Dataset Overview
RBPMAK16
Knock-MethodshRNA
RBP FamilyRibosomal_L28e
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR517JHY
PlatformHiSeq
Pubmed ID32252787

MAK16 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of MAK16
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of MAK16


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr116918502AG0.00437NBPF1-FALSE
chr141326886CG0.00085CITED4-FALSE
chr299812311AG0.00016MRPL30+TRUEAluSxSINE,Alu
chr1453242354TC3.85910E-06GNPNAT1-TRUEAluJoSINE,Alu
chr1179814457AC0.00152TOR1AIP2-FALSE
chr116889414TC0.00384NBPF1-TRUEL1MC4SINE,Alu
chr1200522059AT0.00163KIF14-FALSEAluSgSINE,Alu
chr7137561076AG0.00488CREB3L2-FALSE
chr1153917621GC0.00020DENND4B-FALSE
chr4165998078TC0.00567TMEM192-TRUEAluSxSINE,Alu
chr6107113953CG0.00300QRSL1+FALSEAluSgSINE,Alu
chr330047174AT0.00556RBMS3+FALSE
chr357913810GA0.00477SLMAP+FALSE
chr1176176230GA0.00168RFWD2-FALSE
chr124798498CT0.00131NIPAL3+FALSE
chr1145281408CT9.69497E-05NBPF20,NOTCH2NL+FALSE
chr631324643GC5.95617E-06.FALSE
chr652860743TG1.89710E-05.FALSE7SKSINE,Alu
chr1234561498TC2.33971E-05TARBP1-FALSE
chr2170103351GT0.00139LRP2-FALSE
chr116929148GA0.00037NBPF1-FALSELTR16B2SINE,Alu
chr345960558CT6.37727E-08FYCO1-FALSE
chr1160112340AG0.00374ATP1A2+TRUEAluSx3SINE,Alu
chr1118066724AT0.00979MAN1A2+FALSE
chr237329307TC0.00102.FALSEAluJr4SINE,Alu
chr3119212015GA0.00024POGLUT1+FALSE
chr76442891GA0.00134RAC1+FALSE
chr132661600CT0.00235TXLNA+FALSE(T)nSINE,Alu
chr119585917TA0.00308MRTO4+FALSEAluJrSINE,Alu
chr19163290TC0.00130.FALSEAluSpSINE,Alu
chr1674698531TC0.00702RFWD3-TRUEAluSx3SINE,Alu
chr192148839TC0.00259TGFBR3-FALSE
chr116889633TC0.00217NBPF1-TRUE
chr116935130CT0.00155NBPF1-FALSE
chr791742141TA0.00620CYP51A1-FALSEAluSx3SINE,Alu
chr352288956AT0.00042WDR82-FALSE
chr4101947014GC0.00140PPP3CA-FALSE
chr116933631GA0.00927NBPF1-FALSEGA-richSINE,Alu
chr345125417GA0.00024CDCP1-FALSEAluJbSINE,Alu
chr274442550AT0.00826.FALSE
chr1089004545TC0.00192NUTM2A-AS1-FALSEMSTASINE,Alu
chr144463185TG0.00969SLC6A9-FALSE
chr116892275CT0.00087NBPF1-FALSE
chr116890320TC0.00045NBPF1-FALSE
chr111780004GT0.00216DRAXIN+FALSE
chr2196600548GT0.00036SLC39A10+FALSE
chr178029102GA0.00086ZZZ3-FALSE
chr1749042388TC2.65954E-10SPAG9-TRUEAluJbSINE,Alu
chr110042987AG0.00488NMNAT1+TRUEAluScSINE,Alu
chr110520378TC0.00115.FALSEAluSx1SINE,Alu
chr1180082703CA2.04280E-05CEP350+FALSE
chr1755752444CT0.00000MSI2+FALSE
chr194428790AT0.00000CHAF1A+FALSE
chr1225678219TC0.00080ENAH-TRUEAluSxSINE,Alu
chr1186281696TG0.00564PRG4,TPR+,-FALSE
chr11686040GT0.00543NADK-FALSE
chr116933623GA0.00789NBPF1-FALSEGA-richSINE,Alu
chr11344998AG0.00062.FALSEAluSgSINE,Alu
chr2183642878GA0.00373DNAJC10+FALSE
chr1953155567TC0.00137ZNF83-TRUEAluSgSINE,Alu
chr121602602AG8.31525E-05ERC1+FALSEAluSxSINE,Alu
chr120982631GA0.00133DDOST-FALSE
chr4155457601TC0.00423PLRG1-FALSE
chr1168213413TC0.00733.FALSEAluSx1SINE,Alu
chr1229439639TA0.00276RAB4A+FALSE
chr638140503CT0.00065BTBD9-FALSE
chr3196612193AG7.35500E-07SENP5+FALSE
chr744917291TC0.00019PURB-TRUEAluSzSINE,Alu
chr299812450AG7.07141E-05MRPL30+TRUEAluSxSINE,Alu
chr117730CA0.00256WASH7P-FALSE
chr5112312528TC0.00827DCP2+FALSE
chr1939982631AG0.00316TIMM50+TRUEAluJrSINE,Alu
chr1468117864AT0.00744ARG2+FALSE
chr23622912GT0.00000RPS7+FALSE
chr110519951TC0.00672.FALSEAluJrSINE,Alu
chr116913677TC0.00638NBPF1-FALSE
chr42940085TC0.00801NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr340503561AT0.00012RPL14+FALSE
chr5125961810AG3.92353E-06PHAX+TRUEFLAM_CSINE,Alu
chr117320251GA0.00367ATP13A2-FALSE
chr4120219638AT0.00970C4orf3-FALSE
chr2206987725TC0.00108.FALSEAluJbSINE,Alu
chr1154554945AG0.00877ADAR-FALSE
chr1150704413TC0.00236CTSS-TRUEAluJoSINE,Alu
chr16314743CT6.72719E-05GPR153-FALSE
chr5134236311AT0.00025TXNDC15+FALSEAluSqSINE,Alu
chr634213986TA0.00262HMGA1+FALSE
chr1145284883AG0.00329NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr775958147TA0.00917YWHAG-FALSE
chr3196670090GA6.78352E-09NCBP2-AS2+FALSE
chr125889571GA0.00344LDLRAP1+FALSE
chr1145512950AG2.03454E-08NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr339449137TC0.00000RPSA+FALSE
chr12434523TC0.00064PLCH2+FALSE
chr1681744038TC6.34278E-05CMIP+FALSE(CCGC)nSINE,Alu
chr6149912307AG0.00026.FALSEAluScSINE,Alu
chr439552022TC0.00015UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr146076543AG0.00156NASP+TRUEAluSxSINE,Alu
chr1212910930GA2.01027E-05NSL1-FALSE
chr1113001409CT2.24539E-06CTTNBP2NL+FALSEAluJrSINE,Alu
chr133149399AG0.00308SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr6114178851TC0.00056MARCKS+FALSE(TGCCGC)nSINE,Alu
chr1028971535TA0.00169BAMBI+FALSE
chr310302172GA0.00202TATDN2+FALSE
chr555235866TA0.00073IL6ST-FALSE
chr264119873AT0.00492VPS54-FALSE
chr16282400TC0.00809ICMT-TRUEAluSzSINE,Alu
chr140147817CA0.00982HPCAL4-FALSE
chr1256510698CG0.00944RPL41+FALSE
chr137948912CT0.00084ZC3H12A+FALSE
chr1149581866CG0.00774LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chr721941587GC5.72060E-05CDCA7L-FALSE
chr121545088TC0.00737ECE1-FALSEAluSx1SINE,Alu
chr417488286TG0.00027QDPR-FALSE
chr237429737AG3.16512E-05CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr642854611AG0.00541RPL7L1+TRUEAluScSINE,Alu
chr20309186AG0.00665SOX12+FALSEA-richSINE,Alu
chr10104661031AG0.00265BORCS7-ASMT,AS3MT+TRUEAluYSINE,Alu
chr1168218522AG0.00073.FALSEAluSzSINE,Alu
chr1109181304CA0.00592FAM102B+FALSE
chr439552022TC0.00840UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr3195243007AC3.91570E-06PPP1R2-FALSE
chr116932144AC1.90883E-05NBPF1-FALSE
chr5149823791GT0.00480.FALSE
chr1179326847AG0.00846SOAT1+TRUEAluJoSINE,Alu
chr1049609751AG0.00979MAPK8+FALSE
chr534908535TC0.00054RAD1-FALSEAluSpSINE,Alu
chr3141667460TG0.00193TFDP2-FALSE
chr14103941379CA0.00705MARK3+FALSE
chr116910172GA0.00085NBPF1-FALSE
chr8144684474TC0.00058.FALSE
chr2153506056TC0.00252FMNL2+FALSE
chr132373858AT0.00100PTP4A2-FALSE
chr310290511GT0.00289TATDN2+FALSE
chr1168213597AG0.00481.FALSEAluSx1SINE,Alu
chr191990445AG0.00784CDC7+FALSELFSINE_VertSINE,Alu
chr13416449CA0.00748MEGF6-FALSE
chr744047381GA0.00912POLR2J4,SPDYE1+,-FALSE
chr552388459AT0.00052ITGA2+FALSE
chr121086062GT0.00847RAD52-FALSEL2SINE,Alu
chr626368938CT0.00121BTN3A2+FALSE
chr552393421CT0.00144MOCS2-FALSEL1MA9SINE,Alu
chr1220231263TC0.00300RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr16283264TC0.00284ICMT-TRUEAluSx3SINE,Alu
chr43514695AG1.35580E-12LRPAP1-FALSE
chr74802065CT0.00279FOXK1+FALSE
chr193297609CT8.96972E-06RPL5+FALSE
chr128825418AG0.00525PHACTR4+TRUEAluSgSINE,Alu
chr164935146CT0.00676PPL-FALSE
chr144438961AG0.00013DPH2+FALSEMER3SINE,Alu
chr2202031433AG0.00611CFLAR+FALSESVA_ASINE,Alu
chr825222165AG0.00019DOCK5+FALSE
chr1179843725TC0.00028TOR1AIP2-TRUEAluJbSINE,Alu
chr225962253AT0.00784ASXL2-FALSE
chr1119245854TC0.00078E2F8-FALSE
chr1298943102AG0.00250TMPO+TRUEAluSzSINE,Alu
chr16659505GA0.00405KLHL21-FALSE
chr116893686GC0.00171NBPF1-FALSE
chr110520331CT2.36721E-05.FALSEAluSx1SINE,Alu
chr1767539228GC0.00200.FALSE
chr1100440553AG0.00179SLC35A3+TRUEAluJbSINE,Alu
chr3129033736TC0.00309H1FX-FALSE
chr153291434AG0.00124ZYG11B+TRUEAluJrSINE,Alu
chr129446554CA0.00682EPB41,TMEM200B+,-FALSE
chr237330540TC0.00854.FALSEAluSq2SINE,Alu
chr136032276AT0.00012NCDN+FALSE(CA)nSINE,Alu
chr119595137CT0.00085AKR7L-FALSE
chr2191555980TA0.00913NAB1+FALSE
chr642856917AG0.00148RPL7L1+TRUEAluSpSINE,Alu
chr348787051TC0.00105PRKAR2A-TRUEAluSx3SINE,Alu
chr220818286AC0.00714HS1BP3-FALSE
chr1120163007GA0.00573ZNF697-FALSE
chr1611929653CT0.00333RSL1D1-FALSELTR14BSINE,Alu
chr2191745653TG0.00799GLS+FALSE
chr119543247TC4.83051E-05LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr3156259229TC1.62025E-06SSR3-TRUEAluSq2SINE,Alu
chr618264355GA0.00872DEK-FALSE
chr11595540TC0.00048CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr274645427AG0.00011C2orf81-FALSE
chr2171634349TA0.00104ERICH2+FALSE
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr116944809GC9.47535E-05CROCCP2-FALSE
chr1648387238AG0.00013LONP2,MIR5095+TRUEAluJbSINE,Alu
chr348787633TC0.00287PRKAR2A-TRUEAluSpSINE,Alu
chr315483744AG0.00083EAF1+FALSE
chr147685593AC0.00891TAL1-FALSE(CCACCC)nSINE,Alu
chr1145329095CG0.00261NBPF20,NBPF10+FALSE
chr13545192CG0.00332TPRG1L+FALSE
chr1230416412CG0.00514GALNT2+FALSE
chr1220323448CT0.00223RAB3GAP2-FALSE
chr111347150CA0.00016UBIAD1+FALSE
chr6150045926TC0.00053NUP43-TRUEAluSqSINE,Alu
chr841798912TC0.00892KAT6A-FALSE
chr1179326295AG0.00035SOAT1+TRUE
chr1100150196AG0.00176PALMD+TRUEAluJrSINE,Alu
chr286979093GA0.00591RMND5A+FALSE
chr2174090339AC2.67746E-05ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr168902411AG0.00357PMM2+FALSE
chr1160966301TC7.77749E-07F11R-TRUEAluSgSINE,Alu
chr537288767TC0.00928.FALSEFLAM_CSINE,Alu
chr2203742141TC0.00044.FALSEAluJbSINE,Alu
chr1145323656AT0.00593NBPF20,NBPF10+FALSE
chr1075008841TC0.00088DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr111782935AG0.00067.FALSEAluSxSINE,Alu
chr1240255560GA0.00810FMN2+FALSE(GGC)nSINE,Alu
chr1913884096AG1.54361E-06MRI1+TRUEAluSzSINE,Alu
chr1206566904TC0.00084SRGAP2+FALSE
chr116945027TC2.31134E-07CROCCP2-FALSEL1ME3CzSINE,Alu
chr1118502684GA0.00682WDR3,SPAG17+,-FALSE
chr12133297904AG8.99170E-13PGAM5+TRUEAluJoSINE,Alu
chr220401856TG0.00265SDC1-FALSE
chr2134728144AG2.75061E-05IFNAR1+TRUEAluScSINE,Alu
chr1757279281AG0.00918PRR11+TRUEAluSq2SINE,Alu
chr1225707044CT1.61826E-07ENAH-FALSE
chr116932536CT0.00114NBPF1-FALSEL1MC2SINE,Alu
chr1070502288GA0.00347CCAR1+FALSE
chr934088029CT0.00501DCAF12-FALSE
chr611577085CT1.34362E-05TMEM170B+FALSE
chr344791398TC0.00081KIAA1143-TRUEAluJrSINE,Alu
chr237329261TC0.00123.FALSEAluJr4SINE,Alu
chr1151374016AG0.00822PSMB4+FALSE
chr10114209912AG0.00060VTI1A+TRUEAluSx3SINE,Alu
chr275118856TC1.43220E-05HK2+FALSE(ATTTTA)nSINE,Alu
chr1742876398TC0.00697GJC1-FALSEAluSz6SINE,Alu
chr136186320TC0.00281.FALSEAluSgSINE,Alu
chr717384395AG1.20082E-06AHR+TRUEAluSxSINE,Alu
chr124086807TC0.00352TCEB3+FALSE(T)nSINE,Alu
chr625600772AG0.00269CARMIL1+FALSE
chr2201774775TC0.00872.FALSEAluJr4SINE,Alu
chr144035352CT0.00055PTPRF+FALSE
chr2101622881CA1.48865E-05RPL31+FALSE
chr744918768TC3.66924E-05PURB-TRUEAluSgSINE,Alu
chr1150281011AG0.00016MRPS21+TRUEAluSzSINE,Alu
chr11152310CT0.00133SDF4-FALSE
chr1144868170CT0.00415NBPF20,PDE4DIP+,-FALSE
chr10101992793TC0.00407CWF19L1-TRUEAluJbSINE,Alu
chr72473753CT0.00806CHST12+FALSE(CCGC)nSINE,Alu
chr19163502TC0.00366.FALSEAluSpSINE,Alu
chr1911256697TC0.00039SPC24-TRUEAluJr4SINE,Alu
chr344791536TC4.11776E-05KIAA1143-TRUEAluJrSINE,Alu
chr3191114266TC0.00258CCDC50+FALSE
chr1120163248GA0.00204ZNF697-FALSE
chr1593198678TC0.00064FAM174B-FALSE(GCCGCT)nSINE,Alu
chr2216903621TC0.00611PECR-TRUEAluSx3SINE,Alu
chr111084103TA0.00162TARDBP+FALSE
chr110520819TC0.00034DFFA-TRUEAluSc8SINE,Alu
chr146830257CT0.00208NSUN4+FALSEAluSx1SINE,Alu
chr6153314040GA0.00041MTRF1L-FALSE
chr1144852476TC0.00735NBPF20,PDE4DIP+,-FALSE
chr11654038GA0.00290CDK11B,CDK11A-FALSE
chr111782984AG0.00542.FALSEAluSxSINE,Alu
chr2176791182TC0.00603LNPK-TRUEMSTDSINE,Alu
chr129508350CT0.00859SRSF4-FALSE(GGC)nSINE,Alu
chr19294903CG0.00147H6PD+FALSE
chr18045340CA0.00217PARK7+FALSE
chr743679092GC1.19724E-06COA1-FALSE
chr1949608GA0.00235ISG15+FALSE
chr417803616TC0.00046DCAF16-TRUEAluYSINE,Alu
chr1648387215AG0.00864LONP2,MIR5095+TRUEAluJbSINE,Alu
chr1145369589TC0.00128NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr11417649TG0.00274ATAD3B+FALSE
chr136068184TC0.00177PSMB2-TRUEAluScSINE,Alu
chr116889503TC0.00130NBPF1-FALSEL1MC4SINE,Alu
chr3155660961AG6.62819E-05.FALSEAluSzSINE,Alu
chr179109337GT0.00790IFI44L+FALSELTR26SINE,Alu
chr483812317CA0.00553SEC31A-FALSE
chr1221015760GA0.00758SLCO1B3+FALSE
chr9102744711AT0.00675ERP44-FALSE
chr345721990AG0.00779LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr1272096335AG1.07858E-05TMEM19+FALSEAluSz6SINE,Alu
chr120977856TC0.00232PINK1,PINK1-AS+,-FALSE
chr537291504TC0.00878.FALSEAluSx3SINE,Alu
chr1921474857TC0.00131ZNF708-TRUEAluScSINE,Alu
chr126161108AC7.55238E-06AUNIP-FALSEAluSc8SINE,Alu
chr1158067059AC0.00655KIRREL+FALSE
chr129519665TC0.00680MECR-TRUEAluJbSINE,Alu
chr5135388663AG1.64165E-07TGFBI+FALSE
chr119586501AG0.00055MRTO4+TRUEAluSzSINE,Alu
chr4129796171AG0.00540JADE1+FALSE
chr136067833TC3.75622E-05PSMB2-TRUEAluSzSINE,Alu
chr167874731TC0.00125SERBP1-TRUEAluSx3SINE,Alu
chr1160231910AT0.00051DCAF8-FALSE
chr3101369192CT0.00014ZBTB11-FALSE
chr1109793319CT0.00027CELSR2+FALSE
chr1159887904AT8.82173E-05TAGLN2-FALSE
chr126451672TC0.00912PDIK1L+FALSE
chr133149425AG0.00849SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1591044379TG0.00440IQGAP1+FALSE
chr155207984TA0.00099MROH7-TTC4,TTC4+FALSE
chr1272096318AG0.00547TMEM19+TRUEAluSz6SINE,Alu
chr1144606963GT0.00337NBPF20+FALSE
chr2203742324TC0.00482.FALSEAluJbSINE,Alu
chr118708789AG0.00237RPL27A+TRUEAluSpSINE,Alu
chr5151041873AG0.00136SPARC-FALSE
chr224223353AG0.00083UBXN2A+TRUEAluScSINE,Alu
chr1946053369TC0.00504OPA3-TRUEAluSx1SINE,Alu
chr11309464CT3.88389E-12AURKAIP1-FALSE
chr264119875GA0.00781VPS54-FALSE
chr133409693GA0.00722RNF19B-FALSE
chr1156565049AC0.00169GPATCH4-FALSE
chr1648386425AG0.00152LONP2,MIR5095+TRUEAluSz6SINE,Alu
chr1121134204GT0.00557SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSE(TTTCCT)nSINE,Alu
chr19161550GA0.00196.FALSE
chr1201846630CA7.51318E-05IPO9+FALSE(CA)nSINE,Alu
chr830536544TC5.33169E-07GSR-TRUEAluSpSINE,Alu
chr132508478CT0.00509KHDRBS1+FALSE
chr1631469051TC0.00278.FALSEAluSzSINE,Alu
chr613790848TC0.00344MCUR1-TRUEAluSx1SINE,Alu
chr236776054CT0.00117CRIM1+FALSE
chrX123046741AG0.00169XIAP+TRUEAluSzSINE,Alu
chr126755536AG0.00515LIN28A+TRUEAluScSINE,Alu
chr45830393CT0.00220CRMP1-FALSE
chr110519946TC0.00033.FALSEAluJrSINE,Alu
chr3119212009GA0.00241POGLUT1+FALSE
chr151873951GA1.40484E-05EPS15-FALSE
chr1148556784GA0.00543.FALSE

Differential Expression Gene Analysis