Dataset Overview
RBPCNOT7
Knock-MethodshRNA
RBP FamilyCAF1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR274KWA
PlatformHiSeq
Pubmed ID32252787

CNOT7 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of CNOT7
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of CNOT7


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1167759281TC0.00923MPZL1+FALSE
chr743679092GC1.19724E-06COA1-FALSE
chr466439707TC0.00148EPHA5-FALSE
chr152306075TC0.00135NRDC-FALSE(TCA)nSINE,Alu
chr11309464CT3.88389E-12AURKAIP1-FALSE
chr140214261AG0.00879PPIE+TRUEAluSq2SINE,Alu
chr2127826533AG0.00942BIN1-FALSE
chr111119935GT2.46542E-05SRM-FALSE
chr1244182706AG0.00788IRAK4+FALSEMSTB-intSINE,Alu
chr3156259331TC0.00088SSR3-TRUEAluSq2SINE,Alu
chr744917316TC0.00564PURB-FALSEAluSzSINE,Alu
chr626095468AG0.00980HFE+TRUEAluYSINE,Alu
chr1176835290CT0.00011CAPN5+FALSE
chr111181327CT0.00573MTOR-FALSE
chr2204162597AG0.00296CYP20A1+TRUEAluSxSINE,Alu
chr744842429TG0.00384PPIA+FALSE
chr579923430TC0.00817DHFR-TRUEAluJrSINE,Alu
chr124995941AG0.00382SRRM1+FALSE
chr133148623AG0.00221SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1224380757AG0.00618DEGS1+FALSEAluSxSINE,Alu
chr3179117128TC0.00239GNB4-TRUEAluSzSINE,Alu
chr764023371TC0.00824ZNF680-FALSE
chr1144815953AG0.00348NBPF20,NBPF9+FALSE
chr261416411TG0.00146USP34-FALSEAluSc8SINE,Alu
chr1326499AG0.00583.FALSE
chr1570178GA0.00787.FALSE
chr413601337GA7.28365E-09BOD1L1-FALSE
chr1104097685CT0.00028RNPC3,AMY2B+FALSE
chr72274221TC0.00579MRM2-TRUEAluJrSINE,Alu
chr315113842TC0.00100RBSN-TRUEAluSz6SINE,Alu
chr1204521576AG0.00021MDM4+TRUEAluSgSINE,Alu
chr136770600GT0.00792THRAP3+FALSE(T)nSINE,Alu
chr1144932086GC0.00997NBPF20,PDE4DIP+,-FALSE
chr1184661932AG0.00063EDEM3-FALSE
chr42940265TC0.00413NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr122159774GA0.00257HSPG2-FALSE
chr237329214TC0.00081.FALSEAluJr4SINE,Alu
chr1049609751AG0.00979MAPK8+FALSE
chr177759578AG4.05543E-05AK5+FALSE
chr229023117AT0.00805PPP1CB+FALSE
chr1675479470TC3.73920E-07TMEM170A-TRUEAluJbSINE,Alu
chr9136209402AG0.00431MED22-FALSE(CAGGG)nSINE,Alu
chr1148753279GT0.00358.FALSE
chr268402797TA0.00656PNO1+FALSE
chr1179326882AG0.00020SOAT1+TRUEAluJoSINE,Alu
chr756131098TA0.00950CCT6A+FALSEL1M5SINE,Alu
chr3156258273TC0.00927SSR3-TRUEAluYk3SINE,Alu
chr1169824104GA0.00744SCYL3-FALSE
chr3122283293CG0.00071DTX3L,PARP9+,-FALSE
chr111347142CG0.00789UBIAD1+FALSE
chr110520764TC0.00501DFFA-TRUEAluSc8SINE,Alu
chr186117122TC0.00462ZNHIT6-FALSEAluSgSINE,Alu
chr5134236206AG0.00065TXNDC15+TRUEAluSqSINE,Alu
chr9125609941GA0.00043.FALSE
chr5135513089TA7.47633E-06SMAD5+FALSE
chr2137789499AG0.00889.FALSEAluJbSINE,Alu
chr812283440AG0.00041FAM86B2-FALSE
chr110041422AG0.00115NMNAT1+TRUEAluYj4SINE,Alu
chr1911256689TC9.47404E-06SPC24-TRUEAluJr4SINE,Alu
chr1120101744CA0.00540NAV2+FALSE
chr1144618144AG0.00725NBPF20,NBPF9+FALSE
chr41388115CG0.00682CRIPAK+FALSEL1MB4SINE,Alu
chr6114182986TA0.00316MARCKS+FALSE
chr136770602TG0.00441THRAP3+FALSE(T)nSINE,Alu
chr124086786AC0.00812TCEB3+FALSE
chr5151041883GA0.00343SPARC-FALSE
chr1475202412AG5.03546E-10FCF1+TRUEAluScSINE,Alu
chr119545147TG0.00510LOC101927895,EMC1+,-FALSE
chr310192617AG2.94246E-06VHL+TRUEAluSx1SINE,Alu
chr13395039GA0.00027ARHGEF16+FALSE
chr1197070776CT0.00698ASPM-FALSE
chr1224517842CT0.00014NVL-FALSE
chr1953155567TC0.00137ZNF83-TRUEAluSgSINE,Alu
chr3194124421AG0.00024ATP13A3-FALSE
chr211781593GT0.00551GREB1+FALSE
chr246612340GT0.00094EPAS1+FALSE
chr16281866AC0.00102ICMT-FALSE
chr263817855CG0.00096MDH1+FALSE
chr319992312AG0.00798RAB5A+FALSE
chr119953120GA0.00024MINOS1,MINOS1-NBL1+FALSE
chr2036147563TC0.00313BLCAP-TRUE
chr1230979247GA0.00137C1orf198-FALSE
chr417803616TC0.00046DCAF16-TRUEAluYSINE,Alu
chr2227660628TG0.00025IRS1-FALSE
chr1227211026CG0.00373CDC42BPA-FALSE
chr1464152516TC0.00011SGPP1-FALSE(TA)nSINE,Alu
chr12120898553AG0.00233GATC+TRUEAluYSINE,Alu
chr128826130AG0.00207PHACTR4+TRUEAluJbSINE,Alu
chr175288083TA0.00232RABEP1+FALSE
chr264327544GT0.00340PELI1-FALSE
chr17263417CT0.00675LOC105371430,C17orf97+,-FALSE
chr1225974645AG0.00984SRP9+TRUEAluJrSINE,Alu
chr16659505GA0.00405KLHL21-FALSE
chr1100489835AG0.00043SLC35A3+TRUEAluSgSINE,Alu
chr2176042865GT0.00887ATP5G3-FALSE
chr2109401285GA0.00087RANBP2+FALSE
chr1583659319AT0.00130FAM103A1,C15orf40+,-FALSE
chr5150647744AG0.00036GM2A+TRUEAluScSINE,Alu
chr1193054576TC0.00068TROVE2+FALSE(ATTTT)nSINE,Alu
chr1206669958GA0.00347IKBKE+FALSE
chr1114940216TG0.00148TRIM33-FALSE(T)nSINE,Alu
chr136068231TC0.00508PSMB2-TRUEAluScSINE,Alu
chr744841933AG0.00192PPIA+TRUEAluSxSINE,Alu
chr1201846630CA7.51318E-05IPO9+FALSE(CA)nSINE,Alu
chr4123816376AT0.00445FGF2,NUDT6+,-FALSE
chr4128995640GA0.00567LARP1B+FALSE
chr123408939TA1.04314E-06KDM1A+FALSE
chr136770605CT0.00041THRAP3+FALSE(T)nSINE,Alu
chr13729587AG0.00580CEP104-FALSE(AT)nSINE,Alu
chr1610623631TC1.36144E-05EMP2-TRUEAluSpSINE,Alu
chr3176739580TC4.09936E-06TBL1XR1-FALSE
chr11549354GA0.00132.FALSEHAL1SINE,Alu
chr5140564263CT0.00475PCDHB16+FALSE
chr110517653TC1.73226E-05.FALSEAluSx1SINE,Alu
chr178603279AG0.00089GIPC2+FALSE
chr1118170485TC0.00281FAM46C+FALSE(TG)nSINE,Alu
chr1118066459AG0.00788MAN1A2+FALSE
chr140539201AG0.00028PPT1-FALSE
chr1150208462AC9.89925E-05ANP32E-FALSE
chr261764920CA0.00662XPO1-FALSE
chr1060047608AG0.00356CISD1+FALSE(A)nSINE,Alu
chr1182686151TC0.00404RAB30-FALSE
chr153289759AG0.00329ZYG11B+TRUEAluSzSINE,Alu
chr237429737AG3.16512E-05CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr19329105TA0.00233H6PD+FALSE
chr1142688511TC0.00089.FALSE
chr970483778AT0.00026CBWD5-FALSE
chr299772813AG1.48642E-06LIPT1+TRUEAluSx1SINE,Alu
chr1117530213GT0.00256PTGFRN+FALSE
chr1765334846TC0.00456PSMD12-FALSEAluSqSINE,Alu
chr11595048TC0.00399CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr144463185TG0.00969SLC6A9-FALSE
chr153289759AG0.00383ZYG11B+TRUEAluSzSINE,Alu
chr126144435CG0.00131SEPN1+FALSE
chr1205320469GA0.00109KLHDC8A-FALSE
chr3183861750AC1.09807E-05EIF2B5+FALSE
chr131346203AC0.00050SDC3-FALSE
chr1160966353TC0.00011F11R-TRUEAluSgSINE,Alu
chr16948076CT0.00221CAMTA1+FALSEL2aSINE,Alu
chr16160958AG0.00967KCNAB2+FALSE
chr3172117458AC0.00011FNDC3B+FALSE
chr333185522CA1.53330E-10CRTAP+FALSEL2aSINE,Alu
chr195362514GT7.06346E-05CNN3-FALSE
chr3196556843GA4.00732E-06PAK2+FALSE
chr2204055454TC0.00293NBEAL1+FALSE
chr135648840GT0.00543SFPQ-FALSEAluSx3SINE,Alu
chr1145688672AT0.00770NBPF20,NBPF10,RNF115+FALSE
chr116889624TC0.00795NBPF1-TRUE
chr132687472GA0.00877TMEM234,EIF3I+,-FALSE
chr286249930TC0.00054LOC90784-TRUEAluJrSINE,Alu
chr1112003958TA0.00557ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr1544751338GA0.00374CTDSPL2+FALSE
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr16283348TC0.00247ICMT-TRUEAluSx3SINE,Alu
chr167874731TC0.00565SERBP1-TRUEAluSx3SINE,Alu
chr138327700TC0.00132INPP5B-TRUEAluSx3SINE,Alu
chr373116345TA5.66390E-05PPP4R2+FALSE
chr3196556141GA0.00534PAK2+FALSE
chr1203709034AG0.00049ATP2B4+FALSE
chr2025428669AG0.00023GINS1+TRUEAluJbSINE,Alu
chr314526653GT0.00936SLC6A6+FALSE
chr16585331TC0.00094NOL9-TRUEFAMSINE,Alu
chr1474526975TC0.00024BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr1469254646TC0.00181ZFP36L1-FALSE
chr2178406765TA0.00325AGPS+FALSE
chr132706126GA0.00932MTMR9LP-FALSE
chr119542679TC0.00738LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr154493443CA0.00872TMEM59-FALSEAluSz6SINE,Alu
chr185113229AG0.00080SSX2IP-FALSE
chr177759578AG0.00031AK5+FALSE
chr579923843TC0.00229DHFR-TRUEAluSpSINE,Alu
chr862626962CT0.00823ASPH-FALSE
chr177759578AG0.00404AK5+FALSE
chr1150783968TA0.00368ARNT-FALSE
chr132372360CT0.00697PTP4A2-FALSE(CA)nSINE,Alu
chr110520130TC0.00355.FALSEAluSxSINE,Alu
chr124999468GT0.00075SRRM1+FALSE(T)nSINE,Alu
chr1116609833GA0.00012SLC22A15+FALSE
chr3141667690TC0.00018TFDP2-TRUEAluYSINE,Alu
chr1244181367GA0.00608IRAK4+FALSEMLT1E1ASINE,Alu
chr167895926AG0.00705SERBP1-FALSE
chr310193732AG0.00472VHL+TRUEAluJrSINE,Alu
chr310004768GA3.85967E-05EMC3-FALSETigger14aSINE,Alu
chr110520902AT0.00032DFFA-FALSE
chr1160112392GA0.00701ATP1A2+FALSEAluSx3SINE,Alu
chr1204526611AG0.00402MDM4+TRUEAluSxSINE,Alu
chr9102744698GT0.00301ERP44-FALSE
chr1204525744AG0.00010MDM4+TRUEAluSzSINE,Alu
chr1145369589TC0.00128NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr1115110683AC0.00168BCAS2-FALSE
chr452888499GA0.00366SGCB-FALSE
chr317201882CT0.00259TBC1D5-FALSE
chr1591044385GT0.00440IQGAP1+FALSE
chr2134731077AG0.00926IFNAR1+TRUEAluJrSINE,Alu
chr122854931CA0.00238ZBTB40+FALSEA-richSINE,Alu
chr19331101AG3.95613E-06H6PD+FALSEAluSxSINE,Alu
chr3179117270TC0.00478GNB4-TRUEAluSzSINE,Alu
chr1108728562AT0.00228SLC25A24-FALSE
chr2218571431AG0.00158PEX26+TRUEAluSzSINE,Alu
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr126796922GC0.00401DHDDS+FALSEFLAM_CSINE,Alu
chr1148556753GA0.00272.FALSE
chr2176792488GT0.00195LNPK-FALSE
chr190496713AG0.00677ZNF326+FALSE
chr16283306TC0.00047ICMT-TRUEAluSx3SINE,Alu
chr484525986GT0.00081GPAT3+FALSE(TTGTT)nSINE,Alu
chr19294903CG0.00147H6PD+FALSE
chr177556766TA0.00576PIGK-FALSE
chr1168523055TC0.00524CPT1A-TRUEAluYSINE,Alu
chr139305002AT0.00089RRAGC-FALSE
chr2208619742AG1.70106E-07CCNYL1+TRUEAluJbSINE,Alu
chr110519064TC0.00515.FALSEAluSx3SINE,Alu
chr103208557AG0.00128PITRM1-FALSE
chr1921474857TC0.00131ZNF708-TRUEAluScSINE,Alu
chr228639641CG0.00431.FALSE
chr1742876398TC0.00697GJC1-FALSEAluSz6SINE,Alu
chr23592638TC0.00164RNASEH1-TRUEAluSz6SINE,Alu
chr826492397CT0.00709DPYSL2+FALSE
chr116893691CA0.00764NBPF1-FALSE
chr2174090928GC0.00852ZAK,MLK7-AS1+,-FALSE
chr1149913731TC0.00198OTUD7B-TRUEMER96BSINE,Alu
chr575003678TC0.00435POC5-FALSE
chr217942775TA0.00367GEN1+FALSE
chr7120740103GT0.00601CPED1+FALSE
chr1942376692AG0.00540.FALSEAluSpSINE,Alu
chr1179042544AG0.00722FAM20B+TRUEAluSx1SINE,Alu
chr246612340GT3.13955E-05EPAS1+FALSE
chr299813003AG0.00046MRPL30+TRUEAluJbSINE,Alu
chr11001422GT0.00998.FALSELTR13ASINE,Alu

Differential Expression Gene Analysis