Dataset Overview
RBPFASTKD2
Knock-MethodshRNA
RBP FamilyRAP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR608IAI
PlatformHiSeq
Pubmed ID32252787

FASTKD2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of FASTKD2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of FASTKD2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr110520439TC0.00293.FALSEAluSx1SINE,Alu
chr189447882AG0.00103KYAT3,RBMXL1-FALSE
chr2218571475AG0.00019PEX26+TRUEAluSzSINE,Alu
chr3196077460GT0.00416.FALSE
chr178378694AC0.00735MYH10-FALSE
chr1293192790GT0.00161EEA1-FALSE
chr115909744CT0.00225AGMAT-FALSE
chr124288529TC0.00401PNRC2+FALSE
chr23609064GA0.00194RNASEH1-AS1+FALSEMER33SINE,Alu
chr9131071533TC0.00168TRUB2-TRUEFAMSINE,Alu
chr116893686GC0.00171NBPF1-FALSE
chr154354935GC0.00831YIPF1-FALSE
chr165147002CT6.62669E-07CACHD1+FALSE
chr1120162787TC0.00925ZNF697-FALSE
chr120976163CT0.00174PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr111979814GA0.00697KIAA2013-FALSE
chr11017747AG0.00142C1orf159-FALSE
chr417802956TC0.00351DCAF16-TRUEAluSzSINE,Alu
chr126765033AG0.00324DHDDS+TRUEAluJrSINE,Alu
chr11252652TC0.00219CPSF3L-TRUEAluSpSINE,Alu
chr128835937AG0.00181SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr4190883001CG0.00319FRG1+FALSE
chr41388115CG0.00682CRIPAK+FALSEL1MB4SINE,Alu
chr133148287AG0.00052SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr349067809TA0.00022QRICH1-FALSE
chr12125511242AG0.00015THRIL-FALSEAluSx1SINE,Alu
chr2206986978TC0.00159.FALSEAluJrSINE,Alu
chr1566933AG3.50078E-05.FALSE
chr237333930TC0.00073EIF2AK2-FALSEAluSzSINE,Alu
chr132706126GA0.00932MTMR9LP-FALSE
chr1145293566GA0.00103NBPF20,NBPF10+FALSE
chr1181058313GA0.00651IER5+FALSE
chr3179042910AG0.00061ZNF639+TRUEAluSpSINE,Alu
chr110519947TC0.00323.FALSEAluJrSINE,Alu
chr128836975AG0.00202SNHG3,RCC1+TRUEAluScSINE,Alu
chr1168220489AG0.00126.FALSEAluSz6SINE,Alu
chr1936575645GA0.00590WDR62+FALSE
chr441956313AG0.00710TMEM33+FALSE
chr237331525TC0.00020.FALSEAluJbSINE,Alu
chr128826118AG0.00023PHACTR4+TRUEAluJbSINE,Alu
chr146828700AG0.00273NSUN4+FALSE
chr18413129GA0.00040RERE-FALSE
chr167874696TC0.00839SERBP1-TRUEAluSx3SINE,Alu
chr133240842CT0.00446YARS-FALSE
chr1688789699AC0.00936PIEZO1-FALSE
chr1145273345TC0.00133NBPF20,NOTCH2NL+FALSE
chr1144014068TC0.00029.FALSE
chr1088729314CT8.29001E-05ADIRF+FALSE
chr568850966GT0.00134OCLN+FALSEAluSx4SINE,Alu
chr439549797TC0.00196UGDH-AS1,SMIM14+,-FALSEAluSpSINE,Alu
chr110520178TC2.78615E-06.FALSEAluSxSINE,Alu
chr1118066459AG0.00496MAN1A2+FALSE
chr1269158881AG0.00219SLC35E3+TRUEAluSpSINE,Alu
chr799636950AG0.00927ZKSCAN1+FALSEAluSx1SINE,Alu
chr1144931330CT0.00479NBPF20,PDE4DIP+,-FALSE
chr1560678712GA0.00801ANXA2-FALSE
chr140537923GA6.08919E-05CAP1+FALSE(A)nSINE,Alu
chr5149823799AT0.00672RPS14-FALSE
chr111347150CA0.00016UBIAD1+FALSE
chr1159887904AT8.82173E-05TAGLN2-FALSE
chr11668168GT1.67311E-07SLC35E2-FALSEAluSzSINE,Alu
chr1431916783TC3.40362E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr145241211CT0.00947.FALSE
chr159122059GA0.00476MYSM1-FALSE
chr1205737659CT0.00024RAB29-FALSEAluSq2SINE,Alu
chr1256510559AG0.00137RPL41+FALSE
chr315114421TC0.00353RBSN-TRUEAluYSINE,Alu
chr127074517CT0.00369PHB2-FALSE
chr1590820104AG4.84304E-05.FALSEAluYSINE,Alu
chr442003671AG0.00535SLC30A9+FALSE
chr348632596AG0.00666.FALSE
chr42940371TC0.00905NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr145452227GC0.00126EIF2B3-FALSE
chr223918891CT1.03047E-06KLHL29+FALSE
chr837613073AC0.00394ERLIN2+FALSE(CCCCCAC)nSINE,Alu
chr1145688664AT0.00298NBPF20,NBPF10,RNF115+FALSE
chr122854931CA7.08508E-09ZBTB40+FALSEA-richSINE,Alu
chr286252198TC0.00076POLR1A-TRUEAluSq2SINE,Alu
chr556177846GC0.00952MAP3K1+FALSE
chr1226809316GA0.00150ITPR2-FALSE
chr1120163248GA0.00711ZNF697-FALSE
chr323958355CT0.00997NKIRAS1,RPL15+,-FALSE
chr119565338CT0.00631LOC101927895,EMC1+,-FALSE
chr117998CT0.00194WASH7P-FALSE
chr110517486TC0.00626.FALSEAluSx1SINE,Alu
chr132799508AC8.53764E-05MARCKSL1-FALSE
chr1203766872GA1.42518E-06ZC3H11A,ZBED6+FALSE
chr1144596317CT0.00020NBPF20+FALSEAluJbSINE,Alu
chr1206635246AT0.00283SRGAP2+FALSE(AC)nSINE,Alu
chr110517352TC0.00064.FALSEAluJrSINE,Alu
chr146077268AG0.00311NASP+TRUEAluSc8SINE,Alu
chr1939433139TG0.00235FBXO17-FALSEAluJbSINE,Alu
chr642857111AG0.00021RPL7L1+FALSEAluSpSINE,Alu
chr1210025751GA4.42687E-05DIEXF+FALSETigger4aSINE,Alu
chr146078630AG0.00131NASP+FALSE
chr119586458AG1.61978E-09MRTO4+TRUEAluSzSINE,Alu
chr136529575AG2.40551E-05.FALSEAluJrSINE,Alu
chr139549983GA0.00896MACF1+FALSE
chr110517691TC0.00558.FALSEAluSx1SINE,Alu
chr417629934TC0.00178.FALSEMER90SINE,Alu
chr624719404CA0.00024.FALSE
chr110518797TC0.00421.FALSEAluSx1SINE,Alu
chr1200375837TG0.00429ZNF281-FALSE(T)nSINE,Alu
chr19161011TC7.97270E-05.FALSEAluJbSINE,Alu
chr1151668295AC0.00576SNX27+FALSE
chr16282324TC0.00186ICMT-TRUEAluSzSINE,Alu
chr340503772TA0.00153RPL14+FALSE
chr1112003958TA0.00557ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr152817399TC0.00346CC2D1B-TRUEAluSg4SINE,Alu
chr1154128839GT0.00534TPM3-FALSE
chr7100739267GA0.00654.FALSEAluSxSINE,Alu
chr2197021372TA0.00285STK17B-FALSE
chr122855441CT0.00884ZBTB40+FALSE
chr4109551185GA0.00344RPL34+FALSE
chr111783009AG7.55078E-05.FALSEAluSxSINE,Alu
chr116891340TA0.00022NBPF1-FALSE
chr126449882AG0.00783PDIK1L+FALSE
chr314986104TC0.00621FGD5-AS1-TRUEFLAM_CSINE,Alu
chr371005566CT0.00209FOXP1-FALSE(T)nSINE,Alu
chr113716835CT0.00828NUP98-FALSE
chr115993013GA1.61862E-10.FALSE
chr132508397TC0.00166KHDRBS1+FALSE
chr744918804TC0.00015PURB-TRUEAluSgSINE,Alu
chr116957414CT0.00708.FALSE
chr275118737CT0.00154HK2+FALSE
chr1757279257AG0.00077PRR11+TRUEAluSq2SINE,Alu
chr116096934CT0.00336FBLIM1+FALSE
chr237333924TC0.00298EIF2AK2-FALSEAluSzSINE,Alu
chr144818525TC0.00235ERI3-FALSE
chr122186113TG0.00083HSPG2-FALSE
chr825317824AT0.00017CDCA2+FALSE
chr1200827638AG0.00665CAMSAP2+FALSE
chr647200348TC0.00274TNFRSF21-FALSE
chr2201749994TC0.00496PPIL3-TRUEAluSxSINE,Alu
chr236704033TA0.00012CRIM1+FALSE
chr448854139TC0.00133OCIAD1+FALSEL2cSINE,Alu
chr2174773510TA0.00775SP3-FALSEA-richSINE,Alu
chr323962339TA0.00925RPL15+FALSE
chr128826150AG0.00152PHACTR4+TRUEAluJbSINE,Alu
chr21652354GA0.00000PXDN-FALSE
chr5149829073AG0.00866RPS14-FALSE
chr1590819409AG5.75884E-05.FALSEAluSxSINE,Alu
chr116932368TA0.00336NBPF1-FALSEMLT1F-intSINE,Alu
chr1163394016TC0.00106ATL3-FALSE
chr112628188TC6.05765E-06DHRS3-FALSE
chr9128729384GC0.00059PBX3+FALSE
chr143629979GT0.00470EBNA1BP2-FALSE
chr1154987526CT0.00218ZBTB7B+FALSE
chr153712569CA0.00061LRP8-FALSE(CA)nSINE,Alu
chr933046889TA0.00932SMU1-FALSEAluSzSINE,Alu
chr1118502685TA0.00333WDR3,SPAG17+,-FALSE
chr116529016CT0.00024ARHGEF19-FALSE
chr838829416AG0.00695PLEKHA2+TRUEAluYcSINE,Alu
chr699319240TA0.00842.FALSECheshireSINE,Alu
chr119201928CT0.00149ALDH4A1-FALSE
chr110043840GT6.08980E-05NMNAT1+FALSE
chr13546137AC0.00778TPRG1L+FALSEAluSzSINE,Alu
chr4185309405AG0.00035IRF2-FALSE
chr136068295TC0.00058PSMB2-TRUEAluScSINE,Alu
chr3195411267AG1.93837E-05SDHAP2+FALSE
chr119653870TC0.00477PQLC2+FALSE
chr112638964TC0.00884DHRS3-FALSE
chr3196082911TC0.00250UBXN7-FALSE
chr1110949720CT0.00666LAMTOR5-FALSEL1ME4bSINE,Alu
chr245640374CA0.00578SRBD1-FALSE
chr175288081CT0.00518RABEP1+FALSE
chr1911257634TC0.00237SPC24-TRUEAluSpSINE,Alu
chr5125961816AG0.00013PHAX+TRUEFLAM_CSINE,Alu
chr1224621934GC0.00245WDR26-FALSE(GGA)nSINE,Alu
chr1982994TC0.00432AGRN+FALSE
chr457801196GA0.00485REST+FALSE
chr5149363214AG0.00040SLC26A2+TRUEAluJrSINE,Alu
chr1117644949CG0.00862TTF2+FALSE
chr136068231TC0.00582PSMB2-TRUEAluScSINE,Alu
chr565452100GT0.00600SREK1+FALSE(TTTTTG)nSINE,Alu
chr1921304019AG0.00111ZNF714+TRUEAluYSINE,Alu
chr310192747AG0.00065VHL+TRUEAluSx1SINE,Alu
chr3124948047CG0.00285ZNF148-FALSE
chr13545194CG0.00254TPRG1L+FALSE
chr1254634283TC0.00047CBX5-TRUEAluJrSINE,Alu
chr5149763305AG0.00640TCOF1+FALSE
chr4128758152AG0.00198.FALSEAluSxSINE,Alu
chr1114940216TG0.00074TRIM33-FALSE(T)nSINE,Alu
chr917835AG0.00012WASH1-FALSE
chr145671429GA0.00054ZSWIM5-FALSE
chr345960561TA9.94810E-07FYCO1-FALSE
chr11662547TC0.00556SLC35E2-TRUEAluYSINE,Alu
chr373024350CA0.00109GXYLT2+FALSE
chr1320224387AG0.00959MPHOSPH8+FALSE
chr116912099GC0.00450NBPF1-FALSE
chr136067752TC9.44020E-05PSMB2-TRUEAluSzSINE,Alu
chr1151955393TC7.77942E-05S100A10-FALSE
chr1591044381CA0.00440IQGAP1+FALSE
chr2217366195CA0.00929.FALSE
chr1475202512AG0.00053FCF1+TRUEAluScSINE,Alu
chr1113247898GA0.00077RHOC-FALSE
chr510265488AG0.00120CCT5+FALSE
chr1206579798TC0.00883SRGAP2+FALSE
chr271298486TC0.00408NAGK+FALSE
chr1145512014AG0.00370NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr147746678GC0.00374STIL-FALSE
chr145975266AG0.00188MMACHC+TRUEAluSg7SINE,Alu
chr3194309210GA0.00317TMEM44-AS1,TMEM44+,-FALSE
chr132374019GA0.00297PTP4A2-FALSE
chr167874859TC0.00209SERBP1-TRUEAluSxSINE,Alu
chr1228520973CG0.00875OBSCN+FALSE
chr3179115697TC3.71610E-05GNB4-TRUEAluSg7SINE,Alu
chr3195243006CA0.00982PPP1R2-FALSE
chr11431165CT0.00392ATAD3B+FALSE
chr1168213516AG0.00233.FALSEAluSx1SINE,Alu
chr1151092875AG0.00154GABPB2+TRUEAluSpSINE,Alu
chr315113042CT4.09809E-05RBSN-FALSE
chr56633042CT0.00377NSUN2-FALSE
chr110520764TC0.00542DFFA-TRUEAluSc8SINE,Alu
chr1148252049AC0.00666NBPF8,NBPF14,NBPF9-FALSE
chr155207983TA0.00018MROH7-TTC4,TTC4+FALSE
chr1204095426CT0.00481SOX13+FALSE
chr9137330716AC0.00058RXRA+FALSE
chr154692334TC5.22151E-05SSBP3-FALSE(T)nSINE,Alu
chr19642827GA0.00985SLC25A33+FALSE
chr1988503AT0.00141AGRN+FALSE
chr1227922767GT0.00202SNAP47,JMJD4+,-FALSE
chr1563363384CA0.00161TPM1+FALSE
chr1145281408CT0.00220NBPF20,NOTCH2NL+FALSE
chr1218617066AT0.00211TGFB2-OT1,TGFB2+FALSE
chr247387305GT0.00322CALM2-FALSE
chr199672943TC1.63385E-06.FALSEAluSx3SINE,Alu
chr1247319707CT3.10675E-05ZNF124-FALSE
chr237330172TG0.00972.FALSE
chr457326875AG1.03861E-05PAICS+TRUEAluSx1SINE,Alu
chr1100548780AT0.00791MFSD14A+FALSE
chr3197612267AG0.00341.FALSEAluSpSINE,Alu
chr8143763618CG0.00421PSCA+FALSE
chr287002706GA0.00178RMND5A+FALSE
chr16283434TC0.00285ICMT-TRUEAluSx3SINE,Alu
chr1474526154TC0.00030BBOF1,ALDH6A1+,-FALSEAluSpSINE,Alu
chr989626918AG0.00048LOC440173-FALSE
chr2174090336AC0.00331ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr5125961426AG0.00434PHAX+TRUEAluSz6SINE,Alu
chr128835934AG0.00193SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr138002251GC0.00624SNIP1-FALSE
chr1179044181AG0.00790FAM20B+TRUEAluSxSINE,Alu
chr19642828TA0.00148SLC25A33+FALSE
chr126608017TA3.67009E-06.FALSE
chr5138618619AG0.00513SNHG4,MATR3+TRUEAluSxSINE,Alu
chr299772827AG0.00377LIPT1+TRUEAluSx1SINE,Alu
chr110520378TC0.00743.FALSEAluSx1SINE,Alu
chr119585207GA0.00672MRTO4+FALSE
chr169204015CT0.00325C16orf72+FALSE
chr13545186TG0.00314TPRG1L+FALSE
chr1145513016AG0.00069NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr195660019GT0.00052TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr1742876808TC0.00147GJC1-TRUEAluSz6SINE,Alu
chr1224575827TC0.00214WDR26-FALSE
chr133149443AG0.00327SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1153587308CT0.00077S100A14-FALSE
chr5170832637CT0.00071NPM1+FALSE
chr1186641127AT0.00546PTGS2-FALSE
chrX2824933TC0.00066ARSD-TRUEAluSx1SINE,Alu
chr116576295GA0.00231FBXO42-FALSEA-richSINE,Alu
chr642854739AC0.00671RPL7L1+FALSEAluScSINE,Alu
chr178201745GT0.00140USP33-FALSE
chr116934178CT0.00382NBPF1-FALSE
chr232535692AG0.00236.FALSEAluJbSINE,Alu
chr128825760AG0.00802PHACTR4+TRUEAluSpSINE,Alu
chr315113893TC0.00042RBSN-TRUEAluSz6SINE,Alu
chr146828700AG0.00805NSUN4+FALSE
chr254887287CT7.50624E-05SPTBN1+FALSE
chr13730332TC6.29937E-05CEP104-TRUEAluSx3SINE,Alu
chr817087341CA0.00197CNOT7-FALSE
chr119543352TC0.00087LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr237331119TC0.00122.FALSEAluSx1SINE,Alu
chr39829171GA0.00730TADA3-FALSE
chr1117530213GT0.00256PTGFRN+FALSE
chr1114443458AG0.00320AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr340577755AG0.00044ZNF621+TRUEAluSzSINE,Alu
chr2198416735TG0.00257HSPE1-MOB4,MOB4+FALSE
chr110519982TC0.00129.FALSEAluJrSINE,Alu
chr315112495TC0.00030RBSN-TRUEAluSq2SINE,Alu
chr1145500917GC0.00930NBPF20,NBPF10,LIX1L+FALSE
chr344791398TC0.00204KIAA1143-TRUEAluJrSINE,Alu
chr76500726AT0.00560KDELR2-FALSE
chr140214148AG0.00426PPIE+TRUEAluSq2SINE,Alu
chr187573348CA0.00879HS2ST1+FALSE
chr2054963756TC0.00476AURKA-TRUEAluSq10SINE,Alu
chr136068231TC0.00022PSMB2-TRUEAluScSINE,Alu

Differential Expression Gene Analysis