Dataset Overview
RBPUPF1
Knock-MethodshRNA
RBP FamilyUPF1_Zn_bind
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR689MIY
PlatformHiSeq
Pubmed ID32252787

UPF1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of UPF1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of UPF1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr192941357AG0.00296GFI1-FALSE
chr1179852074TC0.00338TOR1AIP1+FALSE
chr996438967GC0.00648PHF2+FALSE(CTCCAC)nSINE,Alu
chr744800040CA0.00565ZMIZ2+FALSE
chr146830257CT0.00208NSUN4+FALSEAluSx1SINE,Alu
chr116889864CA0.00063NBPF1-FALSE
chr1346530764TG0.00385.FALSE
chr1206579798TC0.00476SRGAP2+FALSE
chr35258985TC1.48069E-09EDEM1+FALSE
chr76064010CA0.00304EIF2AK1-FALSE
chr1182353198AT0.00473GLUL-FALSE
chr5178293266GA0.00924ZNF354B+FALSE
chr1628620957TC0.00753SULT1A1-TRUEAluJrSINE,Alu
chr1145284138GA0.00382NBPF20,NOTCH2NL+FALSE(TG)nSINE,Alu
chr255516939GT0.00628CCDC88A-FALSE(GA)nSINE,Alu
chr1467852067AG2.77652E-05EIF2S1+TRUEAluJbSINE,Alu
chr3195393406CT0.00690SDHAP2+FALSE
chr116901668TC0.00421NBPF1-FALSE
chr110042988AG0.00095NMNAT1+TRUEAluScSINE,Alu
chr6116256595CA5.71236E-05.FALSE
chr581571878AT8.61300E-05RPS23-FALSE
chr1145313405CT0.00322NBPF20,NBPF10+FALSE
chr110518037TC0.00285.FALSEAluJrSINE,Alu
chr132479707GA0.00000KHDRBS1+FALSE
chr126755455AG0.00342LIN28A+TRUEAluScSINE,Alu
chr1144833382CT0.00325NBPF20+FALSEL1MEcSINE,Alu
chr1780899281GA0.00053TBCD+FALSE
chr1475203097AG1.28940E-05FCF1+TRUEAluSxSINE,Alu
chr185786957TG0.00959DDAH1-FALSE
chr136031860GT0.00564NCDN+FALSE
chr1223178477CT0.00519DISP1+FALSE
chr2191556849AT0.00158NAB1+FALSE
chr452888499GA8.91315E-05SGCB-FALSE
chr1114226255GA0.00381MAGI3+FALSE
chr3172350135AT9.93187E-07NCEH1-FALSE
chr110517659TC0.00012.FALSEAluSx1SINE,Alu
chr110519946TC0.00080.FALSEAluJrSINE,Alu
chr1109747415AG0.00549KIAA1324+TRUEAluJr4SINE,Alu
chr8146280802CT1.51873E-05C8orf33+FALSELTR13SINE,Alu
chr89639522AG0.00823TNKS+TRUEMER53SINE,Alu
chr110519982TC0.00417.FALSEAluJrSINE,Alu
chr417802890TC0.00303DCAF16-TRUEAluSzSINE,Alu
chr153288870AG0.00501ZYG11B+TRUEAluJoSINE,Alu
chr128825418AG0.00725PHACTR4+TRUEAluSgSINE,Alu
chr3196659884GT0.00217SENP5+FALSE
chr6160100931TC0.00215SOD2-TRUEAluSzSINE,Alu
chr116929327CT0.00646NBPF1-FALSEERVL-E-intSINE,Alu
chrX152916229GA0.00809DUSP9+FALSE
chr2025427856AG0.00094GINS1+FALSEAluSzSINE,Alu
chr1201846627AT0.00571IPO9+FALSE(CA)nSINE,Alu
chr128661831AG9.37902E-09MED18+TRUEAluSgSINE,Alu
chr1688789699AC0.00936PIEZO1-FALSE
chr2170103351GT0.00139LRP2-FALSE
chr19161365TC4.68504E-05.FALSEAluSxSINE,Alu
chr119586458AG0.00029MRTO4+TRUEAluSzSINE,Alu
chr6150047376TC0.00612NUP43-TRUEAluScSINE,Alu
chr136068325TC0.00638PSMB2-TRUEAluScSINE,Alu
chr1742877584TC0.00489GJC1-TRUEAluSgSINE,Alu
chr119543459TC0.00395LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr5157184013AG0.00631LSM11+TRUEAluYSINE,Alu
chr1179044242AG0.00335FAM20B+TRUEAluSxSINE,Alu
chrX118920477AT0.00529RPL39-FALSE
chr23597974TC1.93309E-05RNASEH1-FALSE
chr1179326588AG0.00563SOAT1+TRUEAluSgSINE,Alu
chr219908316CT0.00719TEKT4P2-FALSE
chr237328082TC0.00243.FALSE
chr1936260451AG0.00854.FALSEAluYSINE,Alu
chr119934758CG1.75422E-05MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr488814756CT0.00145.FALSE
chr13729217TC0.00030CEP104-TRUEAluSx3SINE,Alu
chr347953733CA0.00057MAP4-FALSE
chr1738438362GA0.00016WIPF2+FALSEA-richSINE,Alu
chr2201253956AG0.00071SPATS2L+FALSE
chr1330084952GA0.00045SLC7A1-FALSE
chr123240263GA5.22984E-05EPHB2+FALSE
chr5118811533GA0.00781HSD17B4+FALSE
chr16614230GA0.00509NOL9-FALSE
chr13546132GA0.00113TPRG1L+FALSEAluSzSINE,Alu
chr126755229AG0.00318LIN28A+FALSEAluSx1SINE,Alu
chr152381350TG4.39398E-08RAB3B-FALSE
chr12133298255AG0.00016PGAM5+TRUEAluSpSINE,Alu
chr2128060859TA0.00016MAP3K2-FALSE
chr564097145CG0.00361CWC27+FALSE
chr466439707TC0.00148EPHA5-FALSE
chr153712727CT0.00313LRP8-FALSE
chr841401571TA0.00240LOC102723729,GINS4+,-FALSE
chr127205634TC0.00025.FALSEFLAM_ASINE,Alu
chr2128644574AG0.00163.FALSE
chr4177252327AG2.51883E-09SPCS3+TRUE
chrX118672641TC0.00027CXorf56-TRUEAluSxSINE,Alu
chr110520532TC0.00142.FALSEAluSx1SINE,Alu
chr120976163CT0.00091PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1150594611GT0.00329ENSA-FALSE
chr211323106GT0.00860ROCK2-FALSE(TA)nSINE,Alu
chr1958374130CT0.00124ZNF587+FALSE
chr1060047608AG0.00356CISD1+FALSE(A)nSINE,Alu
chr2233446265TC0.00177EIF4E2+FALSE
chr738764340TC0.00630VPS41-TRUEAluSpSINE,Alu
chr315113847TC0.00026RBSN-TRUEAluSz6SINE,Alu
chr1115249239GA1.76451E-06NRAS-FALSE
chr647501448TC0.00017CD2AP+FALSE
chr187328400CT0.00755SEP15-FALSE
chr127992800CA5.71645E-05IFI6-FALSEFAMSINE,Alu
chr128835937AG0.00061SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr3194362721GA5.25740E-07LSG1-FALSE
chr136533368AG0.00635.FALSEAluSxSINE,Alu
chr637138022CG0.00953PIM1+FALSE
chr1156713558GA8.10199E-06HDGF-FALSE
chr1120165038AG0.00926ZNF697-FALSE
chr5149363214AG0.00040SLC26A2+TRUEAluJrSINE,Alu
chr352800284TC6.08396E-05NEK4-FALSE
chr3160213318TG0.00215KPNA4-FALSE
chr8144332082TC7.73207E-05ZFP41+FALSE
chr119543353TC0.00091LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2101623611AC0.00826RPL31+FALSE
chr1149581866CG0.00774LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chr12125511942AG0.00596THRIL-FALSEAluSx1SINE,Alu
chr1144606838AG0.00025NBPF20+FALSE
chr1749042388TC2.65954E-10SPAG9-TRUEAluJbSINE,Alu
chr1148023637CT0.00014NBPF8-FALSE
chr178342729AG0.00175MIGA1+TRUEFRAMSINE,Alu
chr1949468569GT0.00266FTL+FALSE
chrX24095285AG0.00135EIF2S3+TRUEAluSxSINE,Alu
chr264119873AT0.00492VPS54-FALSE
chr1533064791GA0.00203FMN1-FALSE
chr167874849TC7.36358E-05SERBP1-TRUEAluSxSINE,Alu
chr13745924GA0.00612CEP104-FALSE
chr7138730361TC0.00316ZC3HAV1-FALSEL2-1_AMiSINE,Alu
chr2188330198CA0.00091TFPI-FALSEAluJbSINE,Alu
chr314986111TC0.00000FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1160967848TC0.00200F11R-TRUEAluSpSINE,Alu
chr5150647744AG0.00036GM2A+TRUEAluScSINE,Alu
chr2128620436CT0.00342AMMECR1L-FALSE
chr237331753TC0.00026.FALSEAluJbSINE,Alu
chr112073252AG0.00990MFN2+FALSE
chr126449340GA0.00711PDIK1L+FALSE
chr314986098TC0.00000FGD5-AS1-TRUEFLAM_CSINE,Alu
chr570503941CA0.00130.FALSE
chr133149496AG0.00469SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr119954014GT0.00055MINOS1,MINOS1-NBL1+FALSEL2cSINE,Alu
chr152306079TA0.00708NRDC-FALSE(TCA)nSINE,Alu
chr3196670095CA1.97381E-07NCBP2-AS2+FALSE
chr152375677TC0.00542RAB3B-FALSEMIRbSINE,Alu
chr2219460472TC0.00187CNOT9+FALSE
chr136067925TC2.33961E-06PSMB2-TRUEAluSzSINE,Alu
chr16583066TC0.00173NOL9-TRUEAluSx4SINE,Alu
chr138326774TC0.00664INPP5B-TRUEAluJrSINE,Alu
chr1110596904AG0.00364STRIP1+FALSE
chr1563988357CG0.00539HERC1-FALSE
chr1145290818CG0.00931NBPF20+FALSE
chr153291434AG0.00124ZYG11B+TRUEAluJrSINE,Alu
chr136322433GA0.00663AGO4+FALSE
chr1063852210CT0.00324ARID5B+FALSE
chr1149913513TC0.00495OTUD7B-TRUEMER96BSINE,Alu
chr4169910101CT0.00026CBR4-FALSE
chr1145512073AG0.00066NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2206983075TC0.00083.FALSEAluJbSINE,Alu
chr128826150AG0.00048PHACTR4+TRUEAluJbSINE,Alu
chr1113243096GT0.00114MOV10+FALSE
chr133149373AG0.00239SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr16282400TC0.00321ICMT-TRUEAluSzSINE,Alu
chr204680094CT0.00438PRNP+FALSE
chr1148556743GA0.00402.FALSE
chr125894472CG0.00063LDLRAP1+FALSEMIRbSINE,Alu
chr1138156GT0.00177LOC729737-FALSE
chr2202031806AT0.00543CFLAR+FALSE
chr1204525713AG0.00501MDM4+TRUEAluSzSINE,Alu
chr1115299504GT0.00067CSDE1-FALSE
chr1205739266CT0.00069RAB29-FALSE
chr457326291AG0.00424PAICS+TRUEAluJrSINE,Alu
chr119542310TC0.00873LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr119545144GT0.00071LOC101927895,EMC1+,-FALSE
chr5170832637CT0.00071NPM1+FALSE
chr333185036GA0.00573CRTAP+FALSEL2aSINE,Alu
chr155062960GA0.00542ACOT11+FALSE
chr11152601AG0.00075SDF4-FALSE
chr1453242639TC1.43651E-05GNPNAT1-TRUEAluJrSINE,Alu
chr3183900836GA0.00658AP2M1+FALSE
chr3107765249TC0.00156CD47-FALSE
chr261277384AG0.00339PEX13+TRUEAluSxSINE,Alu
chr1144931392GA0.00172NBPF20,PDE4DIP+,-FALSE
chr170718271GA0.00273.FALSE
chr1939433139TG0.00235FBXO17-FALSEAluJbSINE,Alu
chr1942376710AG1.82395E-05.FALSEAluSpSINE,Alu
chr127182750GC0.00141.FALSE
chr2242512159AG0.00243BOK+FALSE
chr117313654CT0.00714ATP13A2-FALSE
chr2217366195CA0.00929.FALSE
chr126144435CG0.00131SEPN1+FALSE
chr146521559AT0.00177PIK3R3-FALSE
chr341281407GT0.00011CTNNB1+FALSE
chr111119950GA4.66412E-05SRM-FALSE
chr729960812TA1.34773E-06SCRN1-FALSE
chr116909161TC0.00718NBPF1-FALSE
chr1298942808AG0.00019TMPO+TRUEAluScSINE,Alu
chr167874689TC0.00053SERBP1-TRUEAluSx3SINE,Alu
chr2100019496AG0.00789REV1-FALSE
chr153289759AG0.00329ZYG11B+TRUEAluSzSINE,Alu
chr133149443AG0.00327SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr5149829072GT0.00816RPS14-FALSE
chr1144614842CG0.00015NBPF20+FALSE
chr119499560TC0.00226UBR4-FALSE
chr1540955103AG0.00372.FALSEAluJbSINE,Alu
chr1144604425CT0.00299NBPF20+FALSE
chr1725640011AG0.00228WSB1+TRUEAluSxSINE,Alu
chr119234103GA0.00014IFFO2-FALSE
chr1155214017CA0.00261GBA-FALSEAluSx3SINE,Alu
chr75085646CT0.00168RBAK-RBAKDN,RBAK+FALSE
chr111084103TA0.00162TARDBP+FALSE
chr1160967890TC0.00876F11R-TRUEAluSpSINE,Alu
chr344791554TC7.29341E-07KIAA1143-FALSEAluJrSINE,Alu
chr110517653TC0.00792.FALSEAluSx1SINE,Alu
chr1206516261CT0.00179SRGAP2+FALSE
chr56633042CT0.00348NSUN2-FALSE
chr1688767769GC0.00420RNF166-FALSE
chr1153720690GA0.00550INTS3+FALSE
chr16583593TC0.00088NOL9-TRUEAluSqSINE,Alu
chr165692499CT0.00930AK4+FALSE(T)nSINE,Alu

Differential Expression Gene Analysis