Dataset Overview
RBPEXOSC9
Knock-MethodshRNA
RBP FamilyRNase_PH
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR597IYB
PlatformHiSeq
Pubmed ID32252787

EXOSC9 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EXOSC9
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EXOSC9


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr128906337AG0.00810SNHG12,SNORA61-FALSE
chr388104158TA0.00971CGGBP1-FALSE
chr2183643905AT0.00113DNAJC10+FALSE
chr126158908GC0.00181MTFR1L,AUNIP+,-FALSE
chr1179044206AG0.00458FAM20B+TRUEAluSxSINE,Alu
chr1110049203GC0.00209.FALSE
chr1767538540TC0.00295.FALSE
chr1155106227AT0.00214EFNA1+FALSE
chr154691921GA0.00010SSBP3-FALSE
chr3179117663GC6.59793E-05GNB4-FALSE
chr1115259768TC0.00156CSDE1-FALSE
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr167896025GA5.77574E-06SERBP1-FALSE
chr153288862AG0.00503ZYG11B+TRUEAluJoSINE,Alu
chr110518037TC0.00017.FALSEAluJrSINE,Alu
chr224223256AG0.00711UBXN2A+TRUEAluScSINE,Alu
chr366419942AG0.00284SLC25A26+FALSE
chr1161488402TA0.00083FCGR2A+FALSE
chr811172477CT0.00805MTMR9+FALSE
chr3195412864GA0.00725SDHAP2+FALSE
chr2228421461GC0.00069AGFG1+FALSE
chr442091668AG0.00430.FALSEAluSpSINE,Alu
chr3133538762AT0.00804SRPRB+FALSE
chr144415424AG0.00213IPO13+FALSE
chr126755303AG0.00129LIN28A+TRUEAluSx1SINE,Alu
chr175288079AC0.00085RABEP1+FALSE
chr3137787192TC0.00764DZIP1L-FALSE
chr2202242616GA0.00880TRAK2-FALSE
chr1958375157AG0.00408ZNF587+TRUEAluSx4SINE,Alu
chr16283306TC0.00275ICMT-TRUEAluSx3SINE,Alu
chr13545200GA0.00676TPRG1L+FALSE
chr119586520AG0.00659MRTO4+TRUEAluSzSINE,Alu
chr220449068AG0.00014PUM2-FALSE
chr127045885AC0.00473ATN1+FALSE(CAG)nSINE,Alu
chr439549701TC0.00269UGDH-AS1,SMIM14+,-FALSEAluSpSINE,Alu
chr128858860CT0.00213RCC1+FALSE
chr579923360TC0.00727DHFR-TRUEAluJrSINE,Alu
chr2176790393CT0.00282LNPK-FALSEAluSpSINE,Alu
chr237331627TC0.00910.FALSEAluJbSINE,Alu
chr19642827GA0.00521SLC25A33+FALSE
chr1591044383GT0.00440IQGAP1+FALSE
chr1765334828TC0.00160PSMD12-TRUEAluSqSINE,Alu
chr125894471GA0.00778LDLRAP1+FALSEMIRbSINE,Alu
chr28996878AT9.26766E-05MBOAT2-FALSEAluSzSINE,Alu
chr123636274GT0.00165HNRNPR-FALSE
chr133148096AG0.00404SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1939926509AC0.00986RPS16-FALSE
chr191863170GA0.00204KLF16-FALSE
chr356763328TC0.00546ARHGEF3-FALSE
chr133068221AG0.00448ZBTB8A+TRUEAluYSINE,Alu
chr1120611964GC0.00130NOTCH2-FALSE
chr1169824104GA0.00744SCYL3-FALSE
chr8144357992AG0.00780GLI4+FALSE
chr3156259317TC0.00189SSR3-TRUEAluSq2SINE,Alu
chr19643054AG5.80579E-05.FALSEAluSxSINE,Alu
chr3167727417CT2.31470E-08GOLIM4-FALSE
chr2232319583CA0.00801NCL-FALSEA-richSINE,Alu
chr3124948049TC0.00709ZNF148-TRUE
chr1399056476AT0.00535FARP1+FALSE
chr237429737AG0.00549CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr1182356399AG0.00740GLUL-FALSE
chr111347150CA0.00016UBIAD1+FALSE
chr711148863TA0.00455PHF14+FALSE
chr199673113TC0.00330.FALSEAluSx3SINE,Alu
chr116893721AC0.00043NBPF1-FALSE
chr192862836AG0.00430.FALSEAluJrSINE,Alu
chr2204301754CG0.00012RAPH1-FALSE
chr110221287AG0.00961UBE4B+FALSE
chr1321547676TC0.00403LATS2-FALSE
chr224225006AG0.00277.FALSEAluSxSINE,Alu
chr116921146TC0.00353NBPF1-FALSE
chr2204162277AG0.00097CYP20A1+TRUEAluSxSINE,Alu
chr2128602455TC0.00632.FALSEAluSq2SINE,Alu
chr626368938CT0.00121BTN3A2+FALSE
chr3196728813CT0.00068MELTF-FALSE
chr1179041705AT0.00068FAM20B+FALSE
chr110042988AG0.00095NMNAT1+TRUEAluScSINE,Alu
chrX102613351AG0.00969TCEAL9+FALSEL1ME4aSINE,Alu
chr717384440AG0.00271AHR+TRUEAluSxSINE,Alu
chr1332973012AC0.00231BRCA2+FALSE
chr72473761TC0.00126CHST12+FALSE(CCGC)nSINE,Alu
chr124864008AG0.00601.FALSE
chr42517223AG2.74855E-08RNF4+FALSE
chr5180663940AG0.00331RACK1-FALSE
chr144171144TA0.00108KDM4A-AS1,KDM4A+,-FALSE
chr192975244TA0.00220EVI5-FALSE
chr1138156GT0.00413LOC729737-FALSE
chr1234744480GA0.00237IRF2BP2-FALSE
chr237429733AG0.00381CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr1173863209GA0.00156.FALSE
chr439551087TC0.00263UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr5178986978CG0.00341RUFY1+FALSE
chr1161932324AG0.00056ATF6+FALSE
chr128826130AG1.79185E-05PHACTR4+TRUEAluJbSINE,Alu
chr11344749AG0.00307.FALSEAluSx1SINE,Alu
chr1114940210TG0.00028TRIM33-FALSE(T)nSINE,Alu
chr133148225AG0.00031SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr193803490TC0.00572CCDC18-AS1-FALSEAluJrSINE,Alu
chr717384393AG1.74996E-06AHR+TRUEAluSxSINE,Alu
chr12133297966AG0.00000PGAM5+FALSEAluJoSINE,Alu
chr1145282904AG0.00542NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr211966317TC0.00011LPIN1+FALSE
chr1180082720GA0.00577CEP350+FALSE
chr2218571431AG0.00158PEX26+TRUEAluSzSINE,Alu
chr195362949AT0.00012CNN3-FALSE(A)nSINE,Alu
chr114159457AG0.00764RRM1+FALSE
chr534906750TC0.00527RAD1-TRUEAluJoSINE,Alu
chr7123390058AG0.00102.FALSE
chr2217366919AG0.00480.FALSEAluSz6SINE,Alu
chr135646125CT0.00027SFPQ-FALSE
chr345722381AG0.00996LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr1179044100AG0.00897FAM20B+TRUEAluSxSINE,Alu
chr1194801633AT0.00808SRSF8+FALSE
chr1015120279TC0.00255ACBD7-TRUEL1PA7SINE,Alu
chr1229439639TA0.00276RAB4A+FALSE
chr1185069561AG0.00675RNF2+FALSE
chr365341374TA0.00029MAGI1-FALSE
chr1144595943AG0.00050NBPF20+FALSEAluJbSINE,Alu
chr3195451488CT1.73907E-06MUC20+FALSE
chr126774224AG0.00295DHDDS+TRUEAluSz6SINE,Alu
chr1156163906CT0.00130SLC25A44+FALSE
chr116932809CT0.00887NBPF1-FALSEL1MC2SINE,Alu
chr2219460472TC0.00187CNOT9+FALSE
chr271376999GA0.00546MPHOSPH10+FALSE
chr2180810264AT1.24157E-05CWC22-FALSE
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr11594977TC0.00075CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr1913884422AG0.00878MRI1+TRUEAluJrSINE,Alu
chr1109816293GC0.00759CELSR2+FALSE
chr116893841CT0.00272NBPF1-FALSE
chr110517527TC0.00430.FALSEAluSx1SINE,Alu
chr11721936GA0.00731GNB1-FALSE
chr146076481AG0.00144NASP+TRUEAluSxSINE,Alu
chr128835934AG3.31538E-06SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr11595540TC0.00830CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr2217366933CT2.15691E-05.FALSEAluSz6SINE,Alu
chr561683960AG0.00491.FALSE
chr626095642AG0.00332.FALSEAluYSINE,Alu
chr1205683408CT0.00082NUCKS1-FALSE
chr146075709AG0.00431NASP+TRUEAluSx4SINE,Alu
chr1225683182CT0.00056ENAH-FALSE
chr2204162036AG0.00369CYP20A1+TRUEAluSxSINE,Alu
chr11251847TC0.00999CPSF3L-FALSEAluSq2SINE,Alu
chr254896390GT0.00110SPTBN1+FALSE
chr1179326418AG0.00626SOAT1+TRUEAluSgSINE,Alu
chr152381354GT0.00157RAB3B-FALSE
chr537288767TC0.00928.FALSEFLAM_CSINE,Alu
chr1544055281TC0.00580PDIA3+FALSE
chr12123346997GC0.00275HIP1R+FALSE
chr285824712CA0.00663RNF181+FALSE
chr1668962CT0.00852.FALSE
chr193465142TC0.00100NFIC+FALSE
chr18045340CA0.00217PARK7+FALSE
chr1144922583GA0.00101NBPF20,PDE4DIP+,-FALSE
chr174672474GA0.00292FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr1788795TG0.00333LINC01128+FALSECharlie19aSINE,Alu
chr146078630AG4.65755E-11NASP+FALSE
chr1234744480GA0.00409IRF2BP2-FALSE
chr1145513114AG0.00033NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr136068166TC0.00686PSMB2-TRUEAluScSINE,Alu
chr3124732406CA0.00975HEG1-FALSE
chr1162752670GA0.00594.FALSE
chr11419130AG0.00685ATAD3B+FALSEAluSzSINE,Alu
chr1296661613AG0.00183ELK3+FALSE
chr1899810GA3.12519E-10KLHL17+FALSE
chr133145989AT0.00548SYNC,RBBP4+,-FALSE
chr3195415493CT0.00126LINC00969,SDHAP2+FALSEL1ME2SINE,Alu
chr2134729931AG0.00040IFNAR1+TRUEAluSg7SINE,Alu
chr337031951GA0.00154EPM2AIP1-FALSE(A)nSINE,Alu
chr110518733TC0.00399.FALSEAluSx1SINE,Alu
chr1145273345TC0.00640NBPF20,NOTCH2NL+FALSE
chr110520888CT0.00960DFFA-FALSE
chr4190873405CT0.00325FRG1+FALSE
chr11337734CT3.46713E-05MRPL20-FALSE
chr110520692TC0.00973DFFA-TRUEAluSc8SINE,Alu
chr1176733945AT0.00931ACER3+FALSEA-richSINE,Alu
chr191990450AT0.00405CDC7+FALSELFSINE_VertSINE,Alu
chr1117910682GA0.00013MAN1A2+FALSE
chr1939433138GA0.00276FBXO17-FALSEAluJbSINE,Alu
chr288895123TC0.00706EIF2AK3-FALSE
chr140537924GA0.00245CAP1+FALSE(A)nSINE,Alu
chr136642420TC0.00358MAP7D1+FALSE
chr119934900GA0.00605MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr220424655GA0.00193SDC1-FALSE
chr116259813AG0.00475SPEN+FALSE
chr187573331TC0.00699HS2ST1+FALSE(AT)nSINE,Alu
chr210198113CA0.00893CYS1-FALSE
chr1145689717AG0.00696NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr299772813AG1.48642E-06LIPT1+TRUEAluSx1SINE,Alu
chr1185069687CT0.00072RNF2+FALSE
chr1138156GT0.00140LOC729737-FALSE
chr1145511998AG0.00715NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr272968438GT0.00147EXOC6B-FALSE
chr7299843GA6.16222E-05FAM20C+FALSE
chr471682381TC0.00037GRSF1-TRUEAluSz6SINE,Alu
chr1207943211GA0.00248CD46+FALSEAluSx1SINE,Alu
chr16283264TC0.00521ICMT-TRUEAluSx3SINE,Alu
chr154692334TC0.00021SSBP3-FALSE(T)nSINE,Alu
chr1939433141AG0.00224FBXO17-FALSEAluJbSINE,Alu
chr1591044385GT0.00440IQGAP1+FALSE
chr3101542436AG0.00023NXPE3+TRUEAluJrSINE,Alu
chr2206983491TC0.00505.FALSEAluSxSINE,Alu
chr132799434CT0.00227MARCKSL1-FALSE
chr119542458TC6.76498E-05LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr11549354GA0.00383.FALSEHAL1SINE,Alu
chr2234386018AG0.00299USP40-FALSE
chr16259433GA0.00522RPL22-FALSEG-richSINE,Alu
chr722983890TC0.00097FAM126A-FALSE
chr537290335TC1.49367E-06.FALSEAluSzSINE,Alu
chr5125961166AG0.00732PHAX+TRUEAluSzSINE,Alu
chr18931947TC0.00059ENO1-FALSE
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr2208619461AG2.24939E-05CCNYL1+TRUEFAMSINE,Alu
chr1142803764CT1.49403E-06.FALSEMIRbSINE,Alu
chr1223178477CT0.00519DISP1+FALSE
chr119586501AG0.00055MRTO4+TRUEAluSzSINE,Alu
chr116841972GA1.76809E-05.FALSEMER41ESINE,Alu
chr110521238TC0.00173DFFA-TRUEAluYSINE,Alu
chr5125961204AG0.00196PHAX+TRUEAluSzSINE,Alu
chr310192709CT0.00082VHL+FALSEAluSx1SINE,Alu
chr136068364TC0.00195PSMB2-TRUEAluScSINE,Alu
chr11597423CT1.10134E-13CDK11B,SLC35E2B-FALSE
chr344791293AT0.00031KIAA1143-FALSEAluJrSINE,Alu
chr119586520AG0.00305MRTO4+TRUEAluSzSINE,Alu
chr136067760TC0.00044PSMB2-TRUEAluSzSINE,Alu
chr1610623543TC0.00025EMP2-TRUEAluSpSINE,Alu
chr5154194456GC0.00831LARP1+FALSE
chr237329300TC0.00590.FALSEAluJr4SINE,Alu
chr341281407GT0.00288CTNNB1+FALSE
chr1109746601AG0.00024KIAA1324+TRUEAluJbSINE,Alu
chr177166017GA0.00146.FALSE
chr310005392TC8.76084E-06EMC3-FALSEAluSg7SINE,Alu
chr1564657530TC0.00580KIAA0101-TRUEFLAM_CSINE,Alu
chr2217366192TA0.00067.FALSE
chr131902343TC1.48709E-05SERINC2+FALSE
chr13703611AC0.00208LRRC47-FALSE
chr3179117242TC0.00011GNB4-TRUEAluSzSINE,Alu
chr197543764CT0.00901DPYD-FALSE
chr274090062TG0.00248STAMBP+FALSE
chr1379188534TA0.00698RNF219-AS1,RNF219+,-FALSE
chr2198368110CA0.00053HSPE1,HSPE1-MOB4+FALSE
chr195123291GC0.00040LINC01057-FALSELTR7YSINE,Alu
chr286249961TC0.00262LOC90784-TRUEAluJrSINE,Alu

Differential Expression Gene Analysis