Dataset Overview
RBPPNPT1
Knock-MethodshRNA
RBP FamilyRNase_PH
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR191VWK
PlatformHiSeq
Pubmed ID32252787

PNPT1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PNPT1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PNPT1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr848889672AG0.00091MCM4+TRUEAluSx3SINE,Alu
chr135251229GA0.00516GJB3+FALSE
chr11251841TC0.00915CPSF3L-TRUEAluSq2SINE,Alu
chr116933631GA0.00442NBPF1-FALSEGA-richSINE,Alu
chr899053985TG4.76792E-05RPL30-FALSE
chr7137561084GA0.00194CREB3L2-FALSE(GT)nSINE,Alu
chr265432447CT0.00486.FALSE
chr356763328TC0.00546ARHGEF3-FALSE
chr312940377GT0.00878IQSEC1-FALSE
chr1061548859AC0.00011CCDC6-FALSE
chr193827995CT0.00236DR1+FALSE
chr799017241CA0.00721PTCD1,ATP5J2-PTCD1-FALSE
chr2187544223TG0.00254ITGAV+FALSE
chr2202031506AG0.00508CFLAR+TRUESVA_ASINE,Alu
chr11597423CT1.10134E-13CDK11B,SLC35E2B-FALSE
chr1551294995GA0.00268AP4E1+FALSE
chr1745219755GT0.00592CDC27-FALSE
chr1145293469GC0.00888NBPF20,NBPF10+FALSE
chr3158320703CA0.00841MLF1+FALSE
chr2218572729AG0.00228PEX26+TRUEAluYf1SINE,Alu
chr229135468CG0.00217WDR43+FALSE
chr143167907TC0.00072YBX1+FALSE
chr1101443431CT0.00013SLC30A7+FALSEAluSq2SINE,Alu
chr119542621TC1.78455E-05LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr314175262TC3.06250E-10TMEM43+FALSE
chr348787219AG0.00024PRKAR2A-FALSE
chr110517314TC0.00073.FALSEAluJrSINE,Alu
chr1919793168AG0.00481ZNF101+TRUEAluSzSINE,Alu
chr2191555980TA0.00913NAB1+FALSE
chr1156495520TA0.00048IQGAP3-FALSE
chr237330503TC0.00177.FALSEAluSq2SINE,Alu
chr1110136329GT0.00993GNAI3+FALSE
chr1942375586AG0.00404.FALSEAluSxSINE,Alu
chr16282426TC0.00513ICMT-TRUEAluSzSINE,Alu
chr1911256725TC0.00096SPC24-TRUEAluJr4SINE,Alu
chr146075612AG0.00153NASP+TRUEAluSx4SINE,Alu
chr1118066724AT0.00979MAN1A2+FALSE
chr110520145TC0.00590.FALSEAluSxSINE,Alu
chr1204524400AG0.00029MDM4+TRUEAluYSINE,Alu
chr11650797AG3.70820E-05CDK11B,CDK11A-FALSE
chr118707397TA0.00046RPL27A+FALSE
chr11246979GT0.00168PUSL1,CPSF3L+,-FALSE
chr128826128AG0.00060PHACTR4+TRUEAluJbSINE,Alu
chr237431563AG0.00993CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr1226171340TC0.00462SDE2-TRUEBC200SINE,Alu
chr1121133392TC0.00651SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr10117823568TA0.00483GFRA1-FALSE(ATC)nSINE,Alu
chr1610625266TC0.00587EMP2-TRUEAluSxSINE,Alu
chr125890189AG0.00961LDLRAP1+FALSE
chr6150045919TC0.00206NUP43-TRUEAluSqSINE,Alu
chr120976078TC0.00064PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr117733270TA0.00088RCC2-FALSE
chr42841551AG0.00258SH3BP2+TRUEAluJrSINE,Alu
chr123409538GA0.00292KDM1A+FALSE
chr2208619675AG0.00012CCNYL1+TRUEAluJbSINE,Alu
chr3156258230TC0.00176SSR3-TRUEAluYk3SINE,Alu
chr310290508CT0.00682TATDN2+FALSE
chr2113289701TG0.00994TTL+FALSE
chr399886662GA0.00011CMSS1+FALSE
chr755433884AC0.00271LANCL2+FALSE
chr299813003AG0.00370MRPL30+TRUEAluJbSINE,Alu
chr12125512173AG0.00285.FALSEAluSx1SINE,Alu
chr16282371TC0.00897ICMT-TRUEAluSzSINE,Alu
chr2158170017TC0.00662GALNT5+FALSE
chr4169910101CT0.00026CBR4-FALSE
chr2147676711GA0.00316MCM3AP-FALSE
chr12133389998TC0.00829GOLGA3-FALSE
chr11419768AG0.00189ATAD3B+TRUEAluYk2SINE,Alu
chr1155403823AG0.00850ASH1L,POU5F1P4+,-FALSE
chr1145273345TC0.00640NBPF20,NOTCH2NL+FALSE
chr1179041705AT0.00068FAM20B+FALSE
chr1245017464TA0.00624HNRNPU,SNORA100-FALSE
chr16283264TC0.00073ICMT-TRUEAluSx3SINE,Alu
chr5149363414AG0.00503SLC26A2+TRUEAluJrSINE,Alu
chr138279987TC0.00980MTF1-FALSE
chr1143189076GA0.00048LOC102723769-FALSE
chr192148839TC0.00259TGFBR3-FALSE
chr146076529AG0.00336NASP+TRUEAluSxSINE,Alu
chr1569492TC0.00336.FALSE
chr128836973AG0.00289SNHG3,RCC1+TRUEAluScSINE,Alu
chr3126755134CT0.00920PLXNA1+FALSE
chr7143003525TA0.00064CASP2+FALSEAluYSINE,Alu
chr1179042905AG0.00034FAM20B+TRUE
chr1210416438CA0.00085SERTAD4+FALSE
chr517276080AC0.00298BASP1+FALSE(TC)nSINE,Alu
chr1145512078AG0.00907NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr11252468TC0.00096CPSF3L-TRUEAluJrSINE,Alu
chr1681064543AG0.00066CENPN+TRUEAluSgSINE,Alu
chr314986104TC0.00307FGD5-AS1-TRUEFLAM_CSINE,Alu
chr8124262075GT7.79989E-05ZHX1-C8orf76,ZHX1-FALSE
chr1214529740TC0.00375PTPN14-TRUE
chr540830064TC0.00554.FALSEAluSpSINE,Alu
chr237431485AG0.00339CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr928403GT1.21037E-06WASH1-FALSEMIRSINE,Alu
chr1145695329AG0.00400NBPF20,NBPF10+FALSEAluSzSINE,Alu
chr274442550AT0.00826.FALSE
chr473922981TC0.00491COX18-TRUEAluSzSINE,Alu
chr110519982TC0.00129.FALSEAluJrSINE,Alu
chr19328120AG0.00024H6PD+TRUEAluJrSINE,Alu
chr357551513AG0.00037PDE12+TRUEAluScSINE,Alu
chr131902343TC1.48709E-05SERINC2+FALSE
chr119585917TA0.00308MRTO4+FALSEAluJrSINE,Alu
chrX119572534CA0.00387LAMP2-FALSE
chr1220231946TC0.00439RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr11650787TC0.00071CDK11B,CDK11A-FALSE
chr1184675814GA0.00048EDEM3-FALSE
chr146076467AG0.00475NASP+TRUEAluSxSINE,Alu
chr1145281656AT0.00202NBPF20,NOTCH2NL+FALSE
chr3195243006CA0.00982PPP1R2-FALSE
chr6150047376TC0.00306NUP43-TRUEAluScSINE,Alu
chr110042955AG0.00131NMNAT1+TRUEAluScSINE,Alu
chr344791355TC0.00468KIAA1143-TRUEAluJrSINE,Alu
chr1116235179GT0.00187VANGL1+FALSE
chr1942375611AG0.00426.FALSEAluSxSINE,Alu
chr136522460AG0.00407.FALSEAluScSINE,Alu
chr340578933AG0.00947ZNF621+TRUEAluJrSINE,Alu
chr146828653TA0.00920NSUN4+FALSE
chr1958375157AG0.00408ZNF587+TRUEAluSx4SINE,Alu
chr237506939AG0.00119PRKD3-FALSE
chr457326186AG0.00203PAICS+TRUEAluJrSINE,Alu
chr224223353AG0.00083UBXN2A+TRUEAluScSINE,Alu
chr1109856085GA0.00684SORT1-FALSE
chr1168218574AG0.00148.FALSEAluSzSINE,Alu
chr231557839GT0.00145XDH-FALSEAluJrSINE,Alu
chr9136335345GA0.00490CACFD1+FALSE(TG)nSINE,Alu
chr13546269CA0.00260TPRG1L+FALSEAluSzSINE,Alu
chr1742113064AG0.00014LSM12-FALSE(A)nSINE,Alu
chr7128143797AG4.50405E-06.FALSEAluSq2SINE,Alu
chr116890500GA0.00030NBPF1-FALSE
chr12125511961AG1.08093E-06THRIL-FALSEAluSx1SINE,Alu
chr468484330GA0.00131UBA6-FALSE
chr340578815AG0.00041ZNF621+FALSEAluJrSINE,Alu
chr1121134245CT0.00174SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSE(TTTCCT)nSINE,Alu
chr153359745AG0.00661ZYG11A+TRUEAluSx4SINE,Alu
chr120976589CT0.00125PINK1,PINK1-AS+,-FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr121602602AG8.31525E-05ERC1+FALSEAluSxSINE,Alu
chr136068295TC0.00910PSMB2-TRUEAluScSINE,Alu
chr1610624993TC1.49189E-05EMP2-TRUEAluSx3SINE,Alu
chr1051374391CG0.00028TIMM23B+FALSE
chr11288481CA0.00013MXRA8-FALSE
chr39821914CT7.78954E-06TADA3-FALSE
chr1214524576TC0.00337PTPN14-TRUEAluSgSINE,Alu
chr1628296456TC0.00772.FALSEAluJbSINE,Alu
chr1610623544TC2.29348E-06EMP2-TRUEAluSpSINE,Alu
chr12133298053AG7.95391E-05PGAM5+TRUEAluJoSINE,Alu
chr145504720GC0.00759ZSWIM5-FALSE
chr1160967855TC0.00042F11R-TRUEAluSpSINE,Alu
chr116889503TC0.00130NBPF1-FALSEL1MC4SINE,Alu
chr812880299AG1.70760E-05KIAA1456+TRUEAluJoSINE,Alu
chr1523282589AG0.00291HERC2P2-FALSE
chr3125033835TG0.00385ZNF148-FALSEAluJbSINE,Alu
chr1200522059AT0.00163KIF14-FALSEAluSgSINE,Alu
chr1251324122AG0.00226METTL7A+TRUEAluSq2SINE,Alu
chr193298756TC0.00264FAM69A,RPL5+,-FALSEMER5CSINE,Alu
chr1935741552CT0.00165LSR+FALSE
chrX123046302AG0.00649XIAP+TRUEAluJbSINE,Alu
chr155207982CA0.00063MROH7-TTC4,TTC4+FALSE
chr1152187945CT9.69718E-05HRNR-FALSE(GCCAGA)nSINE,Alu
chr1419685015CG0.00069DUXAP10+FALSE
chr116842064AC0.00079.FALSEMER41ESINE,Alu
chr1145513113AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr388104073GC0.00887CGGBP1-FALSE
chr237429677AG0.00279CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr1963697GA0.00742WASH5P-FALSE
chr29630231CT0.00895ADAM17-FALSE
chr1168523337TC0.00016CPT1A-TRUEAluSqSINE,Alu
chr1206566195CT0.00334SRGAP2+FALSE
chr271214819AT0.00346TEX261-FALSE
chr1150771703TC0.00500CTSK-FALSE
chr296915238TC2.48142E-05.FALSEAluJrSINE,Alu
chr5122359494GC0.00043PPIC-FALSE
chr19161365TC4.68504E-05.FALSEAluSxSINE,Alu
chr7300181GA2.39021E-07FAM20C+FALSE
chr1749042206TC0.00030SPAG9-TRUEAluJbSINE,Alu
chr7158536267TC0.00298ESYT2-FALSE
chr8145159718GC0.00409MAF1+FALSE
chr830536544TC5.33169E-07GSR-TRUEAluSpSINE,Alu
chr127992825GA0.00192IFI6-FALSE
chr3196670087GA4.07177E-06NCBP2-AS2+FALSE
chr1212459257AG0.00068PPP2R5A+FALSE
chr16354955GA0.00090ACOT7-FALSE
chr189225976TC0.00586PKN2+FALSE
chr286251151TC0.00882.FALSEAluSxSINE,Alu
chr1182356399AG0.00740GLUL-FALSE
chr138478446CG4.10892E-09UTP11+FALSE
chr476568481AT0.00744G3BP2-FALSE(TA)nSINE,Alu
chr1911257634TC0.00823SPC24-TRUEAluSpSINE,Alu
chr124798498CT0.00131NIPAL3+FALSE
chr261416407GT0.00041USP34-FALSEAluSc8SINE,Alu
chr3181430334GA0.00305SOX2-OT,SOX2+FALSE
chr1145512950AG0.00996NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr122357435AC0.00454LINC00339+FALSE
chr333909024AT0.00134PDCD6IP+FALSE
chr1220323448CT0.00986RAB3GAP2-FALSE
chr636894339GA0.00650C6orf89+FALSEGA-richSINE,Alu
chr439550967TC2.19217E-06UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1146400122CG0.00190NBPF20,NBPF10,NBPF25P,NBPF12+FALSE
chr110521172TC1.01590E-06DFFA-TRUEAluYSINE,Alu
chr268402796CT0.00656PNO1+FALSE
chr3141879765TC0.00212GK5-TRUEAluJrSINE,Alu
chr830536544TC0.00122GSR-TRUEAluSpSINE,Alu
chr237331736TC0.00165.FALSEAluJbSINE,Alu
chr7120740103GT0.00601CPED1+FALSE

Differential Expression Gene Analysis