Dataset Overview
RBPKHSRP
Knock-MethodshRNA
RBP FamilyKH_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR561CBC
PlatformHiSeq
Pubmed ID32252787

KHSRP - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of KHSRP
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of KHSRP


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr5150578574AG0.00447CCDC69-FALSE
chr6111591610AG0.00105.FALSEFLAM_ASINE,Alu
chr363996262CT0.00681PSMD6-AS2,PSMD6+,-FALSE
chr826435509TC0.00121DPYSL2+FALSE(TC)nSINE,Alu
chr755433880GC0.00115LANCL2+FALSE
chr340503557TC0.00746RPL14+FALSE
chr357542173CT0.00020PDE12+FALSE
chr1911560461AG0.00034PRKCSH+TRUEAluSxSINE,Alu
chr1560678712GA0.00801ANXA2-FALSE
chr6160113872AG0.00863SOD2-FALSE
chr136068184TC0.00177PSMB2-TRUEAluScSINE,Alu
chr12133389998TC0.00829GOLGA3-FALSE
chr537290400TC0.00085.FALSEAluSzSINE,Alu
chr1161141432CG0.00508B4GALT3-FALSE
chr1022824829TC0.00207PIP4K2A-FALSE
chr12120898553AG0.00233GATC+TRUEAluYSINE,Alu
chr195658344GA0.00100TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr19162929CG0.00584.FALSE
chr1146495577TA0.00072LOC728989-FALSE
chr848890288AG0.00210MCM4+TRUEAluJbSINE,Alu
chrX77083673TC0.00090MAGT1-TRUEAluSz6SINE,Alu
chr1552203664AC0.01000TMOD3+FALSE
chr116929327CT0.00315NBPF1-FALSEERVL-E-intSINE,Alu
chr369154343CG0.00408ARL6IP5+FALSE
chr232534897AG0.00111.FALSEAluSx1SINE,Alu
chr8143763618CG0.00421PSCA+FALSE
chr7120740103GT0.00601CPED1+FALSE
chr3188597556AG0.00309LPP+FALSE
chr766105198CA0.00456KCTD7+FALSE
chr110517659TC0.00679.FALSEAluSx1SINE,Alu
chr9125866691AC0.00177RABGAP1+FALSE
chr315114395TC0.00333RBSN-TRUEAluYSINE,Alu
chr2204162277AG0.00097CYP20A1+TRUEAluSxSINE,Alu
chr552388458AT0.00152ITGA2+FALSE
chr2216908679CT0.00988PECR-FALSE
chr115736752GA0.00170EFHD2+FALSE
chr11469546GA0.00766ATAD3A+FALSE
chr19163290TC0.00016.FALSEAluSpSINE,Alu
chr116889866GA0.00051NBPF1-FALSE
chr3183476685GA0.00032YEATS2+FALSE
chr76066461TC2.08606E-05EIF2AK1-FALSE
chr1233514975GT0.00584MLK4+FALSE
chr1146627405CG0.00074PRKAB2-FALSE
chr115668319GA0.00489FHAD1+FALSE
chr43242100GA0.00916HTT+FALSE
chr1475202402AG0.00141FCF1+TRUEAluScSINE,Alu
chr1205739266CT0.00069RAB29-FALSE
chr133148210AG0.00114SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1168220489AG0.00126.FALSEAluSz6SINE,Alu
chr111783889AG0.00746.FALSEAluSqSINE,Alu
chr357549504AG0.00384PDE12+TRUEAluJbSINE,Alu
chr1182569318GT0.00101RGS16-FALSE
chr344790781TC0.00887KIAA1143-TRUEAluYSINE,Alu
chr131732599TG0.00827SNRNP40-FALSE
chr1436784095CT0.00866MBIP-FALSE
chr1150281017AG0.00057MRPS21+TRUEAluSzSINE,Alu
chr76501830GA0.00217KDELR2-FALSE
chr16283264TC0.00095ICMT-TRUEAluSx3SINE,Alu
chr133149375AG0.00840SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr153711735GC0.00884LRP8-FALSE
chr117345246AT0.00812SDHB-FALSE
chr286249961TC0.00368LOC90784-TRUEAluJrSINE,Alu
chr1204525669AG0.00169MDM4+TRUEAluSzSINE,Alu
chr2178186556GA0.00917LOC100130691-FALSE
chr3101369192CT0.00761ZBTB11-FALSE
chr136322433GA0.00663AGO4+FALSE
chr146077218AG0.00543NASP+TRUEAluSc8SINE,Alu
chr152816674TC1.79626E-07CC2D1B-TRUEAluSx1SINE,Alu
chr473922978TC0.00079COX18-TRUEAluSzSINE,Alu
chr989627066AG0.00588LOC440173-FALSE
chr6150047376TC0.00306NUP43-TRUEAluScSINE,Alu
chr299812450AG7.07141E-05MRPL30+TRUEAluSxSINE,Alu
chr3119212009GA0.00241POGLUT1+FALSE
chr174929000AG0.00214KIF1C+TRUEAluYSINE,Alu
chr919373161AG0.00647DENND4C+TRUEMADE1SINE,Alu
chr2187544230TA0.00930ITGAV+FALSE
chr1150208462AC9.89925E-05ANP32E-FALSE
chr6149912555GA0.00551.FALSE
chr1145441843GA0.00744NBPF20,NBPF10,TXNIP+FALSE
chr1104097685CT0.00721RNPC3,AMY2B+FALSE
chr2114352179GA1.68965E-05WASH2P+FALSE
chr2134728113AG0.00531IFNAR1+TRUEAluScSINE,Alu
chr13546132GA0.00113TPRG1L+FALSEAluSzSINE,Alu
chr642854681AG0.00011RPL7L1+TRUEAluScSINE,Alu
chr153291425AG0.00517ZYG11B+TRUEAluJrSINE,Alu
chr1145513114AG0.00033NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1012292344AG0.00434CDC123+FALSE
chr532586387TC0.00569SUB1+FALSE
chr1474526154TC0.00030BBOF1,ALDH6A1+,-FALSEAluSpSINE,Alu
chr190470915TA9.94810E-07ZNF326+FALSE
chr1921366997AG0.00727ZNF431+TRUEAluScSINE,Alu
chr147142539TA0.00066EFCAB14-AS1,EFCAB14+,-FALSE
chr175196073CT0.00159CRYZ-FALSE
chr1160990876CA1.09997E-06F11R-FALSE
chr16582527TC0.00139NOL9-TRUEAluSx1SINE,Alu
chr1148251009TC0.00065NBPF8,NBPF14,NBPF9-TRUE
chr193827764AG0.00098DR1+FALSE
chr23504687AG0.00755ADI1-FALSE
chr1156499969TC8.53229E-06IQGAP3-FALSE
chr1552202957GT0.00094TMOD3+FALSE(T)nSINE,Alu
chr190493918GA0.00166ZNF326+FALSE
chr344487862GA0.00262ZNF445-FALSE
chr270452146TG0.00192TIA1-FALSE
chr3121435624CT0.00063GOLGB1-FALSE
chrX118672561TC2.49155E-08CXorf56-TRUEAluSxSINE,Alu
chr110521254TC2.63330E-05DFFA-TRUEAluYSINE,Alu
chr140923019GA0.00019ZFP69B+FALSE
chr120826788AT6.12716E-05MUL1-FALSE
chr724731065CT0.00414MPP6+FALSE(TGTATG)nSINE,Alu
chr5139931630AT0.00052SRA1-FALSE
chr1118068699CG0.00191.FALSE
chr13545192CG0.00011TPRG1L+FALSE
chr1541590288GT0.00349OIP5-AS1+FALSE
chr1585190470GT8.70862E-05WDR73-FALSE
chr133148196AG0.00303SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr119542310TC0.00510LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1149582019AG0.00082LINC00623,LINC00869,LOC103091866+FALSE
chr2197004439AG0.00034STK17B-FALSE
chr143272841AT0.00029SVBP-FALSE
chr3112320485TC0.00107LINC01279-TRUEAluJbSINE,Alu
chr179003523CG0.00036PTGFR+FALSE
chr1120163247TC0.00010ZNF697-FALSE
chr1144868170CT0.00750NBPF20,PDE4DIP+,-FALSE
chr276672504AG0.00010.FALSE7SKSINE,Alu
chr2128620373CT0.00553AMMECR1L-FALSE
chr1116235277CT0.00396VANGL1+FALSE
chr1421928940TC0.00212RAB2B-TRUEAluSpSINE,Alu
chr1145116141GA0.00266NBPF20,SEC22B+FALSE
chr128261662AG0.01000SMPDL3B+FALSE
chr167874270GA0.00019SERBP1-FALSE
chr146076599AG0.00116NASP+TRUEAluSxSINE,Alu
chr1144851537AG0.00275NBPF20,PDE4DIP+,-FALSE
chr285548075CA0.00932TGOLN2-FALSE
chr140214261AG0.00879PPIE+TRUEAluSq2SINE,Alu
chr136068196TC0.00376PSMB2-TRUEAluScSINE,Alu
chr1539887848GA0.00664THBS1+FALSE
chr116112795AG0.00145FBLIM1+FALSE
chr145975498AG0.00018MMACHC+TRUEAluSx4SINE,Alu
chr154691921GA0.00010SSBP3-FALSE
chr116160968CT0.00524FLJ37453-FALSE(T)nSINE,Alu
chr119543799TC0.00076LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr224223251AG0.00489UBXN2A+TRUEAluScSINE,Alu
chrX54587218AG0.00014GNL3L+TRUEAluSq2SINE,Alu
chr126608019TA3.63623E-05.FALSE
chr349397323TC0.00000RHOA-TRUE
chr9114696428GT0.00163UGCG+FALSE(TGTTTTT)nSINE,Alu
chr1145281408CT0.00220NBPF20,NOTCH2NL+FALSE
chr116912099GC0.00450NBPF1-FALSE
chr1256510704GA0.00042RPL41+FALSE
chr2035409839TC0.00556SOGA1-TRUEAluSxSINE,Alu
chr165692499CT0.00235AK4+FALSE(T)nSINE,Alu
chr642855972AG3.93003E-05RPL7L1+TRUEAluSzSINE,Alu
chr439551179TC0.00142UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1590820083AG4.07036E-06.FALSEAluYSINE,Alu
chr128836912AG3.63020E-05SNHG3,RCC1+TRUEAluScSINE,Alu
chr657034840TG0.00581ZNF451,LOC101927211+,-FALSE
chr766421684TG0.00042TMEM248+FALSEAluJrSINE,Alu
chr310192672GA5.82875E-07VHL+FALSEAluSx1SINE,Alu
chr9133579734AG0.00129EXOSC2+TRUEAluSx3SINE,Alu
chr11252443TC0.00392CPSF3L-TRUEAluJrSINE,Alu
chr2198368110CA0.00053HSPE1,HSPE1-MOB4+FALSE
chr275120159CT0.00180HK2+FALSE
chr11662694TC0.00398SLC35E2-TRUEAluYSINE,Alu
chr1684778690CT0.00799USP10+FALSE
chr1919791650AG1.64958E-05ZNF101+TRUEAluScSINE,Alu
chr237331065TC0.00585.FALSEAluSx1SINE,Alu
chr1135017260TC0.00224PDHX+FALSE
chr1205577901GA0.00904ELK4-FALSE
chr1590820171AG0.00185.FALSE
chr1109465168TA0.00246GPSM2+FALSE
chr1211920314TC0.00938LPGAT1-FALSE
chr116890421GA0.00024NBPF1-FALSE
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr13100638107AT0.00841ZIC2+FALSE
chr417802956TC0.00480DCAF16-TRUEAluSzSINE,Alu
chr110042937AG2.41028E-05NMNAT1+TRUEAluScSINE,Alu
chr16283439TC0.00786ICMT-TRUEAluSx3SINE,Alu
chr132953296AG5.26589E-05ZBTB8B+TRUEAluSzSINE,Alu
chr154354935GC0.00831YIPF1-FALSE
chr410076658TC6.66134E-16WDR1-FALSE
chr116929327CT5.08143E-05NBPF1-FALSEERVL-E-intSINE,Alu
chr3101579158AG0.00022NFKBIZ+FALSEAluJoSINE,Alu
chr631657413TC0.00066.FALSE
chr110518756TC0.00937.FALSEAluSx1SINE,Alu
chr452888499GA8.91315E-05SGCB-FALSE
chr291805928TC0.00000.FALSEMLT1H1SINE,Alu
chr152306079TA0.00606NRDC-FALSE(TCA)nSINE,Alu
chr3141164940CA0.00194ZBTB38+FALSE
chr197144750TC0.00262.FALSE
chr320025662TG0.00028RAB5A,PP2D1+,-FALSE
chr112401868AC0.00394VPS13D+FALSE
chr1186646405CA9.05139E-05PRSS23+FALSEL2bSINE,Alu
chr136067833TC3.75622E-05PSMB2-TRUEAluSzSINE,Alu
chr5145666109AT0.00728RBM27+FALSE
chr330733403AT0.00840TGFBR2+FALSE(TA)nSINE,Alu
chr175288078AG0.00081RABEP1+FALSE
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr1728963296AG0.00572LOC107133515+TRUEAluJr4SINE,Alu
chr1919791270AG0.00732ZNF101+TRUEAluSq2SINE,Alu
chr1116235186AG0.00054VANGL1+FALSE
chr299813003AG2.46688E-05MRPL30+TRUEAluJbSINE,Alu
chr194351065AT0.00142GCLM-FALSE
chr112071680AG5.54475E-07MFN2+FALSE
chr652267967AC0.00424PAQR8+FALSE
chr1200375404TG0.00030ZNF281-FALSE
chr136031860GT0.00564NCDN+FALSE
chr126799971TA0.00713HMGN2+FALSE
chr340578997AG0.00094ZNF621+TRUEAluJrSINE,Alu
chr110520649TC0.00629DFFA-TRUEAluSc8SINE,Alu
chr5130494984AT0.00018HINT1-FALSE
chr56633042CT0.00377NSUN2-FALSE
chr177759578AG0.00955AK5+FALSE
chr1156044222GT0.00037MEX3A-FALSE(T)nSINE,Alu
chr72290637CT0.00956NUDT1+FALSE
chr273460299GC0.00180PRADC1-FALSE(CGGCGC)nSINE,Alu
chr1145323656AT3.43611E-06NBPF20,NBPF10+FALSE
chr11594835CG0.00195CDK11B,SLC35E2B-FALSE
chr138279666CT0.00521MTF1-FALSE(T)nSINE,Alu
chr145975348TC0.00062MMACHC+FALSEAluSg7SINE,Alu
chr1179829093TC0.00056TOR1AIP2-TRUEAluJrSINE,Alu
chr11593857TC0.00217CDK11B,SLC35E2B-FALSE
chr3172115474AG0.00012FNDC3B+FALSE(A)nSINE,Alu
chr138275432GT0.00057MTF1-FALSE
chr116841561GA0.00025.FALSE
chr237518045GC0.00342PRKD3-FALSE
chr1761502459TA0.00161TANC2+FALSE
chr42940371TC0.00150NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr4153898334AG0.00662FHDC1+FALSEAluJoSINE,Alu
chr764023437AG0.00073ZNF680-FALSE
chr193308168TA0.00314FAM69A-FALSE
chr220449068AG0.00014PUM2-FALSE
chr2206986978TC0.00159.FALSEAluJrSINE,Alu
chr145975498AG0.00064MMACHC+TRUEAluSx4SINE,Alu
chr1153917621GC0.00020DENND4B-FALSE
chr2128602455TC0.00632.FALSEAluSq2SINE,Alu
chr11118940957CG0.00642VPS11+FALSE
chr2207174868GA1.60070E-05ZDBF2+FALSE
chr3195963400TG0.00155.FALSE
chr299812464AG1.88485E-05MRPL30+TRUEAluSxSINE,Alu
chr116841972GA1.76809E-05.FALSEMER41ESINE,Alu
chr110043358AG0.00982NMNAT1+TRUEAluSx3SINE,Alu
chr112677549TA1.84464E-05DHRS3-FALSE(A)nSINE,Alu
chr2127826533AG0.00942BIN1-FALSE
chr333909024AT0.00134PDCD6IP+FALSE
chr1145499276CT0.00581NBPF20,NBPF10,LIX1L+FALSE
chr1168220427AG0.00670.FALSEAluSz6SINE,Alu
chr189518173TA0.00465GBP1-FALSE
chr2025428617AG0.00622GINS1+FALSEAluJbSINE,Alu
chr116893691CA0.00371NBPF1-FALSE
chr136531942AG0.00042.FALSEAluSq2SINE,Alu
chr2272203CT1.58440E-08ACP1+FALSE
chr237328013TC0.00401.FALSE
chr19328255AG0.00729H6PD+TRUEAluJrSINE,Alu
chr5125962169AG0.00013PHAX+TRUEAluScSINE,Alu
chr110520174TC0.00163.FALSEAluSxSINE,Alu
chr1957816261AG0.00156.FALSEAluYSINE,Alu
chr4108834529GT1.01126E-06SGMS2,LOC101929595+,-FALSE
chr2043707842AG0.00100STK4+TRUEAluJbSINE,Alu
chr114150116CT7.82303E-05PRDM2+FALSE
chr7128143606AG4.95106E-06.FALSEAluJr4SINE,Alu
chr1153782688GT0.00032GATAD2B-FALSE
chr2128620436CT0.00342AMMECR1L-FALSE
chr1101443701AG0.00749SLC30A7+FALSE
chr1028971535TA0.00169BAMBI+FALSE
chr1145509569AG0.00777NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr5180669695TC0.00101RACK1-TRUEAluSx1SINE,Alu
chr132799435AT0.00515MARCKSL1-FALSE
chr1113240711GA0.00454MOV10+FALSE
chr136067677TC5.01583E-07PSMB2-TRUEAluSzSINE,Alu
chr264327544GT0.00340PELI1-FALSE
chr725161424TC0.00669CYCS-TRUEAluSz6SINE,Alu
chr1667715404TC0.00102GFOD2-TRUEAluSzSINE,Alu

Differential Expression Gene Analysis