Dataset Overview
RBPPUS1
Knock-MethodshRNA
RBP FamilyPseudoU_synth_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR618IQH
PlatformHiSeq
Pubmed ID32252787

PUS1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PUS1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PUS1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1205719141CT0.00021NUCKS1-FALSE
chr154637167TC0.00027.FALSE
chr1100343254GA0.00725AGL+FALSE
chr340578843AG0.00221ZNF621+TRUEAluJrSINE,Alu
chr791502407CG0.00183MTERF1-FALSE
chr2204301753TA0.00012RAPH1-FALSE
chr1197053373GA0.00124ASPM-FALSE
chr332524229GT0.00359CMTM6-FALSE
chr729960812TA1.34773E-06SCRN1-FALSE
chr156961756AG0.00265PLPP3-FALSE
chr1144931727GA0.00211NBPF20,PDE4DIP+,-FALSE
chr186852362CA0.00073ODF2L-FALSEAluSzSINE,Alu
chr1779004271TC0.00200BAIAP2-AS1-FALSEAluSq2SINE,Alu
chr2110842200CA0.00131MALL-FALSE
chr919376252AT0.00367.FALSE
chr211323078CT0.00539ROCK2-FALSE
chr2114352238GA1.72390E-05WASH2P+FALSE
chr145976259AC0.00015MMACHC+FALSE
chr171531596AG0.00016ZRANB2-AS1,ZRANB2+,-FALSE
chr7158536267TC0.00298ESYT2-FALSE
chr110521130TC0.00807DFFA-TRUEAluYSINE,Alu
chr7144060286AG0.00674ARHGEF5+FALSE
chr5122359500AC0.00358PPIC-FALSE(AC)nSINE,Alu
chr152253845TC0.00889OSBPL9+FALSE(AT)nSINE,Alu
chr11431502GA0.00127ATAD3B+FALSE
chr237330144TG0.00478.FALSE
chr1013320236CT0.00011PHYH-FALSE
chr19161142TC8.95302E-05.FALSEAluSxSINE,Alu
chr239050141AC0.00924DHX57-FALSE
chr128825337AG0.00191PHACTR4+TRUEAluSgSINE,Alu
chr167875026AT0.00557SERBP1-FALSE
chr3197682718TC0.00163IQCG,RPL35A+,-FALSE
chr2109401281TG0.00116RANBP2+FALSE
chr1152884247AG0.00642IVL+FALSE
chr1151374016AG0.00822PSMB4+FALSE
chr439550558TC0.00441UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1549454018CT0.00053GALK2+FALSEAluSx1SINE,Alu
chr21652354GA0.00114PXDN-FALSE
chr1114443606AG0.00014AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr131405707GT0.00431PUM1-FALSE
chr5154194457AC0.00466LARP1+FALSE
chr349714225TC0.00023APEH+FALSE
chr268402152TC0.00794PNO1+FALSE
chr4120216206CT0.00205USP53+FALSE
chr199672318TC2.91158E-05.FALSEAluJrSINE,Alu
chr3156258230TC0.00011SSR3-TRUEAluYk3SINE,Alu
chr1168220364AG6.18665E-05.FALSEAluSz6SINE,Alu
chr42940265TC4.71601E-06NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1120539691GT0.00350NOTCH2-FALSE
chr19416568CT0.00061SPSB1+FALSE
chr1145509569AG0.00405NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr129464349AC0.00042LOC642846+FALSE
chr1152884246GT0.00536IVL+FALSE
chr237334139TC0.00146EIF2AK2-TRUEAluSzSINE,Alu
chr186815303TC0.00571ODF2L-FALSE
chr1168523016TC0.00016CPT1A-TRUEAluYSINE,Alu
chr131905905GC0.00028SERINC2+FALSE
chr132385071TA0.00436PTP4A2-FALSE
chr16282426TC0.00043ICMT-TRUEAluSzSINE,Alu
chr1016554732TA0.00706PTER+FALSE
chr23504687AG0.00755ADI1-FALSE
chr3109049163AG0.00440DPPA4-FALSEAluSpSINE,Alu
chr12241376CT0.01000SKI+FALSE
chr6166824702CT0.00587RPS6KA2-FALSE(T)nSINE,Alu
chr1760522252GA0.00187METTL2A+FALSE
chr3183889337AT3.46641E-05DVL3+FALSE
chr1075009722TC0.00555DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr11654038GA0.00290CDK11B,CDK11A-FALSE
chr1148023067CT0.00772NBPF8-FALSE
chr5154194456GC0.00831LARP1+FALSE
chr146033106TC0.00547AKR1A1+FALSE
chr1757279273AG0.00513PRR11+TRUEAluSq2SINE,Alu
chr120945055CT0.00269CDA+FALSE
chr275118737CT0.00154HK2+FALSE
chr12125514124AG3.15634E-06.FALSE(TA)nSINE,Alu
chr5131715011AG0.00761SLC22A5+FALSE
chr629912348AG0.00429.FALSE
chr43514539GA6.66134E-16LRPAP1-FALSE
chr1880052CT0.00231NOC2L-FALSE
chr5156905300AC0.00870ADAM19-FALSEMER92BSINE,Alu
chr175171751TC0.00161CRYZ-FALSE
chr1120163831AG0.00706ZNF697-FALSE
chr132372358CT0.00303PTP4A2-FALSE(CA)nSINE,Alu
chr76064012TC0.00240EIF2AK1-FALSE
chr9100777799GA0.00675ANP32B+FALSE
chr1120611960CT0.00062NOTCH2-FALSE
chr16282371TC0.00054ICMT-TRUEAluSzSINE,Alu
chr1200522059AT0.00163KIF14-FALSEAluSgSINE,Alu
chr210586903AC0.00041ODC1,SNORA80B-FALSE
chr344791343TC0.00539KIAA1143-FALSEAluJrSINE,Alu
chr133961147TG0.00196ZSCAN20+FALSE
chr540826639AG0.00978LOC100506548-FALSELTR78SINE,Alu
chr2206988075GA0.00672NDUFS1-FALSE
chr1206566948GA0.00568SRGAP2+FALSE
chr140538317CA0.00178CAP1+FALSE
chr3101546847GA0.00665NXPE3,NFKBIZ+FALSE
chr629910583CT4.95604E-05.FALSE
chr2174090332AC0.00918ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr555235866TA0.00073IL6ST-FALSE
chr1186946912GA0.00414PLA2G4A+FALSE
chr199673113TC0.00330.FALSEAluSx3SINE,Alu
chr132697110AT5.19592E-06EIF3I+FALSEAluSpSINE,Alu
chr3196466874GT0.00226PAK2+FALSE
chr110521254TC0.00522DFFA-TRUEAluYSINE,Alu
chr310028294GA1.35555E-07EMC3-FALSE
chr1469254646TC0.00181ZFP36L1-FALSE
chr138001685TC0.00050SNIP1-TRUEAluSxSINE,Alu
chr812879062TC0.00035KIAA1456+FALSE
chr373025345AG0.00219.FALSEAluSzSINE,Alu
chr1542860107AG0.00194HAUS2+TRUEAluSgSINE,Alu
chr1120612006GA0.00602NOTCH2-FALSE
chr117313654CT0.00714ATP13A2-FALSE
chr1145512024AG0.00247NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr315296357AT3.39714E-05SH3BP5,SH3BP5-AS1+,-FALSE
chr5180665123GA0.00259RACK1-FALSE
chr125644747TC0.00972RSRP1,RHD+,-FALSEAluSx1SINE,Alu
chr1145513112AG0.00080NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr3148748380TC0.00240HLTF-FALSE
chr1109818158CT0.00628CELSR2+FALSE
chr1911257673TC0.00211SPC24-TRUEAluSpSINE,Alu
chr1610623571TC0.00329EMP2-TRUEAluSpSINE,Alu
chr1205739266CT0.00069RAB29-FALSE
chr7100957851TC0.00028LOC101927746,IFT22+,-FALSEMADE1SINE,Alu
chr138327700TC0.00509INPP5B-TRUEAluSx3SINE,Alu
chr145987557GC0.00921PRDX1-FALSE
chr1110276861TC0.00180GSTM3-FALSELTR77SINE,Alu
chr18021778TC0.00495PARK7+FALSE
chr286252214TC0.00930POLR1A-TRUEAluSq2SINE,Alu
chr744841239TA0.00199PPIA+FALSE
chr352800284TC6.08396E-05NEK4-FALSE
chr6108214773CT0.00265SEC63-FALSE
chr417802976TC0.00146DCAF16-TRUEAluSzSINE,Alu
chr3195694454CT0.00307SDHAP1-FALSE
chr652267967AC0.00424PAQR8+FALSE
chr342826041TG0.00019HIGD1A-FALSE
chr345721922AG0.00181LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr7100860467CG0.00267PLOD3-FALSE
chr1765334967TC0.00045PSMD12-TRUEAluSqSINE,Alu
chr136068184TC0.00177PSMB2-TRUEAluScSINE,Alu
chr255516891GA2.12747E-05CCDC88A-FALSE(GA)nSINE,Alu
chr16282324TC0.00142ICMT-TRUEAluSzSINE,Alu
chr238971644TG0.00021SRSF7-FALSE
chr136031860GT0.00564NCDN+FALSE
chr110042987AG0.00488NMNAT1+TRUEAluScSINE,Alu
chr7100031495CT0.00475MEPCE+FALSE
chr119953131GA0.00486MINOS1,MINOS1-NBL1+FALSE
chr1179830012AC0.00303TOR1AIP2-FALSE
chr366024384GC0.00096MAGI1-FALSE
chr1450792961GA0.00547.FALSEAluSxSINE,Alu
chr261277798AG0.00077PEX13+TRUEAluYSINE,Alu
chr1173387540GA0.00438RAB6A-FALSE
chr12102517753TC0.00022PARPBP+FALSE
chr76064007TA0.00551EIF2AK1-FALSE
chr657034840TG0.00581ZNF451,LOC101927211+,-FALSE
chr35026730TC0.00488BHLHE40+FALSE
chr1288454641AT0.00753CEP290-FALSE
chr1156613401TC5.47226E-05BCAN+FALSE
chr110517513TC0.00982.FALSEAluSx1SINE,Alu
chr1565442112TC0.00529CLPX-TRUEAluSgSINE,Alu
chr3120114914GA1.07649E-06FSTL1-FALSE
chr537290416TC0.00162.FALSEAluSzSINE,Alu
chr764441627GA0.00478ZNF117-FALSE
chr1144822066AG0.00020NBPF20,NBPF9+FALSE
chr644417835AG8.27091E-07CDC5L+TRUEAluSxSINE,Alu
chr9133579734AG0.00129EXOSC2+TRUEAluSx3SINE,Alu
chr1538643574TC0.00455SPRED1+FALSE
chr1320247038AG0.00391MPHOSPH8+TRUEAluJbSINE,Alu
chr116890130AC0.00412NBPF1-FALSE
chr16583515TC0.00528NOL9-TRUEAluSqSINE,Alu
chr1101444069CA0.00962SLC30A7+FALSEMIR3SINE,Alu
chr3197612430AG0.00052.FALSEAluSpSINE,Alu
chr766421684TG0.00042TMEM248+FALSEAluJrSINE,Alu
chr127205359TC3.58613E-05.FALSEAluScSINE,Alu
chr2206986926TC0.00913.FALSEAluJrSINE,Alu
chr2172412008CG0.00982CYBRD1+FALSE
chr1075009921TC5.40286E-05DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr116890639CT5.60894E-05NBPF1-FALSE
chr1911256672TC9.28647E-11SPC24-TRUEAluJr4SINE,Alu
chr29661424GC0.00130ADAM17-FALSE
chr1737006249TC0.00774.FALSEAluSxSINE,Alu
chr2218571343AG0.00501PEX26+TRUEAluSzSINE,Alu
chr291843471CT0.00095LOC654342-FALSE
chr1144873887CT0.00088NBPF20,PDE4DIP+,-FALSE
chr3196658640CT0.00444SENP5+FALSE
chr2144331206AG0.00167.FALSEAluSzSINE,Alu
chr582877162GA0.00296VCAN+FALSE(A)nSINE,Alu
chr1215035081TC0.00951MGP-FALSE
chr4153545691TC0.00671.FALSEAluJbSINE,Alu
chr287883323AG0.00910.FALSE
chr1145513094AG0.00633NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1144606963GT0.00965NBPF20+FALSE
chr1911256689TC9.47404E-06SPC24-TRUEAluJr4SINE,Alu
chr838829416AG0.00695PLEKHA2+TRUEAluYcSINE,Alu
chr1341635235CT0.00400.FALSE
chr11666834GA0.00037SLC35E2-FALSEL1MEgSINE,Alu
chr2217498311TC0.00977IGFBP2+FALSE(CCG)nSINE,Alu
chr237330343CT0.00055.FALSEAluSq2SINE,Alu
chr4185309401AG0.00782IRF2-FALSE
chr6138734422CT0.00447HEBP2+FALSE
chr119586532AG0.00188MRTO4+TRUEAluSzSINE,Alu
chr436121337TA0.00065ARAP2-FALSE
chr8143763618CG0.00421PSCA+FALSE
chr3195412864GA0.00725SDHAP2+FALSE
chr237328013TC0.00364.FALSE
chrX3526659CG0.00188PRKX-FALSE(AC)nSINE,Alu
chr1118069696TC0.00170.FALSE
chr110042937AG2.41028E-05NMNAT1+TRUEAluScSINE,Alu
chr3197612430AG0.00095.FALSEAluSpSINE,Alu
chr830536437TC0.00062GSR-FALSEAluSpSINE,Alu
chr136067817TC0.00938PSMB2-TRUEAluSzSINE,Alu
chr112024235CT0.00395PLOD1+FALSE
chr1120458004AT0.00247NOTCH2-FALSE
chr116478619GA0.00656TRIM3-FALSE
chr552389811TG0.00561ITGA2+FALSE
chr1569803GA0.00166.FALSE
chr227170943AC0.00684DPYSL5+FALSE(CA)nSINE,Alu
chr1331033325CA0.00792HMGB1-FALSE
chr1680636297CG0.00161CDYL2-FALSE
chr1474388908TC0.00835ZNF410+FALSE
chr712250939GA0.00537TMEM106B+FALSE
chr371005566CT0.00209FOXP1-FALSE(T)nSINE,Alu
chr16582353TC0.00121NOL9-TRUEAluSx1SINE,Alu
chr119566382AG0.00513LOC101927895,EMC1+,-FALSE
chr1145695329AG0.00400NBPF20,NBPF10+FALSEAluSzSINE,Alu
chr1585184816TC3.05793E-06WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr1158067060TA0.00114KIRREL+FALSE
chr154355105AG0.00325YIPF1-FALSEMIRbSINE,Alu
chr314986104TC6.10128E-05FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1145322843CT0.00428NBPF20,NBPF10+FALSE
chr2176792531CT0.00779LNPK-FALSE
chr1063852210CT0.00324ARID5B+FALSE
chr1109780743CA0.00643SARS+FALSE
chr263817855CG0.00096MDH1+FALSE
chr1913883923AG0.00493MRI1+TRUEAluSzSINE,Alu
chr255459824CT0.00763RPS27A+FALSE
chr185785548CT0.00353DDAH1-FALSE
chr6150046734TC0.00248NUP43-FALSE
chr1143915879AC0.00097.FALSE
chr1149885583AG0.00030SV2A-FALSE
chr1424760808CT0.00203DHRS1-FALSE
chr264327544GT0.00340PELI1-FALSE
chr238971635CG0.00011SRSF7-FALSE
chr6160113872AG0.00863SOD2-FALSE
chr1172580637TC1.47330E-06SUCO+FALSE
chr1765335292TC6.31480E-06PSMD12-TRUEAluSxSINE,Alu
chr128920944AG0.00446RAB42+TRUEAluSxSINE,Alu
chr315113656TC1.73787E-06RBSN-TRUEAluSz6SINE,Alu
chr3150262002GT0.00016SERP1-FALSE
chr8145159712AG0.00402MAF1+FALSE
chr19160996TC0.00023.FALSEAluJbSINE,Alu
chr116945570AG0.00251CROCCP2-FALSE
chr1179042300CA0.00491FAM20B+FALSE
chr145987539CA0.00660PRDX1-FALSE
chr2206987635TC0.00930.FALSEAluJbSINE,Alu
chr3125033835TG0.00385ZNF148-FALSEAluJbSINE,Alu
chr1468117864AT0.00744ARG2+FALSE
chr1145689491AG0.00694NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr310193683TG0.00681VHL+FALSEAluJrSINE,Alu
chr627425185CA0.00577ZNF184-FALSE
chr439550612TC0.00023UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr348485452TA0.00363TMA7+FALSE
chr1204521631AG0.00024MDM4+TRUEAluSgSINE,Alu
chr119543353TC0.00091LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr5157185319AG0.00100LSM11+TRUEAluSqSINE,Alu
chr116893691CA0.00764NBPF1-FALSE
chr644222156AT0.00856SLC35B2-FALSE
chr1120612194CG0.00091NOTCH2-FALSE(CCG)nSINE,Alu
chr457327022AG0.00057PAICS+TRUEAluSx1SINE,Alu
chr110042988AG4.26240E-05NMNAT1+TRUEAluScSINE,Alu
chr4140310370TC0.00335NAA15+FALSE(T)nSINE,Alu
chr1171943768GT1.87744E-06INPPL1+FALSE
chr291805938AG0.00084.FALSEMLT1H1SINE,Alu
chr143996594TC0.00836PTPRF+FALSE(CGGCTC)nSINE,Alu
chr286251151TC0.00882.FALSEAluSxSINE,Alu
chr1145511983AG0.00596NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr540832549CT2.26031E-05RPL37-FALSE
chr4106767318AG1.71247E-06GSTCD+TRUEAluJbSINE,Alu
chr126755494AG0.00874LIN28A+TRUEAluScSINE,Alu
chr1144606963GT0.00080NBPF20+FALSE
chr3155658362CT0.00807.FALSEMIR3SINE,Alu
chr116890428TA0.00233NBPF1-FALSE
chr237479862CT0.00603PRKD3-FALSE
chr717384437AG0.00192AHR+TRUEAluSxSINE,Alu
chr1900720AT0.00204KLHL17+FALSE(TTTA)nSINE,Alu
chr195392593CT0.00173CNN3-FALSE(GGCGCG)nSINE,Alu
chr314986471TC3.70393E-05FGD5-AS1-TRUEAluSq2SINE,Alu
chr116889413TC8.21040E-06NBPF1-TRUEL1MC4SINE,Alu
chr1204525713AG0.00501MDM4+TRUEAluSzSINE,Alu
chr357612271TC0.00831DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr139470978TA0.00378AKIRIN1+FALSEAluSx1SINE,Alu
chr642856924AG2.08684E-05RPL7L1+TRUEAluSpSINE,Alu
chr388199298TC0.00112C3orf38+FALSE
chr1224517842CT0.00014NVL-FALSE
chr1148594563GT0.00169NBPF15+FALSE
chr121795388AG0.00790NBPF3+FALSE
chr1585185205TC0.00459WDR73,SCAND2P+,-FALSEFLAM_CSINE,Alu
chr1073994158AG0.00110ANAPC16+TRUEAluJrSINE,Alu
chr133149260AG0.00143SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1545775144TC0.00867SLC30A4-TRUEAluJrSINE,Alu
chr1738798073TG0.00692SMARCE1-FALSE
chr5125961455AG0.00029PHAX+TRUEAluSz6SINE,Alu
chr192917287CA0.00243ZNF57+FALSE
chr2202028727AG0.00833CFLAR+TRUEAluSx1SINE,Alu
chr16704635AG0.00978DNAJC11-FALSE
chr153289860AG0.00041ZYG11B+TRUEFRAMSINE,Alu
chr178142856TC0.00086ZZZ3-TRUEAluSxSINE,Alu
chr1161929879AT0.00680ATF6+FALSE
chr1583826212CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr193827995CT0.00236DR1+FALSE
chr133148698AG0.00736SYNC,RBBP4+,-FALSEAluScSINE,Alu

Differential Expression Gene Analysis