Dataset Overview
RBPEXOSC9
Knock-MethodshRNA
RBP FamilyRNase_PH
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR812EIA
PlatformHiSeq
Pubmed ID32252787

EXOSC9 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EXOSC9
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EXOSC9


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1165544342TC3.74920E-05AP5B1-TRUEAluJbSINE,Alu
chr226617209AG5.06124E-05EPT1+FALSEAluSzSINE,Alu
chr1761897188GT0.00465FTSJ3-FALSE
chr2238499528TG0.00332RAB17-FALSE
chr19643195AG0.00294.FALSEAluSxSINE,Alu
chr452753346AG0.00782DCUN1D4+TRUEAluScSINE,Alu
chr1063852210CT0.00324ARID5B+FALSE
chr1269160574AG0.00891.FALSEAluJbSINE,Alu
chr2198572076AC0.00532MARS2+FALSE
chr642849746AG0.00042RPL7L1+TRUEAluSzSINE,Alu
chr119953124GA0.00137MINOS1,MINOS1-NBL1+FALSE
chr4189026673AG0.00994TRIML2-FALSE
chr6114178851TC0.00056MARCKS+FALSE(TGCCGC)nSINE,Alu
chr439289308GC0.00509RFC1-FALSE
chr116889820CT0.00012NBPF1-FALSE
chr799006740GA0.00269BUD31+FALSE
chr116912029CG0.00699NBPF1-FALSE
chr116958064AG0.00446.FALSE
chr1453109810TC0.00463ERO1A-TRUEMER53SINE,Alu
chr119984346AG0.00071MINOS1-NBL1,NBL1+FALSE
chr13730400TC0.00018CEP104-TRUEAluSx3SINE,Alu
chr153289860AG0.00346ZYG11B+TRUEFRAMSINE,Alu
chr1226333558AC0.00052ACBD3-FALSE(CAAAA)nSINE,Alu
chr46689813CA0.00141.FALSEL2bSINE,Alu
chr1071909957GT0.00853.FALSE
chr319992312AG0.00798RAB5A+FALSE
chr136067784TC0.00083PSMB2-TRUEAluSzSINE,Alu
chr116893686GC0.00823NBPF1-FALSE
chr16427820CT0.00240TMEM8A-FALSE
chr1541590932AG0.00055OIP5-AS1+TRUEAluSx1SINE,Alu
chr16283264TC0.00127ICMT-TRUEAluSx3SINE,Alu
chr564964627TC2.01273E-05SGTB-TRUEAluSx1SINE,Alu
chr5178986978CG0.00341RUFY1+FALSE
chr16651728CT0.00118KLHL21-FALSE
chr1583659319AT0.00130FAM103A1,C15orf40+,-FALSE
chr110519787AT0.00037.FALSE(A)nSINE,Alu
chr1475202532AG1.20675E-07FCF1+TRUEAluScSINE,Alu
chr5118174735TC0.00046DTWD2-TRUEAluYSINE,Alu
chr1161930908GA0.00664ATF6+FALSE
chr127879798AG0.00899AHDC1-FALSEMIRbSINE,Alu
chr116921146TC0.00353NBPF1-FALSE
chr167874697TC0.00642SERBP1-TRUEAluSx3SINE,Alu
chr456237899AG0.00503SRD5A3,SRD5A3-AS1+,-FALSEAluSxSINE,Alu
chr11607574CT0.00187CDK11B,SLC35E2B-FALSE
chr19910358TC0.00083CTNNBIP1-FALSE
chr19163110TC4.21626E-05.FALSEFRAMSINE,Alu
chr1946053370TC0.00045OPA3-TRUEAluSx1SINE,Alu
chr2202032184AG0.00954CFLAR+FALSEAluJoSINE,Alu
chr5177576461AT0.00659.FALSE
chr44291825CT1.35815E-09LYAR-FALSE
chr115755550AC0.00969EFHD2+FALSE
chr110521254TC0.00023DFFA-TRUEAluYSINE,Alu
chr136067677TC5.01583E-07PSMB2-TRUEAluSzSINE,Alu
chr332567573GA0.00701DYNC1LI1-FALSE(AT)nSINE,Alu
chr1350487353TC0.00538SPRYD7-TRUEAluSgSINE,Alu
chr579923424TC0.00054DHFR-TRUEAluJrSINE,Alu
chr164810507GA0.00021ZNF500-FALSE
chr744918732TC0.00039PURB-FALSEAluSgSINE,Alu
chr314526625TG0.00414SLC6A6+FALSE
chr310143199AG0.00496FANCD2,FANCD2OS+,-FALSEAluSc8SINE,Alu
chr631595882CA0.00450.FALSE
chr146075189CA0.00597NASP+FALSEA-richSINE,Alu
chr3127790249AG0.00276RUVBL1,SEC61A1+,-FALSE
chr1109181308TA0.00756FAM102B+FALSE
chr1346700519CA0.00089LCP1-FALSE
chr16475348CA4.73725E-05HES2-FALSETigger1SINE,Alu
chr186046472GT0.00409CYR61+FALSE
chr119543364TC0.00447LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1115249843GA0.00218NRAS-FALSE
chr1552203664AC0.01000TMOD3+FALSE
chr1179829096TC4.38746E-06TOR1AIP2-TRUEAluJrSINE,Alu
chr1201488771AG0.00062.FALSEAluSq2SINE,Alu
chr1431916927TC1.57126E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr132661594CT0.00528TXLNA+FALSE(T)nSINE,Alu
chr1201438098TG2.75480E-05PHLDA3-FALSE
chr10101992298TC0.00409CWF19L1-TRUEAluSq2SINE,Alu
chrX133930368TG0.00126FAM122B-FALSEG-richSINE,Alu
chr2118940466AT0.00169CXADR+FALSEAluYSINE,Alu
chr1145283718GA0.00989NBPF20,NOTCH2NL+FALSE
chr167874697TC0.00119SERBP1-TRUEAluSx3SINE,Alu
chr239050141AC0.00924DHX57-FALSE
chr340578941AG0.00293ZNF621+TRUEAluJrSINE,Alu
chr456291751AC0.00291TMEM165+FALSE
chr4155457051AT0.00378PLRG1-FALSEL2d2SINE,Alu
chr3197682718TC0.00163IQCG,RPL35A+,-FALSE
chr9119162301AT0.00778PAPPA,PAPPA-AS1+,-FALSE(GAAA)nSINE,Alu
chr346623292TC0.00408TDGF1+FALSEAluSx3SINE,Alu
chr16162583GA0.00281CHD5-FALSE
chr825272364CG0.00693DOCK5+FALSE
chr5179048449TG0.00394HNRNPH1-FALSE
chr42841893AG0.00974SH3BP2+TRUEAluJbSINE,Alu
chr5150827307GT0.00708SLC36A1+FALSE
chr7129592510GT0.00165UBE2H-FALSE
chr634231301GC0.00772.FALSE
chr636894337GA0.00607C6orf89+FALSEGA-richSINE,Alu
chr1657505637TA0.00643POLR2C+FALSE
chr358304244GA0.00560RPP14+FALSEAluSzSINE,Alu
chr1757279167AG6.96573E-05PRR11+TRUEAluSq2SINE,Alu
chr1117648269GA0.00988.FALSEAluSz6SINE,Alu
chr561683960AG0.00491.FALSE
chr285546474TC0.00051TGOLN2-TRUEAluScSINE,Alu
chr1013320236CT0.00011PHYH-FALSE
chr120975992TC2.78350E-06PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr147099235AC0.00919.FALSE
chr1145693061AG0.00158NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr5149829071TC0.00407RPS14-FALSE
chr1730327115CT0.00522SUZ12+FALSE
chr1146740502CG0.00692CHD1L+FALSE
chr4248840AG0.00655ZNF876P+TRUEAluYk3SINE,Alu
chr1225707043TC2.18813E-07ENAH-FALSE
chr12124146073AG0.00085GTF2H3+FALSEAluSx4SINE,Alu
chr4170678993TC3.15742E-05HPF1-FALSE
chr1253435627AG0.00133EIF4B+FALSE
chr39821914CT7.78954E-06TADA3-FALSE
chr1224380757AG0.00618DEGS1+FALSEAluSxSINE,Alu
chr2236677551TC7.06365E-05MYH9-FALSE
chr238971637GA2.13337E-05SRSF7-FALSE
chr132373563GA0.00089PTP4A2-FALSE
chr484525974TC0.00255GPAT3+FALSE(TTGTT)nSINE,Alu
chr1475202512AG0.00053FCF1+TRUEAluScSINE,Alu
chr3196670087GA4.07177E-06NCBP2-AS2+FALSE
chr192976590GA0.00629EVI5-FALSE
chr6150047376TC0.00102NUP43-TRUEAluScSINE,Alu
chr632148031AG1.10299E-06.FALSE
chr671299074AG0.00824.FALSEAluSx1SINE,Alu
chr136522615AG0.00658.FALSEAluScSINE,Alu
chr2110842200CA0.00131MALL-FALSE
chr136024788CT2.88658E-15NCDN+FALSE
chr1178444613TG0.00630RASAL2+FALSE
chr144443175AC0.00026ATP6V0B+FALSE
chr1463841402AC0.00692PPP2R5E-FALSE
chr167874697TC4.44446E-05SERBP1-TRUEAluSx3SINE,Alu
chr986553587GA0.00556C9orf64-FALSE
chr159148136TC0.00244MYSM1-FALSE
chr141972198AT0.00276HIVEP3-FALSE
chr1118552273CT0.00243.FALSE
chr5178986987CT0.00651RUFY1+FALSE
chr1227071525CT0.00085PSEN2+FALSE
chr310192784AG1.73909E-05VHL+TRUEAluSx1SINE,Alu
chr1778921108GA0.00065RPTOR+FALSE
chr11118471800TA0.00875ARCN1+FALSEAluSx3SINE,Alu
chr2143638992TA0.00089KYNU+FALSE
chr352084040CT4.81509E-06DUSP7-FALSE
chr11345051AG0.00362.FALSEAluSgSINE,Alu
chr1145369706TC0.00186NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chrX77083617TC3.46806E-05MAGT1-TRUEAluSz6SINE,Alu
chr1013320126TA0.00830PHYH-FALSE
chr2217366919AG0.00480.FALSEAluSz6SINE,Alu
chr631321806CT6.66134E-15.FALSE
chr12125269475TC0.00184SCARB1-FALSE
chr5139876355GA0.00815ANKHD1,ANKHD1-EIF4EBP3+FALSEGA-richSINE,Alu
chr12123640853CG0.00667.FALSE
chr165299558CT0.00161JAK1-FALSE
chr1465400786TG0.00077CHURC1-FNTB,CHURC1+FALSEAluSxSINE,Alu
chr34403260CT0.00603SUMF1-FALSE
chr593018884AC0.00538FAM172A-FALSE(TCA)nSINE,Alu
chr822995145TC3.53807E-06TNFRSF10D-FALSE
chr16683561CG0.00732PHF13+FALSE
chr3195393406CT0.00690SDHAP2+FALSE
chr3178978532TC0.00061KCNMB3-FALSE
chr5115165731TC5.24208E-07ATG12-TRUEAluSq2SINE,Alu
chr6158613390TC0.00416GTF2H5+FALSE
chr1117645998AG0.00057.FALSE
chr9115446725TC0.00917INIP-TRUEAluJrSINE,Alu
chr141088377CT8.47840E-10RIMS3-FALSE
chr185742155GA0.00813BCL10,LOC646626+,-FALSE
chr848890247AG2.58682E-14MCM4+TRUEAluJbSINE,Alu
chr3160286646CT0.00086.FALSE
chr1089005496TG0.00138NUTM2A-AS1-FALSEMSTB1SINE,Alu
chr479832870AT0.00655BMP2K+FALSE
chr16314743CT6.72719E-05GPR153-FALSE
chr1149943157GA0.00060OTUD7B-FALSE
chr4177252326AG0.00098SPCS3+TRUE
chr5149829076GC0.00288RPS14-FALSE
chr5175816759TA0.00018.FALSE
chr10124913908CA0.00784BUB3+FALSE
chr2178406767AT0.00416AGPS+FALSE
chr133149399AG0.00148SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1212911836TC0.00675NSL1-FALSE
chr1145695329AG0.00400NBPF20,NBPF10+FALSEAluSzSINE,Alu
chr9115447535TC3.15593E-07INIP-TRUEAluJbSINE,Alu
chr237330620TC0.00216.FALSEAluSq2SINE,Alu
chr399463810GT0.00599MIR548G,COL8A1+,-FALSE
chr2232028396AG0.00701PSMD1+FALSE
chr1161932324AG0.00104ATF6+FALSE
chr642855972AG3.93003E-05RPL7L1+TRUEAluSzSINE,Alu
chr110519936TC0.00029.FALSEAluJrSINE,Alu
chr193617546TC0.00026TMED5-FALSE
chr163009329TG0.00155DOCK7-FALSE
chr340503729AG5.91625E-05RPL14+FALSE
chr1205577901GA0.00904ELK4-FALSE
chr127861184GT0.00425AHDC1-FALSE(TCTTTT)nSINE,Alu
chr145975345AG0.00227MMACHC+TRUEAluSg7SINE,Alu
chr1957802824GA0.00924ZNF460+FALSE
chrX123046290AG0.00524XIAP+TRUEAluJbSINE,Alu
chr291806132TA0.00460.FALSEMLT1H1SINE,Alu
chr1148003734TC0.00015NBPF8-TRUEL1MC4SINE,Alu
chr1120164994CT0.00829ZNF697-FALSE
chr191990445AG0.00784CDC7+FALSELFSINE_VertSINE,Alu
chr1939433142TA0.00215FBXO17-FALSEAluJbSINE,Alu
chr1951172526GC0.00276SHANK1-FALSE
chr425749192CT0.00642SEL1L3-FALSE
chr315112630CT0.00017RBSN-FALSEAluSq2SINE,Alu

Differential Expression Gene Analysis