Dataset Overview
RBPSF3B4
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR081XRA
PlatformHiSeq
Pubmed ID32252787

SF3B4 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SF3B4
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SF3B4


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1117945049GA0.00120MAN1A2+FALSE
chr5121362874AG0.00022SRFBP1+TRUEFRAMSINE,Alu
chr194335335GT0.00425DNTTIP2-FALSE
chr627327349CG0.00359ZNF204P-FALSE
chr9131457814GA0.00021SET+FALSE
chr11595006TC0.00156CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr914921850AG0.00112.FALSE
chr9102744698GT0.00301ERP44-FALSE
chr119953120GA0.00027MINOS1,MINOS1-NBL1+FALSE
chr1144931727GA0.00521NBPF20,PDE4DIP+,-FALSE
chr119543456TC0.00451LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr5122359499CA0.00304PPIC-FALSE(AC)nSINE,Alu
chr16283430TC0.00751ICMT-TRUEAluSx3SINE,Alu
chr110521172TC1.01590E-06DFFA-TRUEAluYSINE,Alu
chr1109240642AC0.00373PRPF38B+FALSE
chr136690599AG0.00406THRAP3+FALSE
chr652226984GA0.00127PAQR8+FALSE(GCTCGG)nSINE,Alu
chr1153587256AT0.00013S100A14-FALSE
chr5180262080AG0.00259LINC00847+TRUEMLT2B3SINE,Alu
chr1132125961CT0.00118RCN1+FALSE
chr12124146094AG2.86040E-06GTF2H3+TRUEAluSx4SINE,Alu
chr13697486CG0.00110LRRC47-FALSEAluScSINE,Alu
chr193617403TG0.00053TMED5-FALSE
chr153288862AG0.00155ZYG11B+TRUEAluJoSINE,Alu
chr44864940CT0.00247MSX1+FALSE
chr136068295TC2.11660E-05PSMB2-TRUEAluScSINE,Alu
chr124288530AT0.00915PNRC2+FALSE
chr110520067TC2.08449E-05.FALSEAluSxSINE,Alu
chr128661657AG0.00910MED18+TRUEAluSgSINE,Alu
chr352567617AG0.00025NT5DC2-FALSEG-richSINE,Alu
chr178414329GA0.00635FUBP1-FALSEA-richSINE,Alu
chr579923843TC0.00229DHFR-TRUEAluSpSINE,Alu
chr1591044379TG0.00440IQGAP1+FALSE
chr8100890376GT0.00920COX6C-FALSE
chr237330576TC0.00055.FALSEAluSq2SINE,Alu
chr1190234133AC5.13910E-06BRINP3-FALSE
chr120977380TC0.00695PINK1,PINK1-AS+,-FALSE
chr126755643AG0.00068LIN28A+FALSEAluScSINE,Alu
chr1143189486AG0.00122LOC102723769-FALSE
chr674346347AG4.16931E-07SLC17A5-FALSE
chr1144868170CT0.00750NBPF20,PDE4DIP+,-FALSE
chr16282237TC0.00395ICMT-TRUEAluSzSINE,Alu
chr1144595935GA0.00837NBPF20+FALSEAluJbSINE,Alu
chr1949608GA0.00435ISG15+FALSE
chr132373437GA3.32434E-12PTP4A2-FALSE
chr378646942TG0.00093ROBO1-FALSE
chr46304286CT0.00054WFS1+FALSE
chr1117529752CA0.00024PTGFRN+FALSE
chr366024384GC0.00096MAGI1-FALSE
chr4155456608AG0.00734PLRG1-FALSEL1MC5SINE,Alu
chr1168523337TC0.00016CPT1A-TRUEAluSqSINE,Alu
chr63022725TC0.00081HTATSF1P2-TRUEAluSzSINE,Alu
chr679595097AG0.00712IRAK1BP1+FALSE
chr457326159AG0.00019PAICS+TRUEAluJrSINE,Alu
chr132953296AG5.26589E-05ZBTB8B+TRUEAluSzSINE,Alu
chr119542415TC0.00204LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr310192642AG0.00217VHL+TRUEAluSx1SINE,Alu
chr4170037423GT0.00802SH3RF1-FALSE
chr237327662TC0.00220.FALSE
chr237333924TC0.00298EIF2AK2-FALSEAluSzSINE,Alu
chr473923043TC0.00236COX18-TRUEAluSzSINE,Alu
chr812880381AG0.00031KIAA1456+TRUEAluJoSINE,Alu
chr133145959TG0.00755SYNC,RBBP4+,-FALSE(T)nSINE,Alu
chr315114306TC0.00036RBSN-TRUEAluYSINE,Alu
chr5140751128CG0.00647PCDHGA1,PCDHGA2,PCDHGA3,PCDHGB1,PCDHGA4,PCDHGB2,PCDHGA5,PCDHGB3+FALSE
chr1772206017TA6.66319E-05RPL38+FALSE
chr19162362TC0.00526.FALSEAluSxSINE,Alu
chr110519932TC0.00547.FALSEAluJrSINE,Alu
chr416258050CT0.00617TAPT1-AS1+FALSE
chr153291420AG6.80791E-05ZYG11B+TRUEAluJrSINE,Alu
chr4119553307TC0.00096LOC729218+FALSE
chr12326812AG0.00709RER1+FALSE
chr1116239368GA5.97604E-05VANGL1+FALSE
chr1541590982AG0.00327OIP5-AS1+TRUEAluSx1SINE,Alu
chr299812988AG0.00700MRPL30+TRUEAluJbSINE,Alu
chr1958357211AG0.00041ZNF587B+TRUEAluSx3SINE,Alu
chr132158374TC0.00134COL16A1-FALSE
chr135647099AG0.00092SFPQ-FALSE
chr9132575836AC0.00546TOR1A-FALSE
chr132631809CT2.91083E-08KPNA6+FALSE
chr1109475572AG0.00096GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr1145369706TC0.00186NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr7137612915GA0.00057CREB3L2-FALSE
chr138155699TG0.00734C1orf109-FALSEAluSx1SINE,Alu
chr12124069108GA0.00635TMED2+FALSE(GCG)nSINE,Alu
chr9135172412AG0.00394SETX-FALSE
chr2128602913GA0.00230.FALSE
chr574072648TA0.00036NSA2+FALSE
chr19163319TC0.00936.FALSEAluSpSINE,Alu
chr128859267AC2.52971E-07RCC1+FALSE
chr116133978TC0.00515UQCRHL-FALSE
chr1148577409CA0.00897NBPF15+FALSE
chr119984346AG0.00071MINOS1-NBL1,NBL1+FALSE
chr1150704633TC1.58455E-05CTSS-TRUEAluJoSINE,Alu
chr2174090331AC0.00901ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr413601337GA7.28365E-09BOD1L1-FALSE
chr4153898316AG0.00312FHDC1+TRUEAluJoSINE,Alu
chr596366330GC0.00251.FALSE(TG)nSINE,Alu
chr1079800443AG0.00971RPS24+FALSE
chr153291395AG0.00323ZYG11B+TRUEAluJrSINE,Alu
chr735840866AG0.00947SEPT7+FALSE
chr1111721354GT0.00616CEPT1+FALSE
chr237328013TC1.05952E-05.FALSE
chr372426071TA0.00169RYBP-FALSE(T)nSINE,Alu
chr3100083425GA0.00717TOMM70-FALSEFAMSINE,Alu
chr1204525548AG0.00027MDM4+TRUEAluSzSINE,Alu
chr1138156GT0.00048LOC729737-FALSE
chr116933110TC0.00143NBPF1-FALSEL1MC2SINE,Alu
chr729962586GA0.00051SCRN1-FALSE
chr1160967848TC0.00200F11R-TRUEAluSpSINE,Alu
chr642856064AG0.00019RPL7L1+TRUEAluSzSINE,Alu
chr76501832AC0.00175KDELR2-FALSE
chr2217366971AG0.00616.FALSEAluSz6SINE,Alu
chr11255402CG0.00333CPSF3L-FALSE(GCAGG)nSINE,Alu
chr1207943188AG0.00263CD46+TRUEAluSx1SINE,Alu
chr1184661933GA0.00138EDEM3-FALSE
chr840011786CA0.00196C8orf4+FALSE
chr116958047CT2.98219E-05.FALSE
chr4165998078TC0.00567TMEM192-TRUEAluSxSINE,Alu
chr1148189152AC0.00050PTPRJ+FALSE
chr131192650TG0.00727MATN1,MATN1-AS1+,-FALSE
chr2198368110CA0.00053HSPE1,HSPE1-MOB4+FALSE
chr5177658896AC0.00642PHYKPL-FALSE
chr12133298254AG0.00849PGAM5+TRUEAluSpSINE,Alu
chr2112252464GA2.95640E-06MIR4435-2HG-FALSE
chr1765334802TC1.10547E-05PSMD12-TRUEAluSqSINE,Alu
chr146075719AG0.00461NASP+TRUEAluSx4SINE,Alu
chr7102016321CT0.00201LOC100289561,LOC100630923+FALSE
chr128661576AG0.00939MED18+TRUEAluSgSINE,Alu
chr1185069561AG0.00675RNF2+FALSE
chr1959095456AG0.00125CENPBD1P1+TRUEAluJbSINE,Alu
chr1172547465AG0.00725SUCO+FALSE
chr237329369TC0.00010.FALSEAluJr4SINE,Alu
chr1100490067AG0.00267SLC35A3+TRUEAluSgSINE,Alu
chr1326499AG0.00583.FALSE
chr74809089AG0.00552FOXK1+TRUEAluSx1SINE,Alu
chr9140709880CT0.00178EHMT1+FALSE
chr1958375157AG0.00408ZNF587+TRUEAluSx4SINE,Alu
chr210270757AT0.00382RRM2+FALSE
chr110520378TC0.00145.FALSEAluSx1SINE,Alu
chr1145209366AG0.00499NBPF20,NOTCH2NL+FALSE
chr2178186556GA0.00917LOC100130691-FALSE
chr2203742141TC0.00044.FALSEAluJbSINE,Alu
chr210586899GA0.00312ODC1,SNORA80B-FALSE
chr110093749TC0.00521UBE4B+FALSE
chr1109239335GT0.00011PRPF38B+FALSE
chr16582527TC0.00139NOL9-TRUEAluSx1SINE,Alu
chr1954971229TC0.00202LENG8+FALSE
chr128826085AG0.00153PHACTR4+TRUEAluJbSINE,Alu
chr15102516561TC0.00805WASH3P+FALSE
chr116891340TA0.00022NBPF1-FALSE
chr315838717AC0.00673ANKRD28-FALSE(A)nSINE,Alu
chr299812289AG0.00282MRPL30+TRUEAluSxSINE,Alu
chr3195243003AC0.00301PPP1R2-FALSE
chr19163334TC0.00074.FALSEAluSpSINE,Alu
chr227293351CT0.00314AGBL5,OST4+,-FALSE
chr1161559407AG0.00237FCGR2C+FALSE
chr127992825GA0.00012IFI6-FALSE
chr117735300CA0.00128RCC2-FALSE
chr153291420AG0.00069ZYG11B+TRUEAluJrSINE,Alu
chr1583685469TC0.00976BTBD1-FALSE
chr1114438951AG0.00017AP4B1-AS1,AP4B1+,-FALSE
chr131905889AG0.00565SERINC2+FALSE
chr717384393AG1.74996E-06AHR+TRUEAluSxSINE,Alu
chr1668962CT0.00852.FALSE
chr417803568TC0.00044DCAF16-TRUEAluYSINE,Alu
chr120826788AT6.12716E-05MUL1-FALSE
chr1541573612CA0.00355CHP1+FALSE
chr136067838TC0.00348PSMB2-TRUEAluSzSINE,Alu
chr1156567496CT0.00012GPATCH4-FALSEMIR3SINE,Alu
chr16583383TC0.00305NOL9-TRUEAluSqSINE,Alu
chr1162354203AG0.00956C1orf226+FALSE
chr826435508CT0.00106DPYSL2+FALSE(TC)nSINE,Alu
chr7100031511CT0.00490MEPCE+FALSE
chr1779476999GT6.09622E-06ACTG1-FALSE
chr116524869TC0.00164ARHGEF19-FALSE
chr1098278593AT0.00792TM9SF3-FALSE
chr151873951GA0.00591EPS15-FALSE
chr314239845GA0.00375LSM3+FALSE
chr344791320TC0.00059KIAA1143-TRUEAluJrSINE,Alu
chr1145112414TC0.00079NBPF20,SEC22B+FALSE
chr3195451488CT1.73907E-06MUC20+FALSE
chr5178293266GA0.00924ZNF354B+FALSE
chr11252513TC0.00223CPSF3L-TRUEAluSpSINE,Alu
chr220648961TC0.00304RHOB+FALSE
chr76501828CA0.00110KDELR2-FALSE
chr154563156AG3.59804E-06TCEANC2+FALSE
chr1180247474TC0.00022.FALSE
chr410443059AT0.00187ZNF518B-FALSE
chr136068237TC0.00974PSMB2-TRUEAluScSINE,Alu
chr7116340269CT0.00313MET+FALSE
chr174721376AG0.00177PLD2+FALSE
chr1202861470CA0.00441KLHL12-FALSE
chr237331614TC0.00876.FALSEAluJbSINE,Alu
chr1958375195AG0.00080ZNF587+TRUEAluSx4SINE,Alu
chr129041856AG0.00756GMEB1+TRUEAluSq4SINE,Alu
chr3197611125AG0.00948.FALSEAluSx1SINE,Alu
chr439551975TC5.31269E-07UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr238971059AC0.00539SRSF7-FALSE
chr4129795672CA0.00284JADE1+FALSE
chr4190873405CT0.00325FRG1+FALSE
chr1109818160TG3.82986E-06CELSR2+FALSE
chr3196670087GA4.07177E-06NCBP2-AS2+FALSE
chr111347155CT0.00273UBIAD1+FALSE
chr2105881071CA0.00851TGFBRAP1-FALSE
chr3119212012AC0.00976POGLUT1+FALSE
chr1113672634AG0.00967.FALSEAluJbSINE,Alu
chr1022824831CT0.00702PIP4K2A-FALSE
chr116889985TC0.00778NBPF1-FALSE
chr224225006AG0.00555.FALSEAluSxSINE,Alu
chr2178129405CT0.00295NFE2L2-FALSE(CGG)nSINE,Alu
chr568850966GT0.00134OCLN+FALSEAluSx4SINE,Alu
chr1115259543CT0.00492CSDE1-FALSE
chr1165877666TC0.00189UCK2+FALSE(T)nSINE,Alu
chr4113346996GA0.00191ALPK1+FALSE
chr1272096335AG1.07858E-05TMEM19+FALSEAluSz6SINE,Alu
chr552393421CT0.00144MOCS2-FALSEL1MA9SINE,Alu
chr812283440AG0.00041FAM86B2-FALSE
chr174672323CA0.00616FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr2198416724AT0.00378HSPE1-MOB4,MOB4+FALSE
chr1738512480CT0.00725RARA+FALSE
chr1120612154CG0.00054NOTCH2-FALSE
chr136299630AG0.00828AGO4+FALSE
chr138279666CT0.00521MTF1-FALSE(T)nSINE,Alu
chr124862649AG0.00299RCAN3+FALSE
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr4190883001CG0.00297FRG1+FALSE
chr167874689TC7.42611E-10SERBP1-TRUEAluSx3SINE,Alu
chr110517538TC0.00840.FALSEAluSx1SINE,Alu
chr120976075TC0.00135PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr873958240GA0.00093TERF1+FALSE
chr1758024275AG0.00455RPS6KB1+FALSE
chr110521170TC0.00538DFFA-TRUEAluYSINE,Alu
chr124861704GA0.00345RCAN3+FALSE
chr4120216206CT0.00205USP53+FALSE
chr344692564CG0.00182ZNF35+FALSE
chr5175802154CT0.00883.FALSE(CATC)nSINE,Alu
chr167874696TC0.00014SERBP1-TRUEAluSx3SINE,Alu
chr457326960AG2.00220E-09PAICS+TRUEAluSx1SINE,Alu
chr136067886TC1.98907E-05PSMB2-TRUEAluSzSINE,Alu
chr237331531TC0.00389.FALSEAluJbSINE,Alu
chr12133298417AG6.66134E-16PGAM5+TRUEAluSpSINE,Alu
chr5150869672AT0.00755SLC36A1+FALSE
chr81730491AG5.38446E-06CLN8+TRUEAluSx1SINE,Alu
chr122854702CT4.66415E-11ZBTB40+FALSE
chr1110049203GC0.00209.FALSE
chr116889642TC0.00017NBPF1-TRUE
chr6159396143TC0.00185.FALSEAluScSINE,Alu
chr238971644TG0.00239SRSF7-FALSE
chr2242512159AG0.00243BOK+FALSE
chrX152916233CA0.00758DUSP9+FALSE

Differential Expression Gene Analysis