Dataset Overview
RBPPRPF4
Knock-MethodshRNA
RBP FamilyPRP4
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR215FRI
PlatformHiSeq
Pubmed ID32252787

PRPF4 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PRPF4
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PRPF4


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr316357708AG0.00098RFTN1-FALSE
chr1246829616TC0.00029CNST+FALSE
chr811700444CG0.00042CTSB-FALSEAluSq2SINE,Alu
chr2203742188TC0.00522.FALSEAluJbSINE,Alu
chr1144931330CT0.00295NBPF20,PDE4DIP+,-FALSE
chr153291425AG0.00507ZYG11B+TRUEAluJrSINE,Alu
chr2109301115TA0.00150LIMS1+FALSE
chr167874859TC1.49998E-05SERBP1-TRUEAluSxSINE,Alu
chrX123046741AG0.00169XIAP+TRUEAluSzSINE,Alu
chr2176789423CA0.00441LNPK-FALSEMSTB1SINE,Alu
chr121086062GT0.00847RAD52-FALSEL2SINE,Alu
chr187213188CA0.00236SH3GLB1+FALSE
chr2029631604GA0.00045FRG1BP+FALSE
chr1177976440CT0.00148LOC730102-FALSE
chr298089475TA0.00385LOC100506076,LOC100506123-FALSE
chr146269493GC0.00233MAST2+FALSE
chr2035520976TC0.00254TLDC2,SAMHD1+,-FALSEFLAM_ASINE,Alu
chr1183876182CT0.00494RGL1+FALSE
chr3100119819CT0.00850TOMM70-FALSE
chr142886523TC0.00649RIMKLA+FALSEMIRcSINE,Alu
chr286249961TC0.00292LOC90784-TRUEAluJrSINE,Alu
chr2143638994GA0.00075KYNU+FALSE
chr29630248GT0.00764ADAM17-FALSE
chr1145512944AG0.00110NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1145100772AG0.00945NBPF20,SEC22B+TRUEAluSg4SINE,Alu
chr3149237753GA2.17555E-05WWTR1-FALSEAluSq2SINE,Alu
chr716640491GA0.00478ANKMY2-FALSE
chr116890639CT5.60894E-05NBPF1-FALSE
chr2191067763AT0.00038C2orf88+FALSE
chr45743512TC0.00045EVC+FALSE
chr1118068558GA0.00644.FALSE
chr553840199GT0.00857SNX18+FALSE
chr1946214293CT0.00137FBXO46-FALSE
chr165690461GA0.00115AK4+FALSE
chr642060429TC0.00017.FALSEAluSz6SINE,Alu
chr9137330709GT6.64722E-05RXRA+FALSE(GCTG)nSINE,Alu
chr190470915TA9.94810E-07ZNF326+FALSE
chr2191745647CT2.95764E-05GLS+FALSE
chr12326812AG0.00709RER1+FALSE
chr4128757415AG0.00367.FALSEAluYSINE,Alu
chr140537947AC0.00295CAP1+FALSE
chr16311399AG0.00126GPR153-FALSE
chr187573331TC0.00699HS2ST1+FALSE(AT)nSINE,Alu
chr1156219450AG0.00753SMG5-FALSE
chr146076529AG0.00196NASP+TRUEAluSxSINE,Alu
chr3101546847GA0.00665NXPE3,NFKBIZ+FALSE
chr340503554AC0.00197RPL14+FALSE
chr1675479910TC0.00026TMEM170A-TRUEAluSg4SINE,Alu
chr136642420TC0.00162MAP7D1+FALSE
chr1143189473CA0.00572LOC102723769-FALSE
chr110521130TC1.15946E-05DFFA-TRUEAluYSINE,Alu
chr116890130AC0.00412NBPF1-FALSE
chr133147947AG0.00345SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr7100958270TC0.00087LOC101927746,IFT22+,-FALSE
chr7128143932AG0.00332.FALSEAluSq2SINE,Alu
chr6114182271GA0.00011MARCKS+FALSE
chr11118471800TA0.00875ARCN1+FALSEAluSx3SINE,Alu
chr110517273TC0.00583.FALSEAluJrSINE,Alu
chr12125627187CT0.00055AACS+FALSE
chr1145292925CT0.00817NBPF20+FALSE
chr9115447533TC0.00326INIP-TRUEAluJbSINE,Alu
chr438945689CT1.01800E-05FAM114A1+FALSEAluScSINE,Alu
chr153289852AG0.00020ZYG11B+TRUEFRAMSINE,Alu
chr2109401286GT0.00087RANBP2+FALSE
chr237331065TC0.00527.FALSEAluSx1SINE,Alu
chr185786299TA0.00502DDAH1-FALSE
chr1145693061AG0.00158NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr1155181396AG0.00209MTX1+FALSE
chr23592615TC0.00331RNASEH1-TRUEAluSz6SINE,Alu
chr1585185205TC0.00459WDR73,SCAND2P+,-FALSEFLAM_CSINE,Alu
chr118707394TA4.23595E-06RPL27A+FALSE
chr120519965GT0.00011UBXN10+FALSE
chr729961437TG6.91541E-06SCRN1-FALSE
chr2217366499AG0.00183.FALSEAluSzSINE,Alu
chr116258610CG0.00142SPEN+FALSE
chr5159829024GC0.00400SLU7-FALSE
chr1208198625CT8.83580E-05PLXNA2-FALSE
chr237328013TC1.05952E-05.FALSE
chr2114356360GA0.00520WASH2P+FALSE
chr158999651TG0.00332OMA1-FALSE
chr2202083872AG0.00022CASP10+TRUEAluSzSINE,Alu
chr1145511796TG0.00428NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSE(T)nSINE,Alu
chr348787684TC0.00813PRKAR2A-TRUEAluSpSINE,Alu
chr116928737CT0.00448NBPF1-FALSEERVL-E-intSINE,Alu
chr2174090339AC2.67746E-05ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr119578576GA0.00347MRTO4+FALSE
chr177165735AG0.00227.FALSE
chr633172015TC5.04816E-05.FALSE
chr1148558170TC0.00235.FALSEAluJbSINE,Alu
chr2207027628AG0.00022EEF1B2+FALSE
chr237328075TC0.00863.FALSE
chr125717365CG0.00229RHCE-FALSE
chr1142688597CT0.00605.FALSE
chr5149829076GC0.00288RPS14-FALSE
chr1228881129AG0.00199RHOU+FALSE
chr352873072AC0.00233TMEM110-MUSTN1,TMEM110-FALSE
chr425253995CT9.95051E-10PI4K2B+FALSE
chr111783009AG7.55078E-05.FALSEAluSxSINE,Alu
chr5151041877CA1.29615E-05SPARC-FALSE
chr1247319705TG6.58458E-05ZNF124-FALSE
chr1204525667AG3.94227E-05MDM4+TRUEAluSzSINE,Alu
chr417802931TC0.00951DCAF16-TRUEAluSzSINE,Alu
chr552389815AG0.00486ITGA2+TRUE
chr348787640TC0.00320PRKAR2A-TRUEAluSpSINE,Alu
chr348787715TC0.00863PRKAR2A-TRUEAluSpSINE,Alu
chr1585184816TC3.05793E-06WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr315114293TC2.60553E-05RBSN-TRUEAluYSINE,Alu
chr152375424TC0.00109RAB3B-FALSE
chr6160526904TG0.00027IGF2R+FALSE
chr439528976CT8.52335E-05UGDH-FALSE
chr126774224AG0.00349DHDDS+TRUEAluSz6SINE,Alu
chr18938808CA0.00030ENO1-FALSE
chr1998582GC0.00073.FALSE
chr299772827AG0.00108LIPT1+TRUEAluSx1SINE,Alu
chr116889414TC0.00384NBPF1-TRUEL1MC4SINE,Alu
chr2018468404TC0.00301RBBP9-TRUEAluSz6SINE,Alu
chr2202030111AG0.00983CFLAR+TRUEAluSx1SINE,Alu
chr11118888992CG0.00222RPS25-FALSE
chr1236717926TC0.00029HEATR1-FALSE
chr11325721CT0.00471CCNL2-FALSE
chr1913884096AG1.54361E-06MRI1+TRUEAluSzSINE,Alu
chr255459820CT0.00714RPS27A+FALSE
chr1773886219TC8.52474E-05TRIM65-TRUEFRAMSINE,Alu
chr127861184GT0.00425AHDC1-FALSE(TCTTTT)nSINE,Alu
chr12123253851AG0.00470DENR+FALSE(AT)nSINE,Alu
chrX54587254AG0.00019GNL3L+TRUEAluSq2SINE,Alu
chr2128063526CA0.00759MAP3K2-FALSE
chr138158211CT0.00113CDCA8+FALSE
chr1923926877AT0.00896ZNF681-FALSE
chr11421531CA0.00409ATAD3B+FALSE
chr9115936771CT1.86133E-10FKBP15-FALSE
chr12125114CT8.70493E-12FAAP20-FALSE
chr11345006AG0.00123.FALSEAluSgSINE,Alu
chr349394834GA0.00000GPX1-FALSE
chr2183817957TA0.00031NCKAP1-FALSE
chr7143003526AT0.00050CASP2+FALSEAluYSINE,Alu
chr1542550349AC0.00120TMEM87A-FALSE
chr1146649940CT1.24118E-05PDIA3P1+FALSE
chr19161231TC0.00481.FALSEAluSxSINE,Alu
chr255462751TA0.00613RPS27A+FALSE
chr1108742130TC1.29742E-06SLC25A24-FALSE
chr1179326295AG0.00035SOAT1+TRUE
chr153291382AG0.00691ZYG11B+TRUEAluJrSINE,Alu
chr568788642GC3.71778E-05OCLN+FALSE
chr1145512073AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr110044137AG2.83529E-05NMNAT1+TRUEAluSx1SINE,Alu
chr1206579936AG0.00974SRGAP2+FALSE
chr1451387782CT0.00802PYGL-FALSE
chr124796838AG0.00484NIPAL3+FALSEMER5ASINE,Alu
chr1810691357GA0.00082PIEZO2-FALSE
chr128662186AG0.00774MED18+TRUEAluSq2SINE,Alu
chr1463841402AC0.00692PPP2R5E-FALSE
chr3194361768CT1.49766E-06LSG1-FALSEMSTASINE,Alu
chr1749042386TC4.28426E-05SPAG9-TRUEAluJbSINE,Alu
chr16582353TC0.00121NOL9-TRUEAluSx1SINE,Alu
chr119586532AG0.00769MRTO4+TRUEAluSzSINE,Alu
chr1523283141CA0.00056HERC2P2-FALSE
chr116889820CT0.00709NBPF1-FALSE
chr190478690AC0.00035ZNF326+FALSE
chr11458255TG0.00438ATAD3A+FALSE
chr153289860AG0.00041ZYG11B+TRUEFRAMSINE,Alu
chr110520202TC0.00529.FALSEAluSxSINE,Alu
chr1204524357AG0.00568MDM4+TRUEAluYSINE,Alu
chr19910357AT0.00056CTNNBIP1-FALSE
chr237331555TC0.00992.FALSEAluJbSINE,Alu
chr514510067GT0.00130TRIO+FALSE
chr2152334389AG0.00308.FALSEAluSqSINE,Alu
chr256150885GA0.00624EFEMP1-FALSE
chr1540712737TC0.00525IVD+FALSE
chr2218571345AG0.00113PEX26+TRUEAluSzSINE,Alu
chr439550549TC0.00014UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr237329347TC0.00155.FALSEAluJr4SINE,Alu
chr116945227GT0.00090CROCCP2-FALSE
chr110042987AG3.47016E-05NMNAT1+TRUEAluScSINE,Alu
chr3156259229TC0.00225SSR3-TRUEAluSq2SINE,Alu
chr116112795AG0.00499FBLIM1+FALSE
chr765844062TA0.00733LINC00174-FALSE
chr1145293059AG0.00063NBPF20+FALSE
chr132508397TC0.00166KHDRBS1+FALSE
chr136067817TC7.91657E-05PSMB2-TRUEAluSzSINE,Alu
chr1226923938AC0.00160ITPKB-FALSE
chr8144940792GC9.20360E-05EPPK1-FALSE
chr167875011GT0.00359SERBP1-FALSE
chr126143698TA0.00832SEPN1+FALSE
chr1088951001GA0.00033FAM35A+FALSE
chr830536410TC3.13735E-05GSR-TRUEAluSpSINE,Alu
chr2035409827TC0.00267SOGA1-TRUEAluSxSINE,Alu
chr18412989AG0.00225RERE-FALSE
chr1161160459TC0.00270ADAMTS4-FALSE(CA)nSINE,Alu
chr116891365GA0.00475NBPF1-FALSE
chr35260057AT0.00117EDEM1+FALSE
chr7100072031TC0.00238TSC22D4-FALSE
chr132833540TC0.00381BSDC1-TRUE
chr164095111AG0.00201PGM1+FALSE
chr2101622881CA1.48865E-05RPL31+FALSE
chr2144331206AG0.00167.FALSEAluSzSINE,Alu
chr1945406537TC0.00278TOMM40+FALSE
chr147716046AT0.00696STIL-FALSE
chr1206566904TC0.00084SRGAP2+FALSE
chr11125763746CG0.00166HYLS1,PUS3+,-FALSE
chr287777087TC0.00737LINC00152+FALSE
chr1298943011AG1.18352E-07TMPO+TRUEAluSzSINE,Alu
chr116893763TC0.00996NBPF1-FALSE
chr2128064446GT0.00652MAP3K2-FALSE(GT)nSINE,Alu
chr1110300588CT0.00232EPS8L3-FALSE
chr1144868170CT0.00750NBPF20,PDE4DIP+,-FALSE
chr1144606963GT0.00965NBPF20+FALSE
chr1912742290AG0.00564.FALSEAluSxSINE,Alu
chr11593060TC5.25946E-05CDK11B,SLC35E2B-FALSE
chr1155106550AG0.00015EFNA1+FALSE
chr1200521297CT0.00133KIF14-FALSE(T)nSINE,Alu
chr1110170896TC0.00140AMPD2+FALSE
chr2183643905AT0.00113DNAJC10+FALSE
chr11597403CT0.00912CDK11B,SLC35E2B-FALSE
chr116892256TC0.00468NBPF1-FALSE
chr1201975173GT0.00356RNPEP+FALSE
chr1757279258AG0.00114PRR11+TRUEAluSq2SINE,Alu
chr1531619607GA0.00887KLF13+FALSE
chr1298942904AG0.00259TMPO+TRUEAluScSINE,Alu
chr1251325280AG0.00370METTL7A+TRUEAluSq2SINE,Alu
chr1541591457AG1.25234E-05OIP5-AS1+TRUEAluSxSINE,Alu
chr1220870440GA0.00193C1orf115+FALSE
chr310193475AG0.00110VHL+TRUEAluJrSINE,Alu
chr352237970CT0.00017ALAS1+FALSE
chr210074384GA0.00765TAF1B+FALSE
chr1610625049TC1.15092E-05EMP2-TRUEAluSx3SINE,Alu
chr74802065CT0.00279FOXK1+FALSE
chr848890288AG0.00210MCM4+TRUEAluJbSINE,Alu
chr373025345AG0.00219.FALSEAluSzSINE,Alu
chr568858545CG0.00268GTF2H2C,GTF2H2C_2+FALSEAluSzSINE,Alu
chr1207942482AG0.00715CD46+TRUEAluSg4SINE,Alu
chr1197477932CT0.00488DENND1B-FALSE
chr2161130521GA0.00454RBMS1-FALSE
chr632148031AG1.10299E-06.FALSE
chr10104417856TA0.00616TRIM8+FALSE(AAT)nSINE,Alu
chr1206566948GA0.00568SRGAP2+FALSE
chr1951305796TC0.00212C19orf48-TRUEAluSgSINE,Alu
chr119542463TC0.00111LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr495586224AG0.00053PDLIM5+FALSE
chr2232319615AT8.19218E-06NCL-FALSE
chr1117645998AG0.00434.FALSE
chr136068370TC0.00789PSMB2-TRUEAluScSINE,Alu
chr644417159AG0.00959CDC5L+TRUEFLAM_CSINE,Alu
chr119543465TC0.00709LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr133149256AG0.00286SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr4165998078TC0.00407TMEM192-TRUEAluSxSINE,Alu
chr1186390303AC0.00455C1orf27+FALSEL1ME3FSINE,Alu
chr1113672569AG0.00742.FALSEAluJbSINE,Alu
chr233623905GT0.00262LTBP1+FALSE
chr5149829071TC0.00407RPS14-FALSE
chr136068231TC9.19439E-05PSMB2-TRUEAluScSINE,Alu
chr29558812GT0.00427ITGB1BP1-FALSE
chr3124950421TA0.00713ZNF148-FALSE
chr86263057AC0.00419LOC100287015-FALSE
chr139317318CA1.55431E-15RRAGC-FALSE
chr8144827206AT0.00196FAM83H-AS1+FALSEERVL-B4-intSINE,Alu
chr1958374130CT0.00124ZNF587+FALSE
chr224224000AG0.00464.FALSEAluSpSINE,Alu
chr1545775144TC0.00867SLC30A4-TRUEAluJrSINE,Alu
chr1921367088AG0.00018ZNF431+TRUEAluScSINE,Alu
chr1098281496TC0.00509TM9SF3-FALSE
chr199164434GA0.00309SNX7+FALSE
chr138326774TC0.00664INPP5B-TRUEAluJrSINE,Alu
chr136535560AG0.00059.FALSEAluSx1SINE,Alu
chr1144877176CT0.00010NBPF20,PDE4DIP+,-FALSE
chr11419743AG0.00848ATAD3B+TRUEAluYk2SINE,Alu
chr1153920564AG0.00057CRTC2-FALSE
chr1658054472TC0.00530USB1+FALSE
chr111979809AC0.00525KIAA2013-FALSE
