Dataset Overview
RBPEWSR1
Knock-MethodshRNA
RBP Familyzf-RanBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR831YGP
PlatformHiSeq
Pubmed ID32252787

EWSR1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EWSR1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EWSR1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr119542456TC0.00193LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr122418284GT0.00024CDC42+FALSE(T)nSINE,Alu
chr4165998078TC0.00567TMEM192-TRUEAluSxSINE,Alu
chr425279508GA3.42130E-11PI4K2B+FALSE
chr1949468569GT0.00266FTL+FALSE
chr74809089AG0.00552FOXK1+TRUEAluSx1SINE,Alu
chr1145513090AG0.00017NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr147767914GA0.00061STIL-FALSE
chr11650797AG3.70820E-05CDK11B,CDK11A-FALSE
chr1298943103AG3.95351E-06TMPO+TRUEAluSzSINE,Alu
chr138423182GC0.00664SF3A3-FALSEAluJoSINE,Alu
chr154691922TA0.00067SSBP3-FALSE
chr1206635244TA0.00195SRGAP2+FALSE
chr12125511942AG0.00596THRIL-FALSEAluSx1SINE,Alu
chr2140567665GA0.00786BRWD1-FALSE
chr145975286AG0.00200MMACHC+TRUEAluSg7SINE,Alu
chr11650801TC0.00827CDK11B,CDK11A-FALSE
chr1117531621AG0.00577PTGFRN+FALSE
chr116890421GA0.00024NBPF1-FALSE
chr119578192GA0.00246MRTO4+FALSE
chr125688276AG0.00015TMEM50A+FALSE
chr2128601583TC0.00550.FALSEAluJrSINE,Alu
chr143167907TC0.00072YBX1+FALSE
chr119934793GA0.00376MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1541590999AG0.00049OIP5-AS1+TRUEAluSx1SINE,Alu
chr2208620143AG0.00605CCNYL1+TRUEEutTc1-N1SINE,Alu
chr189237556CT0.00840PKN2+FALSE
chr110042955AG0.00430NMNAT1+TRUEAluScSINE,Alu
chr1950412217CG0.00017IL4I1,NUP62-FALSE(GGT)nSINE,Alu
chr116932428CG0.00620NBPF1-FALSEL1MC2SINE,Alu
chr1919792288AG0.00379ZNF101+TRUEAluJbSINE,Alu
chr119543973TC0.00236LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr145975345AG0.00129MMACHC+TRUEAluSg7SINE,Alu
chr2187544230TA0.00930ITGAV+FALSE
chr1148343689AG0.00517NBPF8,NBPF14,NBPF9-FALSE
chr1115275398TG0.00474CSDE1-FALSE
chr439550085TC3.55103E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr1100489835AG0.00230SLC35A3+TRUEAluSgSINE,Alu
chr1675479470TC3.73920E-07TMEM170A-TRUEAluJbSINE,Alu
chr337031951GA0.00914EPM2AIP1-FALSE(A)nSINE,Alu
chr2234386134AG0.00196USP40-FALSE
chr119543457TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr119586501AG5.42567E-10MRTO4+TRUEAluSzSINE,Alu
chr1541593268AG0.00084.FALSEAluSz6SINE,Alu
chr722765456GT5.19964E-05LOC541472-FALSE
chr1177976440CT0.00148LOC730102-FALSE
chr261277463AG0.00826PEX13+TRUEAluSxSINE,Alu
chr3156258389TC0.00179SSR3-TRUEAluYk3SINE,Alu
chr439289308GC0.00509RFC1-FALSE
chr2152132130AG0.00071NMI-FALSE
chr1145283980CT0.00113NBPF20,NOTCH2NL+FALSE
chr3129152089GA0.00154MBD4-FALSE
chr42940364TC0.00329NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr237331525TC0.00020.FALSEAluJbSINE,Alu
chr581571876AT0.00092RPS23-FALSE
chr4183721749GA0.00324TENM3+FALSE
chr136789546AG0.00562EVA1B-FALSEMIRbSINE,Alu
chr1172411496AG0.00361C1orf105,PIGC+,-FALSE
chr1109180686CT1.31584E-05FAM102B+FALSE
chr2203744240TC0.00595.FALSEAluSxSINE,Alu
chr5204215AG0.00872.FALSEMER68SINE,Alu
chr5176883676AT0.00456DBN1-FALSE(A)nSINE,Alu
chr1149818472TC0.00131.FALSEMLT1DSINE,Alu
chr138326704TC0.00328INPP5B-TRUEAluJrSINE,Alu
chr1244181367GA0.00608IRAK4+FALSEMLT1E1ASINE,Alu
chr744841236GA0.00819PPIA+FALSE
chr110520669TC0.00963DFFA-FALSEAluSc8SINE,Alu
chr19162224TC0.00523.FALSEAluSxSINE,Alu
chr1193054154GA0.00757TROVE2+FALSE
chr128826085AG0.00212PHACTR4+TRUEAluJbSINE,Alu
chr1145442111CA0.00090NBPF20,NBPF10,TXNIP+FALSE
chr1109465167TA0.00233GPSM2+FALSE
chr13546132GA0.00113TPRG1L+FALSEAluSzSINE,Alu
chr153291408AG0.00021ZYG11B+TRUEAluJrSINE,Alu
chr119934758CG1.75422E-05MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr117287301AG0.00104CROCC+FALSE
chr128826150AG0.00152PHACTR4+TRUEAluJbSINE,Alu
chr1179829425TC1.55944E-05TOR1AIP2-TRUEAluJrSINE,Alu
chr310356760GA0.00951SEC13-FALSEMIRbSINE,Alu
chr1144614842CG0.00015NBPF20+FALSE
chr11647814TC7.10450E-06CDK11B,CDK11A-FALSE
chr3141164940CA0.00194ZBTB38+FALSE
chr327763674TG0.00617EOMES-FALSE
chr217897488TC0.00430SMC6-FALSE
chr237331855CT0.00965.FALSEL1MC4SINE,Alu
chr1028971536AT0.00815BAMBI+FALSE
chr132373854AT0.00096PTP4A2-FALSE
chr1075008846TC0.00135DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr386991598GT0.00179VGLL3-FALSE
chr11597403CT0.00912CDK11B,SLC35E2B-FALSE
chr6143832707GA0.00418FUCA2-FALSE(GCA)nSINE,Alu
chr3160213318TG0.00215KPNA4-FALSE
chr422404391GA0.00338ADGRA3-FALSE
chr1155032752AG0.00347LOC100505666,ADAM15+,-FALSE
chr1165877671TC0.00376UCK2+FALSE(T)nSINE,Alu
chr1256215102TA0.00405DNAJC14-FALSE
chr7158590740AT0.00211ESYT2-FALSE
chr342592902TC5.80731E-05SEC22C-FALSEAluJrSINE,Alu
chr1179832838AG0.00018TOR1AIP2-FALSEMLT1LSINE,Alu
chr488061645TA0.00049AFF1+FALSE(TATAT)nSINE,Alu
chr1180082702GC0.00019CEP350+FALSE
chr6150046603TC0.00763NUP43-TRUEAluSq2SINE,Alu
chr1168218543AG0.00547.FALSEAluSzSINE,Alu
chr42940371TC0.00905NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr110044366AG0.00958NMNAT1+TRUEAluSx1SINE,Alu
chr136534736AG0.00016.FALSEAluJoSINE,Alu
chr145975673AG0.00242MMACHC+TRUEAluSx4SINE,Alu
chr799649179AG0.00360ZSCAN21+TRUEAluYSINE,Alu
chr127108245TC0.00265ARID1A+FALSE
chr1544055281TC0.00580PDIA3+FALSE
chr2113334414AG0.00281POLR1B+TRUEAluSzSINE,Alu
chr273460299GC0.00180PRADC1-FALSE(CGGCGC)nSINE,Alu
chr187328433TC3.09926E-06SEP15-FALSE
chr163207363CT0.00104.FALSE
chr11447756GC0.00354ATAD3A+FALSE
chr13545198TC0.00013TPRG1L+FALSE
chr193301947CT0.00039FAM69A,RPL5+,-FALSE
chr153289547AG0.00505ZYG11B+TRUEAluSzSINE,Alu
chr1761502459TA0.00161TANC2+FALSE
chr116945570AG0.00251CROCCP2-FALSE
chr729962666TA0.00077SCRN1-FALSE
chr120976032TC9.95086E-05PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr647592330TA0.00830CD2AP+FALSE
chr132669918GA0.00344CCDC28B+FALSE
chr2183642878GA0.00373DNAJC10+FALSE
chr131532312CT0.00215PUM1-FALSE
chr1160990876CA1.09997E-06F11R-FALSE
chr193828011GT0.00464DR1+FALSE
chr642855200AG2.13337E-05RPL7L1+TRUEAluSpSINE,Alu
chr7138764145TC0.00399ZC3HAV1-FALSE
chr310192694AG0.00277VHL+TRUEAluSx1SINE,Alu
chr1298942820AG0.00568TMPO+TRUEAluScSINE,Alu
chr139470978TA0.00378AKIRIN1+FALSEAluSx1SINE,Alu
chr1749041692TC2.35976E-05SPAG9-TRUEAluSxSINE,Alu
chr116889624TC0.00614NBPF1-TRUE
chr5134086670CA0.00585CAMLG+FALSE
chrX77083007TC0.00371MAGT1-TRUEAluSgSINE,Alu
chr16279957AG0.00814RNF207+TRUEAluSpSINE,Alu
chr399516962CA2.05391E-14MIR548G-FALSE
chr1207247475CA0.00680PFKFB2+FALSEMER5BSINE,Alu
chr1212114662AG0.00858INTS7-FALSE
chr16583538TC0.00455NOL9-TRUEAluSqSINE,Alu
chr466439443TC0.00593EPHA5-FALSE
chr110520505TC0.00011.FALSEAluSx1SINE,Alu
chr5145493224AT0.00251LARS-FALSE
chr133150643GA0.00606SYNC,RBBP4+,-FALSEAluJoSINE,Alu
chr5150578574AG0.00447CCDC69-FALSE
chr3101405564GA0.00354.FALSE
chr128564195TC0.00113ATPIF1+FALSE
chr568850922GC0.00323OCLN+FALSEAluSx4SINE,Alu
chr825272364CG0.00693DOCK5+FALSE
chr1145688973AG8.24717E-05NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr128826114AG0.00264PHACTR4+TRUEAluJbSINE,Alu
chr19162932AT0.00635.FALSE
chr1154554950GT0.00599ADAR-FALSE
chr1100489996AG0.00069SLC35A3+TRUEAluSgSINE,Alu
chr193467756CT0.00485NFIC+FALSE(TA)nSINE,Alu
chr1542861705AG0.00518HAUS2+TRUEAluJbSINE,Alu
chr340577755AG0.00044ZNF621+TRUEAluSzSINE,Alu
chr791742141TA0.00620CYP51A1-FALSEAluSx3SINE,Alu
chr9132266648AG0.00230LINC00963+TRUEAluSxSINE,Alu
chr155619569CT0.00477USP24-FALSE
chr140219065CT0.00232PPIE+FALSE
chrM8859GA0.00929.FALSE
chr3107526182TC7.17610E-07BBX+FALSE
chr135816903CT0.00174ZMYM4+FALSE
chr11246979GT0.00168PUSL1,CPSF3L+,-FALSE
chr110517276TC0.00039.FALSEAluJrSINE,Alu
chr1911256702TC6.98885E-06SPC24-TRUEAluJr4SINE,Alu
chr1269159400GA0.00173SLC35E3+FALSE(AT)nSINE,Alu
chr3124488267GA3.46260E-06ITGB5-FALSE
chr7102004748TC0.00050LOC100289561,LOC100630923+FALSE
chr220818330TC0.00228HS1BP3-TRUE
chr1939433139TG0.00235FBXO17-FALSEAluJbSINE,Alu
chr5134061334AG0.00721SEC24A+FALSE
chr934088029CT0.00501DCAF12-FALSE
chr237328012TC6.47624E-05.FALSE
chr2114220055TC9.23000E-05CBWD2+FALSE
chr126755536AG0.00515LIN28A+TRUEAluScSINE,Alu
chr16695423TG9.25675E-05THAP3,DNAJC11+,-FALSE
chr119653870TC0.00477PQLC2+FALSE
chr1740723650AT0.00250MLX+FALSE
chr483406548AT0.00020TMEM150C-FALSE
chr2239069181TC0.00346CBY1+FALSE
chr1142688511TC0.00089.FALSE
chr16314743CT0.00615GPR153-FALSE
chr1918475303AG0.00757PGPEP1+TRUEAluSx1SINE,Alu
chr193828523TA0.00155.FALSE
chr2102508658TA0.00275MAP4K4+FALSE
chr247085954CT0.00805LINC01119+FALSE
chr1953914448AG0.00583ZNF765+TRUEAluSxSINE,Alu
chr5162902516TC0.00226HMMR+FALSE
chr1254634283TC0.00047CBX5-TRUEAluJrSINE,Alu
chr1145512014AG0.00370NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr119199221CT0.00676ALDH4A1-FALSE
chr1450792961GA0.00547.FALSEAluSxSINE,Alu
chr199673275TC0.00081.FALSETigger1SINE,Alu
chr1114940216TG0.00148TRIM33-FALSE(T)nSINE,Alu
chr110520072TC0.00115.FALSEAluSxSINE,Alu
chr126604691GC0.00043CEP85+FALSE
chr119810692AC0.00069CAPZB-FALSE
chr116893841CT0.00272NBPF1-FALSE
chr1168523082TC0.00019CPT1A-TRUEAluYSINE,Alu
chr41305799CT0.00271MAEA+FALSE
chr187811103TG0.00028LMO4+FALSE
chr147142539TA0.00066EFCAB14-AS1,EFCAB14+,-FALSE
chr127202844TC0.00076.FALSEAluSq2SINE,Alu
chr5140798639GC3.89156E-05PCDHGA1,PCDHGA2,PCDHGA3,PCDHGB1,PCDHGA4,PCDHGB2,PCDHGA5,PCDHGB3,PCDHGA6,PCDHGA7,PCDHGB4,PCDHGA8,PCDHGB5,PCDHGA9,PCDHGB6,PCDHGA10,PCDHGB7+FALSE
chr3181430141GC0.00086SOX2-OT,SOX2+FALSE

Differential Expression Gene Analysis