Dataset Overview
RBP
TIAL1
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR450VQO
Platform
HiSeq
Pubmed ID
32252787
TIAL1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of TIAL1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
15.89
24.8
0.68892
4.06880E-06
9.42423E-06
A1CF
30.66
28.52
0.42642
8.24142E-06
1.84493E-05
A2M
2149.68
1919.71
-0.49156
7.01840E-08
1.95785E-07
A4GALT
0.85
0.64
-0.80805
0.03850
0.05384
AAAS
25.65
39.0
0.24115
0.01893
0.02783
AACS
15.28
8.27
-1.06627
1.54463E-24
1.29762E-23
AAED1
6.5
4.27
-0.90229
1.74826E-10
6.14679E-10
AAGAB
8.9
6.91
-0.41278
0.00135
0.00233
AAK1
2.42
3.84
0.65114
1.64517E-05
3.58470E-05
AAMDC
23.01
34.08
0.37724
0.01111
0.01694
Showing 1 to 10 of 10,129 entries
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Function Analysis of Target Genes of TIAL1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1BG
58863463_58863550_58862756_58863053_58863648_58863921
0.00112
-0.042
DataSet_01_36
View details
ABCA7
1057913_1058058_1057312_1057428_1058144_1058268
0.00269
-0.149
DataSet_01_36
View details
ABCA7
1057864_1058058_1057312_1057428_1058144_1058156
0.00731
-0.29
DataSet_01_36
View details
ABCC2
101576820_101576911_101572774_101572901_101577064_101577241
0.00017
-0.165
DataSet_01_36
View details
ABCC2
101576820_101576953_101572774_101572901_101577064_101577241
0.00086
-0.134
DataSet_01_36
View details
ABCC6
16249648_16249711_16248729_16248888_16251519_16251666
0.00465
-0.161
DataSet_01_36
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ABLIM1
116213137_116213242_116211382_116211430_116225456_116225586
0.00209
0.067
DataSet_01_36
View details
AC007246.3
39701667_39701768_39681437_39681506_39743554_39743682
0.00001
-0.381
DataSet_01_36
View details
AC027612.6
91817574_91817788_91805185_91806180_91842945_91843023
0.00609
-0.081
DataSet_01_36
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AC027612.6
91842945_91843023_91816786_91816979_91843393_91843404
0.00792
0.25
DataSet_01_36
View details
Showing 1 to 10 of 362 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52603747_52603882_52619601_52619745_52601621_52601752
0.00823
0.198
DataSet_01_36
View details
AASDH
57244313_57244630_57248642_57248763_57237616_57237809
0.00795
0.308
DataSet_01_36
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ABCD4
74759856_74759951_74761850_74761901_74759450_74759572
0.00656
0.176
DataSet_01_36
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ABLIM1
116207638_116207785_116211382_116211430_116205070_116205162
0.00630
0.145
DataSet_01_36
View details
ACADSB
124797262_124797363_124799981_124800188_124793871_124794031
0.00468
-0.099
DataSet_01_36
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ACOX1
73956295_73956456_73969705_73969866_73953539_73953647
0.00541
-0.138
DataSet_01_36
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ACSL3
223791734_223791907_223793579_223793654_223789173_223789313
0.00000
-0.071
DataSet_01_36
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ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00085
0.032
DataSet_01_36
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AFMID
76198783_76198832_76202026_76202131_76187050_76187141
0.00254
0.122
DataSet_01_36
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AFP
74310709_74310839_74313330_74313393_74309063_74309161
0.00000
-0.229
DataSet_01_36
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Showing 1 to 10 of 144 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSS2
33508334_33508563_33508334_33508512_33508808_33508969
0.00839
0.057
DataSet_01_36
View details
AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00696
0.068
DataSet_01_36
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APEX1
20923736_20923932_20923736_20923862_20924072_20924260
0.00031
0.04
DataSet_01_36
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APEX1
20923423_20923535_20923423_20923429_20923736_20923831
0.00957
-0.103
DataSet_01_36
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ARHGEF40
21555159_21555622_21555159_21555264_21556126_21556257
0.00379
0.145
DataSet_01_36
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AZI1
79171905_79172097_79171914_79172097_79171511_79171688
0.00316
-0.311
DataSet_01_36
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00049
0.08
DataSet_01_36
View details
CAPN2
223949282_223949441_223949282_223949319_223949887_223949953
0.00426
-0.042
DataSet_01_36
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CFB
31915732_31915971_31915732_31915858_31916150_31916289
0.00001
0.056
DataSet_01_36
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DHRS2
24113617_24113763_24113617_24113752_24114035_24114091
0.00226
-0.006
DataSet_01_36
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Showing 1 to 10 of 37 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ANKRD11
89383340_89383486_89383340_89383483_89484691_89484776
0.00353
0.183
DataSet_01_36
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AP1G2
24033254_24033430_24033254_24033368_24033541_24033597
0.00612
-0.105
DataSet_01_36
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APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00074
0.007
DataSet_01_36
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APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00095
0.02
DataSet_01_36
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ARSE
2878418_2878509_2878418_2878461_2882264_2882305
0.00068
-0.404
DataSet_01_36
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ATG9A
220075102_220075274_220075102_220075197_220075432_220075545
0.00003
0.186
DataSet_01_36
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ATG9A
220075102_220075311_220075102_220075197_220075432_220075545
0.00086
0.059
DataSet_01_36
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AUP1
74754374_74754520_74754374_74754490_74754597_74754717
0.00011
0.028
DataSet_01_36
View details
B4GALT3
161145597_161145885_161145597_161145864_161146223_161146369
0.00697
0.241
DataSet_01_36
View details
BRD2
32945036_32945347_32945218_32945347_32944338_32944713
0.00350
0.026
DataSet_01_36
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCB6
220075102_220075545_220075102_220075197_220075432_220075545
0.00001
0.103
DataSet_01_36
View details
ACAA1
38167316_38168191_38167316_38167372_38167652_38168191
0.00347
0.032
DataSet_01_36
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ACADVL
7123782_7123995_7123782_7123848_7123922_7123995
0.00224
0.064
DataSet_01_36
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ACADVL
7124084_7124377_7124084_7124149_7124242_7124377
0.00500
0.057
DataSet_01_36
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AFMID
76201576_76201819_76201576_76201599_76201683_76201819
0.00223
0.388
DataSet_01_36
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ANKZF1
220100731_220101373_220100731_220100817_220101043_220101373
0.00141
0.06
DataSet_01_36
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APEX1
20923736_20924260_20923736_20923862_20924072_20924260
0.00112
0.066
DataSet_01_36
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ATG9A
220081085_220081554_220081085_220081187_220081373_220081554
0.00460
0.115
DataSet_01_36
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ATXN2L
28846598_28847079_28846598_28846720_28846866_28847079
0.00026
0.282
DataSet_01_36
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ATXN2L
28847253_28848558_28847253_28847806_28848048_28848558
0.00334
0.076
DataSet_01_36
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
95658344
G
A
0.00100
TMEM56-RWDD3,LOC101928118,TMEM56
+,-
FALSE
chr1
20978451
T
C
0.00193
PINK1-AS,DDOST
-
TRUE
AluY
SINE,Alu
chr1
52306066
T
A
0.00154
NRDC
-
FALSE
(TCA)n
SINE,Alu
chr1
9160989
T
C
0.00092
.
FALSE
AluJb
SINE,Alu
chr1
116237273
A
G
0.00309
VANGL1
+
FALSE
chr1
115248084
C
T
0.00171
NRAS
-
FALSE
chr1
43897496
G
A
0.00481
SZT2
+
FALSE
chr1
179829584
T
C
0.00204
TOR1AIP2
-
TRUE
AluJr
SINE,Alu
chr1
26774224
A
G
0.00295
DHDDS
+
TRUE
AluSz6
SINE,Alu
chr1
108678732
T
C
0.00396
SLC25A24
-
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression