Dataset Overview
RBP
IGF2BP2
Knock-Method
shRNA
RBP Family
KH_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR478FJK
Platform
HiSeq
Pubmed ID
32252787
IGF2BP2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of IGF2BP2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
40.38
33.02
-0.41387
3.80390E-07
1.08225E-06
A1CF
29.02
37.45
0.45102
1.80773E-10
6.97851E-10
A2M
2827.98
2284.53
-0.42580
5.78297E-10
2.14239E-09
AAAS
21.26
20.3
-0.27388
0.00126
0.00235
AACS
17.52
17.45
-0.15219
0.04380
0.06303
AADAT
2.45
3.71
0.35087
0.01759
0.02720
AAGAB
4.83
11.84
1.33605
3.07626E-41
5.95877E-40
AAK1
1.2
3.72
1.52216
2.69958E-24
2.52698E-23
AAMP
124.44
94.7
-0.44550
3.51660E-10
1.32864E-09
AARS
51.81
62.36
0.13982
0.03656
0.05339
Showing 1 to 10 of 9,222 entries
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Function Analysis of Target Genes of IGF2BP2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52642232_52642465_52619601_52619745_52645340_52645435
0.00023
0.113
DataSet_01_374
View details
ABCC2
101579184_101579299_101578845_101579026_101590063_101590190
0.00031
-0.044
DataSet_01_374
View details
ABCC2
101601723_101601850_101595874_101596047_101603555_101603657
0.00853
-0.034
DataSet_01_374
View details
ADNP
49545187_49545362_49520425_49520538_49547362_49547750
0.00550
-0.214
DataSet_01_374
View details
AFP
74310709_74310839_74309063_74309161_74315051_74315184
0.00071
-0.016
DataSet_01_374
View details
AFP
74313178_74313393_74309067_74309161_74315051_74315184
0.00435
-0.013
DataSet_01_374
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AFP
74320952_74321007_74319481_74319614_74321347_74321891
0.00475
-0.005
DataSet_01_374
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AGAP1
236839408_236839567_236817381_236817550_236877105_236877267
0.00993
-0.092
DataSet_01_374
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AHSG
186336324_186336426_186334972_186335139_186338374_186339089
0.00000
-0.04
DataSet_01_374
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AHSG
186337645_186337729_186334933_186335139_186338374_186339089
0.00000
-0.027
DataSet_01_374
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Showing 1 to 10 of 405 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADS
121175639_121175791_121175851_121175991_121175158_121175270
0.00884
-0.198
DataSet_01_374
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ACP1
272036_272150_272191_272305_271865_271939
0.00000
0.129
DataSet_01_374
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ACP1
272036_272150_272191_272305_271865_271939
0.00042
0.089
DataSet_01_374
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ACSM3
20690479_20690771_20760586_20760690_20685831_20686144
0.00518
0.2
DataSet_01_374
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AHSG
186336079_186336280_186337645_186337729_186334975_186335139
0.00000
0.021
DataSet_01_374
View details
AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00000
-0.306
DataSet_01_374
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AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00000
0.014
DataSet_01_374
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00000
0.044
DataSet_01_374
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AHSG
186336300_186336426_186337645_186337729_186334975_186335139
0.00001
0.021
DataSet_01_374
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AHSG
186334933_186335139_186337645_186337729_186334231_186334316
0.00032
0.498
DataSet_01_374
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Showing 1 to 10 of 129 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSS2
33509773_33509918_33509773_33509795_33511125_33511234
0.00919
-0.212
DataSet_01_374
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ALB
74279136_74279307_74279136_74279299_74280751_74280884
0.00145
-0.014
DataSet_01_374
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AP2M1
183900544_183900743_183900544_183900656_183901269_183901450
0.00006
0.162
DataSet_01_374
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APOA1
116708234_116708325_116708274_116708325_116708060_116708123
0.00646
0.124
DataSet_01_374
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ATG4B
242610726_242610966_242610726_242610820_242611605_242613272
0.00753
0.443
DataSet_01_374
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ATP5G1
46970770_46970954_46970770_46970818_46971733_46971811
0.00001
0.046
DataSet_01_374
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BPIFB2
31608133_31608254_31608133_31608201_31608347_31608393
0.00000
0.094
DataSet_01_374
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00608
0.096
DataSet_01_374
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C21orf33
45557058_45557259_45557058_45557178_45560131_45560224
0.00328
0.081
DataSet_01_374
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CCDC57
80064050_80064251_80064145_80064251_80059335_80059742
0.00532
0.044
DataSet_01_374
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Showing 1 to 10 of 51 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7127798_7127871_7127802_7127871_7127639_7127712
0.00010
-0.073
DataSet_01_374
View details
ACLY
40061774_40061911_40061774_40061891_40062780_40062981
0.00779
-0.272
DataSet_01_374
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AD000671.6
36235526_36235639_36235526_36235593_36236025_36236088
0.00700
0.339
DataSet_01_374
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AP1G2
24031170_24031411_24031170_24031275_24031496_24031624
0.00146
-0.083
DataSet_01_374
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APOA1
116707794_116707865_116707794_116707847_116708060_116708141
0.00000
-0.167
DataSet_01_374
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APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00043
-0.013
DataSet_01_374
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APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00308
-0.026
DataSet_01_374
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APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00905
-0.009
DataSet_01_374
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ATP6V1G2-DDX39B
31508258_31508423_31508258_31508311_31509726_31509925
0.00030
-0.18
DataSet_01_374
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AUP1
74754067_74754267_74754067_74754186_74754374_74754446
0.00339
-0.027
DataSet_01_374
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00003
0.098
DataSet_01_374
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ACAA1
38167316_38168191_38167316_38167372_38167652_38168191
0.00042
0.045
DataSet_01_374
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ACAA1
38167316_38168191_38167316_38167372_38168000_38168191
0.00690
0.236
DataSet_01_374
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ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00580
0.019
DataSet_01_374
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ACADVL
7127639_7127871_7127639_7127712_7127802_7127871
0.00710
-0.081
DataSet_01_374
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ACADVL
7123782_7123995_7123782_7123848_7123922_7123995
0.00998
0.05
DataSet_01_374
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00000
0.019
DataSet_01_374
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ACTB
5567634_5568350_5567634_5567816_5567911_5568350
0.00347
0.007
DataSet_01_374
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APEH
49713488_49713948_49713488_49713652_49713810_49713948
0.00901
0.021
DataSet_01_374
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APOA1
116708060_116708330_116708060_116708123_116708234_116708330
0.00111
-0.107
DataSet_01_374
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
9160989
T
C
0.00609
.
FALSE
AluJb
SINE,Alu
chr1
100440553
A
G
0.00553
SLC35A3
+
TRUE
AluJb
SINE,Alu
chr1
218617066
A
T
0.00036
TGFB2-OT1,TGFB2
+
FALSE
chr1
162497738
G
C
0.00390
UHMK1
+
FALSE
chr1
168220364
A
G
6.18665E-05
.
FALSE
AluSz6
SINE,Alu
chr1
46032974
T
C
0.00196
AKR1A1
+
FALSE
chr1
1594977
T
C
7.82676E-05
CDK11B,SLC35E2B
-
TRUE
AluSg
SINE,Alu
chr1
65879488
A
C
0.00560
DNAJC6
+
FALSE
chr1
86816600
A
G
0.00830
ODF2L
-
FALSE
L1PA7
SINE,Alu
chr1
320211
A
G
6.69717E-05
.
FALSE
AluJo
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression