEAluScSINE,Alu
chr116893691CA0.00371NBPF1-FALSE
chr1200375848CT0.00586ZNF281-FALSE(T)nSINE,Alu
chr5178986978CG0.00341RUFY1+FALSE
chr1160990876CA1.09997E-06F11R-FALSE
chr1233518885TC0.00021MLK4+FALSE(TTTC)nSINE,Alu
chr124746451AG0.00683NIPAL3+TRUEAluScSINE,Alu
chr3172351006CG6.14326E-06NCEH1-FALSE
chr1331033316TA0.00497HMGB1-FALSE
chr261764922GC0.00679XPO1-FALSE
chr1145513114AG0.00026NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr357613144TC0.00959DENND6A,PDE12+,-FALSEAluSzSINE,Alu
chr1765334856TC1.38810E-06PSMD12-TRUEAluSqSINE,Alu
chr1204521590AG1.33621E-05MDM4+TRUEAluSgSINE,Alu
chr187328403AT0.00235SEP15-FALSE
chr3142776250AC0.00926U2SURP+FALSE
chr1149913513TC0.00495OTUD7B-TRUEMER96BSINE,Alu
chr1100654773TC0.00810DBT-TRUEAluSzSINE,Alu
chr642856105AG0.00972RPL7L1+TRUEAluSzSINE,Alu
chr756131098TA0.00950CCT6A+FALSEL1M5SINE,Alu
chr1150281090AG3.10555E-05MRPS21+TRUEAluSzSINE,Alu
chr168940885GA0.00022DEPDC1-FALSEMIRSINE,Alu
chr146830430GA0.00023NSUN4+FALSELTR108a_MamSINE,Alu
chr243625184TA0.00587THADA-FALSE
chr1570178GA0.00787.FALSE
chr611185161CT0.00297NEDD9-FALSE
chr315112510TC0.00710RBSN-FALSEAluSq2SINE,Alu
chr2202242616GA0.00880TRAK2-FALSE
chr1233514975GT0.00584MLK4+FALSE
chr425279508GA3.42130E-11PI4K2B+FALSE
chr110520383TC0.00401.FALSEAluSx1SINE,Alu
chr261416411TG0.00146USP34-FALSEAluSc8SINE,Alu
chr140539213AG0.00693PPT1-FALSE
chr11769883TC0.00631PDDC1-TRUEAluYSINE,Alu
chr8144684474TC0.00058.FALSE
chr348787042TC0.00799PRKAR2A-TRUEAluSx3SINE,Alu
chr154692341TC0.00045SSBP3-FALSE(T)nSINE,Alu
chr1538643574TC0.00455SPRED1+FALSE
chr1204525713AG0.00501MDM4+TRUEAluSzSINE,Alu
chr483351845GT0.00422ENOPH1+FALSE
chr7115898258AT0.00314TES+FALSE(T)nSINE,Alu
chr2191745647CT2.95764E-05GLS+FALSE
chr9130268407CG0.00902FAM129B-FALSE(CTCA)nSINE,Alu
chr8144940794GC0.00038EPPK1-FALSE
chr6160526905CA0.00268IGF2R+FALSE
chr1223967953CT0.00341TP53BP2-FALSE
chr8124262076GT0.00115ZHX1-C8orf76,ZHX1-FALSE
chr1469704553GT7.62587E-05EXD2+FALSE
chr167874859TC0.00027SERBP1-TRUEAluSxSINE,Alu
chr5139931626TG0.00490SRA1-FALSE
chr10101992425TC0.00406CWF19L1-TRUEAluSq2SINE,Alu
chr1113672691AG0.00515.FALSEAluJbSINE,Alu
chr76064009CG0.00273EIF2AK1-FALSE
chr2206987629TC0.00491.FALSEAluJbSINE,Alu
chr119566382AG0.00513LOC101927895,EMC1+,-FALSE
chr7128169979TG0.00569.FALSE
chr42940397TC0.00010NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr537290323TC8.21848E-08.FALSEAluSzSINE,Alu
chr1114438951AG0.00012AP4B1-AS1,AP4B1+,-FALSE
chr232539582AG0.00419.FALSEAluSpSINE,Alu
chr1916663345TC0.00304SLC35E1-TRUEAluSgSINE,Alu
chr1131452750AG0.00326DNAJC24+TRUEAluSx1SINE,Alu
chr1138356CA0.00199LOC729737-FALSE
chr167874689TC1.54545E-05SERBP1-TRUEAluSx3SINE,Alu
chr310193511AG0.00116VHL+TRUEAluJrSINE,Alu
chr136770601GT0.00055THRAP3+FALSE(T)nSINE,Alu
chr4119956116GT0.00442SYNPO2+FALSE
chr133148213AG0.00958SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr333907915AG3.74419E-09PDCD6IP+FALSE
chr110221302GA0.00119UBE4B+FALSE
chr1680636808CT0.00881CDYL2-FALSE
chr2250745987CG0.00683PLXNB2-FALSE
chr136068370TC0.00067PSMB2-TRUEAluScSINE,Alu
chr111159823TC0.00186EXOSC10,LOC105376736+,-FALSE
chr1101444791CT0.00268SLC30A7+FALSE
chr1148003752TC3.77288E-10NBPF8-TRUEL1MC4SINE,Alu
chr1718111804TG0.00487ALKBH5+FALSE(TTTTGTT)nSINE,Alu
chr167874689TC0.00053SERBP1-TRUEAluSx3SINE,Alu
chr16283264TC0.00284ICMT-TRUEAluSx3SINE,Alu
chr115896199GA0.00483DNAJC16+FALSEAluSpSINE,Alu
chr110364612AC0.00860KIF1B+FALSE
chr131732599TG0.00827SNRNP40-FALSE
chr3196771049TC0.00010DLG1-FALSE
chr1113673737AG0.00798.FALSEAluSx1SINE,Alu
chr13545192CG0.00011TPRG1L+FALSE
chr17263417CT0.00675LOC105371430,C17orf97+,-FALSE
chr425279320GA1.66733E-12PI4K2B+FALSE
chr1244182706AG0.00788IRAK4+FALSEMSTB-intSINE,Alu
chr19161199TC0.00468.FALSEAluSxSINE,Alu
chr11684346GC0.00504NADK-FALSE
chr2232319612AT5.77221E-05NCL-FALSE
chr1212967264CG0.00781DDX47+FALSE
chr1762541203GA0.00660SMURF2-FALSE
chr237076498AC0.00797STRN-FALSE
chr11683565GA7.19943E-05NADK-FALSE
chr439550967TC2.19217E-06UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr711148863TA0.00455PHF14+FALSE
chr110517300TC0.00011.FALSEAluJrSINE,Alu
chr133148045AG0.00264SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr388199298TC0.00048C3orf38+FALSE
chr613788342TC0.00048MCUR1-TRUEAluSxSINE,Alu
chr13545194CG0.00176TPRG1L+FALSE
chr167874696TC0.00098SERBP1-TRUEAluSx3SINE,Alu
chr581571878AT8.61300E-05RPS23-FALSE
chr120977380TC0.00429PINK1,PINK1-AS+,-FALSE
chr132661594CT0.00725TXLNA+FALSE(T)nSINE,Alu
chr1619715588TC0.00063.FALSEAluSgSINE,Alu
chr142693597AG0.00106FOXJ3-FALSE
chr1207942509AG0.00177CD46+TRUEAluSg4SINE,Alu
chr261278030AG0.00218PEX13+TRUEAluYSINE,Alu
chr631657413TC0.00066.FALSE
chr286252043TC0.00909POLR1A-TRUEAluSq2SINE,Alu
chr1773703945CT0.00242SAP30BP+FALSEMIRcSINE,Alu
chr537290554TC0.00010.FALSEAluSzSINE,Alu
chr119542410TC0.00270LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr3196728813CT0.00068MELTF-FALSE
chr3160286646CT0.00086.FALSE
chr1118066724AT0.00979MAN1A2+FALSE
chr4177252327AG3.52508E-05SPCS3+TRUE
chr146828657CT0.00378NSUN4+FALSE
chr1749041827TC0.00125SPAG9-TRUEAluSxSINE,Alu
chr1918475303AG0.00757PGPEP1+TRUEAluSx1SINE,Alu
chr315113655TC6.08503E-07RBSN-TRUEAluSz6SINE,Alu
chr232535747AG0.00250.FALSEAluJbSINE,Alu
chr349315588TG0.00182USP4-FALSE
chr1154179193AT0.00122C1orf43-FALSE
chr120982216TA0.00065DDOST-FALSE
chr7129251289CT0.00808.FALSE
chr593018903TA5.97109E-08FAM172A-FALSE(TCA)nSINE,Alu
chr211323108TA0.00100ROCK2-FALSE(TA)nSINE,Alu
chr3179117241TC0.00133GNB4-TRUEAluSzSINE,Alu
chr2183601110TG0.00824DNAJC10+FALSE
chr1590820104AG4.84304E-05.FALSEAluYSINE,Alu
chr138326774TC0.00664INPP5B-TRUEAluJrSINE,Alu
chr316357708AG0.00098RFTN1-FALSE
chr9131457814GA0.00021SET+FALSE
chr116932429CG0.00823NBPF1-FALSEL1MC2SINE,Alu
chr388199298TC0.00112C3orf38+FALSE
chr7128829066AG0.00816SMO+FALSE
chr110042911AG0.00043NMNAT1+TRUEAluScSINE,Alu
chr724731065CT0.00414MPP6+FALSE(TGTATG)nSINE,Alu
chr1474526976TC0.00469BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr717384880AG0.00027AHR+TRUEAluScSINE,Alu
chr110519910TC7.27344E-07.FALSEAluJrSINE,Alu
chr310192753AG0.00069VHL+TRUEAluSx1SINE,Alu
chr1145689566AG0.00331NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr1144594308GA0.00577NBPF20+FALSE
chr1143399333TA0.00339.FALSEL1MC4SINE,Alu
chr1338936619GT0.00212UFM1+FALSE

Differential Expression Gene Analysis