Dataset Overview
RBPDDX28
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR205VSQ
PlatformHiSeq
Pubmed ID32252787

DDX28 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX28
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX28


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr5176728458GT0.00901RAB24-FALSE
chr9138798859CA0.00291CAMSAP1-FALSE
chr2224621887TC0.00373AP1S3-FALSEAluScSINE,Alu
chr1175116734CA0.00453RPS3+FALSE
chr5140594467GA0.00045PCDHB13+FALSE
chr12133298069AG6.69127E-09PGAM5+TRUEAluJoSINE,Alu
chr690344222TC0.00451LYRM2-TRUEAluJoSINE,Alu
chr1204374665GA0.00717PPP1R15B-FALSE
chr77283569GA0.00032C1GALT1+FALSE(AT)nSINE,Alu
chr510655842CT0.00024ANKRD33B+FALSE
chr285776644TC0.00127GGCX-TRUEAluSz6SINE,Alu
chr5175816760TA0.00016.FALSE
chr1114306374GA0.00017RSBN1-FALSE
chr1115275398TG0.00474CSDE1-FALSE
chr185278665AG0.00242.FALSE
chr644222157GA0.00856SLC35B2-FALSE
chr19161366TC0.00189.FALSEAluSxSINE,Alu
chr1160966299TC0.00033F11R-TRUEAluSgSINE,Alu
chr347628810TA0.00934SMARCC1-FALSE
chr268402797TA0.00656PNO1+FALSE
chr2143638992TA0.00089KYNU+FALSE
chr12133298417AG0.00084PGAM5+TRUEAluSpSINE,Alu
chr1811852628CT0.00048GNAL,CHMP1B+FALSE
chr483406545AG0.00156TMEM150C-FALSE
chr5176887511AC0.00662DBN1-FALSE
chr2025428587AG0.00137GINS1+TRUEAluJbSINE,Alu
chr1930192475GA0.00575C19orf12-FALSEMER2SINE,Alu
chr122854931CA0.00238ZBTB40+FALSEA-richSINE,Alu
chr11594315CT0.00347CDK11B,SLC35E2B-FALSE
chr220818286AC0.00714HS1BP3-FALSE
chr41228741GA0.00095CTBP1-FALSE
chr110519936TC0.00354.FALSEAluJrSINE,Alu
chr1173793106CT0.00772CENPL-FALSE
chr6107113955AG0.00265QRSL1+TRUEAluSgSINE,Alu
chr128835937AG2.00244E-07SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr116889413TC0.00016NBPF1-TRUEL1MC4SINE,Alu
chr1153599390TC0.00135S100A13-FALSE
chr310005650CT0.00698EMC3-FALSE
chr236776054CT0.00117CRIM1+FALSE
chr269685864AC0.00610AAK1-FALSE(CA)nSINE,Alu
chr119542415TC0.00204LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr140229368AG0.00209BMP8B,PPIE+,-FALSE
chr399517479TC8.06312E-05MIR548G-FALSE(TG)nSINE,Alu
chr3196079389TC0.00509.FALSEAluSxSINE,Alu
chr146032974TC0.00196AKR1A1+FALSE
chr273480136TA0.00281CCT7+FALSE
chr517276055TC0.00784BASP1+FALSE(TC)nSINE,Alu
chr310192709CT0.00082VHL+FALSEAluSx1SINE,Alu
chr1184661932AG0.00063EDEM3-FALSE
chr1936575645GA0.00590WDR62+FALSE
chr352567617AG0.00025NT5DC2-FALSEG-richSINE,Alu
chr3196466874GT0.00226PAK2+FALSE
chr146076543AG0.00989NASP+TRUEAluSxSINE,Alu
chr1101541172AG6.48917E-05LOC102606465+TRUEMLT1KSINE,Alu
chr111979809AC0.00836KIAA2013-FALSE
chr1533064461CT0.00653FMN1-FALSE
chr9130268408TC6.51633E-05FAM129B-FALSE(CTCA)nSINE,Alu
chr299812289AG0.00282MRPL30+TRUEAluSxSINE,Alu
chr1144874815TC0.00701NBPF20,PDE4DIP+,-FALSE
chr349395695AC0.00159GPX1-FALSE
chr116933583TC0.00050NBPF1-FALSEGA-richSINE,Alu
chr594050487TA0.00380MCTP1-FALSE
chr136068369TC0.00252PSMB2-TRUEAluScSINE,Alu
chr1533063527CT0.00183FMN1-FALSEAluYk3SINE,Alu
chr1144932197TA0.00430NBPF20,PDE4DIP+,-FALSE
chr5179720333AG0.00308.FALSE
chr140537942AC0.00955CAP1+FALSE(A)nSINE,Alu
chr439551975TC5.31269E-07UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr110521238TC0.00096DFFA-TRUEAluYSINE,Alu
chr2240954110AG0.00605NDUFA10-FALSE
chr119543356TC0.00256LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1590819418AG0.00516.FALSEAluSxSINE,Alu
chr4154257510AC0.00121TRIM2+FALSE(A)nSINE,Alu
chr110520331CT0.00816.FALSEAluSx1SINE,Alu
chr2217366919AG0.00709.FALSEAluSz6SINE,Alu
chr2191065246TA0.00594C2orf88+FALSE
chr178142911TC0.00925ZZZ3-TRUEAluSxSINE,Alu
chr1450361171CT0.00017ARF6+FALSE(T)nSINE,Alu
chr310193511AG0.00116VHL+TRUEAluJrSINE,Alu
chr1916661431TC0.00017SLC35E1-TRUEAluSzSINE,Alu
chr3129033736TC0.00309H1FX-FALSE
chr138174665GA0.00339CDCA8+FALSE
chr674493432AC0.00611CD109+FALSE
chr153289547AG0.00646ZYG11B+TRUEAluSzSINE,Alu
chr375779619TA0.00061ZNF717-FALSE
chr2132278713TC0.00317LOC150776+FALSE
chr1148251083TC0.00041NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr373116347TA0.00109PPP4R2+FALSE
chr642857028AG0.00064RPL7L1+TRUEAluSpSINE,Alu
chr16683581AC0.00504PHF13+FALSE
chr3195963400TG0.00155.FALSE
chr1120166681GA0.00879ZNF697-FALSE
chr125655853AG0.00147RSRP1,RHD+,-FALSEAluSzSINE,Alu
chr2128620437TA0.00388AMMECR1L-FALSE
chr248605828TA0.00650FOXN2+FALSE(T)nSINE,Alu
chr1100549600GT0.00181SASS6-FALSE
chr348894565TA0.00142SLC25A20-FALSE
chr1207247477TC0.00078PFKFB2+FALSEMER5BSINE,Alu
chr1539879717GA0.00162THBS1+FALSE
chr164125439AC3.63698E-07PGM1+FALSE
chr2233257176AG0.00930SYN3,TIMP3+,-FALSE
chr116952481AG5.15865E-05CROCCP2-FALSE
chr1990773CT0.00705AGRN+FALSE
chr145975673AG0.00410MMACHC+TRUEAluSx4SINE,Alu
chr1591044382AG0.00453IQGAP1+FALSE
chr2151326173AC0.00143RND3-FALSE
chr1160967856TC0.00100F11R-TRUEAluSpSINE,Alu
chr2171849612TC0.00364TLK1-FALSE
chr7117832138GA0.00885LSM8+FALSE
chr1396506664AG5.36176E-05UGGT2-FALSE
chr118709240AG0.00431RPL27A+TRUEAluYk2SINE,Alu
chr1168218504TC0.00748.FALSEAluSzSINE,Alu
chr1108113839TC0.00027VAV3-FALSE
chr2232319524TA0.00040NCL-FALSE
chr139990456GA0.00749BMP8A,PPIEL+,-FALSEL2bSINE,Alu
chr1746803538CT0.00492HOXB13-FALSE
chr1200375418CT0.00425ZNF281-FALSE
chr224225554AG0.00419.FALSEAluSq2SINE,Alu
chr9130268408TC0.00416FAM129B-FALSE(CTCA)nSINE,Alu
chr35257975AT9.78592E-05EDEM1+FALSE
chr1347345467GT0.00495ESD-FALSE
chr717384437AG0.00192AHR+TRUEAluSxSINE,Alu
chr345636335AG0.00262LIMD1+FALSE(AC)nSINE,Alu
chr122400707CG0.00158CDC42+FALSEAluSc8SINE,Alu
chr128836975AG0.00023SNHG3,RCC1+TRUEAluScSINE,Alu
chr3120128940AG0.00434FSTL1-FALSE
chr136392543GT0.00971.FALSE(T)nSINE,Alu
chr193803522TC0.00163CCDC18-AS1-TRUEAluJrSINE,Alu
chr315115284GA0.00305RBSN-FALSE
chr116889414TC0.00858NBPF1-TRUEL1MC4SINE,Alu
chr1256510704GA0.00042RPL41+FALSE
chr3195962244GT0.00083.FALSE
chr258316814AG0.00257VRK2+FALSE
chr127992799TA0.00017IFI6-FALSEFAMSINE,Alu
chr1165877666TC0.00327UCK2+FALSE(T)nSINE,Alu
chr2189459785CT0.00262GULP1+FALSE
chr2202038657AG0.00354.FALSEAluSx1SINE,Alu
chr144447004GA0.00768B4GALT2+FALSE(CAG)nSINE,Alu
chr126774225AG0.00614DHDDS+TRUEAluSz6SINE,Alu
chr2206986233TC0.00491.FALSEAluSzSINE,Alu
chr1245017464TA0.00624HNRNPU,SNORA100-FALSE
chr2236677551TC7.06365E-05MYH9-FALSE
chr178483452CT0.00094DNAJB4+FALSEL1MB7SINE,Alu
chr1670284570AC0.00028EXOSC6-FALSEAluSxSINE,Alu
chr16694574GA0.00983THAP3,DNAJC11+,-FALSE
chr5122165501AT0.00051SNX2+FALSE(AC)nSINE,Alu
chr110093371CT0.00264UBE4B+FALSE
chr12133635613TC0.00024.FALSE
chr136770605CT0.00041THRAP3+FALSE(T)nSINE,Alu
chr116717888GA0.00118SZRD1+FALSE
chr312624070CT2.78764E-07MKRN2+FALSE
chr110519973TC0.00586.FALSEAluJrSINE,Alu
chr1100654813TC0.00352DBT-TRUEAluSzSINE,Alu
chr128661657AG0.00910MED18+TRUEAluSgSINE,Alu
chr6160113872AG0.00863SOD2-FALSE
chr110041432AG0.00132NMNAT1+TRUEAluYj4SINE,Alu
chr1071993094TG0.00078PPA1-FALSE
chr124022912GA4.29449E-05RPL11+FALSE
chr114150032CT0.00163PRDM2+FALSE
chr315114486TC3.99101E-05RBSN-TRUEAluYSINE,Alu
chr116909129TC0.00131NBPF1-FALSE
chr119542250TC0.00780LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr5159492103TG0.00332TTC1+FALSE
chr3195393406CT0.00690SDHAP2+FALSE
chr439551167TC0.00361UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr119542310TC0.00582LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1205687354TC0.00012NUCKS1-FALSE(T)nSINE,Alu
chr136522460AG0.00407.FALSEAluScSINE,Alu
chr166099013CA7.87351E-06LEPR+FALSE
chr1956090351CT1.52943E-09ZNF579-FALSE
chr211053740CT0.00402KCNF1+FALSE
chr237429737AG3.16512E-05CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr1160967833TC6.62581E-12F11R-TRUEAluSpSINE,Alu
chr101086801GC0.00421IDI2-AS1,IDI1+,-FALSE
chr116933749AG0.00764NBPF1-FALSEGA-richSINE,Alu
chr127182750GC0.00141.FALSE
chr1916663345TC0.00304SLC35E1-TRUEAluSgSINE,Alu
chr153712215GT0.00458LRP8-FALSE
chr1117530213GT0.00256PTGFRN+FALSE
chr1120162635AT0.00203ZNF697-FALSE
chr1201350983CT0.00768LAD1-FALSE
chr1165404870CT0.00160PCNX3+FALSE
chr1227574427AG7.32829E-06ARNTL2,ARNTL2-AS1+,-FALSEAluSzSINE,Alu
chr3195694448CT0.00289SDHAP1-FALSE
chr6158613390TC0.00416GTF2H5+FALSE
chr1916661541TC0.00120SLC35E1-TRUEAluSzSINE,Alu
chr2242122440CA0.00354PPP1R7+FALSE
chr1143399383TA0.00053.FALSEL1MC4SINE,Alu
chr11650787TC0.00071CDK11B,CDK11A-FALSE
chr1326539AG0.00719.FALSE
chr1145511998AG0.00715NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2128602500TC4.07621E-06.FALSEAluSq2SINE,Alu
chr255516908AG0.00016CCDC88A-FALSE(GA)nSINE,Alu
chr1157963370CG0.00445KIRREL+FALSE
chr132385071TA0.00436PTP4A2-FALSE
chr1260173406CT0.00708SLC16A7+FALSE
chr1150446056GA0.00945RPRD2+FALSE(A)nSINE,Alu
chr210923581CT0.00593ATP6V1C2,PDIA6+,-FALSE
chr286251114TC0.00150.FALSEAluSxSINE,Alu
chr133086905TC0.00598ZBTB8OS-FALSEAluYSINE,Alu
chr116203171CT3.13656E-06SPEN+FALSE
chr186852621AG0.00930ODF2L-FALSE
chr126450101AG0.00764PDIK1L+FALSE
chr917829GA0.00142WASH1-FALSE
chr1765335394TC5.10125E-06PSMD12-TRUEAluSxSINE,Alu
chr1675479331TC0.00725TMEM170A-TRUEAluJbSINE,Alu
chr1156107534CT0.00168LMNA+FALSE
chr147142538GA7.23026E-06EFCAB14-AS1,EFCAB14+,-FALSE
chr1911560483AG0.00775PRKCSH+TRUEAluSxSINE,Alu
chr1900720AT0.00065KLHL17+FALSE(TTTA)nSINE,Alu
chr136770045TC0.00488THRAP3+FALSE
chr116913677TC0.00638NBPF1-FALSE
chr116703162AT0.00726MRPL17-FALSE
chr1179326882AG0.00020SOAT1+TRUEAluJoSINE,Alu
chr1160967899TC0.00011F11R-TRUEAluSpSINE,Alu
chr1145688664AT0.00298NBPF20,NBPF10,RNF115+FALSE
chr5130540368AC0.00420LYRM7+FALSETigger4aSINE,Alu
chr2128063526CA0.00759MAP3K2-FALSE
chr1180082703CA2.04280E-05CEP350+FALSE
chr119586437AG0.00056MRTO4+TRUEAluSzSINE,Alu
chr261277775AG0.00113PEX13+TRUEAluYSINE,Alu
chr233007710CT0.00743TTC27+FALSE
chr19162362TC0.00526.FALSEAluSxSINE,Alu
chr310192744AG3.36147E-05VHL+TRUEAluSx1SINE,Alu
chr2101623533CT0.00784RPL31+FALSE
chr112024235CT0.00395PLOD1+FALSE
chr1184761365AG0.00758FAM129A-FALSEAluJoSINE,Alu
chr145244414TA0.00750.FALSE
chr9124094998TG0.00299GSN+FALSE(TG)nSINE,Alu
chr5134061340TA0.00493SEC24A+FALSE
chr1153917621GC0.00020DENND4B-FALSE
chr4123859284CT0.00034SPATA5+FALSE
chr12120899168AG6.24570E-05GATC+TRUEAluJrSINE,Alu
chr192976590GA0.00629EVI5-FALSE
chr1179042692AG0.00707FAM20B+TRUEAluSx1SINE,Alu
chr145226084GA0.00970KIF2C+FALSE
chr19163334TC0.00074.FALSEAluSpSINE,Alu
chr1179326847AG0.00846SOAT1+TRUEAluJoSINE,Alu
chr167874697TC4.44446E-05SERBP1-TRUEAluSx3SINE,Alu
chr479447807GC0.00339FRAS1+FALSE
chr919376252AT0.00367.FALSE
chr116933629AG0.00299NBPF1-FALSEGA-richSINE,Alu
chr110517512TC0.00498.FALSEAluSx1SINE,Alu
chr1120572572CT0.00084NOTCH2-FALSE
chr1570178GA0.00787.FALSE
chr634213986TA0.00262HMGA1+FALSE
chr11126147713CG0.00384FOXRED1+FALSE
chr146075604AG0.00155NASP+TRUEAluSx4SINE,Alu
chr193617406AT0.00275TMED5-FALSE
chr1929703961AC0.00226UQCRFS1-FALSE
chr1565442506TC0.00088CLPX-TRUEAluSg4SINE,Alu
chr1220231455TC0.00274RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr133148706AG0.00087SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr3179117266TC0.00111GNB4-TRUEAluSzSINE,Alu
chr111783902AG0.00336.FALSEAluSqSINE,Alu
chr136534736AG0.00016.FALSEAluJoSINE,Alu
chr1144828765AT0.00976NBPF20,NBPF9+FALSE
chr110517352TC0.00064.FALSEAluJrSINE,Alu
chr121793735CG0.00099NBPF3+FALSE
chr185785549TC0.00621DDAH1-FALSE
chr553842079CT0.00067SNX18+FALSE
chr1168215575GA0.00688ANKRD36BP1-FALSE
chr2112252628GT7.26456E-05MIR4435-2HG-FALSE
chrX3523050CA0.00043PRKX-FALSE
chr5121362874AG0.00022SRFBP1+TRUEFRAMSINE,Alu
chr189447854GT0.00310KYAT3,RBMXL1-FALSE
chr237328013TC0.00010.FALSE
chr112677549TA1.84464E-05DHRS3-FALSE(A)nSINE,Alu
chr127202812TC0.00356.FALSEAluSq2SINE,Alu
chr1145688973AG0.00283NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr2174090630CA0.00025ZAK,MLK7-AS1+,-FALSE
chr178187733GA0.00388USP33-FALSE
chr1186946912GA0.00414PLA2G4A+FALSE
chr153680205CT9.80404E-07C1orf123-FALSE
chr146075791AG0.00120NASP+TRUEAluSx4SINE,Alu
chr147905554CG0.00297FOXD2+FALSE
chr5125961623AG6.78430E-09PHAX+TRUEAluSz6SINE,Alu
chr133148210AG0.00114SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1145586403GT0.00075NBPF20,NBPF10,PIAS3+FALSE
chr425236017TC0.00291PI4K2B+FALSE
chr237327670TC0.00021.FALSE
chr362189314CT0.00018PTPRG+FALSE
chr570503889CA0.00131.FALSE
chr274686329CT0.00640INO80B-WBP1,WBP1+FALSE
chr1075009591TC8.39163E-08DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr287777087TC0.00737LINC00152+FALSE
chr3183889337AT3.46641E-05DVL3+FALSE
chr344790759TC1.45198E-07KIAA1143-TRUEAluYSINE,Alu
chr128835847AG5.60567E-05SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1243289448GA0.00036CEP170-FALSE
chr2239973454TC0.00091HDAC4-FALSE
chr237333930TC0.00073EIF2AK2-FALSEAluSzSINE,Alu
chr5149763305AG0.00640TCOF1+FALSE
chr1180854783TC0.00292XPR1+FALSE
chr9125887703AC0.00067STRBP-FALSE
chr555235967AG0.00639IL6ST-FALSE(AT)nSINE,Alu
chr1146250905GC0.00444NBPF20,NBPF10,NBPF25P+FALSE
chr1681745173CA0.00179CMIP+FALSE
chr2133032035TA1.90109E-05SOD1+FALSE
chr297020049TC0.00070NCAPH+FALSE
chr1214557685CA0.00205PTPN14-FALSE
chr237327670TC0.00297.FALSE
chr122854931CA7.08508E-09ZBTB40+FALSEA-richSINE,Alu
chr1204526713AG0.00078MDM4+TRUEAluSxSINE,Alu
chr136388197CT0.00315AGO1+FALSE
chr285546320GT0.00749TGOLN2-FALSEAluScSINE,Alu
chr5135382989GC7.70449E-09TGFBI+FALSE
chr146075720AG0.00105NASP+TRUEAluSx4SINE,Alu
chr11594977TC0.00487CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr2206982255TC0.00431.FALSEAluSg7SINE,Alu

Differential Expression Gene Analysis