Dataset Overview
RBPEIF4G1
Knock-MethodshRNA
RBP FamilyMIF4G
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR509LIV
PlatformHiSeq
Pubmed ID32252787

EIF4G1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EIF4G1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EIF4G1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr136534736AG0.00016.FALSEAluJoSINE,Alu
chr1176733946AG0.00725ACER3+FALSEA-richSINE,Alu
chr1474526976TC0.00469BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr1145512073AG0.00285NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr101086810TA0.00245IDI2-AS1,IDI1+,-FALSE
chr2203430456TG0.00162BMPR2+FALSE
chr5177019207TG0.00584TMED9+FALSE
chr2204301754CG0.00012RAPH1-FALSE
chr146521559AT0.00177PIK3R3-FALSE
chr110518831TC0.00213.FALSEAluSx1SINE,Alu
chr116927419GA0.00493NBPF1-FALSE
chr76501820AT0.00531KDELR2-FALSE
chr1063852210CT0.00324ARID5B+FALSE
chr136068237TC0.00291PSMB2-TRUEAluScSINE,Alu
chr2208620129AG0.00061CCNYL1+TRUEEutTc1-N1SINE,Alu
chr192977228TC0.00206EVI5-TRUEAluJrSINE,Alu
chr1118472382GT0.00029WDR3+FALSE
chr1145284883AG0.00062NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr117313654CT0.00886ATP13A2-FALSE
chr12520435GC0.00041FAM213B+FALSE
chr126774224AG0.00295DHDDS+TRUEAluSz6SINE,Alu
chrX3526613CT0.00930PRKX-FALSE
chr345722381AG0.00996LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr1145513098AG0.00171NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr139470979CA0.00160AKIRIN1+FALSEAluSx1SINE,Alu
chr2130900880CT0.00044CCDC74B-FALSE
chr1144833382CT0.00325NBPF20+FALSEL1MEcSINE,Alu
chr1755761035GA0.00125MSI2+FALSE
chr126608009TA0.00496SH3BGRL3+FALSE
chr1919793168AG0.00481ZNF101+TRUEAluSzSINE,Alu
chr16282371TC0.00054ICMT-TRUEAluSzSINE,Alu
chr3150345451AG2.37481E-05SELT+TRUE
chr5177019196GC0.00509TMED9+FALSE(GCG)nSINE,Alu
chr1207247477TC0.00078PFKFB2+FALSEMER5BSINE,Alu
chr244459528GA0.00126PPM1B+FALSE
chr210942687CT0.00082PDIA6-FALSE
chr16583138TC0.00010NOL9-TRUEAluSx4SINE,Alu
chr29629306GT0.00255ADAM17-FALSE
chr18045340CA0.00217PARK7+FALSE
chr534906156TC2.52494E-05RAD1-TRUEAluSx1SINE,Alu
chr136794250AG0.00324.FALSEAluJbSINE,Alu
chr6138734422CT0.00447HEBP2+FALSE
chr339452945TA0.00462RPSA+FALSEMER5BSINE,Alu
chr1153609268GA0.00263CHTOP+FALSE
chr585916592GA0.00018.FALSE
chr28823956AG2.51922E-06ID2+FALSE
chr1108113839TC1.78857E-05VAV3-FALSE
chr1680636805TG0.00766CDYL2-FALSE
chr1145500925TA0.00997NBPF20,NBPF10,LIX1L+FALSE
chr315483019GT0.00751EAF1+FALSE
chr570503890AT0.00188.FALSE
chr147843356AT0.00556CMPK1+FALSE
chr116912029CG0.00699NBPF1-FALSE
chrX77083673TC0.00090MAGT1-TRUEAluSz6SINE,Alu
chr1193474585TG0.00531TAF1D-FALSE
chr19294903CG0.00353H6PD+FALSE
chr192941357AG0.00296GFI1-FALSE
chr1142805281CT0.00242.FALSE
chr128661656AG0.00026MED18+TRUEAluSgSINE,Alu
chr116529004AC3.00007E-07ARHGEF19-FALSE
chr1145369709AG0.00258NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr110043363AG0.00429NMNAT1+TRUEAluSx3SINE,Alu
chr116841972GA1.76809E-05.FALSEMER41ESINE,Alu
chr838829839AG0.00184PLEKHA2+TRUEAluJr4SINE,Alu
chr1144917546AG0.00614NBPF20,PDE4DIP+,-FALSE
chr3196670090GA0.00059NCBP2-AS2+FALSE
chr8141530799GA0.00525.FALSE
chr131905886CA0.00335SERINC2+FALSE
chr1071909957GT0.00853.FALSE
chr116893686GC0.00171NBPF1-FALSE
chr1757281058AG0.00061PRR11+TRUEAluSzSINE,Alu
chr1160966353TC0.00011F11R-TRUEAluSgSINE,Alu
chr314986098TC3.23580E-05FGD5-AS1-TRUEFLAM_CSINE,Alu
chr274686329CT0.00640INO80B-WBP1,WBP1+FALSE
chr119586458AG1.61978E-09MRTO4+TRUEAluSzSINE,Alu
chr3122283290GC0.00029DTX3L,PARP9+,-FALSE
chr2242176182GA2.43141E-09HDLBP-FALSE
chr2018468404TC0.00301RBBP9-TRUEAluSz6SINE,Alu
chr119542463TC0.00182LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr352289709GC4.88711E-11WDR82-FALSEMIRSINE,Alu
chr2114220055TC9.23000E-05CBWD2+FALSE
chr647501448TC0.00017CD2AP+FALSE
chr237330620TC0.00216.FALSEAluSq2SINE,Alu
chr537291446TC6.87884E-05.FALSEAluSx3SINE,Alu
chr16653508GA0.00320KLHL21-FALSE
chr1765334886TC8.05380E-09PSMD12-TRUEAluSqSINE,Alu
chr471682341TC0.00584GRSF1-TRUEAluSz6SINE,Alu
chr136067749TC0.00748PSMB2-TRUEAluSzSINE,Alu
chr136068237TC0.00054PSMB2-TRUEAluScSINE,Alu
chr140537924GA0.00404CAP1+FALSE(A)nSINE,Alu
chr110521237TC0.00200DFFA-TRUEAluYSINE,Alu
chr525415881TC0.00911.FALSE
chr5125962354AG3.71532E-05PHAX+TRUEAluScSINE,Alu
chr1120164252GA0.00139ZNF697-FALSE
chr123689522GT0.00570ZNF436-FALSE
chr6134492485CT0.00245SGK1-FALSE
chr1469704553GT7.62587E-05EXD2+FALSE
chr191457883CG2.74690E-05APC2+FALSE
chr28823941GA0.00053ID2+FALSE
chr1144599819CT0.00682NBPF20+FALSE
chr3179117242TC0.00011GNB4-TRUEAluSzSINE,Alu
chr119585554AG0.00117MRTO4+TRUEAluSc8SINE,Alu
chr3148748339GT0.00666HLTF-FALSE
chr194335330AT0.00366DNTTIP2-FALSE
chr1674655596TG0.00028RFWD3-FALSEAluSxSINE,Alu
chr121611798CT0.00338LINC00942+FALSE
chr2201676441GA0.00140LOC101927795,BZW1+,-FALSE
chr261764920CA0.00662XPO1-FALSE
chr110438006AT6.81521E-05KIF1B+FALSEAluSgSINE,Alu
chr1376378459TC0.00239LMO7+FALSE
chr1610623553TC0.00024EMP2-TRUEAluSpSINE,Alu
chr744800040CA0.00565ZMIZ2+FALSE
chr119238556GA6.03260E-07IFFO2-FALSE
chr119542401TC0.00071LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1946053393TC0.00514OPA3-TRUEAluSx1SINE,Alu
chr1847014856TA0.00722RPL17-C18orf32,RPL17-FALSE
chr579277950CA0.00037MTX3-FALSE(AC)nSINE,Alu
chr1211836207TA0.00432NEK2-FALSE
chrX3526615GT0.00820PRKX-FALSE
chr232235359AC0.00664MEMO1-FALSE
chr1206637133CT0.00909SRGAP2+FALSE
chr1179044242AG0.00335FAM20B+TRUEAluSxSINE,Alu
chr1121133392TC0.00651SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr5149363214AG0.00040SLC26A2+TRUEAluJrSINE,Alu
chr1933470874AG0.00119RHPN2-FALSE
chr158999651TG0.00332OMA1-FALSE
chr110520331CT0.00060.FALSEAluSx1SINE,Alu
chr11252248AG0.00503CPSF3L-FALSEAluSxSINE,Alu
chr1062554474TG6.65730E-05CDK1+FALSE
chr145975358AG0.00089MMACHC+TRUEAluSg7SINE,Alu
chr16282315TC0.00508ICMT-TRUEAluSzSINE,Alu
chr1149581866CG0.00774LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chr128261662AG0.01000SMPDL3B+FALSE
chrX16781186AG0.00220.FALSEAluJoSINE,Alu
chr193308168TA0.00314FAM69A-FALSE
chr345748599TA0.00470SACM1L+FALSE
chr1668962CT0.00852.FALSE
chr123240263GA5.22984E-05EPHB2+FALSE
chr145975670AG0.00530MMACHC+TRUEAluSx4SINE,Alu
chr1229631734TC0.00611NUP133-FALSE
chr16283264TC0.00479ICMT-TRUEAluSx3SINE,Alu
chr11344893AG7.94078E-08.FALSEAluSgSINE,Alu
chr126755291AG0.00044LIN28A+TRUEAluSx1SINE,Alu
chr11647871TC0.00906CDK11B,CDK11A-FALSE
chr1205272926CT0.00690NUAK2-FALSE
chr138423182GC0.00664SF3A3-FALSEAluJoSINE,Alu
chr358306802GA4.03384E-05.FALSEAluSzSINE,Alu
chr261277835AG0.00105PEX13+TRUEAluYSINE,Alu
chr483351845GT0.00422ENOPH1+FALSE
chr5137891109CG0.00031HSPA9-FALSE
chr153291420AG0.00011ZYG11B+TRUEAluJrSINE,Alu
chr133149375AG0.00148SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr16257826TC0.00192RPL22-FALSE
chr120978324TG0.00153PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr417803009TC0.00062DCAF16-TRUEAluSzSINE,Alu
chr1919793729AG0.00124ZNF101+TRUEAluSc8SINE,Alu
chr417628548AG0.00991.FALSEAluSzSINE,Alu
chr153708530TC9.40494E-05LRP8-FALSE(TA)nSINE,Alu
chr2202031806AT0.00543CFLAR+FALSE
chr1144014068TC0.00029.FALSE
chr1101442570AT0.00377SLC30A7+FALSE
chr220648140AC6.93182E-06RHOB+FALSE
chr119585493AG3.52757E-05MRTO4+TRUEAluSc8SINE,Alu
chr644417159AG0.00959CDC5L+TRUEFLAM_CSINE,Alu
chr110517623TC0.00348.FALSEAluSx1SINE,Alu
chr3197682718TC0.00163IQCG,RPL35A+,-FALSE
chr117735300CA0.00128RCC2-FALSE
chr633385535AG0.00671.FALSE
chr2101622884CA0.00387RPL31+FALSE
chr310285030GA0.00384IRAK2+FALSE
chr996438974CG0.00303PHF2+FALSE(CTCCAC)nSINE,Alu
chr124128467CT0.00481HMGCL-FALSE
chr373116347TA0.00109PPP4R2+FALSE
chr12123253723AG0.00371DENR+TRUE(AT)nSINE,Alu
chr141972198AT0.00276HIVEP3-FALSE
chr286252198TC0.00076POLR1A-TRUEAluSq2SINE,Alu
chr142881767GC0.00437RIMKLA+FALSE
chr1205687213TA0.00950NUCKS1-FALSE
chr1120839682AG0.00764FAM72B+FALSE
chr1101443701AG0.00406SLC30A7+FALSE
chr2180810264AT1.24157E-05CWC22-FALSE
chr2206980072GA1.35396E-05.FALSEMLT1A1SINE,Alu
chr110517276TC0.00039.FALSEAluJrSINE,Alu
chr5170837890CA0.00030.FALSE
chr310193358AG1.11864E-10VHL+TRUEL1ME4aSINE,Alu
chr1924104018AG0.00543ZNF726+FALSEAluSg4SINE,Alu
chr11018144TC0.00019C1orf159-FALSE
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr144818529TC0.00310ERI3-FALSE
chr138327457TC0.00305INPP5B-TRUEAluSx3SINE,Alu
chr315483744AG0.00083EAF1+FALSE
chr119543457TC4.71011E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1269237019AG2.84819E-05MDM2+TRUE
chr1173862270GC0.00197.FALSEAluSz6SINE,Alu
chr11118880839AG0.00922CCDC84+TRUEAluJbSINE,Alu
chr1778091513GA0.00810GAA+FALSE
chr1757279281AG0.00918PRR11+TRUEAluSq2SINE,Alu
chr5122682348AG0.00377CEP120-FALSE
chr126755303AG0.00129LIN28A+TRUEAluSx1SINE,Alu
chrX37699364CG0.00695DYNLT3-FALSE
chr1236717926TC0.00029HEATR1-FALSE
chr5149823795AT0.00261RPS14-FALSE
chr537290435TC8.22232E-07.FALSEAluSzSINE,Alu
chr119543353TC0.00081LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr286364709GT0.00237PTCD3+FALSE
chr642047426AG0.00676TAF8+TRUEAluSz6SINE,Alu
chr3195411239AC5.03065E-05SDHAP2+FALSE
chr133149496AG0.00308SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1156567496CT0.00012GPATCH4-FALSEMIR3SINE,Alu
chr136068369TC5.31121E-05PSMB2-TRUEAluScSINE,Alu
chr1144606996GC0.00107NBPF20+FALSE
chr124934236AG0.00596NCMAP+TRUEAluSz6SINE,Alu
chr830643549GC0.00257PPP2CB-FALSE
chr2189159003GA0.00260GULP1+FALSE
chr11337734CT3.46713E-05MRPL20-FALSE
chr119543457TC0.00569LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr342594019CT3.51223E-05SEC22C-FALSE
chr2158169499AG0.00119GALNT5+FALSE
chr5141690819GA0.00062SPRY4-FALSE
chr119542631TC0.00198LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr3156258319TC0.00012SSR3-TRUEAluYk3SINE,Alu
chr631112484CT0.00538.FALSE
chr152306082AT0.00038NRDC-FALSE(TCA)nSINE,Alu
chr11593857TC0.00424CDK11B,SLC35E2B-FALSE
chr1143189486AG0.00122LOC102723769-FALSE
chr12125514120AG0.00232.FALSE(TA)nSINE,Alu
chr362282908CT0.00281PTPRG-AS1-FALSE
chr344791343TC0.00539KIAA1143-FALSEAluJrSINE,Alu
chr2143638994GA0.00075KYNU+FALSE
chr126143725AT0.00116SEPN1+FALSEAluSxSINE,Alu
chr3121351287AG0.00656HCLS1-FALSE
chr1117617705AG0.00081TTF2+FALSE
chr324163645CG1.00972E-05THRB-FALSE
chr1220231963TC0.00343RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr3138121198CT0.00076MRAS+FALSE
chr1143399181TG0.00832.FALSE
chr318427924GT0.00312SATB1-FALSE
chr116913612GA0.00581NBPF1-FALSE
chr410443060TG0.00167ZNF518B-FALSE
chrX150573750AT0.00887VMA21+FALSE

Differential Expression Gene Analysis