Dataset Overview
RBPSRSF7
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR017PRS
PlatformHiSeq
Pubmed ID32252787

SRSF7 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SRSF7
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SRSF7


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1453243394TC0.00957GNPNAT1-TRUEAluSx3SINE,Alu
chr9131872862CG0.00131CRAT-FALSE
chr1100657416CT0.00058DBT-FALSEAluJbSINE,Alu
chr1120101744CA0.00540NAV2+FALSE
chr132096265AG0.00208PEF1-FALSE
chr1075009651TC0.00558DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr131732677GA0.00030SNRNP40-FALSEA-richSINE,Alu
chr1179843781TC0.00888TOR1AIP2-TRUEAluJbSINE,Alu
chr124934236AG0.00596NCMAP+TRUEAluSz6SINE,Alu
chr1777807105CA4.63827E-05CBX4-FALSE
chr144088117GT0.00731PTPRF+FALSE(T)nSINE,Alu
chr2197000455TC0.00426STK17B-FALSEAluSzSINE,Alu
chr1204526713AG0.00078MDM4+TRUEAluSxSINE,Alu
chr2198416722AT0.00970HSPE1-MOB4,MOB4+FALSE
chr457326291AG0.00415PAICS+TRUEAluJrSINE,Alu
chr273460315CT0.00315PRADC1-FALSE(CGGCGC)nSINE,Alu
chr841400022AG0.00148LOC102723729,GINS4+,-FALSEAluYSINE,Alu
chr136068281TC0.00026PSMB2-TRUEAluScSINE,Alu
chr1629454288TC9.60363E-06SMG1P6,BOLA2-SMG1P6-FALSETigger4aSINE,Alu
chr1578841543TA0.00438PSMA4+FALSE
chr1144014068TC0.00118.FALSE
chr286249961TC0.00173LOC90784-TRUEAluJrSINE,Alu
chr1150621090GA0.00212GOLPH3L-FALSE
chr1047221465TC0.00201.FALSEAluJbSINE,Alu
chr2220416967CT0.00300OBSL1-FALSE
chr424578019GA0.00000DHX15-FALSE
chr1226352498TG0.00636ACBD3-FALSE
chr417803537TC0.00366DCAF16-TRUEAluYSINE,Alu
chr2128605225GA0.00401POLR2D-FALSE
chr135648840GT0.00049SFPQ-FALSEAluSx3SINE,Alu
chr194703005CG0.00180ARHGAP29-FALSE
chr1937236432TC0.00333ZNF850-TRUEAluSpSINE,Alu
chr133148214AG0.00295SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1269237509AG1.55617E-05MDM2+TRUE
chr2171608711TA0.00492LOC101926913-FALSE
chr10102121601AG0.00000SCD+TRUEMLT1LSINE,Alu
chr1688789702GA0.00125PIEZO1-FALSE
chr1162752670GA0.00594.FALSE
chr193467756CT0.00485NFIC+FALSE(TA)nSINE,Alu
chr484525986GT0.00081GPAT3+FALSE(TTGTT)nSINE,Alu
chr1142688506TC4.54862E-05.FALSE
chr1269237507AG0.00889MDM2+TRUE
chr145975345AG9.37661E-05MMACHC+TRUEAluSg7SINE,Alu
chr140537944CA2.58277E-05CAP1+FALSE
chr140219280TC8.82951E-05PPIE+FALSE
chr1179084080TG0.00926ABL2-FALSE
chr1206579936AG0.00424SRGAP2+FALSE
chr349051841CA0.00132WDR6+FALSE
chr1713710GC0.00448LOC100288069-FALSEFRAMSINE,Alu
chr133148365GC0.00062SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr165692498TC0.00356AK4+FALSE(T)nSINE,Alu
chr112082926AG0.00594MIIP+FALSE
chr1110566210TA0.00832AHCYL1+FALSE
chr2131104524GA0.00912IMP4+FALSEL1MA9SINE,Alu
chr1209605646AC0.00478MIR205HG+FALSE(AGC)nSINE,Alu
chr138326661TC0.00023INPP5B-TRUEAluJrSINE,Alu
chr1227953267TG0.00233KLHL42+FALSE
chr224494671TC0.00244ITSN2-FALSE(TATCCT)nSINE,Alu
chr1162497663GA0.00365UHMK1+FALSE
chr1210025751GA4.42687E-05DIEXF+FALSETigger4aSINE,Alu
chr140537940AC0.00015CAP1+FALSE(A)nSINE,Alu
chr613790822TC0.00885MCUR1-TRUEAluSx1SINE,Alu
chr126606589CG0.00420SH3BGRL3+FALSE
chr453364GA0.00714ZNF718,ZNF595+FALSE
chr186049390AG0.00918CYR61+FALSE
chr2101010082GC0.00965CHST10-FALSE
chr189447839CG3.35704E-05KYAT3,RBMXL1-FALSE
chr861655619CT0.00475CHD7+FALSE
chr1675479377TC0.00639TMEM170A-TRUEAluJbSINE,Alu
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr119542631TC0.00176LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr1474524774TC0.00906BBOF1,ALDH6A1+,-FALSEAluSc8SINE,Alu
chr185742155GA0.00813BCL10,LOC646626+,-FALSE
chr132953214AG0.00837ZBTB8B+TRUEAluSzSINE,Alu
chr1552202957GT0.00094TMOD3+FALSE(T)nSINE,Alu
chr1153521525GA0.00013LOC101928034,S100A3+,-FALSE
chr842884422AG0.00768HOOK3+TRUEAluScSINE,Alu
chr1145303971AG0.00060NBPF20,NBPF10+FALSE
chr12109039869TC0.00795CORO1C-FALSE
chr16283434TC0.00285ICMT-TRUEAluSx3SINE,Alu
chr4190873405CT0.00325FRG1+FALSE
chr112072783CA0.00914MFN2+FALSE
chr116889563CA0.00090NBPF1-FALSE
chr357612623TC3.38108E-06DENND6A,PDE12+,-FALSE
chr457327087AG0.00047PAICS+TRUEAluSx1SINE,Alu
chr1946053393TC0.00514OPA3-TRUEAluSx1SINE,Alu
chr119665566AC0.00028CAPZB-FALSE
chr1757279258AG0.00095PRR11+TRUEAluSq2SINE,Alu
chr136067886TC0.00925PSMB2-TRUEAluSzSINE,Alu
chr642981526CG0.00129MEA1-FALSE
chr1229795330TC0.00334URB2+FALSE
chr1688789699AC0.00936PIEZO1-FALSE
chr841401571TA0.00240LOC102723729,GINS4+,-FALSE
chr1118068558GA0.00876.FALSE
chr133086876TC0.00672ZBTB8OS-TRUEAluYSINE,Alu
chr722983890TC0.00097FAM126A-FALSE
chr220424655GA0.00193SDC1-FALSE
chr2128602507TC4.02376E-05.FALSEAluSq2SINE,Alu
chr358306686AG0.00970.FALSEAluSzSINE,Alu
chr417804847TC0.00512DCAF16-TRUEAluSxSINE,Alu
chr285776621TC0.00194GGCX-TRUEAluSz6SINE,Alu
chr7152343700TC0.00061XRCC2-TRUEAluSx3SINE,Alu
chr1917535871AC0.00948MVB12A+FALSE
chr1110136328TA0.00577GNAI3+FALSE
chr110517659TC0.00679.FALSEAluSx1SINE,Alu
chr1206566904TC0.00322SRGAP2+FALSE
chr1953155625TC0.00074ZNF83-TRUEAluSgSINE,Alu
chr189477559CT0.00044GBP3-FALSE
chr3124948047CG0.00285ZNF148-FALSE
chr1230461079GA9.74527E-05PGBD5-FALSE
chr564964623TC1.14652E-05SGTB-TRUEAluSx1SINE,Alu
chr315113783TC0.00127RBSN-FALSEAluSz6SINE,Alu
chr128939803CT1.27013E-09TAF12-FALSE
chr457327092AG0.00091PAICS+TRUEAluSx1SINE,Alu
chrX123046598AG0.00371XIAP+TRUEAluSzSINE,Alu
chr132661600CT0.00235TXLNA+FALSE(T)nSINE,Alu
chr133148623AG0.00078SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr744841237TA0.00599PPIA+FALSE
chr1150704418TC0.00420CTSS-TRUEAluJoSINE,Alu
chr110438014AC0.00046KIF1B+FALSE
chr830536450TC8.74573E-07GSR-TRUEAluSpSINE,Alu
chr2196600548GT0.00036SLC39A10+FALSE
chr126604691GC0.00043CEP85+FALSE
chr138174583AC0.00644CDCA8+FALSE
chr298388810GT6.24900E-05TMEM131-FALSE
chr1230979207CA0.00643C1orf198-FALSE
chr126143731AG0.00337SEPN1+FALSEAluSxSINE,Alu
chr269685864AC0.00610AAK1-FALSE(CA)nSINE,Alu
chr119586135CT0.00063MRTO4+FALSE
chr439551018TC0.00224UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr317199207TA0.00075TBC1D5-FALSEA-richSINE,Alu
chr9116022893CA0.00060SLC31A1+FALSE
chr1207942509AG0.00177CD46+TRUEAluSg4SINE,Alu
chr1474526952TC0.00019BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr642856156AG0.00190RPL7L1+TRUEAluSzSINE,Alu
chr211323276TC0.00219ROCK2-FALSE
chr135652608AG0.00026SFPQ-FALSE
chr16282237TC0.00372ICMT-TRUEAluSzSINE,Alu
chr116910172GA0.00085NBPF1-FALSE
chr128661657AG0.00011MED18+TRUEAluSgSINE,Alu
chr344485914TC0.00920ZNF445-FALSEMIRbSINE,Alu
chr174672474GA0.00441FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr210908893AG0.00087ATP6V1C2+FALSE
chr274442407AG0.00122MTHFD2+FALSE
chr830536015TC6.64592E-05GSR-TRUEAluJrSINE,Alu
chr1153920564AG0.00747CRTC2-FALSE
chr552250837CT0.00017.FALSE
chr2191829133GA0.00097GLS+FALSE
chr1743364293CG0.00144MAP3K14-FALSE
chr1475202856AG3.12821E-09FCF1+TRUEAluSxSINE,Alu
chr42940243TA0.00028NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr333185036GA0.00573CRTAP+FALSEL2aSINE,Alu
chr111982580GA2.06927E-05KIAA2013-FALSE
chr937503313AG0.00584POLR1E+TRUEAluJbSINE,Alu
chr155317685GA0.00121DHCR24-FALSEMIRbSINE,Alu
chr192862862AG0.00024.FALSEAluJrSINE,Alu
chr256150885GA0.00624EFEMP1-FALSE
chr146075709AG0.00431NASP+TRUEAluSx4SINE,Alu
chr417803673TC0.00206DCAF16-TRUEAluYSINE,Alu
chr110240685CT0.00422UBE4B+FALSE
chr696054540GT0.00358MANEA+FALSE
chr1666923393AG0.00228PDP2+TRUEAluSzSINE,Alu
chr2277314GA0.00867ACP1+FALSE
chr3196769982CG0.00131DLG1-FALSE
chr2161130868AC0.00297RBMS1-FALSE
chr6160100926TC0.00028SOD2-TRUEAluSzSINE,Alu
chr237328013TC1.05952E-05.FALSE
chr1586288387CT0.00809AKAP13+FALSE
chr3196079305TC0.00161.FALSEAluSxSINE,Alu
chr3138121198CT0.00076MRAS+FALSE
chrX123046779AG0.00629XIAP+TRUEAluSzSINE,Alu
chr68014786TC0.00086BLOC1S5-TXNDC5,BLOC1S5,EEF1E1-BLOC1S5-TRUEAluSzSINE,Alu
chr35258236GC3.37681E-06EDEM1+FALSE
chr1746024807CT0.00295PNPO+FALSE
chr16582701TC1.54245E-05NOL9-TRUEAluSgSINE,Alu
chr919373160AG0.00404DENND4C+FALSEMADE1SINE,Alu
chr1201488143AG0.00492.FALSEAluSzSINE,Alu
chr136068243TC0.00217PSMB2-TRUEAluScSINE,Alu
chr1563363384CA0.00161TPM1+FALSE
chr1541590972AG2.40282E-05OIP5-AS1+TRUEAluSx1SINE,Alu
chr2232319524TA0.00245NCL-FALSE
chr1590820104AG4.84304E-05.FALSEAluYSINE,Alu
chr3185009713GT0.00106MAP3K13+FALSE
chr126802401TG4.43852E-05HMGN2+FALSE
chr568858545CG0.00034GTF2H2C,GTF2H2C_2+FALSEAluSzSINE,Alu
chr127205359TC0.00301.FALSEAluScSINE,Alu
chr61395043TC0.00055FOXF2+FALSE
chr123636275GT0.00185HNRNPR-FALSE
chr1179042482AG0.00079FAM20B+TRUEAluSx1SINE,Alu
chr110521238TC0.00173DFFA-TRUEAluYSINE,Alu
chr1164084160CT0.00895ESRRA,TRMT112+,-FALSE
chr593018883AT0.00393FAM172A-FALSE(TCA)nSINE,Alu
chr119586532AG0.00166MRTO4+TRUEAluSzSINE,Alu
chr417802819TC0.00316DCAF16-TRUEAluSzSINE,Alu
chr1143189486AG0.00122LOC102723769-FALSE
chr536143392CT0.00151LMBRD2-FALSE
chr116889596TC0.00905NBPF1-TRUE
chr1114443475AG0.00538AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr120977856TC0.00232PINK1,PINK1-AS+,-FALSE
chr857872143CT0.00037IMPAD1-FALSE
chr211323079TA0.00586ROCK2-FALSE(TA)nSINE,Alu
chr1204521616AG4.81420E-06MDM4+TRUEAluSgSINE,Alu
chr8144940327GA0.00989EPPK1-FALSE
chr417802819TC0.00747DCAF16-TRUEAluSzSINE,Alu
chr1197070442GT0.00468ASPM-FALSE
chr110519947TC0.00184.FALSEAluJrSINE,Alu
chr345125417GA0.00024CDCP1-FALSEAluJbSINE,Alu
chr144818525TC0.00235ERI3-FALSE
chr155319888TG0.00000DHCR24-FALSE
chr440138676AG0.00157N4BP2+FALSE
chr7128142833AG6.82570E-05METTL2B+TRUEAluSx1SINE,Alu
chr146164493TC0.00977IPP-TRUEAluJbSINE,Alu
chr116787985AG0.00053.FALSEAluSzSINE,Alu
chr119543465TC0.00709LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1117945040GA0.00181MAN1A2+FALSE
chr11345006AG1.26297E-06.FALSEAluSgSINE,Alu
chr1100490000AG0.00066SLC35A3+TRUEAluSgSINE,Alu
chr1629454295TC0.00019SMG1P6,BOLA2-SMG1P6-TRUETigger4aSINE,Alu
chr116889866GA0.00051NBPF1-FALSE
chr225042625CG0.00766CENPO,ADCY3+,-FALSE
chr1179876988CG0.00045TOR1AIP1+FALSE
chr237327685TC0.00057.FALSE
chr1569803GA0.00695.FALSE
chr2191556847GT9.96724E-06NAB1+FALSE
chr1566933AG3.50078E-05.FALSE
chr12125511242AG0.00015THRIL-FALSEAluSx1SINE,Alu
chr1077807027TC0.00089C10orf11+FALSE
chr1475202288CT0.00706FCF1+FALSEAluScSINE,Alu
chr1179044181AG0.00083FAM20B+TRUEAluSxSINE,Alu
chr4103718454TA0.00446LOC102723704,UBE2D3+,-FALSE
chr1114940209GT5.13716E-05TRIM33-FALSE(T)nSINE,Alu
chr16747231TG0.00269FBXL16-FALSE
chr110240859GT0.00312UBE4B+FALSE
chr29629955GT0.00866ADAM17-FALSE
chr2101623533CT0.00784RPL31+FALSE
chr6132780768GA0.00668STX7-FALSE
chr110520072TC0.00529.FALSEAluSxSINE,Alu
chr72274209TC0.00578MRM2-FALSEAluJrSINE,Alu
chr110520331CT0.00043.FALSEAluSx1SINE,Alu
chr1256510696AT0.00767RPL41+FALSE
chr613788297TC0.00077MCUR1-TRUEAluSxSINE,Alu
chr124022909TA0.00177RPL11+FALSE
chr2201774185TC0.00932.FALSEAluSzSINE,Alu
chrX123046306AG0.00016XIAP+TRUEAluJbSINE,Alu
chr2101622881CA1.48865E-05RPL31+FALSE
chr35257981TA3.55991E-06EDEM1+FALSE(ATTTT)nSINE,Alu
chr125894472CG0.00063LDLRAP1+FALSEMIRbSINE,Alu
chr119198414GA0.00028ALDH4A1-FALSE
chr1474526976TC1.13179E-06BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr1154916602CA0.00475PBXIP1-FALSEMIRbSINE,Alu
chr1745761108GT0.00127.FALSE
chr2206862015GA0.00026INO80D-FALSE
chr315114288TC7.51597E-05RBSN-TRUEAluYSINE,Alu
chr1160967856TC0.00491F11R-TRUEAluSpSINE,Alu

Differential Expression Gene Analysis