Dataset Overview
RBPEIF4G2
Knock-MethodshRNA
RBP FamilyMIF4G
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR040FSN
PlatformHiSeq
Pubmed ID32252787

EIF4G2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EIF4G2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EIF4G2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2128620438CA0.00230AMMECR1L-FALSE
chr122419433TG0.00156CDC42+FALSE
chr1741144251TG0.00014RUNDC1+FALSE
chr19643873AG0.00064.FALSEAluYSINE,Alu
chr140537947AC0.00295CAP1+FALSE
chr3196079305TC0.00161.FALSEAluSxSINE,Alu
chr5174956218AG0.00953SFXN1+TRUEAluSpSINE,Alu
chrX77083617TC3.46806E-05MAGT1-TRUEAluSz6SINE,Alu
chr116933135GT0.00937NBPF1-FALSEL1MC2SINE,Alu
chr19163393TC0.00327.FALSEAluSpSINE,Alu
chr179115905TC0.00113IFI44+FALSE
chr7116437206AG0.00118MET+FALSE
chr1145281543CT0.00031NBPF20,NOTCH2NL+FALSE
chr2233446266CT0.00177EIF4E2+FALSE
chr141236854TA0.00075NFYC+FALSE(T)nSINE,Alu
chr1145500925TA0.00997NBPF20,NBPF10,LIX1L+FALSE
chr261764920CA0.00363XPO1-FALSE
chr744841799AG0.00693PPIA+TRUEAluSxSINE,Alu
chr1154554965GA0.00019ADAR-FALSE
chr11419823AG0.00816ATAD3B+TRUEAluYk2SINE,Alu
chr255452458GT0.00113CLHC1-FALSE
chr133148287AG0.00052SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr116889624TC0.00794NBPF1-TRUE
chr399463810GT0.00496MIR548G,COL8A1+,-FALSE
chr285776832CT0.00514GGCX-FALSE
chr128836975AG0.00202SNHG3,RCC1+TRUEAluScSINE,Alu
chr76501819AT0.00037KDELR2-FALSE
chr133071096AG0.00139ZBTB8A+TRUEAluSx1SINE,Alu
chr136534934AG0.00464.FALSEAluJoSINE,Alu
chr110517314TC0.00288.FALSEAluJrSINE,Alu
chr11650801TC0.00761CDK11B,CDK11A-FALSE
chr11337737GC2.51903E-05MRPL20-FALSE
chr1180013235TG0.00319CEP350+FALSE
chr110521238TC0.00096DFFA-TRUEAluYSINE,Alu
chr299813003AG0.00046MRPL30+TRUEAluJbSINE,Alu
chr128785597GC0.00595PHACTR4+FALSE
chr1256736075CT0.00262STAT2-FALSEAluSpSINE,Alu
chr315296357AT3.39714E-05SH3BP5,SH3BP5-AS1+,-FALSE
chr13395039GA0.00027ARHGEF16+FALSE
chr6159396143TC0.00185.FALSEAluScSINE,Alu
chr194660609CT0.00383ARHGAP29-FALSE
chr1156044222GT0.00758MEX3A-FALSE(T)nSINE,Alu
chr19160963TC0.00130.FALSEAluJbSINE,Alu
chr163881552CT0.00021ALG6+FALSE
chr310192596AG7.92003E-05VHL+TRUEAluSx1SINE,Alu
chr119586532AG0.00188MRTO4+TRUEAluSzSINE,Alu
chr1110023610GA0.00636SYPL2+FALSE
chr1182569318GT0.00101RGS16-FALSE
chr144035352CT0.00055PTPRF+FALSE
chr613790888TC0.00442MCUR1-TRUEAluSx1SINE,Alu
chr16713251AG0.00628WDR90+TRUEAluSxSINE,Alu
chr1919792288AG0.00379ZNF101+TRUEAluJbSINE,Alu
chr1148556726GT0.00758.FALSE
chr2242447628TG0.00674STK25-FALSE
chr1475202402AG0.00141FCF1+TRUEAluScSINE,Alu
chr16583538TC0.00455NOL9-TRUEAluSqSINE,Alu
chr123835794AG0.00132E2F2-FALSE
chr532124827GT0.00047GOLPH3-FALSE
chr1156163906CT0.00130SLC25A44+FALSE
chr1475202698AG6.15110E-05FCF1+TRUEAluScSINE,Alu
chr579923292CG0.00305DHFR-FALSEAluJrSINE,Alu
chr1234740975GA0.00106IRF2BP2-FALSE
chr167451521AT0.00049MIER1+FALSE
chr286947783CT0.00515RNF103-CHMP3,RMND5A+,-FALSE
chr356655865AG0.00970FAM208A-FALSE(A)nSINE,Alu
chr136602178AT0.00764TRAPPC3-FALSE
chr2102508658TA0.00275MAP4K4+FALSE
chr5151041874AC0.00060SPARC-FALSE
chr16583066TC0.00180NOL9-TRUEAluSx4SINE,Alu
chr1183094547TC0.00277LAMC1+FALSE
chr110519982TC0.00417.FALSEAluJrSINE,Alu
chr128825805GA0.00115PHACTR4+FALSEAluSpSINE,Alu
chr344791398TC0.00204KIAA1143-TRUEAluJrSINE,Alu
chr35260057AT0.00117EDEM1+FALSE
chr47761114GA8.00249E-13AFAP1,AFAP1-AS1+,-FALSE
chr128825418AG0.00046PHACTR4+TRUEAluSgSINE,Alu
chr11534205GA1.69659E-11FNDC10-FALSE
chr856985611AT0.00028RPS20-FALSE
chrX54587290AG0.00504GNL3L+TRUEAluSq2SINE,Alu
chr1145513017AG0.00037NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1205687358TC0.00432NUCKS1-FALSE(T)nSINE,Alu
chr937503313AG0.00584POLR1E+TRUEAluJbSINE,Alu
chr9136209396CT0.00126MED22-FALSE
chr132385070TA0.00593PTP4A2-FALSE
chr224227417AG0.00831.FALSEAluScSINE,Alu
chr1156564726TC0.00995GPATCH4-FALSE
chr5149363214AG0.00040SLC26A2+TRUEAluJrSINE,Alu
chr1828571649AT0.00301DSC3-FALSEMER65CSINE,Alu
chr128836900AG0.00311SNHG3,RCC1+TRUEAluScSINE,Alu
chr11718810GA5.85228E-05GNB1-FALSE
chr128825418AG0.00961PHACTR4+TRUEAluSgSINE,Alu
chr8104343686GA0.00031FZD6+FALSE
chr1110913120CT0.00627SLC16A4-FALSE
chr5109204057TA0.00614MAN2A1+FALSE
chr12125512540AG7.43833E-09.FALSE
chr110519048TC0.00637.FALSEAluSx3SINE,Alu
chr2204055454TC0.00293NBEAL1+FALSE
chr1145512073AG0.00066NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr7135291501TC0.00627NUP205+FALSE
chr1244572645TG0.00103ADSS-FALSE
chr152375677TC0.00542RAB3B-FALSEMIRbSINE,Alu
chr111347150CA0.00016UBIAD1+FALSE
chr269548320CT7.68354E-05GFPT1-FALSE
chr110518756TC0.00600.FALSEAluSx1SINE,Alu
chr140974799TC0.00038EXO5+FALSE
chr1144932151GT0.00294NBPF20,PDE4DIP+,-FALSE
chr127861184GT0.00425AHDC1-FALSE(TCTTTT)nSINE,Alu
chr341281407GT0.00011CTNNB1+FALSE
chr1939433138GA0.00276FBXO17-FALSEAluJbSINE,Alu
chr1757279234AG0.00293PRR11+TRUEAluSq2SINE,Alu
chr1463841402AC0.00692PPP2R5E-FALSE
chr136068369TC0.00207PSMB2-TRUEAluScSINE,Alu
chr1185069687CT0.00072RNF2+FALSE
chr1610623566TC0.00019EMP2-TRUEAluSpSINE,Alu
chr1540955103AG0.00372.FALSEAluJbSINE,Alu
chr1224575827TC0.00214WDR26-FALSE
chr582877162GA0.00296VCAN+FALSE(A)nSINE,Alu
chr146032974TC0.00196AKR1A1+FALSE
chr5150647719TC0.00112GM2A+FALSEAluScSINE,Alu
chr136770073AT4.33965E-05THRAP3+FALSE
chr1145512166TA0.00823NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr110521103TC0.00788DFFA-TRUEAluYSINE,Alu
chr456295160TA0.00187CLOCK-FALSE(T)nSINE,Alu
chr1958356376AG0.00061ZNF587B+TRUEAluSxSINE,Alu
chr556177848TA0.00986MAP3K1+FALSE
chr286249906TC0.00352LOC90784-TRUEAluJrSINE,Alu
chr269688917TC0.00254AAK1-TRUEAluSq2SINE,Alu
chr2216903620TC0.00623PECR-TRUEAluSx3SINE,Alu
chr3195415493CT0.00126LINC00969,SDHAP2+FALSEL1ME2SINE,Alu
chr116893691CA0.00170NBPF1-FALSE
chr1207942432AG0.00029CD46+TRUEAluSg4SINE,Alu
chr256150885GA0.00624EFEMP1-FALSE
chr145975358AG0.00089MMACHC+TRUEAluSg7SINE,Alu
chr1464951277TC0.00077ZBTB25-TRUEAluSpSINE,Alu
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr11252513TC0.00670CPSF3L-TRUEAluSpSINE,Alu
chr5148382005CA8.42472E-06SH3TC2-FALSE
chr190401562CA0.00057LRRC8D+FALSE
chr1150337289GT0.00020RPRD2+FALSE
chr28996878AT9.26766E-05MBOAT2-FALSEAluSzSINE,Alu
chr12520435GC0.00041FAM213B+FALSE
chr128661576AG0.00625MED18+TRUEAluSgSINE,Alu
chr128835934AG0.00069SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1100489452AG0.00741SLC35A3+TRUEAluScSINE,Alu
chr126608009TA0.00496SH3BGRL3+FALSE
chr642856156AG0.00105RPL7L1+TRUEAluSzSINE,Alu
chr495586224AG0.00053PDLIM5+FALSE
chr1180247476TC0.00890.FALSE
chr124999468GT0.00075SRRM1+FALSE(T)nSINE,Alu
chr811666384CT0.00029FDFT1+FALSE
chr1173457017CT0.00036PRDX6+FALSE
chr1226923264GA0.00046ITPKB-FALSE
chr1256510704GA0.00042RPL41+FALSE
chr186049302AG0.00114CYR61+FALSE
chr136642420TC0.00162MAP7D1+FALSE
chr399515750AG2.61553E-11MIR548G-FALSE
chr1757281021AG1.37320E-05PRR11+TRUEAluSzSINE,Alu
chr10102121601AG0.00000SCD+TRUEMLT1LSINE,Alu
chr120976759CT2.31016E-05PINK1,PINK1-AS+,-FALSE
chr110517306TC0.00176.FALSEAluJrSINE,Alu
chr116344402GA0.00168HSPB7-FALSEL3SINE,Alu
chr456295161TA0.00075CLOCK-FALSE(T)nSINE,Alu
chr239010088AG0.00192.FALSEAluSpSINE,Alu
chr138463504CT0.00068FHL3-FALSE
chr270316299CA0.00650PCBP1+FALSE
chr165897981GA0.00025LEPR,LEPROT+FALSE
chr1145324364CG0.00343NBPF20,NBPF10+FALSE
chr1241796949GA0.00053OPN3,CHML-FALSE
chr194352570GT0.00097GCLM-FALSEAluSx1SINE,Alu
chr1144606996GC0.00107NBPF20+FALSE
chr120977748TG0.00474PINK1,PINK1-AS+,-FALSE
chr1959095456AG0.00125CENPBD1P1+TRUEAluJbSINE,Alu
chr185785557TA0.00141DDAH1-FALSE
chr3184429718AG0.00914MAGEF1-FALSE
chr1144822294GC0.00371NBPF20,NBPF9+FALSE
chr1160966301TC8.33949E-06F11R-TRUEAluSgSINE,Alu
chr5115428334GT0.00265COMMD10+FALSE
chr75085646CT0.00168RBAK-RBAKDN,RBAK+FALSE
chr1162494683GT0.00269UHMK1+FALSEAluSg4SINE,Alu
chr126840209GA0.00820COPS7A+FALSE
chr16582498TC0.00403NOL9-TRUEAluSx1SINE,Alu
chr131342374AC0.00446SDC3-FALSE(A)nSINE,Alu
chr8145159707GC0.00158MAF1+FALSE
chr11252468TC0.00182CPSF3L-TRUEAluJrSINE,Alu
chr3195964298AG0.00263.FALSE
chr1747007752AT0.00029SNF8-FALSE
chr1911560438AG7.61449E-05PRKCSH+FALSEAluSxSINE,Alu
chr362282907CT9.50704E-05PTPRG-AS1-FALSE
chr179108421AT7.77428E-05IFI44L+FALSE
chr2237035915CG0.00348AGAP1+FALSE
chr154382632TC0.00219.FALSEAluSq2SINE,Alu
chr186046472GT0.00409CYR61+FALSE
chr456298300GA7.51019E-06CLOCK-FALSE
chr1160967856TC0.00027F11R-TRUEAluSpSINE,Alu
chr642855200AG2.13337E-05RPL7L1+TRUEAluSpSINE,Alu
chr138279666CT0.00521MTF1-FALSE(T)nSINE,Alu
chr1100656265CT0.00318DBT-FALSE
chr11597423CT1.10134E-13CDK11B,SLC35E2B-FALSE
chrX77083982TC0.00086MAGT1-TRUEAluSzSINE,Alu
chr2206987632TC0.00671.FALSEAluJbSINE,Alu
chr1149913513TC0.00495OTUD7B-TRUEMER96BSINE,Alu
chr5110463621GT0.00786WDR36+FALSE(T)nSINE,Alu
chr42070260GA0.00724NAT8L+FALSE(TG)nSINE,Alu
chr1919793168AG0.00481ZNF101+TRUEAluSzSINE,Alu
chr1231468953GA0.00085EXOC8-FALSE
chr13545204CG0.00829TPRG1L+FALSE
chr1174551853AC0.00079RNF169+FALSE
chr1205737665GT0.00025RAB29-FALSEAluSq2SINE,Alu
chr1957816349AG8.96695E-06.FALSEAluYSINE,Alu
chr6158613390TC0.00416GTF2H5+FALSE
chr1205739266CT0.00069RAB29-FALSE
chr126603883GA0.00660CEP85+FALSE
chr357612314TC0.00529DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr1619715543TC0.00879.FALSEAluSgSINE,Alu
chr170717293GA0.00716SRSF11+FALSE
chr116892256TC0.00370NBPF1-FALSE
chr11650657CG0.00379CDK11B,CDK11A-FALSE
chr238522138GT8.89010E-06ATL2-FALSE
chr1153907287GC0.00122DENND4B-FALSE(CTG)nSINE,Alu
chr596372165GA0.00149.FALSE
chr121779925TG0.00860NBPF3+FALSEERVL-E-intSINE,Alu
chr119586135CT0.00063MRTO4+FALSE
chr9114696428GT0.00163UGCG+FALSE(TGTTTTT)nSINE,Alu
chr126601329CT3.97278E-05MRPL51-FALSE
chr1146627405CG0.00074PRKAB2-FALSE
chr1331033325CA0.00792HMGB1-FALSE
chr43242223GA0.00073HTT+FALSE
chr1230416412CG0.00514GALNT2+FALSE
chr794060363TG2.98576E-06COL1A2+FALSE
chr11597403CT0.00912CDK11B,SLC35E2B-FALSE
chr3156258283TC0.00686SSR3-TRUEAluYk3SINE,Alu
chr1120165040TC0.00107ZNF697-FALSE
chr1013320123CA0.00830PHYH-FALSE
chr192975244TA0.00220EVI5-FALSE
chr653363497AG0.00106GCLC-FALSE
chr11252184AG0.00778CPSF3L-FALSEAluSxSINE,Alu
chr3119212010AG0.00685POGLUT1+FALSE
chr291847976CT0.00010.FALSETAR1SINE,Alu
chr1064911911AG0.00908NRBF2+FALSE
chr1757281125AG0.00204PRR11+TRUEAluSzSINE,Alu
chr1145291217CT0.00415NBPF20+FALSE
chr226617209AG5.06124E-05EPT1+FALSEAluSzSINE,Alu
chr126143727AT0.00917SEPN1+FALSEAluSxSINE,Alu
chr811700737TC0.00126CTSB-TRUEAluSgSINE,Alu
chr3197400501CG0.00270RUBCN-FALSE
chr1212277616CT0.00248DTL+FALSE

Differential Expression Gene Analysis