chr1220231959TC1.45735E-05RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr1213069783AG0.00600FLVCR1+FALSE
chr1145284883AG0.00329NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr1179852074TC0.00033TOR1AIP1+FALSE
chr1475202512AG0.00053FCF1+TRUEAluScSINE,Alu
chr129519595TC0.00208MECR-TRUEAluJbSINE,Alu
chr132801694AC0.00847MARCKSL1-FALSE
chr3156259314TC2.71784E-05SSR3-TRUEAluSq2SINE,Alu
chr1144595886GA0.00242NBPF20+FALSEAluJbSINE,Alu
chr110519951TC0.00378.FALSEAluJrSINE,Alu
chr1114519351TG0.00773HIPK1+FALSE
chr72473747AG0.00872CHST12+FALSE(CCGC)nSINE,Alu
chr748146088AG0.00825UPP1+TRUEAluSqSINE,Alu
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr1420940606GA0.00710PNP+FALSE
chr417803568TC0.00044DCAF16-TRUEAluYSINE,Alu
chr193827764AG0.00056DR1+FALSE
chr1144615138TG0.00196NBPF20,NBPF9+FALSE
chr2174090336AC0.00331ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr193599279GA0.00849MTF2+FALSE
chr128825337AG0.00099PHACTR4+TRUEAluSgSINE,Alu
chr1146649884TA0.00338PDIA3P1+FALSE
chr1110950295CA0.00359LAMTOR5-FALSE
chr1157043632CT0.00085.FALSE
chr111846092GT0.00877C1orf167,MTHFR+,-FALSE
chr1168213597AG0.00481.FALSEAluSx1SINE,Alu
chr7100739267GA0.00654.FALSEAluSxSINE,Alu
chr116893691CA0.00371NBPF1-FALSE
chr1256510704GA0.00042RPL41+FALSE
chr132373854AT0.00096PTP4A2-FALSE
chr755433884AC0.00271LANCL2+FALSE
chr110519982TC0.00129.FALSEAluJrSINE,Alu
chr135646125CT0.00027SFPQ-FALSE
chr1173860808AG0.00042.FALSEFLAM_ASINE,Alu
chr110517659TC0.00516.FALSEAluSx1SINE,Alu
chr1900720AT0.00204KLHL17+FALSE(TTTA)nSINE,Alu
chr9131872853CG0.00108CRAT-FALSE
chr1205737665GT0.00078RAB29-FALSEAluSq2SINE,Alu
chr2183601110TG0.00824DNAJC10+FALSE
chr1942376710AG1.82395E-05.FALSEAluSpSINE,Alu
chr1179327008AG0.00168SOAT1+TRUE
chr4170678993TC3.15742E-05HPF1-FALSE
chr127678721AG0.00030SYTL1+TRUEAluSx1SINE,Alu
chr1541590999AG0.00049OIP5-AS1+TRUEAluSx1SINE,Alu
chr310065426CT0.00776CIDECP-FALSE
chr536143392CT0.00625LMBRD2-FALSE
chr1162497663GA0.00365UHMK1+FALSE
chr2192555178CT0.00112LOC105747689+FALSE
chr1757279281AG0.00918PRR11+TRUEAluSq2SINE,Alu
chr1749041692TC2.35976E-05SPAG9-TRUEAluSxSINE,Alu
chr168940566AC0.00126DEPDC1-FALSE
chr11431502GA0.00127ATAD3B+FALSE
chr9100777784TA0.00080ANP32B+FALSE
chr111084103TA0.00118TARDBP+FALSE
chr1453242354TC3.85910E-06GNPNAT1-TRUEAluJoSINE,Alu
chr237327670TC5.08697E-08.FALSE
chr674346347AG4.16931E-07SLC17A5-FALSE
chr738764358TC0.00675VPS41-TRUEAluSpSINE,Alu
chr29629298GC0.00590ADAM17-FALSE(TGT)nSINE,Alu
chr1298942820AG0.00568TMPO+TRUEAluScSINE,Alu
chr6158613390TC0.00416GTF2H5+FALSE
chr6149912307AG0.00026.FALSEAluScSINE,Alu
chr147184539CT0.00425EFCAB14-FALSE
chr229023124GT0.00477PPP1CB+FALSE
chr19331101AG3.95613E-06H6PD+FALSEAluSxSINE,Alu
chr439552646TC0.00555UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr198005999TC0.00027TIMM44-FALSE

Differential Expression Gene Analysis