Dataset Overview
RBPXPO5
Knock-MethodshRNA
RBP FamilyXpo1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR778RWJ
PlatformHiSeq
Pubmed ID32252787

XPO5 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of XPO5
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of XPO5


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1269160574AG0.00891.FALSEAluJbSINE,Alu
chr136533368AG0.00635.FALSEAluSxSINE,Alu
chr1160966434TC0.00175F11R-TRUEAluSgSINE,Alu
chr581571877CT0.00033RPS23-FALSE
chr1145689717AG7.73781E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr1144606963GT0.00965NBPF20+FALSE
chr12125511958AG0.00494THRIL-FALSEAluSx1SINE,Alu
chr132799439CT0.00239MARCKSL1-FALSE
chr5149363414AG0.00503SLC26A2+TRUEAluJrSINE,Alu
chr1145291108AC0.00827NBPF20+FALSE
chr410443061GT0.00057ZNF518B-FALSE
chr39829171GA0.00730TADA3-FALSE
chr133148214AG0.00295SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr2144329971AG9.72102E-05.FALSEAluSx3SINE,Alu
chr5151041886TG0.00176SPARC-FALSE
chr167896025GA5.77574E-06SERBP1-FALSE
chr151822219GA0.00017EPS15-FALSE
chr729961659CG7.23387E-07SCRN1-FALSE
chr426433556AC3.10862E-15RBPJ+FALSE
chr127879798AG0.00899AHDC1-FALSEMIRbSINE,Alu
chr345636335AG0.00262LIMD1+FALSE(AC)nSINE,Alu
chr127045885AC0.00473ATN1+FALSE(CAG)nSINE,Alu
chr291843471CT0.00095LOC654342-FALSE
chr2133032035TA1.90109E-05SOD1+FALSE
chr3181430146CA0.00256SOX2-OT,SOX2+FALSE
chr315113810TC0.00201RBSN-TRUEAluSz6SINE,Alu
chr119543353TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1675479484TC1.12347E-07TMEM170A-TRUEAluJbSINE,Alu
chr1193054575CG0.00029TROVE2+FALSE(ATTTT)nSINE,Alu
chr128661656AG0.00319MED18+TRUEAluSgSINE,Alu
chr136068281TC0.00201PSMB2-TRUEAluScSINE,Alu
chrX77083845TC0.00102MAGT1-TRUEAluSzSINE,Alu
chr1156692052TA0.00369ISG20L2-FALSEAluYSINE,Alu
chr894744813CT5.22032E-05RBM12B-FALSE
chr231491629AG2.09863E-05.FALSE
chr286251151TC0.00882.FALSEAluSxSINE,Alu
chr2204301754CG0.00012RAPH1-FALSE
chr19331101AG0.00072H6PD+FALSEAluSxSINE,Alu
chr871550832TC0.00234LACTB2-AS1,LACTB2+,-FALSE
chr116929327CT5.08143E-05NBPF1-FALSEERVL-E-intSINE,Alu
chr2206983491TC0.00505.FALSEAluSxSINE,Alu
chr1154128837GT0.00032TPM3-FALSE
chr237328013TC0.00765.FALSE
chr4119555188CA0.00205LOC729218+FALSE
chr261764920CA0.00662XPO1-FALSE
chr1145273345TC0.00640NBPF20,NOTCH2NL+FALSE
chr1214524576TC0.00408PTPN14-TRUEAluSgSINE,Alu
chr1742880118TC0.00140GJC1-TRUEAluJbSINE,Alu
chr4153898334AG0.00662FHDC1+FALSEAluJoSINE,Alu
chr115993714TA0.00066.FALSE
chr76501833AT0.00032KDELR2-FALSE
chr116905837GA0.00029NBPF1-FALSE
chr194983203CT0.00686ABCD3+FALSE
chr1461112736TG0.00418SIX1-FALSE(T)nSINE,Alu
chr1144053662TG0.00173.FALSE
chr371005566CT0.00209FOXP1-FALSE(T)nSINE,Alu
chr2062598815CT0.00711ZNF512B-FALSE
chr1144598755GA0.00743NBPF20+FALSE
chr626411987TC0.00405BTN3A1+FALSE
chr153291434AG0.00545ZYG11B+TRUEAluJrSINE,Alu
chr19642827GA0.00985SLC25A33+FALSE
chr1100550370TA0.00743SASS6-FALSE
chr564964314TC0.00208SGTB-TRUEAluScSINE,Alu
chr1179042701AG0.00132FAM20B+TRUEAluSx1SINE,Alu
chr128661657AG0.00011MED18+TRUEAluSgSINE,Alu
chr133068435AG0.00081ZBTB8A+TRUEAluYSINE,Alu
chr165898263AG0.00767LEPR,LEPROT+FALSEMIRcSINE,Alu
chr1269237509AG1.55617E-05MDM2+TRUE
chr15102506389CT0.00153WASH3P+FALSE
chr136534934AG0.00464.FALSEAluJoSINE,Alu
chr119543456TC0.00760LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr154871709TC0.00110SSBP3-FALSE
chr629910581CA6.62336E-05.FALSE
chr224225013AG0.00103.FALSEAluSxSINE,Alu
chr299812857AG0.00040MRPL30+TRUEAluJbSINE,Alu
chr1169101270TG0.00036ATP1B1+FALSE(T)nSINE,Alu
chr116891340TA0.00440NBPF1-FALSE
chr2216300795CG0.00641.FALSE
chr1179084080TG0.00926ABL2-FALSE
chr127992799TA0.00014IFI6-FALSEFAMSINE,Alu
chr129395329GA0.00814LINC00987+FALSE
chr19160958TC3.06099E-05.FALSEAluJbSINE,Alu
chr1194863488CT0.00615ENDOD1+FALSE
chr2207942527AT0.00107KLF7-FALSE
chr174928967TG0.00921KIF1C+FALSEAluYSINE,Alu
chr4165998226TC0.00754TMEM192-TRUEAluSxSINE,Alu
chr5167898510CG0.00013WWC1+FALSE
chr1165065251AG0.00580POLA2+TRUEAluYSINE,Alu
chr1765334766TC4.45484E-05PSMD12-TRUEAluSqSINE,Alu
chr345722396AG0.00337LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr2201842323TC0.00254FAM126B-TRUEAluJbSINE,Alu
chr2242122440CA0.00354PPP1R7+FALSE
chr1158067060TA0.00114KIRREL+FALSE
chr320025677GT0.00116RAB5A,PP2D1+,-FALSE
chr5149823795AT0.00261RPS14-FALSE
chr1179326278AG0.00379SOAT1+TRUE
chr121810903AG0.00154NBPF3+FALSEL1MC4SINE,Alu
chr1450361197GT1.76251E-06ARF6+FALSE
chr635259646GC0.00808ZNF76+FALSE
chr127205871GT0.00931.FALSE
chr119542679TC1.36514E-06LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr373024350CA0.00109GXYLT2+FALSE
chr128836975AG0.00023SNHG3,RCC1+TRUEAluScSINE,Alu
chr12120899168AG6.24570E-05GATC+TRUEAluJrSINE,Alu
chr170611296AT0.00061LRRC40-FALSE
chr717384354AG0.00908AHR+TRUEAluSxSINE,Alu
chr12124146077AG1.08379E-05GTF2H3+TRUEAluSx4SINE,Alu
chr153366576AG0.00484ECHDC2-FALSEAluJbSINE,Alu
chr13416449CA0.00748MEGF6-FALSE
chr46718775GT3.33433E-09BLOC1S4+FALSE
chr116954981CA0.00876CROCCP2-FALSE
chr1154317153CT0.00567ATP8B2+FALSE
chr1155851620AG0.00066SYT11+TRUEAluSq2SINE,Alu
chr116893686GC0.00138NBPF1-FALSE
chr2204300093AC0.00105RAPH1-FALSEFLAM_CSINE,Alu
chr255462751TA0.00613RPS27A+FALSE
chr642855979AG8.12389E-06RPL7L1+TRUEAluSzSINE,Alu
chr2103333654AT0.00488MFSD9-FALSEAluYm1SINE,Alu
chr11255401GT0.00216CPSF3L-FALSE(GCAGG)nSINE,Alu
chr324163645CG1.00972E-05THRB-FALSE
chr145976723TC0.00366MMACHC,PRDX1+,-FALSE
chr1109240642AC0.00373PRPF38B+FALSE
chr189648082GA0.00074GBP4-FALSELTR2BSINE,Alu
chr112072783CA0.00914MFN2+FALSE
chr136068325TC0.00065PSMB2-TRUEAluScSINE,Alu
chr1109605647GA0.00019.FALSEAluYSINE,Alu
chr3194362721GA5.25740E-07LSG1-FALSE
chr468484330GA0.00131UBA6-FALSE
chr1745761110GT0.00816.FALSE
chr167874697TC0.00163SERBP1-TRUEAluSx3SINE,Alu
chr1610626615CT0.00489EMP2-FALSE(T)nSINE,Alu
chr21636938CT0.00072PXDN-FALSE(T)nSINE,Alu
chr1145509569AG0.00777NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr1176132119GC0.00134RFWD2-FALSEL3bSINE,Alu
chr1144868170CT0.00415NBPF20,PDE4DIP+,-FALSE
chr155316322AG0.00266DHCR24-FALSE
chr126449882AG0.00783PDIK1L+FALSE
chr2206986291TC0.00143.FALSEAluSzSINE,Alu
chr1109818270CT0.00996CELSR2+FALSE
chr12120898728AG0.00947GATC+TRUEAluYSINE,Alu
chr19160963TC0.00098.FALSEAluJbSINE,Alu
chr1773940094TC0.00557ACOX1-TRUEAluJbSINE,Alu
chr132638775AT0.00949KPNA6+FALSE(A)nSINE,Alu
chr1144931727GA4.04936E-05NBPF20,PDE4DIP+,-FALSE
chr120978451TC0.00193PINK1-AS,DDOST-TRUEAluYSINE,Alu
chr1117945049GA0.00030MAN1A2+FALSE
chr313670776TC0.00336FBLN2+FALSE
chr116344402GA0.00168HSPB7-FALSEL3SINE,Alu
chr116575726TC0.00916FBXO42-FALSE
chr119586519AG0.00015MRTO4+TRUEAluSzSINE,Alu
chr121766776GC0.00343NBPF3+FALSE
chr1013320126TA0.00830PHYH-FALSE
chr153288870AG3.51337E-08ZYG11B+TRUEAluJoSINE,Alu
chr247130527GA0.00462MCFD2-FALSE
chr176229185TA0.00280ACADM+FALSE
chr199672989TC0.00044.FALSEAluSx3SINE,Alu
chr162627128AG0.00087PATJ+TRUEAluSxSINE,Alu
chr63021465TC0.00029HTATSF1P2-TRUEAluJr4SINE,Alu
chr2218571475AG0.00019PEX26+TRUEAluSzSINE,Alu
chr136068237TC0.00150PSMB2-TRUEAluScSINE,Alu
chr110519048TC0.00637.FALSEAluSx3SINE,Alu
chr425278988TC2.09007E-08PI4K2B+FALSE
chr3156259308TC0.00013SSR3-TRUEAluSq2SINE,Alu
chr136068276TC0.00110PSMB2-TRUEAluScSINE,Alu
chr3137787047CT0.00735DZIP1L-FALSE
chr1120163247TC0.00365ZNF697-FALSE
chr1911256725TC0.00096SPC24-TRUEAluJr4SINE,Alu
chr190152146CT1.61967E-05LRRC8C+FALSE
chr2120022387CT0.00728STEAP3+FALSE
chr132793185CT0.00015HDAC1+FALSE
chr5180669695TC0.00101RACK1-TRUEAluSx1SINE,Alu
chr596110544TC0.00295ERAP1-TRUE
chr187573325CT0.00121HS2ST1+FALSE(AT)nSINE,Alu
chr553840199GT0.00857SNX18+FALSE
chr540832548AT0.00048RPL37-FALSE
chr1780347528TC0.00048OGFOD3-TRUEAluJbSINE,Alu
chr1146495576GC0.00107LOC728989-FALSE
chr3188597556AG0.00309LPP+FALSE
chr110516656CT0.00808.FALSE
chr133148118AG0.00316SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr345721989AG0.00713LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr124710405AG0.00246STPG1-FALSE
chr3170113718TC0.00316SKIL+FALSE
chr145975574AG0.00050MMACHC+TRUEAluSx4SINE,Alu
chr140539208AT2.90582E-07PPT1-FALSE
chr11125525572AC0.00016CHEK1+FALSE
chr146159823TA0.00474TMEM69+FALSE
chr1186641127AT0.00546PTGS2-FALSE
chr1160967856TC0.00100F11R-TRUEAluSpSINE,Alu
chr1541590982AG0.00327OIP5-AS1+TRUEAluSx1SINE,Alu
chr128661665AG0.00808MED18+TRUEAluSgSINE,Alu
chr2204162597AG0.00296CYP20A1+TRUEAluSxSINE,Alu
chr119543457TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1114443474AG9.14620E-06AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr1327441AG1.08612E-09.FALSE
chr1958361328GC0.00972ZNF587+FALSE
chr348787684TC0.00813PRKAR2A-TRUEAluSpSINE,Alu
chr237330146CG2.68632E-05.FALSE
chr830536544TC5.33169E-07GSR-TRUEAluSpSINE,Alu
chr186117191TC0.00987ZNHIT6-TRUEAluSgSINE,Alu
chr736447346GA0.00419ANLN+FALSE
chr989626839TG0.00016LOC440173-FALSE
chr1148003749TC0.00114NBPF8-TRUEL1MC4SINE,Alu
chr358306686AG0.00970.FALSEAluSzSINE,Alu
chr265496075CT0.00972ACTR2+FALSE
chr2224622277TC0.00138AP1S3-TRUEAluSx1SINE,Alu
chr12124146597AG0.00121GTF2H3+TRUEAluSq2SINE,Alu
chr153289892AG0.00070ZYG11B+TRUEFRAMSINE,Alu
chr136067838TC1.55029E-07PSMB2-TRUEAluSzSINE,Alu
chr175289028GA0.00849RABEP1,NUP88+,-FALSE
chr457327092AG0.00091PAICS+TRUEAluSx1SINE,Alu

Differential Expression Gene Analysis