Dataset Overview
RBP
EIF2S2
Knock-Method
shRNA
RBP Family
eIF-5_eIF-2B
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR110HAA
Platform
HiSeq
Pubmed ID
32252787
EIF2S2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of EIF2S2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
32.44
33.09
-0.10647
0.04174
0.07062
A2M
2405.22
2418.71
-0.11742
0.01008
0.02006
A4GALT
0.67
0.95
0.54274
0.03122
0.05457
AACS
11.23
8.15
-0.37466
3.30072E-08
1.76514E-07
AADAT
6.54
10.07
0.51835
9.52749E-08
4.73376E-07
AAK1
3.76
6.64
0.98664
1.00771E-30
4.20479E-29
AAMDC
12.7
8.52
-0.41776
0.00699
0.01453
AAMP
92.31
88.69
-0.19024
0.00108
0.00268
AARS
42.28
84.44
1.09954
2.42988E-96
1.09780E-93
AASDH
4.79
3.04
-0.54188
2.71158E-09
1.69177E-08
Showing 1 to 10 of 7,922 entries
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Function Analysis of Target Genes of EIF2S2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC084018.1
122240536_122240690_122239612_122239714_122240784_122241390
0.00947
-0.315
DataSet_01_418
View details
AC084018.1
122240536_122240712_122239612_122239714_122240784_122240851
0.00515
-0.329
DataSet_01_418
View details
ACBD4
43213866_43213987_43213474_43213599_43214058_43214143
0.00995
-0.2
DataSet_01_418
View details
ADD1
2928365_2928402_2927740_2927839_2929897_2931054
0.00493
0.053
DataSet_01_418
View details
ADD1
2928368_2928402_2927740_2927839_2929897_2931789
0.00432
0.058
DataSet_01_418
View details
AFP
74320952_74321007_74319481_74319614_74321347_74321891
0.00168
-0.007
DataSet_01_418
View details
AHSG
186337645_186337696_186336300_186336426_186338374_186339107
0.00000
-0.08
DataSet_01_418
View details
AHSG
186336324_186336426_186334972_186335139_186338374_186339089
0.00000
-0.016
DataSet_01_418
View details
AHSG
186337645_186337729_186336300_186336426_186338374_186339089
0.00000
-0.015
DataSet_01_418
View details
AHSG
186336079_186336177_186334975_186335139_186336324_186336426
0.00560
-0.006
DataSet_01_418
View details
Showing 1 to 10 of 121 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAT1
108002633_108002681_108004546_108004664_107992293_107992405
0.00079
0.118
DataSet_01_418
View details
AFP
74306318_74306530_74313178_74313393_74303890_74304023
0.00000
0.115
DataSet_01_418
View details
AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00000
-0.17
DataSet_01_418
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00000
-0.169
DataSet_01_418
View details
AHSG
186336079_186336280_186336358_186336426_186334975_186335139
0.00000
-0.172
DataSet_01_418
View details
AHSG
186336358_186336426_186337645_186337729_186334975_186335139
0.00000
0.018
DataSet_01_418
View details
AHSG
186336324_186336426_186337645_186337729_186334231_186334316
0.00002
0.013
DataSet_01_418
View details
AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00003
-0.012
DataSet_01_418
View details
AHSG
186336285_186336426_186337645_186337729_186334975_186335139
0.00015
0.01
DataSet_01_418
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00017
-0.007
DataSet_01_418
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Showing 1 to 10 of 94 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ENPP3
131995301_131995502_131995301_131995421_131996219_131996329
0.00968
-0.062
DataSet_01_418
View details
F5
169489757_169489902_169489764_169489902_169487649_169487801
0.00738
0.026
DataSet_01_418
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FAM213A
82182172_82182345_82182172_82182264_82185621_82185762
0.00623
0.263
DataSet_01_418
View details
GNAS
57464214_57464408_57464214_57464387_57470666_57470739
0.00602
-0.115
DataSet_01_418
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GRB7
37902361_37902553_37902361_37902455_37903003_37903241
0.00585
0.062
DataSet_01_418
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HSD17B7
162767591_162768725_162767591_162767706_162769532_162769727
0.00185
0.093
DataSet_01_418
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MAP4K4
102503549_102503723_102503549_102503699_102504239_102504399
0.00001
0.107
DataSet_01_418
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RCC1
28832501_28832612_28832501_28832596_28834639_28834672
0.00806
0.022
DataSet_01_418
View details
RP11-216L13.19
139699808_139699968_139699808_139699909_139700529_139701124
0.00378
-0.025
DataSet_01_418
View details
TXLNG2P
21729235_21729456_21729235_21729290_21749095_21749393
0.00420
-0.2
DataSet_01_418
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Showing 1 to 10 of 11 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AKAP8L
15509440_15509577_15509440_15509514_15510112_15510221
0.00237
-0.175
DataSet_01_418
View details
APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00037
-0.017
DataSet_01_418
View details
APOA2
161193139_161193247_161193139_161193215_161193384_161193418
0.00445
-0.028
DataSet_01_418
View details
ASGR2
7017492_7017717_7017492_7017706_7017933_7018130
0.00538
-0.044
DataSet_01_418
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ASPSCR1
79970031_79970159_79970106_79970159_79969418_79969481
0.00589
-0.028
DataSet_01_418
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CLINT1
157216370_157216575_157216370_157216521_157218710_157219003
0.00460
-0.147
DataSet_01_418
View details
DHRS2
24110874_24112428_24112360_24112428_24109002_24109104
0.00676
-0.033
DataSet_01_418
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DLG5
79614020_79614128_79614020_79614116_79616487_79616650
0.00768
0.167
DataSet_01_418
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EFNA1
155105978_155106256_155106205_155106256_155103814_155104110
0.00776
-0.058
DataSet_01_418
View details
FN1
216236631_216237098_216236631_216236738_216238044_216238134
0.00000
-0.011
DataSet_01_418
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Showing 1 to 10 of 26 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ARPC3
110873914_110874488_110873914_110874009_110874361_110874488
0.00867
-0.01
DataSet_01_418
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ATXN2L
28847253_28848558_28847253_28847806_28848048_28848558
0.00954
-0.107
DataSet_01_418
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CLK1
201724402_201726189_201724402_201724469_201725960_201726189
0.00119
0.22
DataSet_01_418
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DDX5
62498279_62498667_62498279_62498341_62498556_62498667
0.00036
0.065
DataSet_01_418
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DDX5
62499212_62499418_62499212_62499216_62499305_62499418
0.00607
0.014
DataSet_01_418
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FAM133B
92206968_92207496_92206968_92207031_92207463_92207496
0.00931
0.068
DataSet_01_418
View details
FN1
216243852_216247048_216243852_216244040_216246934_216247048
0.00010
-0.013
DataSet_01_418
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FTH1
61734783_61735103_61734783_61734843_61734929_61735103
0.00877
0.043
DataSet_01_418
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HNRNPC
21677294_21679725_21677294_21679465_21679564_21679725
0.00031
0.019
DataSet_01_418
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HPN
35532625_35533426_35532625_35532776_35533356_35533426
0.00596
0.111
DataSet_01_418
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Showing 1 to 10 of 14 entries
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
16912014
A
C
0.00704
NBPF1
-
FALSE
chr1
6473294
A
G
0.00013
.
FALSE
Arthur1C
SINE,Alu
chr1
36529575
A
G
2.40551E-05
.
FALSE
AluJr
SINE,Alu
chr1
115299504
G
T
0.00067
CSDE1
-
FALSE
chr1
11901592
T
C
0.00076
CLCN6,NPPA-AS1
+
FALSE
chr1
46269545
G
A
0.00378
MAST2
+
FALSE
chr1
78142911
T
C
0.00925
ZZZ3
-
TRUE
AluSx
SINE,Alu
chr1
26755209
A
G
0.00745
LIN28A
+
FALSE
AluSx1
SINE,Alu
chr1
36068369
T
C
0.00207
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
32373854
A
T
0.00096
PTP4A2
-
FALSE
Showing 1 to 10 of 374 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression