Dataset Overview
RBP
AKAP8
Knock-Method
shRNA
RBP Family
AKAP95
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR958KSY
Platform
HiSeq
Pubmed ID
32252787
AKAP8 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of AKAP8
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
47.59
26.41
-0.51642
6.57184E-09
3.34246E-08
A2M
3527.82
4751.69
0.58828
3.02033E-13
2.52646E-12
A4GALT
0.64
2.05
1.40481
2.34062E-06
8.44687E-06
AAAS
18.34
20.45
0.21244
0.04275
0.06888
AADAT
9.24
4.34
-0.80873
1.22536E-08
5.98959E-08
AAGAB
10.36
8.31
-0.33557
0.03088
0.05160
AAK1
4.32
7.69
0.70822
1.11543E-09
6.30020E-09
AAR2
9.53
13.85
0.42050
1.90763E-05
5.98686E-05
AARS
74.14
89.26
0.24599
0.00893
0.01690
AASDHPPT
17.76
11.8
-0.40282
0.00011
0.00029
Showing 1 to 10 of 8,303 entries
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Function Analysis of Target Genes of AKAP8
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52575765_52576039_52570799_52570936_52580311_52580409
0.00189
-0.134
DataSet_01_43
View details
A2M
9265230_9265282_9264904_9265132_9265955_9266139
0.00822
0.5
DataSet_01_43
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AAR2
34824803_34824888_34824386_34824425_34827742_34828547
0.00788
-0.072
DataSet_01_43
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ABLIM1
116213137_116213242_116211382_116211430_116225456_116225586
0.00745
0.032
DataSet_01_43
View details
ACAT2
160189542_160189582_160183950_160184085_160196201_160196339
0.00366
0.013
DataSet_01_43
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ADH4
100062691_100062833_100057616_100057848_100063829_100063931
0.00131
-0.247
DataSet_01_43
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ADRM1
60883423_60883526_60883038_60883234_60883710_60883918
0.00163
0.037
DataSet_01_43
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AFMID
76202026_76202131_76198783_76198832_76202991_76203782
0.00491
-0.084
DataSet_01_43
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AFP
74313330_74313393_74309063_74309161_74315051_74315184
0.00000
0.009
DataSet_01_43
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AFP
74310709_74310839_74309063_74309161_74315051_74315184
0.00003
0.011
DataSet_01_43
View details
Showing 1 to 10 of 172 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACIN1
23559730_23559842_23562687_23562753_23550956_23551045
0.00562
0.159
DataSet_01_43
View details
AHRR
306716_306875_311407_311517_304298_304336
0.00445
0.158
DataSet_01_43
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AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00000
-0.013
DataSet_01_43
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AHSG
186336285_186336426_186337645_186337729_186334975_186335139
0.00016
-0.007
DataSet_01_43
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AHSG
186336300_186336426_186337645_186337729_186334975_186335139
0.00018
-0.006
DataSet_01_43
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AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00025
-0.007
DataSet_01_43
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00073
-0.007
DataSet_01_43
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ALDH7A1
125891622_125891707_125894931_125895026_125889978_125890085
0.00631
-0.074
DataSet_01_43
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ANAPC1
112630884_112630981_112631189_112631241_112630206_112630289
0.00839
-0.208
DataSet_01_43
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AP1G2
24035024_24035238_24035272_24035353_24034814_24034910
0.00298
-0.037
DataSet_01_43
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Showing 1 to 10 of 68 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSS2
33462744_33462940_33462744_33462930_33470596_33470792
0.00809
0.174
DataSet_01_43
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ACTL6A
179280710_179280905_179280710_179280761_179287611_179287688
0.00952
-0.165
DataSet_01_43
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ALDH2
112229109_112229300_112229109_112229223_112229864_112230002
0.00210
0.223
DataSet_01_43
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AP1G2
24036805_24036992_24036947_24036992_24036319_24036528
0.00610
-0.04
DataSet_01_43
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AP1G2
24035024_24035369_24035272_24035369_24034814_24034910
0.00853
0.058
DataSet_01_43
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APOM
31624248_31624410_31624248_31624403_31625001_31625075
0.00275
-0.027
DataSet_01_43
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ATP5G1
46970178_46970272_46970178_46970202_46970770_46970818
0.00026
-0.069
DataSet_01_43
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BTF3
72794232_72794411_72794232_72794383_72794958_72795027
0.00696
0.007
DataSet_01_43
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CNBP
128890476_128890614_128890497_128890614_128890288_128890381
0.00009
0.156
DataSet_01_43
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COL27A1
117063724_117063880_117063724_117063742_117063961_117063997
0.00622
0.022
DataSet_01_43
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Showing 1 to 10 of 24 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9225248_9225320_9225248_9225317_9225392_9225467
0.00373
-0.649
DataSet_01_43
View details
AC040977.1
6915927_6916096_6915927_6916076_6916984_6917062
0.00711
0.037
DataSet_01_43
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AC040977.1
6915927_6916080_6915927_6916076_6916984_6917062
0.00534
0.031
DataSet_01_43
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ACSL4
108926364_108926895_108926364_108926781_108939372_108939425
0.00977
-0.418
DataSet_01_43
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AP000525.9
16189263_16189411_16189263_16189378_16190680_16190791
0.00772
0.178
DataSet_01_43
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APOA2
161193151_161193247_161193151_161193215_161193384_161193418
0.00044
-0.027
DataSet_01_43
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AUP1
74754067_74754279_74754067_74754186_74754374_74754490
0.00695
0.033
DataSet_01_43
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AUP1
74754067_74754272_74754067_74754186_74754374_74754490
0.00846
0.037
DataSet_01_43
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BAHD1
40754110_40754493_40754113_40754493_40750649_40752095
0.00962
-0.324
DataSet_01_43
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BIRC5
76212046_76212862_76212744_76212862_76210760_76210870
0.00851
-0.063
DataSet_01_43
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Showing 1 to 10 of 29 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCD4
74763035_74764772_74763035_74763152_74764632_74764772
0.00066
0.181
DataSet_01_43
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ACADVL
7127639_7127871_7127639_7127712_7127802_7127871
0.00491
0.044
DataSet_01_43
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00501
-0.006
DataSet_01_43
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AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00071
0.138
DataSet_01_43
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AMICA1
118067449_118068806_118067449_118067536_118068712_118068806
0.00827
-0.115
DataSet_01_43
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AMT
49457142_49457775_49457142_49457221_49457643_49457775
0.00871
0.184
DataSet_01_43
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AP1G2
24034814_24035369_24034814_24034910_24035272_24035369
0.00187
0.091
DataSet_01_43
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AP1G2
24030720_24031624_24030720_24030844_24031170_24031624
0.00748
0.113
DataSet_01_43
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ARAP1
72407593_72408240_72407593_72407699_72408027_72408240
0.00101
0.132
DataSet_01_43
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CHMP2A
59062932_59063334_59062932_59063143_59063272_59063334
0.00387
-0.031
DataSet_01_43
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
120497841
T
C
0.00673
NOTCH2
-
FALSE
chr1
214529170
T
C
0.00670
PTPN14
-
TRUE
chr1
15989141
C
G
0.00364
.
FALSE
chr1
36529549
A
G
0.00806
.
FALSE
AluJr
SINE,Alu
chr1
59246520
A
C
7.56706E-05
JUN
-
FALSE
chr1
19232211
G
A
0.00552
IFFO2
-
FALSE
(GT)n
SINE,Alu
chr1
6659505
G
A
0.00405
KLHL21
-
FALSE
chr1
53288924
A
G
0.00099
ZYG11B
+
TRUE
AluJo
SINE,Alu
chr1
24022910
G
A
0.00036
RPL11
+
FALSE
chr1
145513090
A
G
0.00017
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluSz6
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression