Dataset Overview
RBP
IGF2BP1
Knock-Method
shRNA
RBP Family
KH_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR708GKW
Platform
HiSeq
Pubmed ID
32252787
IGF2BP1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of IGF2BP1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
29.34
39.01
0.86991
3.23239E-19
2.64425E-18
A2M
2342.22
3214.76
0.39023
7.60956E-06
1.85416E-05
AAAS
28.52
26.66
-0.25477
0.04191
0.05999
AACS
15.41
14.03
-0.23100
0.03357
0.04880
AAGAB
9.04
11.2
0.32908
0.02279
0.03417
AAK1
2.94
2.99
0.40729
0.01294
0.02017
AAMDC
19.44
30.98
0.63688
0.00014
0.00029
AARS
40.96
25.61
-0.73102
4.27099E-13
2.15250E-12
AARS2
5.21
4.13
-0.35403
0.01019
0.01618
AASDH
5.11
7.98
0.58216
0.00011
0.00022
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Function Analysis of Target Genes of IGF2BP1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
No data available in table
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
No data available in table
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
35646125
C
T
0.00027
SFPQ
-
FALSE
chr1
1152309
A
T
0.00035
SDF4
-
FALSE
chr1
6282318
T
C
0.00418
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
38155699
T
G
0.00734
C1orf109
-
FALSE
AluSx1
SINE,Alu
chr1
19543352
T
C
0.00715
LOC101927895,EMC1
+,-
FALSE
AluJb
SINE,Alu
chr1
17085028
G
A
0.00803
MST1L,LOC102724562
-
FALSE
chr1
25894468
C
G
0.00265
LDLRAP1
+
FALSE
MIRb
SINE,Alu
chr1
202848587
G
A
2.63176E-05
RABIF
-
FALSE
chr1
19441410
G
A
7.84348E-05
UBR4
-
FALSE
chr1
45975574
A
G
0.00890
MMACHC
+
TRUE
AluSx4
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression