Dataset Overview
RBPSRSF1
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR094KBY
PlatformHiSeq
Pubmed ID32252787

SRSF1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SRSF1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SRSF1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr328390351AG1.14010E-06AZI2-FALSE
chr1146650289CT0.00736PDIA3P1+FALSE
chr286850798AG0.00267RNF103-CHMP3,RNF103-FALSE
chr110521260TC0.00658DFFA-TRUEAluYSINE,Alu
chr255452459GT5.59903E-07CLHC1-FALSE
chr722765456GT5.19964E-05LOC541472-FALSE
chr1298943033AG0.00346TMPO+TRUEAluSzSINE,Alu
chr116893691CA0.00141NBPF1-FALSE
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr1225360465GA0.00074KRAS-FALSE
chr7115898442GC2.36867E-05TES+FALSEAluSxSINE,Alu
chrX2824343TC0.00108ARSD-TRUEAluJbSINE,Alu
chr174929863AG0.00597KIF1C+TRUEAluJbSINE,Alu
chr116892135GA0.00508NBPF1-FALSE
chr116958064AG0.00446.FALSE
chr170718276GT0.00836.FALSE
chr373115786TC3.88619E-05PPP4R2+FALSE
chr1120166681GA0.00241ZNF697-FALSE
chr76064010CA0.00304EIF2AK1-FALSE
chr117345245CT0.00812SDHB-FALSE
chr119542679TC0.00738LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr1110564996CT0.00926AHCYL1+FALSE
chr2203742141TC0.00044.FALSEAluJbSINE,Alu
chr12124146067AG1.77884E-06GTF2H3+TRUEAluSx4SINE,Alu
chr314175262TC3.06250E-10TMEM43+FALSE
chr118709315AG0.00307RPL27A+TRUEAluYk2SINE,Alu
chr1144874760TC0.00267NBPF20,PDE4DIP+,-FALSE
chr1110950295CA0.00359LAMTOR5-FALSE
chr286249930TC0.00054LOC90784-TRUEAluJrSINE,Alu
chr8144684474TC0.00058.FALSE
chr132799439CT0.00239MARCKSL1-FALSE
chr1202993056TC0.00046TMEM183A+FALSE
chr1183218871GT0.00025NMNAT2-FALSE
chr1214524509AG0.00471PTPN14-FALSEAluSgSINE,Alu
chr133086876TC0.00104ZBTB8OS-TRUEAluYSINE,Alu
chr1894375GA0.00052NOC2L-FALSE
chr9132266648AG0.00230LINC00963+TRUEAluSxSINE,Alu
chr13730400TC0.00457CEP104-TRUEAluSx3SINE,Alu
chr1075008815TC5.77576E-09DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr1061548859AC0.00011CCDC6-FALSE
chr136068237TC0.00054PSMB2-TRUEAluScSINE,Alu
chr4155457049TA0.00434PLRG1-FALSEL2d2SINE,Alu
chr168902411AG0.00357PMM2+FALSE
chr2162165008AT0.00539PSMD14+FALSE
chr119953120GA0.00027MINOS1,MINOS1-NBL1+FALSE
chr268402794TG0.00630PNO1+FALSE
chr1148003752TC0.00015NBPF8-TRUEL1MC4SINE,Alu
chr1959093997AG0.00047CENPBD1P1+TRUEAluYSINE,Alu
chr124999101GT0.00100SRRM1+FALSE
chr119543459TC0.00395LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr265496187GA0.00266ACTR2+FALSE
chr2147676711GA0.00316MCM3AP-FALSE
chr1168169452GA0.00600TIPRL+FALSE
chr255516903GA3.31807E-05CCDC88A-FALSE(GA)nSINE,Alu
chr1118502732CT0.00151WDR3,SPAG17+,-FALSE
chr133148698AG0.00736SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr7154796171GA0.00066PAXIP1-AS1+FALSEAluSx3SINE,Alu
chr19160900TC0.00893.FALSEAluJbSINE,Alu
chr126603883GA0.00660CEP85+FALSE
chr2101635538CT0.00069TBC1D8,RPL31+,-FALSECharlie17SINE,Alu
chr1121133770AG0.00295SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr274349080AG0.00094.FALSEAluSzSINE,Alu
chr16582558TC0.00030NOL9-TRUEAluSx1SINE,Alu
chr124296849TC0.00125.FALSE
chr1757279281AG0.00055PRR11+TRUEAluSq2SINE,Alu
chr128930023GA0.00037TAF12-FALSE
chr111188109CA0.00817MTOR-FALSE
chr1847919174AG0.00820SKA1+TRUEAluYk4SINE,Alu
chr1150939883AG0.00472CERS2-FALSE
chr12282776GC0.00011MORN1,LOC100129534-FALSE
chr153291420AG0.00011ZYG11B+TRUEAluJrSINE,Alu
chr127204447TC0.00513.FALSEAluSg7SINE,Alu
chr581571877CT0.00250RPS23-FALSE
chr348787633TC0.00287PRKAR2A-TRUEAluSpSINE,Alu
chr537291636TC0.00518.FALSEAluSx3SINE,Alu
chr1765334856TC1.38810E-06PSMD12-TRUEAluSqSINE,Alu
chr744917351TC0.00338PURB-TRUEAluSzSINE,Alu
chr1656510334TC0.00494OGFOD1+FALSE
chr1681420621GC0.00214.FALSEL3bSINE,Alu
chr3121351287AG0.00656HCLS1-FALSE
chr1155851620AG6.99218E-05SYT11+TRUEAluSq2SINE,Alu
chr228002599TA0.00566MRPL33+FALSE
chr16683581AC0.00126PHF13+FALSE
chr116918734GC0.00083NBPF1-FALSE
chr275883878TC0.00838MRPL19+FALSEHAL1SINE,Alu
chr1145281633CA0.00510NBPF20,NOTCH2NL+FALSE
chr349571462GT0.00032DAG1+FALSE
chr120826781CT1.74444E-05MUL1-FALSE
chr1779838088TC6.81311E-05.FALSEAluSxSINE,Alu
chr3195411991CA0.00058SDHAP2+FALSE
chr5110463616GT0.00264WDR36+FALSE(T)nSINE,Alu
chr12133298053AG7.95391E-05PGAM5+TRUEAluJoSINE,Alu
chr116892277GT0.00021NBPF1-FALSE
chr3196079691TC0.00507.FALSEAluScSINE,Alu
chr237329369TC0.00010.FALSEAluJr4SINE,Alu
chr1202697335GA0.00374KDM5B-FALSE
chr2203742324TC0.00482.FALSEAluJbSINE,Alu
chr1204525548AG0.00501MDM4+TRUEAluSzSINE,Alu
chr439550981TC5.85020E-07UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr136067817TC0.00339PSMB2-TRUEAluSzSINE,Alu
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr135649804CA0.00127SFPQ-FALSE
chr314986104TC6.84901E-10FGD5-AS1-TRUEFLAM_CSINE,Alu
chr133148623AG0.00221SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr129519712TC0.00017MECR-TRUEAluJbSINE,Alu
chr1101442569CA0.00567SLC30A7+FALSE
chr127202812TC0.00353.FALSEAluSq2SINE,Alu
chr11655474GA0.00694CDK11B,CDK11A-FALSE
chr119542456TC0.00193LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu
chr1924103951AG0.00082ZNF726+TRUEAluSg4SINE,Alu
chr1145509570AG0.00037NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr123519504TA3.21384E-05HTR1D-FALSE
chr41305799CT0.00730MAEA+FALSE
chr5122165503AT0.00170SNX2+FALSE(AC)nSINE,Alu
chr642856100AG0.00048RPL7L1+TRUEAluSzSINE,Alu
chr16582701TC1.54245E-05NOL9-TRUEAluSgSINE,Alu
chr110520076TC0.00763.FALSEAluSxSINE,Alu
chr14105237680GC6.20821E-05AKT1-FALSE
chr1180082703CA2.04280E-05CEP350+FALSE
chr161922501AC0.00231NFIA+FALSEA-richSINE,Alu
chr15102516561TC0.00805WASH3P+FALSE
chr1241796949GA0.00053OPN3,CHML-FALSE
chr116952481AG5.15865E-05CROCCP2-FALSE
chr344791062TC0.00035KIAA1143-FALSE
chr928607TC0.00146WASH1-FALSE
chr2238678002CG0.00711LRRFIP1+FALSE
chr11344998AG0.00235.FALSEAluSgSINE,Alu
chr115896199GA0.00483DNAJC16+FALSEAluSpSINE,Alu
chr2101186088CT0.00817PDCL3+FALSE
chr162553869AT0.00089TBC1D24+FALSE
chr116891365GA0.00609NBPF1-FALSE
chr1194801637TC0.00726SRSF8+FALSE
chr1115313038GA0.00144SIKE1-FALSE
chr110177553CG0.00474UBE4B+FALSE
chr456295160TA0.00576CLOCK-FALSE(T)nSINE,Alu
chr152817504TC0.00934CC2D1B-TRUEAluSg4SINE,Alu
chr1269237019AG2.84819E-05MDM2+TRUE
chr1121133779CG0.00567SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr1244572643CA0.00560ADSS-FALSE
chr19160963TC0.00098.FALSEAluJbSINE,Alu
chr4165999188TC0.00751TMEM192-TRUEFLAM_CSINE,Alu
chr310320968TA0.00237TATDN2+FALSE
chr1117530188AG0.00199PTGFRN+FALSE
chr131405707GT0.00431PUM1-FALSE
chr11653093AG0.00642CDK11B,CDK11A-FALSEL2SINE,Alu
chr4165998642TC0.00021TMEM192-TRUEAluSgSINE,Alu
chr237479023GA0.00063PRKD3-FALSE
chr119543356TC0.00110LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1155851620AG0.00066SYT11+TRUEAluSq2SINE,Alu
chr2230629138CT0.00958TRIP12-FALSE
chr119586455AG0.00772MRTO4+TRUEAluSzSINE,Alu
chr1144614931GA0.00469NBPF20+FALSE
chr2025427865AG0.00018GINS1+FALSEAluSzSINE,Alu
chr1431916783TC3.40362E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr1160990875TC9.42851E-06F11R-FALSE
chr136068295TC0.00910PSMB2-TRUEAluScSINE,Alu
chr9125866691AC0.00177RABGAP1+FALSE
chr4128756704AG0.00271.FALSEAluSxSINE,Alu
chr2113287424TA0.00616TTL+FALSE
chr1154317153CT0.00567ATP8B2+FALSE
chr1236721608CT0.00286HEATR1-FALSE
chr612120445AG0.00037HIVEP1+FALSE
chr128825418AG0.00046PHACTR4+TRUEAluSgSINE,Alu
chr1173457945GA0.00287PRDX6+FALSE
chr3120114914GA1.07649E-06FSTL1-FALSE
chr1145513114AG0.00033NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr121671943TG0.00471ECE1-FALSE(GCTCCCG)nSINE,Alu
chr124172310CT0.00502FUCA1-FALSE
chr7100279005CA0.00176GIGYF1-FALSE(A)nSINE,Alu
chr413604418GC2.95746E-07BOD1L1-FALSE
chr110521238TC0.00232DFFA-TRUEAluYSINE,Alu
chr1542859452AG0.00123HAUS2+TRUEAluJbSINE,Alu
chr146660295TC0.00871POMGNT1-FALSE
chr1183515428GA0.00232SMG7+FALSE
chr168940887TG0.00293DEPDC1-FALSEMIRSINE,Alu
chr3195451488CT1.73907E-06MUC20+FALSE
chr825272447AT0.00770DOCK5+FALSE
chr345721989AG0.00713LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr310192798AG0.00722VHL+TRUEAluSx1SINE,Alu
chr2178406762GT0.00708AGPS+FALSE
chr133324136TC0.00739S100PBP+FALSE
chr11252687TC0.00459CPSF3L-TRUEAluSpSINE,Alu
chr1079570873GT0.00292DLG5-FALSE
chr19160975TC0.00347.FALSEAluJbSINE,Alu
chr1246577921GT0.00306SLC38A1-FALSE
chr136534024AG0.00635.FALSEFLAM_ASINE,Alu
chr8141461185AG0.00793TRAPPC9-FALSE
chr23592638TC0.00941RNASEH1-TRUEAluSz6SINE,Alu
chr261315734AG0.00396KIAA1841+TRUEAluSgSINE,Alu
chr16603884CG0.00118CAPN15+FALSE
chr1150337289GT0.00298RPRD2+FALSE
chr1474526154TC0.00030BBOF1,ALDH6A1+,-FALSEAluSpSINE,Alu
chr1109475569AG0.00046GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr11661751AG0.00037SLC35E2-FALSE
chr1112266787GT0.00873FAM212B-FALSE
chr146049716TG0.00761NASP+FALSE
chr5151041871CA0.00165SPARC-FALSE
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr232535692AG0.00236.FALSEAluJbSINE,Alu
chr237328042TC6.80414E-06.FALSE
chr5151041884TA0.00101SPARC-FALSE
chr128835934AG0.00069SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr258387000CT0.00027VRK2,FANCL+,-FALSE
chr2217366901AG0.00143.FALSEAluSz6SINE,Alu
chr145987557GC0.00921PRDX1-FALSE
chr133145959TG0.00755SYNC,RBBP4+,-FALSE(T)nSINE,Alu
chr722983600TC0.00025FAM126A-FALSE
chr2114220055TC9.23000E-05CBWD2+FALSE
chr17833544TC0.00186VAMP3+FALSE
chr699848757CT0.00951PNISR-FALSE(TCTTTT)nSINE,Alu
chr174665493GA0.00128FPGT-TNNI3K,FPGT+FALSE
chr144463185TG0.00427SLC6A9-FALSE
chr3196078364GA0.00290.FALSEGA-richSINE,Alu
chr2035409839TC0.00556SOGA1-TRUEAluSxSINE,Alu
chr115818065TC0.00372CASP9-TRUEAluJbSINE,Alu
chr193804952GA0.00421CCDC18-AS1-FALSE
chr3195393406CT0.00690SDHAP2+FALSE
chr2207146629AG0.00434ZDBF2+FALSE
chr121780000GT0.00153NBPF3+FALSEERVL-E-intSINE,Alu
chr128825465AG0.00756PHACTR4+TRUEAluSgSINE,Alu
chr1168218494AG0.00317.FALSEAluSzSINE,Alu
chr3100083423TC0.00678TOMM70-FALSEFAMSINE,Alu
chr342592902TC0.00934SEC22C-FALSEAluJrSINE,Alu
chr362282908CT0.00281PTPRG-AS1-FALSE
chr16283558AT0.00624ICMT-FALSE
chr116889596TC0.00093NBPF1-TRUE
chr44291832AT6.49020E-08LYAR-FALSE
chr1151862656TC0.00933THEM4-TRUEAluSpSINE,Alu
chr5122359498AC0.00038PPIC-FALSE(AC)nSINE,Alu
chr1178887208AT0.00239RALGPS2+FALSE
chr10865825CT0.00088LARP4B-FALSE
chr116973198GA0.00514MST1P2+FALSE
chr1228881129AG0.00199RHOU+FALSE
chr133149256AG0.00010SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr13545191CT0.00597TPRG1L+FALSE
chr6166824706AT0.00048RPS6KA2-FALSE(T)nSINE,Alu
chr1063829539CT0.00918ARID5B+FALSE
chr1921474857TC0.00131ZNF708-TRUEAluScSINE,Alu
chr133765752GA0.00963ZNF362+FALSE
chr1226333556CA0.00250ACBD3-FALSE(CAAAA)nSINE,Alu
chr372425248TA0.00281RYBP-FALSE
chr1145689566AG2.12475E-08NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr128661653AG9.75782E-05MED18+TRUEAluSgSINE,Alu
chr124293612GA0.00366.FALSE
chr110042988AG0.00359NMNAT1+TRUEAluScSINE,Alu
chr1179326925CT0.00284SOAT1+FALSEAluJoSINE,Alu
chr175377119AT0.00043DERL2-FALSEFLAM_CSINE,Alu
chr119586458AG7.27253E-05MRTO4+TRUEAluSzSINE,Alu
chr189518120AG0.00453GBP1-FALSE
chr1205583612CA0.00311ELK4-FALSE
chr1523282993GA0.00337HERC2P2-FALSE
chr9125866693CT0.00255RABGAP1+FALSE
chr5180001389GA0.00138CNOT6+FALSE
chr119542631TC0.00176LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr237330620TC0.00216.FALSEAluSq2SINE,Alu
chr1610624926TC0.00029EMP2-TRUEAluSx3SINE,Alu
chr1234561498TC0.00092TARBP1-FALSE
chr1256510697GA0.00055RPL41+FALSE
chr41193026AG0.00471SPON2,LOC100130872-FALSEAluSpSINE,Alu
chr1144931727GA0.00211NBPF20,PDE4DIP+,-FALSE
chr2217366541AG0.00071.FALSEAluSzSINE,Alu
chr1148595665AG0.00378NBPF15+TRUEL1MC4SINE,Alu
chr1145282799GA0.00081NBPF20,NOTCH2NL+FALSE
chr1321547679AG0.00233LATS2-FALSE
chr128825337AG0.00904PHACTR4+TRUEAluSgSINE,Alu
chrX77083915TC0.00075MAGT1-TRUEAluSzSINE,Alu
chr457326291AG0.00424PAICS+TRUEAluJrSINE,Alu
chr1160231113CT0.00204DCAF8-FALSE
chr11570921CT0.00411CDK11B-FALSE
chr129464358AG0.00056LOC642846+FALSE
chr5203683GT0.00399.FALSEMIRbSINE,Alu
chr119934758CG1.75422E-05MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr13371371CG0.00844ARHGEF16+FALSE
chr1168220529AG0.00161.FALSEAluSz6SINE,Alu
chr150906945CT0.00178FAF1-FALSE
chr1466209686TA7.37485E-06FUT8+FALSE(TT)nSINE,Alu
chr1538780594CT0.00135RASGRP1-FALSE
chr1143915747GA0.00603.FALSE
chr1121115958TC0.00147SRGAP2-AS1,SRGAP2D,SRGAP2B,SRGAP2C+,-FALSE
chr1147124310TG0.00968ACP6-FALSE
chr1420923558AC0.00373APEX1+FALSE
chr132158374TC0.00134COL16A1-FALSE
chr15102512797AG0.00080WASH3P+FALSE
chr9131094270AG0.00686COQ4+TRUEAluSxSINE,Alu
chr3169807548TC0.00665PHC3-TRUEAluSx1SINE,Alu
chr110520258TC0.00396.FALSEAluSxSINE,Alu
chr315114353TC8.61483E-05RBSN-TRUEAluYSINE,Alu
chr5131715011AG0.00761SLC22A5+FALSE
chr110518052TC7.90759E-05.FALSEAluJrSINE,Alu
chr116160968CT0.00524FLJ37453-FALSE(T)nSINE,Alu
chr568738649AT0.00716.FALSE
chr138327586CT0.00198INPP5B-FALSEAluSx3SINE,Alu
chr5133918134GT0.00404JADE2+FALSE
chr3120113403TG0.00364FSTL1-FALSE

Differential Expression Gene Analysis