Dataset Overview
RBPHLTF
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR958NDU
PlatformHiSeq
Pubmed ID32252787

HLTF - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of HLTF
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of HLTF


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr3100467676AT0.00288TFG+FALSE
chr2102508654TG0.00010MAP4K4+FALSE
chr127248275CT0.00047NUDC+FALSE
chr1675479467TC0.00160TMEM170A-TRUEAluJbSINE,Alu
chr133086812TC0.00250.FALSEAluYSINE,Alu
chr1610625406TC1.26372E-11EMP2-TRUEAluSxSINE,Alu
chr19416568CT0.00061SPSB1+FALSE
chr711148863TA0.00455PHF14+FALSE
chr1144909956GA0.00310NBPF20,PDE4DIP+,-FALSE
chr366419942AG0.00284SLC25A26+FALSE
chr135816903CT0.00174ZMYM4+FALSE
chr1719091395CT0.00852.FALSEU3SINE,Alu
chrX77084042TC0.00703MAGT1-TRUEAluSzSINE,Alu
chr744842429TG0.00384PPIA+FALSE
chr115909850CG0.00660AGMAT-FALSE
chr178286136TA0.00706RPL26-FALSE
chr1148558269AG0.00538NBPF15+FALSEAluJbSINE,Alu
chr4154257510AC0.00121TRIM2+FALSE(A)nSINE,Alu
chr16282400TC0.00118ICMT-TRUEAluSzSINE,Alu
chr133149495AG0.00652SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr129519665TC0.00680MECR-TRUEAluJbSINE,Alu
chr344790879TC0.00453KIAA1143-TRUEAluYSINE,Alu
chr2178406762GT0.00708AGPS+FALSE
chr1144828683CG3.91144E-05NBPF20,NBPF9+FALSE
chr178414310CA0.00131FUBP1-FALSE
chr1110040310AG2.45230E-05CYB561D1+FALSE
chr110516656CT0.00808.FALSE
chr579922263TG0.00913DHFR-FALSEHAL1SINE,Alu
chr185785107TC4.02203E-05DDAH1-FALSE
chr1946289409CT6.23760E-05DMWD-FALSE
chr1160966434TC0.00175F11R-TRUEAluSgSINE,Alu
chr155316322AG0.00266DHCR24-FALSE
chr3156259295TC0.00039SSR3-TRUEAluSq2SINE,Alu
chr1160658566AC0.00387PRPF19-FALSE
chr1765335454TC9.75664E-07PSMD12-TRUEAluSxSINE,Alu
chr11417649TG0.00274ATAD3B+FALSE
chr2157440644GC0.00394GPD2+FALSE
chr16282318TC0.00418ICMT-TRUEAluSzSINE,Alu
chr145976723TC0.00239MMACHC,PRDX1+,-FALSE
chr110517290TC0.00366.FALSEAluJrSINE,Alu
chr116891340TA0.00404NBPF1-FALSE
chr1101444791CT0.00268SLC30A7+FALSE
chr489181451TC8.32748E-05PPM1K-TRUEAluSx1SINE,Alu
chr1179832748GC7.50400E-12TOR1AIP2-FALSEFLAM_CSINE,Alu
chr317201871TC0.00626TBC1D5-FALSE
chr128825419AG0.00204PHACTR4+TRUEAluSgSINE,Alu
chr1256510702TC0.00052RPL41+FALSE
chr116893721AC0.00043NBPF1-FALSE
chr1118502750TC0.00922WDR3,SPAG17+,-FALSE(GT)nSINE,Alu
chr2101622700AG0.00387RPL31+FALSE
chr2217366901AG0.00143.FALSEAluSz6SINE,Alu
chr1765335253TC0.00344PSMD12-TRUEAluSxSINE,Alu
chr145976723TC5.68535E-05MMACHC,PRDX1+,-FALSE
chr3179042866AG0.00806ZNF639+FALSEAluSpSINE,Alu
chr118708789AG0.00237RPL27A+TRUEAluSpSINE,Alu
chr146830110AG0.00283NSUN4+TRUEAluSx1SINE,Alu
chr246612340GT0.00094EPAS1+FALSE
chr1941097276CG0.00188SHKBP1+FALSE
chr237327589TC0.00253.FALSE
chr1212911836TC0.00675NSL1-FALSE
chr72473753CT0.00806CHST12+FALSE(CCGC)nSINE,Alu
chr1158067061GT0.00093KIRREL+FALSE
chr1466209686TA7.37485E-06FUT8+FALSE(TT)nSINE,Alu
chr1206566195CT7.54522E-05SRGAP2+FALSE
chr2191745655CG0.00163GLS+FALSE
chr2164466039AC0.00456FIGN-FALSE
chrX16781687AG0.00298.FALSEAluSx1SINE,Alu
chr3148748339GT0.00666HLTF-FALSE
chr199672312TC4.30163E-05.FALSEAluJrSINE,Alu
chr12121118CT0.00234FAAP20-FALSE
chr126608014CA1.07737E-06.FALSE
chr765618249AG0.00785CRCP+TRUEAluSpSINE,Alu
chr1145291217CT0.00415NBPF20+FALSE
chr138158211CT0.00091CDCA8+FALSE
chr2191556844TC0.00024NAB1+FALSE
chr3195963395AG0.00028.FALSE
chr3169988286CT0.00029PRKCI+FALSE
chr170718273AT0.00256.FALSE
chr579923788TC0.00693DHFR-TRUEAluSpSINE,Alu
chr122854931CA7.08508E-09ZBTB40+FALSEA-richSINE,Alu
chr112082926AG0.00229MIIP+FALSE
chr110517306TC0.00022.FALSEAluJrSINE,Alu
chr1205056844TA0.00225RBBP5-FALSE
chr132373831TG0.00252PTP4A2-FALSE(T)nSINE,Alu
chr572801323CA0.00119BTF3+FALSE
chr124134721TC0.00113HMGCL-FALSE
chr132681795CT0.00791DCDC2B,TMEM234+,-FALSE
chr1773939212TC0.00376ACOX1-TRUEAluSx1SINE,Alu
chr116061035GC0.00089PLEKHM2+FALSE
chr247703548GA5.05442E-05MSH2+FALSE
chr2197001673TC0.00043STK17B-FALSE
chr1226923938AC0.00160ITPKB-FALSE
chr1541593268AG0.00084.FALSEAluSz6SINE,Alu
chr123636273AT0.00442HNRNPR-FALSE
chr19163334TC0.00889.FALSEAluSpSINE,Alu
chr1145323656AT0.00593NBPF20,NBPF10+FALSE
chr3160154971TC0.00820TRIM59-FALSEAluJbSINE,Alu
chr136602176GT0.00017TRAPPC3-FALSE
chr1158057633CG0.00031KIRREL+FALSE
chr119542455TC0.00048LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr2025428750AG3.17139E-06GINS1+TRUEAluJbSINE,Alu
chr117393889AG0.00390PADI2-FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr7100804140CT0.00377AP1S1+FALSE
chr127874481CA0.00046AHDC1-FALSE
chr2113334178AT0.00654POLR1B+FALSEL1MA10SINE,Alu
chr1015120279TC0.00255ACBD7-TRUEL1PA7SINE,Alu
chr766105163CG0.00594KCTD7+FALSE
chr1146033815GA0.00307NBPF20,NBPF10,NBPF25P,NBPF11+,-FALSE
chr439552066TC0.00370UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr286272758GA0.00023POLR1A-FALSE
chr275882576TC0.00328MRPL19+FALSE
chr286252198TC0.00076POLR1A-TRUEAluSq2SINE,Alu
chr116901668TC0.00421NBPF1-FALSE
chr116891340TA0.00724NBPF1-FALSE
chr122352040GT0.00255LOC101928043,LINC00339+,-FALSE
chr1179042701AG0.00132FAM20B+TRUEAluSx1SINE,Alu
chr310192642AG0.00714VHL+TRUEAluSx1SINE,Alu
chr5118174855TC1.06010E-07DTWD2-TRUEAluYSINE,Alu
chr1254634306TC0.00616CBX5-TRUEAluJrSINE,Alu
chr136388197CT0.00315AGO1+FALSE
chr18413317AC0.00957RERE-FALSE
chr72394991CT9.93448E-08EIF3B+FALSE
chr1540955103AG0.00372.FALSEAluJbSINE,Alu
chr996439041AT0.00751PHF2+FALSE
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr3122283290GC0.00029DTX3L,PARP9+,-FALSE
chr12125512541AG6.52088E-06.FALSE
chr11431295TC0.00400ATAD3B+FALSE
chr452888026AC0.00677SGCB-FALSE
chr136067677TC5.01583E-07PSMB2-TRUEAluSzSINE,Alu
chr1167782827GA0.00163ALDH3B1+FALSE
chr3196660344TA0.00366SENP5+FALSE
chr2204055626GT0.00130NBEAL1+FALSE
chr2220422583GA0.00089OBSL1-FALSE
chr799636947AG0.00851ZKSCAN1+FALSEAluSx1SINE,Alu
chr1153609268GA0.00263CHTOP+FALSE
chr3184300061TC0.00518EPHB3+FALSE(TG)nSINE,Alu
chr116958063CT0.00246.FALSE
chr535878249GA0.00421IL7R+FALSE
chr2203741032TC0.00282.FALSEAluJrSINE,Alu
chr3141667149TC0.00273TFDP2-TRUEAluSxSINE,Alu
chr5125961447AG0.00242PHAX+TRUEAluSz6SINE,Alu
chr137958451CG0.00882MEAF6-FALSEMER5BSINE,Alu
chr1610625075TC2.22045E-15EMP2-TRUEAluSx3SINE,Alu
chr145279813TC0.00614.FALSE(TCTT)nSINE,Alu
chr298089475TA0.00385LOC100506076,LOC100506123-FALSE
chr1204189357CT0.00835PLEKHA6-FALSE
chr1251325237AG5.73531E-05METTL7A+TRUEAluSq2SINE,Alu
chr6114182271GA0.00011MARCKS+FALSE
chr1244219905GT0.00772ZBTB18+FALSE
chr1144595935GA0.00636NBPF20+FALSEAluJbSINE,Alu
chr310192826AG0.00037VHL+TRUEAluSx1SINE,Alu
chr3196662641TC0.00059NCBP2-FALSE
chr3192515510GT0.00559MB21D2-FALSE
chr210586899GA0.00312ODC1,SNORA80B-FALSE
chr110519912TC5.10285E-06.FALSEAluJrSINE,Alu
chr1774561213AG0.00241SNHG16+FALSE
chr146033514GA0.00073AKR1A1+FALSEAluYk3SINE,Alu
chr631506635TG6.78064E-05.FALSE
chr2105881486AG0.00042TGFBRAP1-FALSE
chr3129152089GA0.00154MBD4-FALSE
chr1222906392CT0.00804BROX+FALSEAluSxSINE,Alu
chr3186838874GA0.00972RPL39L-FALSE
chr147184569GC0.00061EFCAB14-FALSE
chr1757279167AG0.00071PRR11+TRUEAluSq2SINE,Alu
chr1117530217CT0.00048PTGFRN+FALSE
chr2174086940CA0.00047ZAK,MLK7-AS1+,-FALSEAluJoSINE,Alu
chr1917412218CT0.00790ABHD8-FALSE
chr2121979980GA0.00525TFCP2L1-FALSEL1MB8SINE,Alu
chr237331207TC0.00745.FALSEAluSx1SINE,Alu
chr5178986987CT0.00651RUFY1+FALSE
chr175288084TA0.00232RABEP1+FALSE
chr2178406763TC0.00452AGPS+FALSE
chr152375564TC0.00866RAB3B-FALSE
chr1914203874AC0.00870PRKACA-FALSE(A)nSINE,Alu
chr717384358AG7.93091E-07AHR+TRUEAluSxSINE,Alu
chr11252749TC0.00875CPSF3L-TRUEAluSpSINE,Alu
chr1110136458AG0.00136GNAI3+FALSE
chr823294732CT0.00415ENTPD4-FALSE
chr110519910TC0.00735.FALSEAluJrSINE,Alu
chr146774813CG0.00766UQCRH+FALSE
chr5179041779CT0.00430HNRNPH1-FALSE
chr1145512937AG1.47906E-06NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr13545198TC0.00013TPRG1L+FALSE
chr12125513906CA0.00464.FALSEAluSx1SINE,Alu
chr7100279138AT0.00741GIGYF1-FALSEA-richSINE,Alu
chr1145290818CG0.00287NBPF20+FALSE
chr128607959CA0.00215SESN2+FALSE
chr136068369TC0.00404PSMB2-TRUEAluScSINE,Alu
chr568426312GA0.00344SLC30A5+FALSE
chr174928967TG0.00921KIF1C+FALSEAluYSINE,Alu
chr110519888TC0.00666.FALSEAluJrSINE,Alu
chr1184761162TC0.00685FAM129A-TRUEAluJoSINE,Alu
chr110517567TC0.00578.FALSEAluSx1SINE,Alu
chr7156764972GA0.00871NOM1+FALSE
chr5179665201CT0.00037MAPK9-FALSEAluSx4SINE,Alu
chr1146650091CA0.00361PDIA3P1+FALSE
chr2238244963AG0.00124COL6A3-FALSE
chr142644770CT1.21495E-06FOXJ3-FALSE
chr299813002AG0.00067MRPL30+TRUEAluJbSINE,Alu
chr167874270GA0.00019SERBP1-FALSE
chr126755494AG0.00874LIN28A+TRUEAluScSINE,Alu
chr21168781CA0.00650SNTG2+FALSE
chrM2619AT0.00012RNR2+FALSELSU-rRNA_HsaSINE,Alu
chr110521238TC0.00597DFFA-TRUEAluYSINE,Alu
chr13395039GA0.00027ARHGEF16+FALSE
chr2200813126TC0.00713TYW5-FALSE
chr197543764CT0.00353DPYD-FALSE
chr132374019GA0.00297PTP4A2-FALSE
chr3160219829CT0.00654KPNA4-FALSE(TA)nSINE,Alu
chr42943361TC7.19955E-07NOP14-AS1,NOP14+,-FALSE
chr1461112736TG0.00418SIX1-FALSE(T)nSINE,Alu
chr1788840TC0.00415LINC01128+FALSE
chr2216148871TG0.00071.FALSETigger1SINE,Alu
chr186119441GA0.00905ZNHIT6-FALSE
chr1160967754TC0.00563F11R-TRUE(T)nSINE,Alu
chr186049389TA0.00420CYR61+FALSE
chr199672318TC2.91158E-05.FALSEAluJrSINE,Alu
chr1231557255CG0.00056EGLN1-FALSE(GCC)nSINE,Alu
chrX23721424GC0.00651.FALSE
chr274332840GC4.77205E-06TET3+FALSE
chr144447004GA0.00768B4GALT2+FALSE(CAG)nSINE,Alu
chr1204524914AG0.00766MDM4+TRUEAluSxSINE,Alu
chr127992624GA0.00813IFI6-FALSE
chr1765334767TC3.33546E-08PSMD12-TRUEAluSqSINE,Alu
chr112677525GA0.00122DHRS3-FALSE(A)nSINE,Alu
chr2203742188TC0.00522.FALSEAluJbSINE,Alu
chr116918486CT0.00415NBPF1-FALSE
chr1955597GT3.81431E-06AGRN+FALSE
chr1156675377GC0.00935CRABP2-FALSE
chr187213188CA0.00236SH3GLB1+FALSE
chr697592897AC0.00144MMS22L-FALSE
chr1761502459TA0.00161TANC2+FALSE
chr11251841TC0.00915CPSF3L-TRUEAluSq2SINE,Alu
chr128566461TC1.61071E-05.FALSEAluSx1SINE,Alu
chr2113289701TG0.00994TTL+FALSE
chr1158067059AC0.00655KIRREL+FALSE
chr128607959CA0.00230SESN2+FALSE
chr246612338TG0.00018EPAS1+FALSE
chr2204162277AG0.00097CYP20A1+TRUEAluSxSINE,Alu
chr116893763TC0.00996NBPF1-FALSE
chr1209602381GA0.00075MIR205HG+FALSEAluJbSINE,Alu
chr1738632679TG0.00044TNS4-FALSE(GT)nSINE,Alu
chr1230415244TC0.00780GALNT2+FALSE
chr6108364582TC0.00577OSTM1-FALSE
chr1145689611CA0.00142NBPF20,NBPF10+FALSEAluSgSINE,Alu
chr495588274GA0.00095PDLIM5+FALSE
chr9132266644AG0.00081LINC00963+TRUEAluSxSINE,Alu
chr1100491475AG0.00508SLC35A3+FALSE
chr1959095456AG0.00125CENPBD1P1+TRUEAluJbSINE,Alu
chr2129024188TG0.00051HS6ST1-FALSE
chr1214524496TC0.00879PTPN14-TRUEAluSgSINE,Alu
chr136529549AG0.00806.FALSEAluJrSINE,Alu
chr568738649AT0.00716.FALSE
chr163790503TC0.00289FOXD3+FALSE
chr3172351006CG6.14326E-06NCEH1-FALSE
chr3194349178CT0.00881TMEM44-FALSE
chr165899366AC0.00593LEPR,LEPROT+FALSE
chr3155658362CT0.00807.FALSEMIR3SINE,Alu
chr15937327CT0.00703NPHP4-FALSE
chr1464951277TC0.00077ZBTB25-TRUEAluSpSINE,Alu
chr1563363384CA0.00161TPM1+FALSE
chr110596341CT0.00552PEX14+FALSE
chr20279774AC0.00056ZCCHC3+FALSEL2bSINE,Alu
chr197116159GT0.00368INSR-FALSE
chr1235492546TG0.00786GGPS1+FALSE
chr117299387TA0.00941CROCC+FALSE
chr72274209TC0.00578MRM2-FALSEAluJrSINE,Alu
chr228002599TA0.00566MRPL33+FALSE
chr131344952CT0.00544SDC3-FALSE
chr2035521047TA0.00064TLDC2,SAMHD1+,-FALSE
chr16585131CT0.00141NOL9-FALSE
chr5149361415AG0.00290SLC26A2+TRUE
chr5130729522TG0.00506CDC42SE2+FALSE(T)nSINE,Alu
chr11595586TC0.00108CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr1114306369AT0.00834RSBN1-FALSE
chr340578815AG0.00041ZNF621+FALSEAluJrSINE,Alu
chr110521130TC0.00860DFFA-TRUEAluYSINE,Alu
chr1942753034AG0.00883ERF-FALSE
chr1225974592TG2.09928E-05SRP9+FALSEAluJrSINE,Alu
chr19328092AG0.00058H6PD+TRUEAluJrSINE,Alu
chr8144827207AT0.00038FAM83H-AS1+FALSEERVL-B4-intSINE,Alu
chr642981525GC0.00041MEA1-FALSE
chr1341635234TC0.00395.FALSE
chr11419700AG0.00464ATAD3B+TRUEAluYk2SINE,Alu
chr366024384GC0.00096MAGI1-FALSE
chr133149496AG0.00662SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr19160963TC0.00354.FALSEAluJbSINE,Alu
chr77918285GA0.00255UMAD1+FALSE
chr720177613TC0.00913MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr132661594CT0.00528TXLNA+FALSE(T)nSINE,Alu
chr1162407518TC3.11115E-06GANAB-TRUEAluYSINE,Alu
chr456295166AG0.00988CLOCK-FALSE
chr125894468CG0.00265LDLRAP1+FALSEMIRbSINE,Alu
chr1160966299TC1.46976E-05F11R-TRUEAluSgSINE,Alu
chr285773595TC0.00774GGCX-TRUEAluSx1SINE,Alu
chr1475202288CT0.00706FCF1+FALSEAluScSINE,Alu
chr1145689717AG3.41980E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr1742880190TC0.00284GJC1-TRUEAluJbSINE,Alu
chr1246829616TC0.00029CNST+FALSE
chr921331119CT0.00343KLHL9-FALSEL1MSINE,Alu
chr2218572597AG0.00322PEX26+TRUEAluYf1SINE,Alu
chr1145512024AG0.00041NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1155214017CA0.00946GBA-FALSEAluSx3SINE,Alu
chr2101622888TA7.56266E-05RPL31+FALSE
chr128826223AG0.00990PHACTR4+TRUEAluJbSINE,Alu
chrX123046779AG0.00629XIAP+TRUEAluSzSINE,Alu
chr6158505088AG0.00083SYNJ2+FALSE
chr299812864AG0.00810MRPL30+TRUEAluJbSINE,Alu
chr261370704TA0.00747LOC339803-FALSE
chr7129963777TG0.00874CPA4+FALSE(TG)nSINE,Alu
chr2164466037AT0.00090FIGN-FALSE
chr1206578650GC0.00159SRGAP2+FALSE
chr345960556CT0.00500FYCO1-FALSE
chr191457883CG2.74690E-05APC2+FALSE
chr112072783CA0.00914MFN2+FALSE
chr119543457TC4.71011E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1296259951GA0.00328SNRPF+FALSE
chr3141879040TC0.00101GK5-TRUEFLAM_CSINE,Alu
chr220818517TC0.00748HS1BP3-FALSE
chr146159809TA0.00761TMEM69+FALSE
chr1229738170TG0.00168TAF5L-FALSE
chr720177519TC0.00885MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr348787633TC0.00287PRKAR2A-TRUEAluSpSINE,Alu
chr1145376020GA0.00478NBPF20,NBPF10+FALSE
chr8144332082TC7.73207E-05ZFP41+FALSE
chr2121749583TC0.00120GLI2+FALSE
chr1181058313GA0.00651IER5+FALSE
chr133149376AG0.00424SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1148252785TC0.00314NBPF8,NBPF14,NBPF9-FALSE
chr5130538043AG0.00713LYRM7+TRUEAluSpSINE,Alu
chr2133032035TA1.90109E-05SOD1+FALSE

Differential Expression Gene Analysis