Dataset Overview
RBPAKAP1
Knock-MethodshRNA
RBP FamilyTUDOR
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR338CON
PlatformHiSeq
Pubmed ID32252787

AKAP1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of AKAP1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of AKAP1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr119934839AG0.00052MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1075008815TC5.77576E-09DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr764441632AT0.00038ZNF117-FALSE
chr237327670TC0.00021.FALSE
chr116889624TC0.00614NBPF1-TRUE
chr11653093AG0.00642CDK11B,CDK11A-FALSEL2SINE,Alu
chr1226923264GA0.00046ITPKB-FALSE
chr3156258230TC0.00176SSR3-TRUEAluYk3SINE,Alu
chr1148004548TC0.00220NBPF8-FALSE
chr13548832GC0.00464WRAP73-FALSE
chr154691910AG0.00481SSBP3-FALSE
chr45710647AG5.78692E-06EVC2-FALSE
chr168943486CT0.00079DEPDC1-FALSE(TTCTCTT)nSINE,Alu
chr1749042216TC0.00746SPAG9-TRUEAluJbSINE,Alu
chr7128143932AG0.00332.FALSEAluSq2SINE,Alu
chr237330611TC0.00835.FALSEAluSq2SINE,Alu
chr1205687358TC0.00432NUCKS1-FALSE(T)nSINE,Alu
chr220449605CT0.00871PUM2-FALSE
chr1235392546TC0.00312ARID4B-FALSE
chr1203277242TC0.00023BTG2+FALSE
chr1148023637CT0.00014NBPF8-FALSE
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr613790848TC0.00344MCUR1-TRUEAluSx1SINE,Alu
chr310028294GA1.35555E-07EMC3-FALSE
chr11655474GA0.00694CDK11B,CDK11A-FALSE
chr116892256TC0.00468NBPF1-FALSE
chr2206983298TC0.00811.FALSEAluJbSINE,Alu
chr11570928GT0.00173CDK11B-FALSE
chr2204301753TA0.00012RAPH1-FALSE
chr63021448TC0.00126HTATSF1P2-TRUEAluJr4SINE,Alu
chr631110789TC0.00798.FALSE
chr3195242996CA0.00136PPP1R2-FALSE
chr6158505088AG0.00083SYNJ2+FALSE
chr3196080624TC0.00795UBXN7-TRUEAluSxSINE,Alu
chr1145513016AG0.00069NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1240255561GA0.00224FMN2+FALSE(GGC)nSINE,Alu
chr1145511988AG0.00131NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1143399181TG0.00832.FALSE
chr1911257673TC0.00155SPC24-TRUEAluSpSINE,Alu
chr1475202857AG2.23354E-05FCF1+TRUEAluSxSINE,Alu
chr439550558TC0.00441UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1145293469GC0.00578NBPF20,NBPF10+FALSE
chr1156878044GA9.48586E-05PEAR1+FALSE
chr8101269589AT0.00281RNF19A-FALSE
chr2113494520TC0.00267CKAP2L-FALSEAluSx1SINE,Alu
chr110520076TC0.00075.FALSEAluSxSINE,Alu
chr2134728068AG0.00188IFNAR1+TRUEAluScSINE,Alu
chr11209196CG0.00581UBE2J2-FALSE(CCG)nSINE,Alu
chr19162394TC0.00072.FALSEAluSxSINE,Alu
chr366430375TA0.00091LRIG1-FALSE
chr126144435CG0.00131SEPN1+FALSE
chr8128752685GA0.00000MYC+FALSE
chr3139086995CA0.00743COPB2-FALSE
chr2128064423CT0.00063MAP3K2-FALSE
chr4152583924AT0.00284FAM160A1+FALSE
chr1347345467GT0.00495ESD-FALSE
chr1153617980AG8.13079E-05CHTOP+FALSE
chr153679610GA0.00084CPT2+FALSEAluSzSINE,Alu
chr19160900TC0.00893.FALSEAluJbSINE,Alu
chr133149376AG0.00357SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr4113198883GT0.00905TIFA-FALSE
chr175671215CT0.00019SLC44A5-FALSE
chr6149912307AG0.00026.FALSEAluScSINE,Alu
chr1115275398TG0.00474CSDE1-FALSE
chr128661576AG0.00939MED18+TRUEAluSgSINE,Alu
chr1116235186AG0.00054VANGL1+FALSE
chr1145688956AG0.00155NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr143629982CT0.00733EBNA1BP2-FALSE
chr1248539888CA0.00088PFKM+FALSE
chr275882576TC0.00328MRPL19+FALSE
chr145975269AG0.00098MMACHC+TRUEAluSg7SINE,Alu
chr186049364AG0.00207CYR61+FALSE
chr116890500GA0.00030NBPF1-FALSE
chr286731290TC0.00149CHMP3,RNF103-CHMP3-FALSEL1MC1SINE,Alu
chr1051374391CG0.00028TIMM23B+FALSE
chr1542503333TC0.00120TMEM87A-FALSE(T)nSINE,Alu
chr4189026673AG0.00994TRIML2-FALSE
chr138463504CT0.00068FHL3-FALSE
chr1900717CT0.00661KLHL17+FALSE(TTTA)nSINE,Alu
chr484215880TC4.10546E-05HPSE-TRUEAluJrSINE,Alu
chr16282237TC0.00771ICMT-TRUEAluSzSINE,Alu
chr1183596136AG0.00123ARPC5-FALSE
chr165297860AT0.00847RAVER2+FALSE
chr285773376TC0.00607GGCX-TRUEAluYSINE,Alu
chr1680636808CT0.00881CDYL2-FALSE
chr894935937TC0.00338PDP1+FALSE
chr1761502463TG0.00370TANC2+FALSE
chr1939433138GA0.00276FBXO17-FALSEAluJbSINE,Alu
chr146075779AG0.00640NASP+TRUEAluSx4SINE,Alu
chr144071221GA0.00105PTPRF+FALSE
chr116913677TC0.00165NBPF1-FALSE
chr521883662TG0.00108CDH12-FALSE
chr17827697GC0.00760CAMTA1+FALSE
chr7131241085GA0.00600PODXL-FALSE(GCA)nSINE,Alu
chr2025427801AG0.00300GINS1+TRUEAluSzSINE,Alu
chr1749042381TC0.00931SPAG9-TRUEAluJbSINE,Alu
chr131905906TA0.00092SERINC2+FALSE
chr1220231959TC0.00464RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr146075192AC0.00045NASP+FALSEA-richSINE,Alu
chr611185161CT0.00297NEDD9-FALSE
chr110517672TC0.00090.FALSEAluSx1SINE,Alu
chr1155695968AG0.00439DAP3+TRUEAluSpSINE,Alu
chr3183476685GA0.00032YEATS2+FALSE
chr1946052996TC2.38036E-05OPA3-TRUEAluSz6SINE,Alu
chr613790964TC5.10728E-05MCUR1-TRUEAluSx1SINE,Alu
chr117298140CG0.00584CROCC+FALSE
chr128826128AG0.00483PHACTR4+TRUEAluJbSINE,Alu
chr1109856378CA0.00804SORT1-FALSE
chr765618249AG0.00785CRCP+TRUEAluSpSINE,Alu
chr11595078TC0.00714CDK11B,SLC35E2B-FALSEAluSgSINE,Alu
chr194995411CA0.00849F3-FALSEAluSxSINE,Alu
chrX123047168AG2.82326E-05XIAP+TRUEAluSxSINE,Alu
chr111083395CT0.00616TARDBP+FALSE
chr115993013GA1.16652E-10.FALSE
chr116112795AG1.78234E-05FBLIM1+FALSE
chr232535568AG0.00192.FALSEMER8SINE,Alu
chr1179829584TC0.00204TOR1AIP2-TRUEAluJrSINE,Alu
chr153291382AG0.00114ZYG11B+TRUEAluJrSINE,Alu
chr398620372GA3.94317E-05DCBLD2-FALSE
chr315113656TC1.73787E-06RBSN-TRUEAluSz6SINE,Alu
chr146828734TC0.00604NSUN4+FALSE
chr1453243438TC7.89901E-12GNPNAT1-TRUEAluSx3SINE,Alu
chr16583270CG0.00529NOL9-FALSE
chr1153617980AG0.00272CHTOP+FALSE
chr342591956GA0.00503SEC22C-FALSE
chr136770605CT0.00971THRAP3+FALSE(T)nSINE,Alu
chr136067677TC0.00462PSMB2-TRUEAluSzSINE,Alu
chr128661767AG0.00242MED18+TRUEAluSgSINE,Alu
chr1175914284AG0.00036RFWD2-FALSE
chr314986200GT0.00346FGD5-AS1-FALSEAluSq2SINE,Alu
chr238971639AT0.00019SRSF7-FALSE
chr1115249239GA0.00034NRAS-FALSE
chr111810674GA0.00279AGTRAP+FALSE
chr11597356GC0.00995CDK11B,SLC35E2B-FALSE
chr211318235GC0.00911PQLC3+FALSE
chr1256215102TA0.00405DNAJC14-FALSE
chr1075008815TC0.00309DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr627425185CA0.00577ZNF184-FALSE
chr12125513788AG0.00592.FALSEAluSx1SINE,Alu
chr6134492485CT0.00245SGK1-FALSE
chr453463566CT5.12751E-05USP46-FALSE
chr11594196TC0.00097CDK11B,SLC35E2B-FALSE
chr3122283290GC0.00029DTX3L,PARP9+,-FALSE
chr187213174TG0.00081SH3GLB1+FALSE
chr116889620TC0.00884NBPF1-FALSE
chr116529016CT0.00024ARHGEF19-FALSE
chr1269237077AG0.00445MDM2+TRUE(GA)nSINE,Alu
chr644222156AT0.00856SLC35B2-FALSE
chr1153963246GA6.32081E-05RPS27+FALSE
chr29629953CA0.00042ADAM17-FALSE
chr2206986233TC0.00545.FALSEAluSzSINE,Alu
chr1156567496CT0.00012GPATCH4-FALSEMIR3SINE,Alu
chr19328092AG0.00058H6PD+TRUEAluJrSINE,Alu
chr6166824702CT0.00587RPS6KA2-FALSE(T)nSINE,Alu
chr133148789AG0.00568SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1145693061AG0.00158NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr237331065TC0.00293.FALSEAluSx1SINE,Alu
chr237331025TC0.00055.FALSEAluSx1SINE,Alu
chrX3526658AT0.00152PRKX-FALSE(AC)nSINE,Alu
chr642060429TC0.00017.FALSEAluSz6SINE,Alu
chr1225977968CT0.00490SRP9+FALSE
chr3160213317TA0.00208KPNA4-FALSE
chr3196557274CT0.00285PAK2+FALSE
chr267631831GA0.00423ETAA1+FALSE
chr1117618067CT0.00118TTF2+FALSE
chr1179072966CT0.00107ABL2-FALSEMIRcSINE,Alu
chr1204526795AG0.00199MDM4+TRUEAluSxSINE,Alu
chr3195412864GA0.00725SDHAP2+FALSE
chr1179041705AT0.00068FAM20B+FALSE
chr137949806GA2.03247E-05ZC3H12A+FALSE
chr2161130868AC0.00297RBMS1-FALSE
chr2174773510TA0.00775SP3-FALSEA-richSINE,Alu
chr239212563GT9.15843E-06SOS1-FALSE
chr1269237509AG1.55617E-05MDM2+TRUE
chr642857057AG0.00020RPL7L1+TRUEAluSpSINE,Alu
chr536143392CT0.00625LMBRD2-FALSE
chr1145688664AT0.00679NBPF20,NBPF10,RNF115+FALSE
chr1151668295AC0.00576SNX27+FALSE
chr256150885GA0.00624EFEMP1-FALSE
chr152381348TG0.00500RAB3B-FALSE
chr1112003957GA0.01000ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr348485381TC0.00103TMA7+FALSE
chr1204189357CT0.00835PLEKHA6-FALSE
chr799636950AG0.00927ZKSCAN1+FALSEAluSx1SINE,Alu
chr116932428CG0.00620NBPF1-FALSEL1MC2SINE,Alu
chr47761114GA8.00249E-13AFAP1,AFAP1-AS1+,-FALSE
chr1161088583TG0.00822NIT1+FALSE
chr1098281480TA0.00620TM9SF3-FALSE
chr16583474TC0.00438NOL9-TRUEAluSqSINE,Alu
chr2203744658TC0.00112.FALSEAluSx1SINE,Alu
chr187811249TA0.00653LMO4+FALSE
chr444176960TC0.00043KCTD8-FALSE
chr2054963816TC0.00750AURKA-TRUEAluSq10SINE,Alu
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr1114306369AT0.00352RSBN1-FALSE
chr1757279258AG0.00095PRR11+TRUEAluSq2SINE,Alu
chr261416403TG0.00350USP34-FALSEAluSc8SINE,Alu
chr2035520935TC0.00120TLDC2,SAMHD1+,-FALSEFLAM_ASINE,Alu
chr19161668TC0.00456.FALSE
chr4177252238AG9.63526E-05SPCS3+TRUE
chr1610626615CT0.00489EMP2-FALSE(T)nSINE,Alu
chr131905884GA2.48126E-05SERINC2+FALSE
chr64995431CT0.00449RPP40-FALSE
chr110517635TC0.00553.FALSEAluSx1SINE,Alu
chr115896984AG0.00297DNAJC16+FALSEFLAM_CSINE,Alu
chr123885230CG0.00075ID3-FALSE
chr128564195TC0.00113ATPIF1+FALSE
chr9139698779CG0.00106CCDC183,CCDC183-AS1+,-FALSEL2bSINE,Alu
chr117199303GA0.00062LOC440570+FALSE
chr1779529443TC0.00153NPLOC4-TRUEAluSx1SINE,Alu
chr722765456GT5.19964E-05LOC541472-FALSE
chr314986111TC0.00653FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1765334967TC0.00045PSMD12-TRUEAluSqSINE,Alu
chr19353122CG0.00562SPSB1+FALSE(GCG)nSINE,Alu
chr2232319529TA1.32288E-06NCL-FALSE
chr11152601AG0.00075SDF4-FALSE
chr340503557TC0.00487RPL14+FALSE
chr417804785TC0.00083DCAF16-TRUEAluSxSINE,Alu
chr1689623619AG0.00275SPG7+FALSE
chr5112312528TC0.00827DCP2+FALSE
chr176227022AG0.00035ACADM+FALSE
chr4129924977CA0.00760SCLT1-FALSE
chr1065382718GA0.00984REEP3+FALSEAluScSINE,Alu
chr1153507176CT0.00957S100A6-FALSE
chr576371820AG0.00162.FALSE
chr1101354038TC0.00565EXTL2-TRUEL1MB2SINE,Alu
chr1013320236CT0.00011PHYH-FALSE
chr115736752GA0.00170EFHD2+FALSE
chr1148003749TC0.00114NBPF8-TRUEL1MC4SINE,Alu
chr1913884422AG0.00878MRI1+TRUEAluJrSINE,Alu
chr111721832CG0.00514FBXO44+FALSE
chr187209658GA0.00219SH3GLB1+FALSE
chr1153507108AG2.72071E-06S100A6-FALSE
chr653363497AG0.00106GCLC-FALSE
chr110221302GA0.00119UBE4B+FALSE
chr315114493TC2.42944E-10RBSN-TRUEAluYSINE,Alu
chr110518826TC0.00292.FALSEAluSx1SINE,Alu
chr271412707GA0.00305PAIP2B-FALSEAluJrSINE,Alu
chr136067838TC0.00081PSMB2-TRUEAluSzSINE,Alu
chr1109475543AG0.00325GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr110368092AC0.00945KIF1B+FALSE
chr1610623576TC0.00013EMP2-TRUEAluSpSINE,Alu
chr439552066TC0.00370UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr5131804838AG0.00036C5orf56+TRUEMLT1DSINE,Alu
chr1450792961GA0.00547.FALSEAluSxSINE,Alu
chr1145509570AG0.00306NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr1179042482AG0.00079FAM20B+TRUEAluSx1SINE,Alu
chr9136209398GA0.00150MED22-FALSE
chr1256510698CG0.00944RPL41+FALSE
chr3179306775CT7.88487E-06MRPL47-FALSE
chr1945406537TC0.00278TOMM40+FALSE
chr476568481AT0.00744G3BP2-FALSE(TA)nSINE,Alu
chr136388202TG0.00707AGO1+FALSE(GCCT)nSINE,Alu
chr1153520954CT0.00910LOC101928034,S100A3+,-FALSE
chr5149823791GT0.00480.FALSE
chr154691921GA0.00909SSBP3-FALSE
chr825272423GT0.00659DOCK5+FALSE
chr2206987635TC0.00930.FALSEAluJbSINE,Alu
chr1533064461CT0.00653FMN1-FALSE
chr629910557TA0.00196.FALSE
chr27036682AT0.00335RSAD2+FALSE
chr138174665GA0.00339CDCA8+FALSE
chr3179042910AG0.00860ZNF639+TRUEAluSpSINE,Alu
chr237518045GC0.00342PRKD3-FALSE
chr237327666TC0.00028.FALSE
chr1533064465CG0.00735FMN1-FALSE
chr35258985TC0.00436EDEM1+FALSE
chr1167759573TC0.00895MPZL1+FALSE
chr484525986GT0.00081GPAT3+FALSE(TTGTT)nSINE,Alu
chr285546320GT0.00749TGOLN2-FALSEAluScSINE,Alu
chr153359182AG0.00321ZYG11A+TRUEAluSxSINE,Alu
chr224225177AG0.00375.FALSEAluSxSINE,Alu
chrX77083915TC0.00075MAGT1-TRUEAluSzSINE,Alu
chr1144931101GA0.00358NBPF20,PDE4DIP+,-FALSE
chr1666923393AG0.00228PDP2+TRUEAluSzSINE,Alu
chr136068364TC9.25575E-05PSMB2-TRUEAluScSINE,Alu
chr119934900GA0.00605MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr133149333AG0.00980SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr310192747AG0.00065VHL+TRUEAluSx1SINE,Alu
chr1272096206AG2.06003E-07TMEM19+TRUEAluSz6SINE,Alu
chr1717425631CT0.00036PEMT-FALSE
chr23609064GA0.00194RNASEH1-AS1+FALSEMER33SINE,Alu
chr1541593269AG0.00196.FALSEAluSz6SINE,Alu
chr674133914TC0.00014.FALSEAluYSINE,Alu
chr119953120GA0.00212MINOS1,MINOS1-NBL1+FALSE
chr1648386354AG0.00064LONP2,MIR5095+TRUEAluSz6SINE,Alu
chr765618876AG0.00817CRCP+TRUEAluSx3SINE,Alu
chr439551008TC0.00017UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr158999651TG0.00980OMA1-FALSE
chr35258985TC1.48069E-09EDEM1+FALSE
chr1194801640AC0.00790SRSF8+FALSE
chr791742141TC0.00100CYP51A1-FALSEAluSx3SINE,Alu
chr532404176CT0.00342ZFR-FALSE
chr131732601AT0.00175SNRNP40-FALSE
chr1148561089TC0.00010NBPF15+FALSE
chr5122165503AT0.00170SNX2+FALSE(AC)nSINE,Alu
chr223926233CT0.00907KLHL29+FALSE
chr1108728562AT0.00228SLC25A24-FALSE
chr1246714587GA0.00150TFB2M-FALSE
chrX16782911AG0.00051.FALSEAluJbSINE,Alu
chr1773774199CT0.00056H3F3B-FALSE
chr151822219GA0.00325EPS15-FALSE

Differential Expression Gene Analysis