Dataset Overview
RBPTIAL1
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR450VQO
PlatformHiSeq
Pubmed ID32252787

TIAL1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of TIAL1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of TIAL1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1541590287AG0.00319OIP5-AS1+FALSE
chr195658344GA0.00100TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr120978451TC0.00193PINK1-AS,DDOST-TRUEAluYSINE,Alu
chr224494638TG0.00507ITSN2-FALSE(TATCCT)nSINE,Alu
chr3148748380TC0.00240HLTF-FALSE
chr152306066TA0.00154NRDC-FALSE(TCA)nSINE,Alu
chr2242512159AG0.00243BOK+FALSE
chr19160989TC0.00092.FALSEAluJbSINE,Alu
chr1450792837AG0.00550ATP5S+TRUEAluSxSINE,Alu
chr1116237273AG0.00309VANGL1+FALSE
chr1115248084CT0.00171NRAS-FALSE
chr7100804430CT0.00629AP1S1+FALSE
chr1256510697GA0.00055RPL41+FALSE
chr143897496GA0.00481SZT2+FALSE
chr1179829584TC0.00204TOR1AIP2-TRUEAluJrSINE,Alu
chr126774224AG0.00295DHDDS+TRUEAluSz6SINE,Alu
chr1108678732TC0.00396SLC25A24-FALSE
chr1911560483AG0.00775PRKCSH+TRUEAluSxSINE,Alu
chr125894472CG0.00594LDLRAP1+FALSEMIRbSINE,Alu
chr3113370193CT4.09251E-05USF3-FALSEUCON34SINE,Alu
chr479832870AT0.00655BMP2K+FALSE
chr1675479910TC0.00026TMEM170A-TRUEAluSg4SINE,Alu
chr1144481235AG1.18230E-05NBPF20+FALSE
chr1157092835GA0.00595.FALSE
chr11017747AG0.00142C1orf159-FALSE
chr2176790393CT0.00282LNPK-FALSEAluSpSINE,Alu
chr19162348TC0.00359.FALSEAluSxSINE,Alu
chr146075777AG0.00268NASP+TRUEAluSx4SINE,Alu
chr9132268442AG0.00642LINC00963+TRUEAluJbSINE,Alu
chr12120898658AG0.00372GATC+TRUEAluYSINE,Alu
chr19160996TC0.00023.FALSEAluJbSINE,Alu
chr1765335362TC3.02375E-05PSMD12-TRUEAluSxSINE,Alu
chr1145512073AG0.00056NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr5149829068CT0.00038RPS14-FALSE
chrX3523050CA0.00043PRKX-FALSE
chr13545192CG0.00011TPRG1L+FALSE
chr895804615AG0.00968DPY19L4+TRUEAluSq2SINE,Alu
chr1200589813CA0.00034KIF14-FALSE
chr1201846617AC0.00380IPO9+FALSE(CA)nSINE,Alu
chr1207942336AG0.00586CD46+TRUEAluSg4SINE,Alu
chr3148748198GA3.62985E-05HLTF-FALSE
chr2201774341TC0.00073.FALSEAluSzSINE,Alu
chr140214296AG0.00485PPIE+TRUEAluSq2SINE,Alu
chr167874731TC0.00145SERBP1-TRUEAluSx3SINE,Alu
chr153289686AG0.00460ZYG11B+TRUEAluSzSINE,Alu
chr137948912CT0.00084ZC3H12A+FALSE
chr145975574AG0.00299MMACHC+TRUEAluSx4SINE,Alu
chr1145689568AG0.00157NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr267631831GA0.00423ETAA1+FALSE
chr3181430141GC0.00086SOX2-OT,SOX2+FALSE
chr19328242AG5.63395E-05H6PD+TRUEAluJrSINE,Alu
chr116575726TC0.00916FBXO42-FALSE
chr136068281TC0.00331PSMB2-TRUEAluScSINE,Alu
chr1120164252GA0.00139ZNF697-FALSE
chr5109204057TA0.00614MAN2A1+FALSE
chr1658054472TC0.00530USB1+FALSE
chr826435508CT0.00106DPYSL2+FALSE(TC)nSINE,Alu
chr128661657AG0.00910MED18+TRUEAluSgSINE,Alu
chr195392593CT0.00173CNN3-FALSE(GGCGCG)nSINE,Alu
chr3112320485TC0.00107LINC01279-TRUEAluJbSINE,Alu
chr1206669958GA0.00347IKBKE+FALSE
chr178414334CA0.00702FUBP1-FALSEA-richSINE,Alu
chr1144604425CT0.00299NBPF20+FALSE
chr1145513031AG0.00713NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr132373858AT0.00100PTP4A2-FALSE
chr2121979980GA0.00525TFCP2L1-FALSEL1MB8SINE,Alu
chr1148251079TC0.00378NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr138326661TC0.00023INPP5B-TRUEAluJrSINE,Alu
chr1028971535TA0.00169BAMBI+FALSE
chr119934930TC0.00026MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr110520487TC0.00710.FALSEAluSx1SINE,Alu
chr2113334178AT0.00654POLR1B+FALSEL1MA10SINE,Alu
chr1144521099AG0.00196NBPF20+FALSE
chr145976723TC0.00733MMACHC,PRDX1+,-FALSE
chr1118069696TC0.00922.FALSE
chr1109746825AG0.00094KIAA1324+TRUEAluJbSINE,Alu
chr914764CT0.00491WASH1-FALSE
chr2202038657AG0.00354.FALSEAluSx1SINE,Alu
chr116918783CT0.00252NBPF1-FALSE
chr350686350TG2.12445E-05MAPKAPK3+FALSE
chr18045343CA0.00162.FALSE
chr127879800TG0.00473AHDC1-FALSEMIRbSINE,Alu
chr154692334TC0.00021SSBP3-FALSE(T)nSINE,Alu
chr261705067AT0.00084.FALSE
chr1583826212CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr6150045852TC0.00204NUP43-TRUEAluSqSINE,Alu
chr632789807CT0.00281.FALSE
chr41205680CA0.00247CTBP1-AS,CTBP1+,-FALSE
chr1200521297CT0.00133KIF14-FALSE(T)nSINE,Alu
chr132661594CT0.00725TXLNA+FALSE(T)nSINE,Alu
chr298388810GT6.24900E-05TMEM131-FALSE
chr110519947TC0.00184.FALSEAluJrSINE,Alu
chr110517653TC0.00475.FALSEAluSx1SINE,Alu
chr1541597559AG0.00127.FALSEAluSz6SINE,Alu
chr4128958127AG0.00556ABHD18+TRUEAluSx3SINE,Alu
chr171531596AG0.00016ZRANB2-AS1,ZRANB2+,-FALSE
chr1115275398TG0.00474CSDE1-FALSE
chr145241587GA0.00248RPS8,SNORD55+FALSE
chr9136335345GA0.00490CACFD1+FALSE(TG)nSINE,Alu
chr633377511TC5.31992E-06.FALSE(TG)nSINE,Alu
chr1538780594CT0.00135RASGRP1-FALSE
chr3195243003AC0.00301PPP1R2-FALSE
chr1110049203GC0.00530.FALSE
chr19162932AT0.00635.FALSE
chr28996326CT0.00077MBOAT2-FALSE
chr1492629726TA0.00787CPSF2+FALSE
chr1075008965TC0.00017DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr7286402AG1.78989E-09FAM20C+FALSE
chr1150281017AG0.00057MRPS21+TRUEAluSzSINE,Alu
chr1169768080CA0.00980C1orf112+FALSE
chr1047221465TC0.00201.FALSEAluJbSINE,Alu
chr13730332TC6.29937E-05CEP104-TRUEAluSx3SINE,Alu
chr1113213009AT0.00556CAPZA1+FALSE
chr629704336GA0.00207.FALSEL1ME3ASINE,Alu
chr5115165591TC0.00407ATG12-TRUEAluSq2SINE,Alu
chr5172385223TC0.00796LOC100268168-FALSEAluSpSINE,Alu
chr146269545GA0.00378MAST2+FALSE
chr146830430GA0.00023NSUN4+FALSELTR108a_MamSINE,Alu
chr237328082TC0.00530.FALSE
chr111722350CA0.00355FBXO44+FALSEOldhAT1SINE,Alu
chr333893987AG0.00123PDCD6IP+FALSE
chr1077157784CT0.00027ZNF503-FALSE(T)nSINE,Alu
chr1227071525CT0.00013PSEN2+FALSE
chr2206986245TC0.00304.FALSEAluSzSINE,Alu
chr116889596TC0.00905NBPF1-TRUE
chr5162902516TC0.00226HMMR+FALSE
chr8145150065GC0.00585CYC1+FALSE
chr77918285GA0.00255UMAD1+FALSE
chr2101587455CT0.00178NPAS2+FALSE
chr7100739267GA0.00654.FALSEAluSxSINE,Alu
chr352289709GC4.88711E-11WDR82-FALSEMIRSINE,Alu
chr568738649AT0.00716.FALSE
chr353260620TG0.00069TKT-FALSE
chr140539203AT0.00179PPT1-FALSE
chr128865500TA0.00509RCC1+FALSE
chr136067886TC0.00786PSMB2-TRUEAluSzSINE,Alu
chr1726672363GA0.00599TNFAIP1+FALSE
chr1171561203TG0.00075PRRC2C+FALSE
chr830536583TC0.00031GSR-TRUEAluSpSINE,Alu
chr116910172GA0.00023NBPF1-FALSE
chr12133298121AG0.00026PGAM5+TRUEAluJoSINE,Alu
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr342266360TC0.00279TRAK1+FALSE
chr1205737659CT0.00024RAB29-FALSEAluSq2SINE,Alu
chr16257826TC0.00192RPL22-FALSE
chr618264355GA0.00872DEK-FALSE
chr1145369589TC0.00046NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr237330517TC0.00324.FALSEAluSq2SINE,Alu
chr1230416412CG0.00514GALNT2+FALSE
chr155316322AG0.00929DHCR24-FALSE
chr116160968CT0.00524FLJ37453-FALSE(T)nSINE,Alu
chr110042988AG3.32241E-06NMNAT1+TRUEAluScSINE,Alu
chr6150047370TC0.00154NUP43-TRUEAluScSINE,Alu
chr830643549GC0.00257PPP2CB-FALSE
chr2025427756AG0.00396GINS1+TRUEAluSzSINE,Alu
chr110520154TC0.00021.FALSEAluSxSINE,Alu
chr119499560TC0.00226UBR4-FALSE
chr3169807548TC0.00665PHC3-TRUEAluSx1SINE,Alu
chr237429627AG0.00330CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr356703746AC0.00017FAM208A-FALSE
chr1153963246GA6.32081E-05RPS27+FALSE
chr2132278176TG0.00291LOC150776+FALSE
chr1352327020GA0.00019WDFY2+FALSE
chr5175811093AG0.00730NOP16-FALSE
chr5180663940AG0.00331RACK1-FALSE
chr10865825CT0.00088LARP4B-FALSE
chr237331037TC0.00036.FALSEAluSx1SINE,Alu
chrX123045103AG0.00996XIAP+TRUEAluSpSINE,Alu
chr10119766673TG0.00082RAB11FIP2-FALSE
chr12133297934AG9.03426E-06PGAM5+TRUEAluJoSINE,Alu
chr5150578574AG0.00447CCDC69-FALSE
chr16694574GA0.00983THAP3,DNAJC11+,-FALSE
chr111141187CG0.00819EXOSC10-FALSE
chr116893721AC0.00043NBPF1-FALSE
chr153684924AG0.00913C1orf123-FALSEL1MA5ASINE,Alu
chr1778226862AC0.00590SLC26A11+FALSE
chr1221015760GA0.00758SLCO1B3+FALSE
chr116892135GA0.00182NBPF1-FALSE
chr3160213317TA0.00208KPNA4-FALSE
chr165692498TC0.00356AK4+FALSE(T)nSINE,Alu
chr1179326295AG0.00035SOAT1+TRUE
chr3196670082AT0.00261NCBP2-AS2+FALSE
chr312624763TC1.62214E-06MKRN2+FALSE
chr1160967890TC0.00871F11R-TRUEAluSpSINE,Alu
chr1911945685AG0.00016ZNF440+TRUEAluSpSINE,Alu
chr5125961647AG1.53189E-07PHAX+FALSEAluSz6SINE,Alu
chr674134075TC0.00018.FALSEAluYSINE,Alu
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr276672504AG2.97414E-06.FALSE7SKSINE,Alu
chr1765334828TC0.00160PSMD12-TRUEAluSqSINE,Alu
chr153289688AG0.00069ZYG11B+TRUEAluSzSINE,Alu
chr119542455TC0.00048LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1179989742GC0.00019CEP350+FALSE
chr1911257634TC0.00237SPC24-TRUEAluSpSINE,Alu
chr268402796CT0.00656PNO1+FALSE
chr3196080531TC0.00952UBXN7-TRUEAluSxSINE,Alu
chr1154128839GT0.00579TPM3-FALSE
chr2239259540GA0.00493CBX6-FALSE
chr110044367AG5.42058E-05NMNAT1+TRUEAluSx1SINE,Alu
chr143272842AT5.93810E-05SVBP-FALSE
chr191990450AT0.00405CDC7+FALSELFSINE_VertSINE,Alu
chr16283264TC0.00095ICMT-TRUEAluSx3SINE,Alu
chr1591044379TG0.00440IQGAP1+FALSE
chr146751319GA0.00085LRRC41-FALSE
chr1109475629AG0.00835GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr194335333GT0.00258DNTTIP2-FALSE
chr1145689537AG0.00341NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr153679878TC0.00348C1orf123-FALSE
chr124086794GT0.00028TCEB3+FALSE(T)nSINE,Alu
chr2242615532CA0.00603DTYMK-FALSE
chr9131071533TC0.00168TRUB2-TRUEFAMSINE,Alu
chr1109818158CT0.00628CELSR2+FALSE
chr1990280CT0.00243AGRN+FALSE
chr775958151GC0.00250YWHAG-FALSE
chr495586224AG0.00053PDLIM5+FALSE
chr236704035CA0.00012CRIM1+FALSE
chr398299365TG0.00133CPOX-FALSE
chr437953902TC0.00109TBC1D1+FALSE
chr488061645TA0.00049AFF1+FALSE(TATAT)nSINE,Alu
chr1116234083TA0.00477VANGL1+FALSE
chr642855200AG2.13337E-05RPL7L1+TRUEAluSpSINE,Alu
chr873958240GA0.00093TERF1+FALSE
chr133148691AG0.00207SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr2132481529CT0.00028C2orf27A+FALSE
chr232535836AG0.00163.FALSEAluJbSINE,Alu
chr775677504CT0.00768MDH2+FALSE
chr103208557AG0.00128PITRM1-FALSE
chr3148863151AG0.00062HPS3+FALSE
chr127205634TC0.00025.FALSEFLAM_ASINE,Alu
chr1214527252GA0.00830PTPN14-FALSEMADE2SINE,Alu
chr2178129405CT0.00295NFE2L2-FALSE(CGG)nSINE,Alu
chr17827697GC0.00760CAMTA1+FALSE
chr255459820CT0.00714RPS27A+FALSE
chr110520439TC0.00293.FALSEAluSx1SINE,Alu
chr417804740TC0.00015DCAF16-TRUEAluSxSINE,Alu
chr127204447TC0.00513.FALSEAluSg7SINE,Alu
chr232533707AG0.00395.FALSEAluSpSINE,Alu
chr1424884880TG0.00491NYNRIN+FALSE
chr9124103030GA0.00193STOM-FALSEAluSq2SINE,Alu
chr1145513051AG0.00269NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr3194369580CA0.00042LSG1-FALSE
chr116933583TC0.00050NBPF1-FALSEGA-richSINE,Alu
chr165692499CT0.00516AK4+FALSE(T)nSINE,Alu
chr393846831GA0.00547.FALSEAluSq2SINE,Alu
chr147716043AG0.00794STIL-FALSE
chr133149373AG0.00918SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1953914807AG4.44644E-06ZNF765+TRUEAluSpSINE,Alu
chr1109475572AG0.00096GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr138327700TC0.00510INPP5B-TRUEAluSx3SINE,Alu
chr3196079280TC0.00614.FALSEAluSxSINE,Alu
chr18212601CA0.00189USP14+FALSEAluSzSINE,Alu
chr270131584GA0.00366SNRNP27+FALSE
chr110517952CA0.00341.FALSE
chr1145441841AT0.00636NBPF20,NBPF10,TXNIP+FALSE
chr3122283290GC0.00029DTX3L,PARP9+,-FALSE
chr146075663AG0.00013NASP+TRUEAluSx4SINE,Alu
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu

Differential Expression Gene Analysis