Dataset Overview
RBP
PABPC4
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR455VZH
Platform
HiSeq
Pubmed ID
32252787
PABPC4 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of PABPC4
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
29.02
29.62
0.32638
3.40689E-05
8.37202E-05
AAAS
21.26
17.73
-0.40508
3.07500E-06
8.63273E-06
AACS
17.52
13.8
-0.45701
1.77874E-09
7.16677E-09
AADAC
0.87
1.38
0.69124
0.00793
0.01356
AAGAB
4.83
6.38
0.40696
0.00023
0.00051
AAK1
1.2
3.65
1.66438
1.68588E-32
3.47947E-31
AAMDC
27.35
19.96
-0.53087
1.61118E-05
4.13150E-05
AAMP
124.44
101.34
-0.36722
2.16559E-07
6.98162E-07
AAR2
22.2
17.87
-0.41573
1.65785E-07
5.41780E-07
AARS
51.81
69.86
0.30116
7.69264E-06
2.05559E-05
Showing 1 to 10 of 8,976 entries
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Function Analysis of Target Genes of PABPC4
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52622648_52622741_52619601_52619745_52645340_52645387
0.00114
0.036
DataSet_01_398
View details
ABCC2
101556540_101556610_101554169_101554225_101556853_101557853
0.00237
-0.087
DataSet_01_398
View details
ABCC2
101556531_101556610_101554169_101554225_101556853_101557853
0.00980
-0.052
DataSet_01_398
View details
AC093642.5
243058333_243058383_243056789_243056892_243061115_243061208
0.00019
-0.505
DataSet_01_398
View details
ACAA1
38167652_38167832_38167316_38167372_38168000_38168191
0.00103
-0.064
DataSet_01_398
View details
ACAA1
38167652_38167843_38167316_38167372_38168000_38168191
0.00121
-0.092
DataSet_01_398
View details
ACSL3
223791734_223791960_223789173_223789313_223793579_223793654
0.00500
-0.04
DataSet_01_398
View details
ACSL3
223791734_223791907_223789173_223789313_223793579_223793654
0.00569
-0.013
DataSet_01_398
View details
ACSM2B
20586743_20586829_20575990_20576175_20587528_20587606
0.00675
-0.04
DataSet_01_398
View details
ADD3
111892062_111892158_111890120_111890244_111893083_111893969
0.00886
0.18
DataSet_01_398
View details
Showing 1 to 10 of 396 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52623792_52623840_52642232_52642465_52619601_52619745
0.00116
-0.263
DataSet_01_398
View details
AC005152.2
70070689_70072874_70078061_70078182_70067183_70067372
0.00176
0.15
DataSet_01_398
View details
ACAA1
38169276_38169357_38170780_38170879_38167652_38168191
0.00011
0.083
DataSet_01_398
View details
ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00003
-0.086
DataSet_01_398
View details
AFMID
76200908_76200981_76201173_76201271_76198783_76198832
0.00000
-0.378
DataSet_01_398
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AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00000
-0.259
DataSet_01_398
View details
AHSG
186336324_186336426_186337645_186337729_186334231_186334316
0.00044
-0.006
DataSet_01_398
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AHSG
186334975_186335139_186336324_186336426_186334231_186334316
0.00424
-0.166
DataSet_01_398
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AHSG
186336079_186336284_186336300_186336426_186334975_186335139
0.00844
-0.01
DataSet_01_398
View details
ALB
74272345_74272478_74274310_74274522_74270832_74270890
0.00000
0.168
DataSet_01_398
View details
Showing 1 to 10 of 115 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38167652_38168191_38168000_38168191_38167316_38167372
0.00122
-0.094
DataSet_01_398
View details
ACSS2
33508751_33508969_33508751_33508942_33509132_33509276
0.00035
0.037
DataSet_01_398
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ACSS2
33508334_33508563_33508334_33508512_33508808_33508969
0.00174
0.076
DataSet_01_398
View details
AHSG
186337615_186337863_186337615_186337729_186338374_186339107
0.00008
0.007
