Dataset Overview
RBPAKAP1
Knock-MethodshRNA
RBP FamilyTUDOR
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR016IDR
PlatformHiSeq
Pubmed ID32252787

AKAP1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of AKAP1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of AKAP1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr410076959CG6.37978E-10WDR1-FALSE
chr219908316CT0.00719TEKT4P2-FALSE
chr13730332TC6.29937E-05CEP104-TRUEAluSx3SINE,Alu
chr185278665AG0.00242.FALSE
chr1109476363AG0.00172GPSM2,CLCC1+,-FALSE
chr119542401TC0.00071LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr237331277TC0.00366.FALSEAluSx1SINE,Alu
chr1145513051AG0.00269NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1145689537AG0.00028NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr116928622CA0.00197NBPF1-FALSE
chr1321547679AG0.00233LATS2-FALSE
chr194351065AT0.00142GCLM-FALSE
chr145976269CG0.00039MMACHC+FALSE
chr246414708GA0.00155PRKCE+FALSE
chr1475202288CT0.00706FCF1+FALSEAluScSINE,Alu
chr1179055020CT0.00738TOR3A+FALSE
chr110517623TC0.00348.FALSEAluSx1SINE,Alu
chr29629954TC0.00308ADAM17-FALSE
chr1156044222GT0.00037MEX3A-FALSE(T)nSINE,Alu
chr1646831408TC0.00852.FALSEAluSzSINE,Alu
chr110520725TC0.00795DFFA-TRUEAluSc8SINE,Alu
chr1168218522AG0.00153.FALSEAluSzSINE,Alu
chr1148241546GA0.00416NBPF8-FALSEU1SINE,Alu
chr1145511983AG0.00596NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr537290492TC8.25709E-07.FALSEAluSzSINE,Alu
chr1145273302AG0.00504NBPF20,NOTCH2NL+FALSE
chr159142713TC0.00078MYSM1-FALSE
chr339453160GA0.00000RPSA+FALSE
chr1150939883AG0.00472CERS2-FALSE
chr352028445CT0.00934RPL29-FALSE
chr12123253711AG0.00066DENR+TRUE(AT)nSINE,Alu
chr1204096630TC0.00471SOX13+FALSE
chr5125961810AG3.92353E-06PHAX+TRUEFLAM_CSINE,Alu
chr140147817CA0.00982HPCAL4-FALSE
chr16582558TC0.00479NOL9-TRUEAluSx1SINE,Alu
chr1121133392TC0.00651SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr473957426GT0.00434ANKRD17-FALSE
chr1569983GA0.00076.FALSE
chr345960578GA0.00632FYCO1-FALSE
chr11684346GC0.00504NADK-FALSE
chr568850922GC0.00323OCLN+FALSEAluSx4SINE,Alu
chr1117531096CT0.00168PTGFRN+FALSE
chr136068052GT1.43241E-12PSMB2-FALSEL1ME4bSINE,Alu
chr113942884AC0.00016PDPN+FALSE
chr1110596569GA0.00867STRIP1+FALSE
chr154563156AG3.59804E-06TCEANC2+FALSE
chr139990456GA0.00749BMP8A,PPIEL+,-FALSEL2bSINE,Alu
chr116890639CT0.00095NBPF1-FALSE
chr766105163CG0.00594KCTD7+FALSE
chr11246978AT0.00760PUSL1,CPSF3L+,-FALSE
chr59549459AG0.00783SNHG18+FALSE
chr2206987597TC0.00085.FALSEAluJbSINE,Alu
chr357612973TC0.00135DENND6A,PDE12+,-FALSEAluSzSINE,Alu
chr255516911AG0.00719CCDC88A-FALSE(GA)nSINE,Alu
chr1201438096GT1.87636E-05PHLDA3-FALSE
chr717384437AG0.00192AHR+TRUEAluSxSINE,Alu
chr1988503AT8.91206E-06AGRN+FALSE
chr8144357975CT0.00444GLI4+FALSE
chr110521254TC0.00856DFFA-TRUEAluYSINE,Alu
chr19163839AG0.00237.FALSE
chr765844062TA0.00733LINC00174-FALSE
chr791742142CA0.00478CYP51A1-FALSEAluSx3SINE,Alu
chr1774556011AG0.00819SNHG16+TRUEAluSq2SINE,Alu
chr1988503AT0.00402AGRN+FALSE
chr2217366192TA0.00067.FALSE
chr1168522907TC0.00828CPT1A-TRUEAluYSINE,Alu
chr186049361AG0.00036CYR61+FALSE
chr811700373TC0.00212CTSB-TRUEAluSq2SINE,Alu
chr139305021GT0.00027RRAGC-FALSE
chr1266546100AG0.00849TMBIM4-FALSE
chr353220215GA2.78975E-05PRKCD+FALSE
chr147717189AG0.00384STIL-FALSE
chr5141691252TC0.00596SPRY4-FALSE
chr1153507108AG2.72071E-06S100A6-FALSE
chr1148556107AT0.00288.FALSE
chr72294401AG0.00035SNX8-FALSE
chr11251631TC0.00256CPSF3L-TRUEAluSzSINE,Alu
chr116932931CA0.00169NBPF1-FALSEL1MC2SINE,Alu
chr1117618067CT0.00118TTF2+FALSE
chr1158424898GA0.00153.FALSE
chr895804469AG0.00133DPY19L4+TRUEAluSq2SINE,Alu
chr536143392CT0.00625LMBRD2-FALSE
chr898736864TA0.00086MTDH+FALSE
chr42517223AG2.74855E-08RNF4+FALSE
chr611185161CT0.00297NEDD9-FALSE
chr1757279257AG0.00077PRR11+TRUEAluSq2SINE,Alu
chr11252221TC0.00186CPSF3L-TRUEAluSxSINE,Alu
chr891637754AT0.00297TMEM64-FALSE
chr1833831189CA0.00763MOCOS+FALSE
chr119586501AG0.00019MRTO4+TRUEAluSzSINE,Alu
chr127205359TC3.58613E-05.FALSEAluScSINE,Alu
chr1149783886CT0.00526HIST2H2BF-FALSE
chr333186111TC0.00349CRTAP+FALSELTR16A1SINE,Alu
chr116890644CT0.00174NBPF1-FALSE
chr9136209400AG0.00328MED22-FALSE
chr417802919TC0.00857DCAF16-TRUEAluSzSINE,Alu
chr1145512024AG0.00836NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr342826041TG5.78537E-12HIGD1A-FALSE
chr634231288AG0.00143.FALSE
chr11252443TC8.33820E-06CPSF3L-TRUEAluJrSINE,Alu
chr153291435AG0.00790ZYG11B+TRUEAluJrSINE,Alu
chr3124488267GA3.46260E-06ITGB5-FALSE
chr1075008731TC8.90942E-06DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr1900721TC0.00109KLHL17+FALSE(TTTA)nSINE,Alu
chr3195395399GA0.00556SDHAP2+FALSE
chr9125609940TA0.00044.FALSE
chr345960556CT0.00500FYCO1-FALSE
chr2131906031CT0.00439PLEKHB2+FALSE
chr1186390303AC0.00455C1orf27+FALSEL1ME3FSINE,Alu
chr457327017AG4.29594E-07PAICS+TRUEAluSx1SINE,Alu
chr1160966353TC0.00011F11R-TRUEAluSgSINE,Alu
chr197543764CT0.00353DPYD-FALSE
chr3121435624CT0.00063GOLGB1-FALSE
chr1132125961CT0.00118RCN1+FALSE
chr7152345392TC0.00643XRCC2-TRUEAluSx1SINE,Alu
chr1109475543AG0.00325GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr11768386TC0.00208PDDC1-TRUEAluScSINE,Alu
chr9125887703AC0.00067STRBP-FALSE
chr1109818160TG3.82986E-06CELSR2+FALSE
chr110519936TC0.00029.FALSEAluJrSINE,Alu
chr1675479250TC0.00568TMEM170A-TRUEAluJbSINE,Alu
chr345960557CT1.72644E-06FYCO1-FALSE
chr237327685TC6.61966E-05.FALSE
chr116889217GC0.00696NBPF1-FALSEL1MC4SINE,Alu
chr151873951GA0.00591EPS15-FALSE
chr1244181367GA0.00608IRAK4+FALSEMLT1E1ASINE,Alu
chr13731959CT0.00089CEP104-FALSE
chr17421931TC0.00260VPS53-TRUEAluSxSINE,Alu
chr1154128836AT0.00090TPM3-FALSE
chr13548832GC0.00464WRAP73-FALSE
chr1171943768GT1.87744E-06INPPL1+FALSE
chr111979815AC0.00042KIAA2013-FALSE
chr138278949CA0.00664MTF1-FALSEAluSpSINE,Alu
chrX118920477AT0.00529RPL39-FALSE
chr138463504CT0.00068FHL3-FALSE
chr314986111TC0.00000FGD5-AS1-TRUEFLAM_CSINE,Alu
chrX123045342AG0.00381XIAP+FALSE(ATAA)nSINE,Alu
chr642849616AG0.00092RPL7L1+TRUEAluSzSINE,Alu
chr39519219CT0.00146SETD5+FALSE
chr631657413TC0.00767.FALSE
chr310192747AG0.00893VHL+TRUEAluSx1SINE,Alu
chr1179070646TC0.00283ABL2-TRUEAluSzSINE,Alu
chr194335191CT0.00382DNTTIP2-FALSE
chr171531596AG1.07667E-05ZRANB2-AS1,ZRANB2+,-FALSE
chr13654747CA0.00691TP73-AS1-FALSE
chr537290493TC3.58668E-05.FALSEAluSzSINE,Alu
chr417803681TC3.85233E-06DCAF16-TRUEAluYSINE,Alu
chr136794266AG0.00141.FALSEAluJbSINE,Alu
chr1145512951AG0.00180NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr119586519AG0.00239MRTO4+TRUEAluSzSINE,Alu
chr264687777GT7.38315E-07LGALSL+FALSE
chr116929327CT5.08143E-05NBPF1-FALSEERVL-E-intSINE,Alu
chr1226333556CA0.00977ACBD3-FALSE(CAAAA)nSINE,Alu
chr110517273TC0.00583.FALSEAluJrSINE,Alu
chr1757279258AG0.00114PRR11+TRUEAluSq2SINE,Alu
chr285548074TC0.00428TGOLN2-FALSE
chr1143399198CT0.00146.FALSE
chr1145281408CT0.00087NBPF20,NOTCH2NL+FALSE
chr67289958CG0.00893SSR1-FALSE
chr2134729931AG0.00040IFNAR1+TRUEAluSg7SINE,Alu
chr8100890423CA0.00113COX6C-FALSE
chr624719384AC0.00215C6orf62-FALSE(A)nSINE,Alu
chr333038221CT0.00379GLB1-FALSE
chr136067870TC0.00513PSMB2-TRUEAluSzSINE,Alu
chr1168218494AG0.00317.FALSEAluSzSINE,Alu
chr110520058TC0.00907.FALSEAluSxSINE,Alu
chr226399214GA0.00187GAREM2+FALSE
chr534906692TC0.00021RAD1-TRUEAluJoSINE,Alu
chr114159457AG0.00764RRM1+FALSE
chr5175816759TA0.00018.FALSE
chr13114204255AG0.00134TMCO3+FALSE
chr11252441TC0.00602CPSF3L-TRUEAluJrSINE,Alu
chr210942687CT0.00082PDIA6-FALSE
chr2101635538CT0.00069TBC1D8,RPL31+,-FALSECharlie17SINE,Alu
chr11255402CG0.00785CPSF3L-FALSE(GCAGG)nSINE,Alu
chr237478348TA0.00392PRKD3-FALSE
chr483406544CT0.00328TMEM150C-FALSE
chr16282295TC0.00060ICMT-TRUEAluSzSINE,Alu
chr1204525649AG0.00191MDM4+TRUEAluSzSINE,Alu
chr1110913120CT0.00627SLC16A4-FALSE
chr1154554945AG0.00877ADAR-FALSE
chr120976023TC6.30669E-06PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1110136846TA0.00639GNAI3+FALSE
chr116889866GA0.00995NBPF1-FALSE
chr5145666109AT0.00728RBM27+FALSE
chr1100615003GA0.00046TRMT13,LRRC39+,-FALSE
chr1145511796TG0.00173NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSE(T)nSINE,Alu
chr115993013GA1.16652E-10.FALSE
chr178187733GA0.00388USP33-FALSE
chr1145513017AG0.00142NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr417803616TC1.55934E-06DCAF16-TRUEAluYSINE,Alu
chr153680205CT4.54902E-05C1orf123-FALSE
chr837613073AC0.00394ERLIN2+FALSE(CCCCCAC)nSINE,Alu
chr143916642TC0.00748SZT2+FALSEMIR3SINE,Alu
chr1542859452AG0.00123HAUS2+TRUEAluJbSINE,Alu
chr364081236TC8.95068E-05PRICKLE2,PRICKLE2-AS1+,-FALSE
chr537290435TC8.22232E-07.FALSEAluSzSINE,Alu
chr2209180073CA0.00478PIKFYVE+FALSE
chr144072018CT0.00160PTPRF+FALSE
chr345721989AG0.00713LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr63021360TC0.00321HTATSF1P2-TRUEAluJr4SINE,Alu
chr1954627915CT0.00015PRPF31+FALSE
chr1590375419TC0.00521C15orf38-AP3S2,AP3S2-TRUEAluJrSINE,Alu
chr1918475356AG0.00360PGPEP1+TRUEAluSx1SINE,Alu
chr1193054575CG0.00029TROVE2+FALSE(ATTTT)nSINE,Alu
chr136534830AG0.00470.FALSEAluJoSINE,Alu
chr744917278TC0.00461PURB-TRUEAluSzSINE,Alu
chr1022825288GA0.00051PIP4K2A-FALSE
chr140537937AC0.00091CAP1+FALSE(A)nSINE,Alu
chr1565442476TC0.00084CLPX-TRUEAluSg4SINE,Alu
chr119585519AG3.44907E-05MRTO4+TRUEAluSc8SINE,Alu
chr3183209065TC0.00576KLHL6-TRUEAluSqSINE,Alu
chr1229736656GC0.00793TAF5L-FALSE
chr13753136AT0.00088CEP104-FALSE
chr46304286CT0.00054WFS1+FALSE
chr7131241049GA0.00145PODXL-FALSE(GGCGAC)nSINE,Alu
chr1179326847AG0.00577SOAT1+TRUEAluJoSINE,Alu
chr1569803GA0.00695.FALSE
chr410443062TG0.00303ZNF518B-FALSE
chr116945409TA0.00105CROCCP2-FALSE
chr274333232CT0.00274TET3+FALSE
chr2204301752GC0.00029RAPH1-FALSE
chr3155572129CT0.00082SLC33A1-FALSE
chr1144619903TA0.00712NBPF20,NBPF9+FALSE
chr1231154918GT0.00022FAM89A-FALSE(T)nSINE,Alu
chr775958151GC0.00250YWHAG-FALSE
chr127332852CT0.00829FAM46B-FALSE
chr116890130AC0.00753NBPF1-FALSE
chr1110912873TC0.00116SLC16A4-FALSE
chr456295161TA0.00075CLOCK-FALSE(T)nSINE,Alu
chr830643549GC0.00257PPP2CB-FALSE
chr136068237TC0.00291PSMB2-TRUEAluScSINE,Alu
chr2134728175AG6.62284E-07IFNAR1+TRUEAluScSINE,Alu
chr1155734530TC0.00214GON4L-TRUE
chr439550084TC2.47241E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr338296817GA3.46922E-11OXSR1+FALSE
chr11661751AG0.00037SLC35E2-FALSE
chr41982726CT0.00828WHSC1+FALSE
chr135223881GA0.00228GJB5+FALSE
chr357612180TC0.00018DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr167451522AT0.00949MIER1+FALSE
chr211323078CT0.00539ROCK2-FALSE
chr2128602507TC4.02376E-05.FALSEAluSq2SINE,Alu
chr340578815AG0.00041ZNF621+FALSEAluJrSINE,Alu
chr1214524129TC0.00052PTPN14-TRUEAluSxSINE,Alu
chr1145282799GA0.00915NBPF20,NOTCH2NL+FALSE
chr16651457GA0.00614KLHL21-FALSE
chr7937828GA0.00605ADAP1-FALSE
chr9115446725TC0.00917INIP-TRUEAluJrSINE,Alu
chr154412181TC0.00524LRRC42+FALSE
chr537290397TC0.00305.FALSEAluSzSINE,Alu
chr170904800GT0.00020CTH+FALSE
chr286252198TC0.00076POLR1A-TRUEAluSq2SINE,Alu
chr1590815787AG0.00055.FALSEFRAMSINE,Alu
chr153288924AG0.00099ZYG11B+TRUEAluJoSINE,Alu
chr1120839682AG0.00073FAM72B+FALSE
chr19161245TC0.00071.FALSEAluSxSINE,Alu
chr1120163247TC0.00365ZNF697-FALSE
chr16283348TC0.00247ICMT-TRUEAluSx3SINE,Alu
chr116890598TA0.00428NBPF1-FALSE
chr1146643580GA0.00113PRKAB2-FALSE
chr16283306TC0.00275ICMT-TRUEAluSx3SINE,Alu
chr7156763172AG0.00874NOM1+TRUEAluSxSINE,Alu
chr1212277584GC0.00997DTL+FALSE
chr16283434TC4.87712E-06ICMT-TRUEAluSx3SINE,Alu
chr237331555TC0.00171.FALSEAluJbSINE,Alu
chr2114352238GA8.42668E-06WASH2P+FALSE
chr1150937963AG0.00658CERS2-FALSEG-richSINE,Alu
chr1156011444TC0.00483UBQLN4-FALSE
chr320195395CT3.65176E-06KAT2B+FALSE
chr6134492481AC0.00340SGK1-FALSE
chr1154557171GA0.00045ADAR-FALSEA-richSINE,Alu
chr136535560AG0.00059.FALSEAluSx1SINE,Alu
chr5154196577CT0.00906LARP1+FALSE
chr2128063697GA0.00775MAP3K2-FALSE
chr417804740TC0.00015DCAF16-TRUEAluSxSINE,Alu
chr11252723TC7.44553E-05CPSF3L-TRUEAluSpSINE,Alu
chr1200521297CT0.00133KIF14-FALSE(T)nSINE,Alu
chr2109301115TA0.00150LIMS1+FALSE
chr537290416TC0.00162.FALSEAluSzSINE,Alu
chr111347154AT0.00366UBIAD1+FALSE
chr1120612154CG0.00803NOTCH2-FALSE
chr146660295TC0.00871POMGNT1-FALSE
chr132385071TA0.00436PTP4A2-FALSE
chr1610624953TC0.00056EMP2-TRUEAluSx3SINE,Alu
chr3172117457CA0.00037FNDC3B+FALSE
chr2025428308AG0.00185GINS1+TRUEAluSzSINE,Alu
chr131905905GC0.00948SERINC2+FALSE
chr3120113403TG2.55249E-11FSTL1-FALSE
chr455147769CT0.00079PDGFRA+FALSE
chr1144822330CT6.80810E-06NBPF20,NBPF9+FALSE
chr126673076GA0.00465AIM1L-FALSE
chr116932144AC7.50683E-06NBPF1-FALSE
chr4156273768TC0.00058MAP9-FALSE
chr13416449CA0.00748MEGF6-FALSE
chr67250960GA0.00889RREB1+FALSE
chr1492585231TC0.00023NDUFB1-TRUEAluSgSINE,Alu
chr2054963816TC0.00750AURKA-TRUEAluSq10SINE,Alu
chr593018884AC0.00030FAM172A-FALSE(TCA)nSINE,Alu
chr110520296TC0.00299.FALSEAluSxSINE,Alu
chr347953733CA0.00057MAP4-FALSE
chr116889864CA0.00598NBPF1-FALSE
chr228635740TC0.00358FOSL2+FALSE
chr1148252049AC0.00666NBPF8,NBPF14,NBPF9-FALSE
chr11126147713CG0.00384FOXRED1+FALSE
chr147184569GC0.00509EFCAB14-FALSE
chr237328097TC0.00091.FALSE
chr110521172TC1.01590E-06DFFA-TRUEAluYSINE,Alu
chr552250837CT0.00017.FALSE
chr29630247TG0.00638ADAM17-FALSE
chr6143382534CT0.00252AIG1+FALSE
chr146782446AG0.00145UQCRH+FALSE
chr187811100AT0.00084LMO4+FALSE
chr417803545TC0.00710DCAF16-TRUEAluYSINE,Alu
chr3169810385CT0.00621PHC3-FALSE
chr116891340TA0.00022NBPF1-FALSE
chr1156613517CA0.00011BCAN+FALSE
chr228639641CG0.00431.FALSE
chr12120899168AG6.24570E-05GATC+TRUEAluJrSINE,Alu
chr2206982257TC0.00023.FALSEAluSg7SINE,Alu
chr1112266787GT0.00642FAM212B-FALSE
chr1145281656AT0.00202NBPF20,NOTCH2NL+FALSE
chr1148595665AG0.00378NBPF15+TRUEL1MC4SINE,Alu
chr186049392CA0.00322CYR61+FALSE
chr126898378CA0.00148RPS6KA1+FALSE

Differential Expression Gene Analysis