Dataset Overview
RBP
FASTKD1
Knock-Method
shRNA
RBP Family
RAP
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR728BOL
Platform
HiSeq
Pubmed ID
32252787
FASTKD1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of FASTKD1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
AAAS
25.65
20.6
-0.40503
0.00237
0.00782
AADAT
4.81
2.48
-0.85869
5.01573E-06
3.67050E-05
AAED1
6.5
6.58
0.31849
0.03267
0.07035
AAK1
2.42
2.7
0.46547
0.00794
0.02181
AARS
64.38
133.37
1.21681
8.21281E-23
1.17384E-20
AARS2
4.86
2.86
-0.66632
1.69941E-05
0.00011
AASS
8.55
10.52
0.39574
0.00375
0.01151
AATK
1.82
1.24
-1.13542
2.16257E-06
1.74207E-05
ABAT
21.04
9.13
-1.12133
6.68341E-20
6.33782E-18
ABCA1
17.71
20.92
0.38615
0.00169
0.00586
Showing 1 to 10 of 6,576 entries
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Function Analysis of Target Genes of FASTKD1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101556540_101556610_101554169_101554225_101556853_101557853
0.00335
-0.069
DataSet_01_377
View details
AC024560.3
197349057_197349201_197348574_197348739_197350090_197350253
0.00756
0.152
DataSet_01_377
View details
AC093838.4
132277386_132277515_132277107_132277239_132277669_132277994
0.00227
0.326
DataSet_01_377
View details
ACAA1
38167652_38167832_38167316_38167372_38168000_38168191
0.00444
0.04
DataSet_01_377
View details
ACAA1
38167652_38167843_38167316_38167372_38168000_38168191
0.00503
0.058
DataSet_01_377
View details
ACADM
76199212_76199313_76198522_76198607_76200475_76200556
0.00485
-0.052
DataSet_01_377
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ACOT9
23754035_23754133_23751288_23751334_23761241_23761390
0.00215
-0.2
DataSet_01_377
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ACSL3
223765391_223765498_223752547_223752606_223773450_223773754
0.00052
-0.093
DataSet_01_377
View details
ACSS2
33509765_33509795_33509450_33509669_33511125_33511234
0.00076
0.087
DataSet_01_377
View details
ACSS2
33509765_33509906_33509450_33509669_33511125_33511234
0.00237
0.073
DataSet_01_377
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Showing 1 to 10 of 453 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9264754_9264807_9264904_9265132_9262909_9262930
0.00000
-0.267
DataSet_01_377
View details
ACSL3
223752547_223752606_223765391_223765498_223725651_223725976
0.00179
0.073
DataSet_01_377
View details
ACSL4
108926364_108926601_108939372_108939425_108925947_108926125
0.00003
-0.074
DataSet_01_377
View details
ACTN4
39218585_39218666_39218955_39219021_39217596_39217743
0.00037
-0.145
DataSet_01_377
View details
ACTR3
114670748_114670804_114684921_114685032_114647536_114647900
0.00089
-0.2
DataSet_01_377
View details
ADAM9
38940486_38940592_38948777_38948865_38940159_38940240
0.00000
0.216
DataSet_01_377
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ADH6
100131571_100131659_100134762_100134904_100129824_100130085
0.00296
-0.147
DataSet_01_377
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AFP
74306318_74306530_74309067_74309161_74303890_74304023
0.00000
-0.01
DataSet_01_377
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AHSG
186334975_186335164_186337645_186337729_186334231_186334316
0.00000
-0.108
DataSet_01_377
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AHSG
186334975_186335139_186336079_186336280_186334231_186334316
0.00001
-0.013
DataSet_01_377
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Showing 1 to 10 of 126 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38167652_38168191_38168000_38168191_38167316_38167372
0.00520
0.059
DataSet_01_377
View details
ACSS2
33509588_33509795_33509588_33509669_33511125_33511234
0.00005
0.066
DataSet_01_377
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AP3M1
75885883_75886113_75885905_75886113_75884137_75884282
0.00687
0.076
DataSet_01_377
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ASPSCR1
79974816_79974989_79974816_79974964_79975184_79975279
0.00083
-0.249
DataSet_01_377
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ATP5J2-PTCD1
99063733_99063787_99063751_99063787_99057708_99057816
0.00740
-0.068
DataSet_01_377