DataSet_01_398
View details
AL163636.6
21152745_21152917_21152745_21152855_21161705_21161809
0.00767
-0.011
DataSet_01_398
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ALB
74279136_74279307_74279136_74279299_74280751_74280884
0.00000
-0.023
DataSet_01_398
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ATXN2L
28844759_28844966_28844759_28844829_28845385_28845532
0.00813
0.042
DataSet_01_398
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BPTF
65941524_65942441_65941524_65942012_65943841_65943924
0.00001
0.277
DataSet_01_398
View details
CETN2
151999110_151999321_151999251_151999321_151998145_151998304
0.00343
0.5
DataSet_01_398
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CFB
31914333_31914443_31914333_31914383_31914783_31914969
0.00260
-0.007
DataSet_01_398
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Showing 1 to 10 of 41 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC002985.3
19021779_19022025_19021779_19021880_19023792_19023855
0.00082
0.065
DataSet_01_398
View details
ACAD11
132297639_132297900_132297639_132297725_132298335_132298402
0.00249
-0.195
DataSet_01_398
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ACADVL
7127798_7127871_7127802_7127871_7127639_7127712
0.00309
0.032
DataSet_01_398
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AP1G2
24031170_24031316_24031170_24031275_24031496_24031624
0.00157
0.11
DataSet_01_398
View details
AP1G2
24031170_24031275_24031170_24031262_24031496_24031624
0.00823
0.05
DataSet_01_398
View details
AP1G2
24031170_24031316_24031170_24031262_24031496_24031624
0.00963
0.056
DataSet_01_398
View details
AP1G2
24031170_24031300_24031170_24031275_24031496_24031624
0.00628
0.106
DataSet_01_398
View details
AP2S1
47342721_47342877_47342721_47342835_47349249_47349399
0.00401
0.036
DataSet_01_398
View details
APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00031
-0.032
DataSet_01_398
View details
APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00134
-0.011
DataSet_01_398
View details
Showing 1 to 10 of 82 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00922
0.058
DataSet_01_398
View details
ACAD11
132297639_132298402_132297639_132297725_132298335_132298402
0.00279
-0.183
DataSet_01_398
View details
ACADVL
7127639_7127871_7127639_7127712_7127802_7127871
0.00183
0.059
DataSet_01_398
View details
AP1G2
24031170_24031624_24031170_24031262_24031496_24031624
0.00127
0.052
DataSet_01_398
View details
AP1G2
24031170_24031624_24031170_24031275_24031496_24031624
0.00564
0.151
DataSet_01_398
View details
AP3D1
2109084_2109957_2109084_2109206_2109871_2109957
0.00404
0.073
DataSet_01_398
View details
ASCC2
30189348_30189665_30189348_30189479_30189565_30189665
0.00302
0.249
DataSet_01_398
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ATG16L1
234198499_234198999_234198499_234198620_234198893_234198999
0.00339
-0.19
DataSet_01_398
View details
ATP13A1
19767468_19767725_19767468_19767575_19767655_19767725
0.00828
-0.134
DataSet_01_398
View details
ATP6V0B
44442697_44443967_44442697_44442888_44443652_44443967
0.00033
0.089
DataSet_01_398
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
16112795
A
G
4.56234E-06
FBLIM1
+
FALSE
chr1
115259341
A
C
2.70927E-07
NRAS
-
FALSE
chr1
53359181
A
G
0.00699
ZYG11A
+
TRUE
AluSx
SINE,Alu
chr1
158631171
A
C
0.00815
SPTA1
-
FALSE
chr1
182568729
C
G
0.00012
RGS16
-
FALSE
chr1
27202963
C
T
0.00106
.
FALSE
AluSq2
SINE,Alu
chr1
1421186
C
T
0.00834
ATAD3B
+
FALSE
chr1
179852074
T
C
0.00338
TOR1AIP1
+
FALSE
chr1
1666834
G
A
0.00037
SLC35E2
-
FALSE
L1MEg
SINE,Alu
chr1
31732603
A
C
0.00148
SNRNP40
-
FALSE
Showing 1 to 10 of 208 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression