Dataset Overview
RBPIGF2BP3
Knock-MethodshRNA
RBP FamilyKH_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR302JQA
PlatformHiSeq
Pubmed ID32252787

IGF2BP3 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of IGF2BP3
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of IGF2BP3


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr174928967TG0.00921KIF1C+FALSEAluYSINE,Alu
chr240336210CT0.00828SLC8A1-AS1+FALSE
chr153291395AG0.00017ZYG11B+TRUEAluJrSINE,Alu
chr46675519AC0.00064LOC105374366-FALSE
chr131838550TA0.00595FABP3-FALSE
chr5141691252TC0.00596SPRY4-FALSE
chr12133298465AG5.98085E-08PGAM5+TRUEAluSpSINE,Alu
chr572876776CA0.00875UTP15+FALSE
chr3196660344TA0.00366SENP5+FALSE
chr7100031497TG0.00119MEPCE+FALSE
chr3195242996CA0.00136PPP1R2-FALSE
chr1146650337GT0.00589PDIA3P1+FALSE
chr119984100GC0.00037MINOS1-NBL1,NBL1+FALSE
chr126608021TA0.00069.FALSE
chr116933135GT2.86961E-06NBPF1-FALSEL1MC2SINE,Alu
chr238975953TA0.00432SRSF7-FALSE
chr4165999188TC0.00751TMEM192-TRUEFLAM_CSINE,Alu
chr4190864378TG0.00247FRG1+FALSEGA-richSINE,Alu
chr1951305797TC0.00397C19orf48-TRUEAluSgSINE,Alu
chr116891340TA0.00229NBPF1-FALSE
chr1541590839AG0.00344OIP5-AS1+TRUEAluSx1SINE,Alu
chr116889566TC0.00305NBPF1-TRUE
chrX77083614TC6.82446E-05MAGT1-TRUEAluSz6SINE,Alu
chr1680636806TG0.00926CDYL2-FALSE
chr345721990AG0.00779LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr119543282TC0.00228LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1100654813TC0.00352DBT-TRUEAluSzSINE,Alu
chr11252510TC1.62601E-05CPSF3L-TRUEAluSpSINE,Alu
chr1145375869GA0.00480NBPF20,NBPF10+FALSE
chr6143382538AT0.00145AIG1+FALSE
chr111141187CG0.00814EXOSC10-FALSE
chr1201845899GT1.72907E-05IPO9+FALSE
chr579923361TC0.00013DHFR-TRUEAluJrSINE,Alu
chr1228880466GA0.00216RHOU+FALSE
chr150906945CT0.00178FAF1-FALSE
chr5180682608CA0.00144CTC-338M12.4+FALSE
chr167874859TC0.00027SERBP1-TRUEAluSxSINE,Alu
chr1109239335GT0.00011PRPF38B+FALSE
chr162627128AG2.94675E-05PATJ+TRUEAluSxSINE,Alu
chr140435513CA0.00656MFSD2A+FALSE
chr126143725AT0.00116SEPN1+FALSEAluSxSINE,Alu
chr1144822920AT0.00040NBPF20,NBPF9+FALSE
chr1145512081AG0.00579NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1155403823AG0.00850ASH1L,POU5F1P4+,-FALSE
chr1542859452AG0.00123HAUS2+TRUEAluJbSINE,Alu
chr5176883676AT0.00456DBN1-FALSE(A)nSINE,Alu
chr153291434AG0.00108ZYG11B+TRUEAluJrSINE,Alu
chr1075008847TC0.00349DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr13546128AG0.00703TPRG1L+FALSEAluSzSINE,Alu
chr1144874760TC0.00267NBPF20,PDE4DIP+,-FALSE
chr2201774279TC9.55391E-05.FALSEAluSzSINE,Alu
chr1560678712GA0.00801ANXA2-FALSE
chr457326291AG0.00424PAICS+TRUEAluJrSINE,Alu
chr1201846675CT0.00146IPO9+FALSE
chr1298942665AG1.31028E-05TMPO+TRUEAluScSINE,Alu
chr128662057AG3.94650E-05MED18+TRUEAluSq2SINE,Alu
chr255462744CA0.00033RPS27A+FALSE
chr1143135063CA0.00397LOC102723769-FALSE
chr2128601464TC0.00161.FALSEAluJrSINE,Alu
chr574063154CG0.00255GFM2,NSA2+,-FALSE
chr342266349CT0.00942TRAK1+FALSE
chr9114696428GT0.00163UGCG+FALSE(TGTTTTT)nSINE,Alu
chr1145512166TA0.00823NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr3141164940CA0.00194ZBTB38+FALSE
chr11337736CG0.00012MRPL20-FALSE
chr63266908GA0.00974PSMG4+FALSE
chr146093409AC0.00383GPBP1L1-FALSEA-richSINE,Alu
chr7138764145TC0.00399ZC3HAV1-FALSE
chr1894375GA0.00052NOC2L-FALSE
chr117199303GA0.00062LOC440570+FALSE
chr119586520AG6.58771E-06MRTO4+TRUEAluSzSINE,Alu
chr115818065TC0.00372CASP9-TRUEAluJbSINE,Alu
chr786816663AG0.00103DMTF1+TRUEAluJrSINE,Alu
chr2191555984TA0.00171NAB1+FALSE
chr127107950GA0.00249ARID1A+FALSE
chr285132775CG7.25564E-06TMSB10+FALSE
chr136068052GT1.69686E-12PSMB2-FALSEL1ME4bSINE,Alu
chr1475202287TC0.00757FCF1+FALSEAluScSINE,Alu
chr1109818158CT4.51493E-05CELSR2+FALSE
chr133148225AG0.00031SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr110517623TC0.00664.FALSEAluSx1SINE,Alu
chr16279957AG0.00814RNF207+TRUEAluSpSINE,Alu
chr124288529TC0.00401PNRC2+FALSE
chr288913273GC0.00152EIF2AK3-FALSE
chr671298816AT0.00287.FALSE
chrM9988TC0.00011.FALSE
chr517276055TC0.00784BASP1+FALSE(TC)nSINE,Alu
chr1120164994CT0.00829ZNF697-FALSE
chr642856959AG6.63353E-07RPL7L1+TRUEAluSpSINE,Alu
chr11650797AG3.70820E-05CDK11B,CDK11A-FALSE
chr1144598755GA0.00743NBPF20+FALSE
chr1589739348AG0.00035ABHD2+FALSEMER5ASINE,Alu
chr9131093971AG0.00033COQ4+TRUEAluJoSINE,Alu
chr657034841GT0.00581ZNF451,LOC101927211+,-FALSE
chr1110551680CT0.00415AHCYL1+FALSE
chr1156084582TC0.00195LMNA+FALSE
chr1586288387CT0.00809AKAP13+FALSE
chr438945689CT1.01800E-05FAM114A1+FALSEAluScSINE,Alu
chr110517306TC0.00022.FALSEAluJrSINE,Alu
chr132687472GA0.00877TMEM234,EIF3I+,-FALSE
chr1100676277AG0.00135DBT-FALSE
chr1523313171AG0.00257HERC2P2-FALSE
chr19740894CT0.00097PIK3CD,PIK3CD-AS2+,-FALSEMLT1F1SINE,Alu
chr1220231254TC0.00376RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr146117185CT0.00714GPBP1L1-FALSE
chr8145159705GA0.00383MAF1+FALSE
chr128825418AG0.00046PHACTR4+TRUEAluSgSINE,Alu
chr1070742774AT0.00504DDX21+FALSE
chr1182993025CT0.00490LAMC1+FALSE
chr3179116220TC0.00343GNB4-TRUEAluSz6SINE,Alu
chr2232319593AC0.00348NCL-FALSEA-richSINE,Alu
chr238971644TG0.00239SRSF7-FALSE
chr643582795AG0.00087POLH+TRUEAluSx1SINE,Alu
chr1421929014TC0.00749RAB2B-TRUEAluSpSINE,Alu
chr1179326882AG1.03454E-05SOAT1+TRUEAluJoSINE,Alu
chr237329307TC0.00102.FALSEAluJr4SINE,Alu
chr147184539CT0.00425EFCAB14-FALSE
chr111181327CT0.00525MTOR-FALSE
chr133240842CT0.00446YARS-FALSE
chr191981317TA0.00539CSNK1G2+FALSE
chr1205686520AG0.00980NUCKS1-FALSE
chr2025427823AG0.00054GINS1+TRUEAluSzSINE,Alu
chr4128756628AG0.00011.FALSEAluSxSINE,Alu
chr2102484482GA0.00213MAP4K4+FALSE
chr129644328CT0.00014PTPRU+FALSE
chr1155106227AT0.00137EFNA1+FALSE
chr1208198625CT8.83580E-05PLXNA2-FALSE
chr9138798859CA0.00291CAMSAP1-FALSE
chr124022910GA0.00702RPL11+FALSE
chr119586455AG0.00772MRTO4+TRUEAluSzSINE,Alu
chr23592674CA0.00011RNASEH1-FALSE
chr366430372TA0.00300LRIG1-FALSE
chr2215674224GA9.97816E-05BARD1-FALSE
chr344791553TC1.10852E-07KIAA1143-TRUEAluJrSINE,Alu
chr552397314CT0.00249MOCS2-FALSE
chr237431639TC0.00160CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr1145100851AG0.00066NBPF20,SEC22B+FALSEAluSg4SINE,Alu
chr3172351006CG6.14326E-06NCEH1-FALSE
chr12123347005TA0.00268HIP1R+FALSE
chr2219100706AG0.00874ARPC2+TRUEAluSx1SINE,Alu
chr1060157509TG0.00296TFAM+FALSE
chr128662254AG0.00052MED18+TRUEAluSq2SINE,Alu
chr123631625AG0.00536HNRNPR-FALSEUCON44SINE,Alu
chr6160526904TG0.00027IGF2R+FALSE
chr110043053AG0.00042NMNAT1+TRUEAluScSINE,Alu
chr2191067766TC0.00034C2orf88+FALSE
chr110518688TC0.00154.FALSEAluSx1SINE,Alu
chr51574319TA0.00158SDHAP3-FALSE
chr178414310CA0.00067FUBP1-FALSE
chr1923542304TC2.38814E-05ZNF91-TRUEAluYSINE,Alu
chr72394991CT9.93448E-08EIF3B+FALSE
chr1168212509AG0.00765.FALSE
chr177165735AG0.00227.FALSE
chr1156011444TC0.00483UBQLN4-FALSE
chr1165764470TC0.00435EIF1AD-TRUEAluSz6SINE,Alu
chr4129796173GT1.40481E-05JADE1+FALSE
chr652365328TG0.00983TRAM2-FALSE(T)nSINE,Alu
chr186852621AG0.00930ODF2L-FALSE
chr285776590TC0.00950GGCX-TRUEAluSz6SINE,Alu
chr1590819471AG7.41591E-05.FALSEAluSxSINE,Alu
chr122161275GA0.00600HSPG2-FALSE
chr237327670TC0.00021.FALSE
chr110520383TC0.00401.FALSEAluSx1SINE,Alu
chr1565442112TC0.00529CLPX-TRUEAluSgSINE,Alu
chr5149829073AG0.00866RPS14-FALSE
chr6160100882TC0.00494SOD2-TRUEAluSzSINE,Alu
chr574669972CT0.00113COL4A3BP-FALSE
chr232535568AG0.00192.FALSEMER8SINE,Alu
chr2217366515AG0.00357.FALSEAluSzSINE,Alu
chr136067811TC0.00467PSMB2-TRUEAluSzSINE,Alu
chr1152186699TA0.00891HRNR-FALSE
chr255516940AC0.00389CCDC88A-FALSE(GA)nSINE,Alu
chr7100031511CT0.00490MEPCE+FALSE
chr1145512098AG0.00707NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr131905886CA0.00335SERINC2+FALSE
chr16283264TC0.00287ICMT-TRUEAluSx3SINE,Alu
chr1119693495AG0.00996LOC101929147+TRUEAluSxSINE,Alu
chr1179042692AG0.00707FAM20B+TRUEAluSx1SINE,Alu
chr110520145TC0.00590.FALSEAluSxSINE,Alu
chr285837797TC0.00050USP39,C2orf68+,-FALSEAluSxSINE,Alu
chr633268621TC0.00367.FALSEAluYSINE,Alu
chr1114940211GT0.00925TRIM33-FALSE(T)nSINE,Alu
chr5149013587GA0.00102ARHGEF37+FALSEL2dSINE,Alu
chr131532379AG0.00061PUM1-FALSE
chr345721989AG0.00713LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr333877626GA2.14228E-08PDCD6IP+FALSE
chr193297595GT0.00479RPL5+FALSE
chr72274209TC0.00578MRM2-FALSEAluJrSINE,Alu
chr144088112GT0.00822PTPRF+FALSE(T)nSINE,Alu
chr124288530AT0.00915PNRC2+FALSE
chr775958149AC0.00050YWHAG-FALSE
chr1743364293CG0.00144MAP3K14-FALSE
chr237331525TC0.00140.FALSEAluJbSINE,Alu
chr7128142833AG6.82570E-05METTL2B+TRUEAluSx1SINE,Alu
chr1212967264CG0.00781DDX47+FALSE
chr3156258295TC0.00096SSR3-TRUEAluYk3SINE,Alu
chr2114356360GA0.00520WASH2P+FALSE
chr232535692AG0.00236.FALSEAluJbSINE,Alu
chr126158907AG0.00061MTFR1L,AUNIP+,-FALSE
chr1183218871GT0.00025NMNAT2-FALSE
chr1144833386AG0.00325NBPF20+FALSEL1MEcSINE,Alu
chr11595586TC0.00051CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr9115447518TC0.00084INIP-TRUEAluJbSINE,Alu
chrX24095285AG0.00135EIF2S3+TRUEAluSxSINE,Alu
chr317201882CT0.00259TBC1D5-FALSE
chr425236017TC0.00291PI4K2B+FALSE
chr110003320GA0.00168LZIC,NMNAT1+,-FALSE
chr136923643GC0.00409MRPS15-FALSE
chr145975345AG0.00127MMACHC+TRUEAluSg7SINE,Alu
chr1061548856TC0.00067CCDC6-FALSE
chr136067817TC0.00120PSMB2-TRUEAluSzSINE,Alu
chr1788795TG0.00333LINC01128+FALSECharlie19aSINE,Alu
chr16583457TC9.96562E-05NOL9-TRUEAluSqSINE,Alu
chr174930749AG0.00025KIF1C+TRUEFLAM_ASINE,Alu
chr239009427AG0.00673.FALSEAluSx3SINE,Alu
chr194995653AC0.00035F3-FALSEAluSxSINE,Alu
chr16354955GA0.00282ACOT7-FALSE
chr1629454295TC0.00019SMG1P6,BOLA2-SMG1P6-TRUETigger4aSINE,Alu
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr133071096AG0.00139ZBTB8A+TRUEAluSx1SINE,Alu
chr1331033325CA0.00792HMGB1-FALSE
chr1942731991AG0.00598.FALSEAluJrSINE,Alu
chr125688276AG0.00187TMEM50A+FALSE
chr347628808AT0.00792SMARCC1-FALSE
chr271214819AT0.00346TEX261-FALSE
chr1610623688TC0.00766EMP2-TRUEAluSpSINE,Alu
chr12335348CT0.00018RER1+FALSE
chr145244421GA0.00925.FALSE
chr110517659TC0.00516.FALSEAluSx1SINE,Alu
chr1095163809GT0.00453MYOF-FALSE
chr112628188TC3.43513E-08DHRS3-FALSE
chr2206862015GA0.00026INO80D-FALSE
chr2128949255AG0.00063UGGT1+TRUEAluSgSINE,Alu
chr1326539AG0.00450.FALSE
chr146830110AG0.00283NSUN4+TRUEAluSx1SINE,Alu
chr1590819472AG0.00068.FALSEAluSxSINE,Alu
chr1150548883AC0.00255MCL1-FALSE
chr2102484489AC0.00281MAP4K4+FALSE
chr119542679TC0.00584LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr99442082TG0.00052PTPRD-FALSE7SLRNASINE,Alu
chr193827995CT0.00714DR1+FALSE
chr1957816349AG8.96695E-06.FALSEAluYSINE,Alu
chr144423703CT1.17684E-14IPO13+FALSE
chr226617209AG5.06124E-05EPT1+FALSEAluSzSINE,Alu
chr1179042905AG0.00034FAM20B+TRUE
chr132742441GA2.83845E-11LCK+FALSE
chr285772404CA0.00015GGCX-FALSE
chr1145284883AG0.00329NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr1145369556AG0.00061NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr128859267AC2.52971E-07RCC1+FALSE
chr1773940167TC0.00035ACOX1-TRUEAluJbSINE,Alu
chr5109204057TA0.00614MAN2A1+FALSE
chr237330612TC0.00136.FALSEAluSq2SINE,Alu
chr2112252630AC0.00040MIR4435-2HG-FALSE

Differential Expression Gene Analysis