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BPTF
65941524_65942441_65941524_65942012_65943841_65943924
0.00100
-0.154
DataSet_01_377
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BTF3
72794232_72794411_72794232_72794383_72794958_72795009
0.00949
0.007
DataSet_01_377
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00573
0.054
DataSet_01_377
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C20orf27
3735035_3735166_3735043_3735166_3734154_3734805
0.00382
0.136
DataSet_01_377
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CNBP
128890476_128890614_128890497_128890614_128890288_128890381
0.00086
0.136
DataSet_01_377
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Showing 1 to 10 of 59 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTG1
79478213_79478829_79478213_79478652_79478928_79479168
0.00568
0.008
DataSet_01_377
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AGFG1
228418419_228418511_228418425_228418511_228416674_228416833
0.00980
-0.13
DataSet_01_377
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ALAD
116154398_116154615_116154398_116154449_116155726_116155914
0.00401
0.167
DataSet_01_377
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ANKHD1
139818045_139818202_139818087_139818202_139815688_139815842
0.00389
0.25
DataSet_01_377
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APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00597
-0.011
DataSet_01_377
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AQP7
33384947_33385288_33384947_33385229_33385646_33385864
0.00620
-0.457
DataSet_01_377
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ASGR2
7017492_7017717_7017492_7017706_7017933_7018130
0.00111
0.018
DataSet_01_377
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ASPSCR1
79970031_79970159_79970106_79970159_79969418_79969481
0.00736
-0.029
DataSet_01_377
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AUP1
74754067_74754279_74754067_74754248_74754374_74754490
0.00255
-0.151
DataSet_01_377
View details
BIRC5
76212046_76212862_76212744_76212862_76210760_76210870
0.00032
-0.052
DataSet_01_377
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Showing 1 to 10 of 88 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38167316_38168191_38167316_38167372_38168000_38168191
0.00300
0.255
DataSet_01_377
View details
ACAD11
132297639_132298402_132297639_132297900_132298335_132298402
0.00028
-0.275
DataSet_01_377
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ACADVL
7127639_7127871_7127639_7127712_7127798_7127871
0.00697
0.208
DataSet_01_377
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00003
0.014
DataSet_01_377
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ACTB
5567634_5568350_5567634_5567816_5567911_5568350
0.00007
0.011
DataSet_01_377
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ACTB
5568791_5569294_5568791_5569031_5569165_5569294
0.00640
0.012
DataSet_01_377
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ACTG1
79477952_79478652_79477952_79478134_79478213_79478652
0.00455
0.009
DataSet_01_377
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AKR1B1
134132049_134132813_134132049_134132133_134132731_134132813
0.00234
0.08
DataSet_01_377
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ANKRD13D
67066528_67067082_67066528_67066595_67067000_67067082
0.00846
-0.166
DataSet_01_377
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AP1G2
24031170_24031624_24031170_24031394_24031496_24031624
0.00639
-0.106
DataSet_01_377
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
11783106
A
G
0.00022
.
FALSE
AluSx
SINE,Alu
chr1
26608012
C
A
0.00564
SH3BGRL3
+
FALSE
chr1
144595935
G
A
0.00359
NBPF20
+
FALSE
AluJb
SINE,Alu
chr1
6283306
T
C
0.00275
ICMT
-
TRUE
AluSx3
SINE,Alu
chr1
33148635
A
G
5.38540E-05
SYNC,RBBP4
+,-
FALSE
AluSc
SINE,Alu
chr1
1647871
T
C
0.00906
CDK11B,CDK11A
-
FALSE
chr1
100388748
T
C
0.00445
AGL
+
FALSE
chr1
144881463
C
T
0.00147
NBPF20,PDE4DIP
+,-
FALSE
chr1
209605640
A
C
0.00581
MIR205HG
+
FALSE
(AGC)n
SINE,Alu
chr1
23408939
T
A
1.04314E-06
KDM1A
+
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression