Dataset Overview
RBP
EIF4A3
Knock-Method
shRNA
RBP Family
DEAD
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR957EEG
Platform
HiSeq
Pubmed ID
32252787
EIF4A3 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of EIF4A3
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
40.38
103.76
1.18448
2.00043E-47
4.91134E-46
A1CF
29.02
43.16
1.14377
1.82940E-66
8.01099E-65
AACS
17.52
9.2
-1.09541
6.36088E-43
1.31511E-41
AADAC
0.87
2.49
1.42189
1.40863E-10
5.02770E-10
AADAT
2.45
4.96
0.72027
8.15826E-07
2.04201E-06
AAED1
4.64
3.77
-0.52926
0.00013
0.00025
AAGAB
4.83
8.45
0.65498
2.02991E-09
6.51092E-09
AAK1
1.2
3.5
1.57933
1.18792E-26
1.17264E-25
AAMDC
27.35
42.47
0.51043
2.19474E-05
4.68932E-05
AAR2
22.2
37.88
0.56714
2.78809E-14
1.33948E-13
Showing 1 to 10 of 9,781 entries
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Function Analysis of Target Genes of EIF4A3
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCB1
87170672_87170780_87168583_87168661_87173444_87173591
0.00001
-0.377
DataSet_01_424
View details
ABCG5
44051703_44051898_44051357_44051571_44052027_44052157
0.00386
-0.083
DataSet_01_424
View details
ABI1
27044583_27044670_27040526_27040712_27047990_27048167
0.00711
-0.22
DataSet_01_424
View details
AC022816.2
14280600_14280738_14277455_14277545_14285334_14285418
0.00575
0.311
DataSet_01_424
View details
ACAA1
38167652_38167832_38167316_38167372_38168000_38168191
0.00166
-0.076
DataSet_01_424
View details
ACAA1
38167652_38167843_38167159_38167372_38168000_38168191
0.00561
-0.086
DataSet_01_424
View details
ACIN1
23532137_23532283_23531641_23531713_23532644_23532786
0.00011
-0.521
DataSet_01_424
View details
ACSL4
108902582_108902740_108887273_108887415_108906439_108906631
0.00000
-0.149
DataSet_01_424
View details
ACSL4
108934231_108934360_108926364_108926781_108939372_108939425
0.00214
-0.263
DataSet_01_424
View details
ACTR1A
104241593_104241655_104240888_104240929_104242767_104242860
0.00934
-0.107
DataSet_01_424
View details
Showing 1 to 10 of 510 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9254042_9254270_9256834_9256996_9253739_9253803
0.00011
-0.088
DataSet_01_424
View details
ACAA1
38169276_38169357_38170780_38170879_38167652_38168191
0.00457
0.084
DataSet_01_424
View details
ACAT2
160189542_160189660_160196201_160196345_160188036_160188218
0.00499
0.083
DataSet_01_424
View details
ACLY
40068672_40068795_40069967_40070153_40066474_40066537
0.00001
0.177
DataSet_01_424
View details
ACLY
40068672_40068795_40069967_40070149_40066474_40066537
0.00010
0.147
DataSet_01_424
View details
ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00005
-0.062
DataSet_01_424
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ADD1
2910241_2910331_2916610_2916767_2909469_2909571
0.00004
-0.145
DataSet_01_424
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AFMID
76198783_76198832_76200908_76200981_76187050_76187141
0.00000
0.475
DataSet_01_424
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AFMID
76200908_76200981_76201173_76201271_76198783_76198832
0.00018
0.166
DataSet_01_424
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AFP
74306318_74306530_74309063_74309161_74303890_74304023
0.00000
-0.14
DataSet_01_424
View details
Showing 1 to 10 of 210 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101577064_101577241_101577064_101577156_101578628_101578714
0.00165
-0.048
DataSet_01_424
View details
ACAA1
38167652_38168191_38168000_38168191_38167159_38167372
0.00460
-0.089
DataSet_01_424
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ACSS2
33508341_33508563_33508341_33508512_33508808_33508871
0.00105
0.132
DataSet_01_424
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ALB
74275071_74275183_74275071_74275140_74276028_74276085
0.00096
0.016
DataSet_01_424
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ALDH1A1
75520873_75520948_75520929_75520948_75515577_75516196
0.00000
-0.234
DataSet_01_424
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ALDOA
30078770_30080299_30078770_30078982_30080626_30080710
0.00001
-0.526
DataSet_01_424
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AMBP
116823703_116823871_116823754_116823871_116822406_116822550
0.00000
-0.53
DataSet_01_424
View details
ANKZF1
220100182_220100343_220100182_220100307_220100429_220100597
0.00361
0.471
DataSet_01_424
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AP1G2
24033714_24033840_24033770_24033840_24033541_24033597
0.00540
0.03
DataSet_01_424
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AP1G2
24035024_24035369_24035272_24035369_24034814_24034910
0.00650
-0.107
DataSet_01_424
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Showing 1 to 10 of 67 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCD4
74759533_74759618_74759533_74759572_74761850_74761901
0.00481
-0.147
DataSet_01_424
View details
ACSL4
108926364_108926781_108926364_108926604_108934231_108934360
0.00427
0.139
DataSet_01_424
View details
AFMID
76200736_76200934_76200908_76200934_76198783_76198832
0.00030
-0.213
DataSet_01_424
View details
AHSG
186338374_186339089_186338883_186339089_186336285_186336426
0.00515
-0.06
DataSet_01_424
View details
AKAP8L
15514285_15514393_15514285_15514366_15514468_15514526
0.00035
0.457
DataSet_01_424
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ALB
74283804_74284028_74283982_74284028_74283255_74283386
0.00160
-0.5
DataSet_01_424
View details
APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00000
-0.021
DataSet_01_424
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APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00000
-0.046
DataSet_01_424
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APOA2
161193139_161193247_161193139_161193215_161193308_161193349
0.00025
0.294
DataSet_01_424
View details
ARSE
2876314_2876476_2876314_2876464_2882264_2882305
0.00310
-0.308
DataSet_01_424
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Showing 1 to 10 of 86 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38167316_38168191_38167316_38167372_38167652_38168191
0.00004
0.059
DataSet_01_424
View details
ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00002
0.035
DataSet_01_424
View details
ACADVL
7125985_7126556_7125985_7126184_7126451_7126556
0.00256
0.104
DataSet_01_424
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ACTB
5568791_5569294_5568791_5569031_5569165_5569294
0.00326
0.012
DataSet_01_424
View details
ACTR1B
98274889_98275466_98274889_98275106_98275341_98275466
0.00000
0.252
DataSet_01_424
View details
ADRBK1
67049292_67050013_67049292_67049423_67049741_67050013
0.00627
0.11
DataSet_01_424
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AFMID
76201576_76201819_76201576_76201599_76201683_76201819
0.00027
0.278
DataSet_01_424
View details
AFMID
76200736_76200934_76200736_76200822_76200908_76200934
0.00088
0.329
DataSet_01_424
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AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00144
-0.164
DataSet_01_424
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AKAP8L
15514285_15514526_15514285_15514366_15514468_15514526
0.00850
0.108
DataSet_01_424
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
79356178
C
A
0.00678
ADGRL4
-
FALSE
chr1
16203171
C
T
3.13656E-06
SPEN
+
FALSE
chr1
26755303
A
G
0.00129
LIN28A
+
TRUE
AluSx1
SINE,Alu
chr1
2115914
G
T
0.00970
PRKCZ,FAAP20
+,-
FALSE
chr1
9642827
G
A
0.00521
SLC25A33
+
FALSE
chr1
160967857
T
C
0.00806
F11R
-
TRUE
AluSp
SINE,Alu
chr1
9160900
T
C
0.00010
.
FALSE
AluJb
SINE,Alu
chr1
109535117
C
T
0.00211
WDR47
-
FALSE
chr1
15988702
T
C
0.00362
.
FALSE
chr1
10520258
T
C
0.00746
.
FALSE
AluSx
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression