Dataset Overview
RBPUPF1
Knock-MethodshRNA
RBP FamilyUPF1_Zn_bind
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR251ABP
PlatformHiSeq
Pubmed ID32252787

UPF1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of UPF1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of UPF1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1574319092AG0.00029PML+TRUEAluSz6SINE,Alu
chr642855967AG0.00151RPL7L1+TRUEAluSzSINE,Alu
chrX3526615GT0.00820PRKX-FALSE
chr1144014068TC0.00029.FALSE
chr10117823566GT0.00433GFRA1-FALSE(ATC)nSINE,Alu
chr167874849TC0.00169SERBP1-TRUEAluSxSINE,Alu
chr110517688TC0.00020.FALSEAluSx1SINE,Alu
chr5125961447AG0.00242PHAX+TRUEAluSz6SINE,Alu
chr11337737GC2.51903E-05MRPL20-FALSE
chr127202981TC0.00660.FALSEAluSq2SINE,Alu
chr2128950515AG0.00208UGGT1+TRUEAluScSINE,Alu
chr1947278340AG0.00449SLC1A5-FALSE(AC)nSINE,Alu
chr296915238TC2.48142E-05.FALSEAluJrSINE,Alu
chr120977380TC0.00429PINK1,PINK1-AS+,-FALSE
chr1762541203GA0.00660SMURF2-FALSE
chr1148752615CA0.00042.FALSE
chr1741144581AC0.00806RUNDC1+FALSEAluSxSINE,Alu
chr1117530213GT0.00256PTGFRN+FALSE
chr1745761108GT0.00127.FALSE
chr110520180TC0.00959.FALSEAluSxSINE,Alu
chr111084103TA0.00044TARDBP+FALSE
chr3183861243AG0.00049EIF2B5+FALSE
chr613790888TC0.00442MCUR1-TRUEAluSx1SINE,Alu
chr1226171340TC0.00462SDE2-TRUEBC200SINE,Alu
chr1111489903AC0.00666LRIF1-FALSE
chr1810691357GA0.00082PIEZO2-FALSE
chr1214529320TG0.00365PTPN14-FALSEAluJbSINE,Alu
chr2128061053AG0.00184MAP3K2-FALSE
chr837613073AC0.00394ERLIN2+FALSE(CCCCCAC)nSINE,Alu
chr1182358196CG0.00929GLUL-FALSE
chr1206566195CT0.00334SRGAP2+FALSE
chr1109351501AG0.00921STXBP3+FALSE
chr140537944CA0.00371CAP1+FALSE
chr6160526904TG0.00027IGF2R+FALSE
chr131345785TA0.00962SDC3-FALSE
chr1748771488CA0.00148ANKRD40-FALSEAluSzSINE,Alu
chr13545194CG0.00176TPRG1L+FALSE
chr1911256689TC9.47404E-06SPC24-TRUEAluJr4SINE,Alu
chr110517314TC0.00286.FALSEAluJrSINE,Alu
chr16282318TC0.00418ICMT-TRUEAluSzSINE,Alu
chr12113565TG0.00429PRKCZ+FALSE
chr2202030111AG0.00983CFLAR+TRUEAluSx1SINE,Alu
chr1119427687GC0.00823TBX15-FALSE
chr122852880GC0.00247ZBTB40+FALSE
chr495586725TA0.00743PDLIM5+FALSE
chr270316299CA0.00650PCBP1+FALSE
chr119934838CT2.17786E-05MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr6150047362TC0.00076NUP43-TRUEAluScSINE,Alu
chr1155217438AT0.00610FAM189B-FALSE
chr1610625414TC0.00015EMP2-TRUEAluSxSINE,Alu
chr2203742141TC0.00044.FALSEAluJbSINE,Alu
chr12125114CT8.70493E-12FAAP20-FALSE
chr2198572083TA0.00272MARS2+FALSE
chr1913884084AG0.00843MRI1+TRUEAluSzSINE,Alu
chr124086807TC0.00352TCEB3+FALSE(T)nSINE,Alu
chr135652608AG0.00026SFPQ-FALSE
chr1757281098AG0.00181PRR11+TRUEAluSzSINE,Alu
chr3122283290GC0.00029DTX3L,PARP9+,-FALSE
chr937503490AG0.00612POLR1E+TRUEAluJbSINE,Alu
chr110520683TC0.00457DFFA-TRUEAluSc8SINE,Alu
chr210567337GC0.00940HPCAL1+FALSE
chr2132275343GT0.00334LOC150776+FALSE
chr6150046601TC0.00073NUP43-TRUEAluSq2SINE,Alu
chr261764922GC0.00679XPO1-FALSE
chr342253664CT0.00065TRAK1+FALSE
chr2118854086GC0.00066INSIG2+FALSE
chr1610623544TC2.29348E-06EMP2-TRUEAluSpSINE,Alu
chr1075008876TC0.00255DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr1203711876GA0.00444ATP2B4+FALSE
chr116974666CT0.00131MST1P2+FALSE
chr1246829873GA0.00342CNST+FALSE
chrX2824979TC0.00049ARSD-TRUEAluSx1SINE,Alu
chr13550061AC0.00000WRAP73-FALSE
chr1184761350TC0.00754FAM129A-TRUEAluJoSINE,Alu
chr1145689717AG3.41980E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr644222158TA0.00781SLC35B2-FALSE
chr111979815AC0.00072KIAA2013-FALSE
chr101086801GC0.00421IDI2-AS1,IDI1+,-FALSE
chr193827764AG0.00056DR1+FALSE
chr128920944AG0.00446RAB42+TRUEAluSxSINE,Alu
chr128832533GA0.00761SNHG3,RCC1+FALSE
chr12123346997GC0.00275HIP1R+FALSE
chr126900708GA0.00349RPS6KA1+FALSE
chr310290515GA0.00904TATDN2+FALSE
chr11417974CT0.00677ATAD3B+FALSE
chr1225360463AT0.00118KRAS-FALSE
chr1145369589TC0.00128NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr119543282TC0.00020LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2203741065TC2.92684E-06.FALSE
chr1204526710AG0.00082MDM4+TRUEAluSxSINE,Alu
chr146828653TA0.00920NSUN4+FALSE
chr1089004545TC0.00057NUTM2A-AS1-FALSEMSTASINE,Alu
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr1346530764TG0.00385.FALSE
chr220401855GA0.00107SDC1-FALSE
chr144423703CT1.17684E-14IPO13+FALSE
chr111785182AG0.00262.FALSEAluJrSINE,Alu
chr16257826TC0.00560RPL22-FALSE
chr344790624TC0.00150KIAA1143-TRUEAluYSINE,Alu
chr237331531TC0.00063.FALSEAluJbSINE,Alu
chr1585185205TC0.00459WDR73,SCAND2P+,-FALSEFLAM_CSINE,Alu
chr2133974092GC0.00865C21orf59-FALSE
chr315113655TC6.08503E-07RBSN-TRUEAluSz6SINE,Alu
chr1145116027TC1.71852E-07NBPF20,SEC22B+FALSE
chr642855962AG0.00781RPL7L1+TRUEAluSzSINE,Alu
chr556177872AG0.00618MAP3K1+TRUE(CAA)nSINE,Alu
chr5140798639GC3.89156E-05PCDHGA1,PCDHGA2,PCDHGA3,PCDHGB1,PCDHGA4,PCDHGB2,PCDHGA5,PCDHGB3,PCDHGA6,PCDHGA7,PCDHGB4,PCDHGA8,PCDHGB5,PCDHGA9,PCDHGB6,PCDHGA10,PCDHGB7+FALSE
chr254896391CT0.00162SPTBN1+FALSE
chr227315252GA0.00377KHK+FALSE
chr63021492AG0.00613HTATSF1P2-FALSETigger3aSINE,Alu
chr119585917TA0.00308MRTO4+FALSEAluJrSINE,Alu
chrX123045103AG0.00996XIAP+TRUEAluSpSINE,Alu
chr1226333556CA0.00977ACBD3-FALSE(CAAAA)nSINE,Alu
chr568850966GT0.00134OCLN+FALSEAluSx4SINE,Alu
chr2206983267TC0.00133.FALSEAluJbSINE,Alu
chr2201842323TC0.00254FAM126B-TRUEAluJbSINE,Alu
chr138423205AG0.00923SF3A3-FALSEAluJoSINE,Alu
chr11152631CA0.00517SDF4-FALSE
chr167874696TC0.00839SERBP1-TRUEAluSx3SINE,Alu
chr871550832TC0.00725LACTB2-AS1,LACTB2+,-FALSE
chr124989266AT0.00392SRRM1+FALSE
chr1160966299TC0.00033F11R-TRUEAluSgSINE,Alu
chr1757279167AG0.00071PRR11+TRUEAluSq2SINE,Alu
chr7102119322TC0.00834POLR2J-FALSE
chr2189877304AT0.00612COL3A1+FALSE
chr12133298019AG2.77684E-05PGAM5+TRUEAluJoSINE,Alu
chr1450053350TA0.00071.FALSE7SLRNASINE,Alu
chr9131872853CG0.00108CRAT-FALSE
chr1789232CT0.00335LINC01128+FALSE
chr146075171AC0.00280NASP+FALSEA-richSINE,Alu
chr1453109677TC5.62031E-05ERO1A-FALSE
chr237329300TC0.00590.FALSEAluJr4SINE,Alu
chr153366673AG0.00243ECHDC2-FALSEAluJbSINE,Alu
chr187213177CA0.00020SH3GLB1+FALSE
chr1110136321TA0.00721GNAI3+FALSE
chr133147722GA1.17176E-11SYNC,RBBP4+,-FALSE
chr128835937AG0.00121SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr132697063TC0.00035EIF3I+FALSEAluSpSINE,Alu
chr2203744629TC0.00363.FALSEAluSx1SINE,Alu
chr1182569291AT0.00979RGS16-FALSE
chr5121362874AG0.00607SRFBP1+TRUEFRAMSINE,Alu
chr1212910930GA2.01027E-05NSL1-FALSE
chr129848629AG0.00027CLEC2D+FALSE
chr2146353985AG0.00985LINC01547-FALSEMER5ASINE,Alu
chr2151326173AC0.00143RND3-FALSE
chr5170832637CT0.00071NPM1+FALSE
chr613788222TC0.00490MCUR1-TRUEAluSxSINE,Alu
chr2128603087TC0.00036.FALSEAluSpSINE,Alu
chr237331019TC0.00597.FALSEAluSx1SINE,Alu
chr3148863151AG0.00062HPS3+FALSE
chr3195461463AG0.00609.FALSEAluJbSINE,Alu
chr12133297934AG9.03426E-06PGAM5+TRUEAluJoSINE,Alu
chr1218617543GA0.00291TGFB2+FALSE
chr5179020622TC2.11448E-05RUFY1+FALSE
chr1145283733AG0.00458NBPF20,NOTCH2NL+FALSE
chr6116256595CA5.71236E-05.FALSE
chr1931935TC0.00796.FALSE
chr9111779229TC0.00269TMEM245-FALSE
chr2217366896AG0.00457.FALSEAluSz6SINE,Alu
chr765844062TA0.00733LINC00174-FALSE
chr690344605TC0.00013LYRM2-TRUEAluSz6SINE,Alu
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr825272364CG0.00693DOCK5+FALSE
chr119543973TC0.00236LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr674134744TC0.00214.FALSEAluSzSINE,Alu
chr310065426CT0.00776CIDECP-FALSE
chr237331525TC0.00020.FALSEAluJbSINE,Alu
chr153680090GA0.00321C1orf123-FALSE
chr1224302047CT3.20569E-05FBXO28+FALSE
chr16282400TC0.00601ICMT-TRUEAluSzSINE,Alu
chr543700242AG0.00932NNT+FALSE
chr112071680AG5.54475E-07MFN2+FALSE
chr1541590287AG0.00319OIP5-AS1+FALSE
chr237328008TC0.00733.FALSE
chr193297605CG0.00319RPL5+FALSE
chr2152334421AG0.00464.FALSEAluSqSINE,Alu
chr2043996145TA0.00611SYS1-DBNDD2,SYS1+FALSE
chr333138549GA0.00612GLB1-FALSE
chr13730400TC0.00894CEP104-TRUEAluSx3SINE,Alu
chr1015120179TC3.12210E-06ACBD7-FALSEL1PA7SINE,Alu
chr18412989AG0.00225RERE-FALSE
chr146828700AG0.00273NSUN4+FALSE
chr1211921702TC0.00014LPGAT1-FALSE
chr2183643241CA0.00108DNAJC10+FALSE
chr1117644949CG0.00440TTF2+FALSE
chr1619715588TC0.00063.FALSEAluSgSINE,Alu
chr197144750TC0.00262.FALSE
chr115899630TC0.00082AGMAT-TRUEAluSq2SINE,Alu
chr132833540TC0.00381BSDC1-TRUE
chr1779674375CT0.00129MRPL12+FALSE
chr119542631TC0.00176LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr232532809AG0.00255.FALSEAluSx1SINE,Alu
chr110517613TC0.00375.FALSEAluSx1SINE,Alu
chr1533064791GA0.00203FMN1-FALSE
chr1214524531TC0.00753PTPN14-TRUEAluSgSINE,Alu
chr1179327008AG0.00168SOAT1+TRUE
chr11573181CA0.00038CDK11B-FALSE
chr540832553AT9.00390E-07RPL37-FALSE
chr12125511226AG0.00205THRIL-FALSEAluSx1SINE,Alu
chr722981942GA0.00041FAM126A-FALSE
chr1190234133AC5.13910E-06BRINP3-FALSE
chr185787118GC0.00104DDAH1-FALSE
chr126161104CA0.00030AUNIP-FALSEAluSc8SINE,Alu
chr110042955AG0.00131NMNAT1+TRUEAluScSINE,Alu
chr457326262AG2.33397E-05PAICS+TRUEAluJrSINE,Alu
chr1118552269TA0.00066.FALSEAluJrSINE,Alu
chr1590819418AG0.00516.FALSEAluSxSINE,Alu
chr1200521412GA0.00110KIF14-FALSE
chr7156764350GC0.00415NOM1+FALSE
chr1203821865CT0.00222ZC3H11A+FALSE
chr185785550CA0.00134DDAH1-FALSE
chr1583659311CT0.00858FAM103A1,C15orf40+,-FALSE
chr16583593TC0.00088NOL9-TRUEAluSqSINE,Alu
chr10120795222AT0.00193EIF3A-FALSE
chr144088117GT0.00731PTPRF+FALSE(T)nSINE,Alu
chr919373161AG0.00647DENND4C+TRUEMADE1SINE,Alu
chr1109967951AC0.00095PSMA5-FALSE
chr42517223AG2.74855E-08RNF4+FALSE
chr1610623706TC0.00064EMP2-TRUEAluSpSINE,Alu
chr1773940094TC0.00557ACOX1-TRUEAluJbSINE,Alu
chr1773940077TC0.00146ACOX1-TRUEAluJbSINE,Alu
chr438945689CT1.01800E-05FAM114A1+FALSEAluScSINE,Alu
chr514696117TC0.00807OTULIN+FALSE
chr1183094547TC0.00277LAMC1+FALSE
chr119543797TC0.00754LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr264687665CA0.00976LGALSL+FALSE
chr19732611TC0.00321PIK3CD,PIK3CD-AS2+,-FALSEAluJoSINE,Alu
chr12133298417AG6.66134E-16PGAM5+TRUEAluSpSINE,Alu
chr136067838TC0.00081PSMB2-TRUEAluSzSINE,Alu
chr4248783AG0.00901ZNF876P+FALSEL1MA3SINE,Alu
chr265496144AG0.00883ACTR2+FALSE
chr1145368665GA0.00031NBPF20,NBPF10+FALSE
chr1144931392GA0.00241NBPF20,PDE4DIP+,-FALSE
chr1237064432CG0.00019MTR+FALSE
chr178414285TA0.00256FUBP1-FALSE
chr17421931TC0.00260VPS53-TRUEAluSxSINE,Alu
chr574072648TA0.00036NSA2+FALSE
chr110517659TC0.00010.FALSEAluSx1SINE,Alu
chr315296357AT3.39714E-05SH3BP5,SH3BP5-AS1+,-FALSE
chr110520672TC0.00584DFFA-TRUEAluSc8SINE,Alu
chr136068278TC0.00068PSMB2-TRUEAluScSINE,Alu

Differential Expression Gene Analysis