Dataset Overview
RBP
NONO
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR647NYX
Platform
HiSeq
Pubmed ID
32252787
NONO - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of NONO
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
8.64
6.33
-0.58578
0.00250
0.00778
A1CF
29.82
20.21
-0.52798
0.00032
0.00128
A2M
1827.0
916.07
-1.01629
1.24874E-09
1.71428E-08
AADAC
0.56
1.2
0.89173
0.02454
0.05384
AAK1
3.2
7.21
0.89554
8.99960E-06
5.41364E-05
AAMDC
20.94
14.07
-0.80158
0.00435
0.01256
AARS2
6.39
9.0
0.35410
0.03257
0.06820
AASDH
5.62
4.62
-0.49758
0.00388
0.01137
AATF
19.34
27.21
0.38737
0.00983
0.02503
AATK
2.13
6.31
1.87770
1.16201E-20
1.05135E-18
Showing 1 to 10 of 6,881 entries
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Function Analysis of Target Genes of NONO
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AASS
121722841_121722945_121721553_121721649_121726065_121726233
0.00169
-0.221
DataSet_01_449
View details
ADCY9
4042146_4042286_4038994_4039097_4043406_4043511
0.00560
-0.167
DataSet_01_449
View details
ADRM1
60883423_60883526_60883038_60883234_60883710_60883918
0.00912
0.031
DataSet_01_449
View details
AKR1C2
5041391_5041469_5040816_5040939_5042741_5042858
0.00087
0.038
DataSet_01_449
View details
APOA1
116707716_116707847_116706466_116707127_116708060_116708145
0.00002
-0.013
DataSet_01_449
View details
ASGR1
7080513_7080645_7080299_7080395_7081812_7082218
0.00366
-0.048
DataSet_01_449
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ATM
108158136_108158165_108154953_108155200_108158326_108158442
0.00663
0.193
DataSet_01_449
View details
BPIFB2
31596005_31596101_31595405_31595566_31596346_31596489
0.00002
-0.242
DataSet_01_449
View details
CA13
86137183_86137524_86133155_86133354_86142313_86142429
0.00700
-0.125
DataSet_01_449
View details
CD46
207963597_207963690_207958963_207959027_207966863_207968858
0.00083
0.091
DataSet_01_449
View details
Showing 1 to 10 of 59 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACLY
40068672_40068795_40069967_40070153_40066474_40066537
0.00000
0.211
DataSet_01_449
View details
ACLY
40068672_40068795_40069967_40070149_40066474_40066537
0.00001
0.159
DataSet_01_449
View details
AFMID
76200908_76200981_76202026_76202131_76187050_76187141
0.00830
0.51
DataSet_01_449
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AGMAT
15904179_15904346_15906588_15906637_15901251_15901336
0.00030
0.158
DataSet_01_449
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ANXA4
70008651_70008706_70031664_70031759_69969105_69969307
0.00001
0.18
DataSet_01_449
View details
ARL3
104459129_104459246_104465102_104465246_104449649_104449700
0.00001
0.306
DataSet_01_449
View details
ASGR2
7010318_7010470_7010549_7010636_7005408_7005515
0.00074
0.088
DataSet_01_449
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BCAS2
115118210_115118372_115119308_115119379_115113320_115113371
0.00958
-0.234
DataSet_01_449
View details
C1GALT1
7275885_7276010_7277169_7277262_7273888_7274170
0.00865
-0.477
DataSet_01_449
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CBX3
26245987_26246130_26248085_26248175_26242590_26242642
0.00080
0.205
DataSet_01_449
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Showing 1 to 10 of 103 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101576820_101576953_101576820_101576915_101577064_101577156
0.00618
-0.204
DataSet_01_449
View details
AKR1C2
5041391_5042858_5042741_5042858_5040816_5040939
0.00102
0.066
DataSet_01_449
View details
ATP5G1
46970178_46970404_46970178_46970272_46970770_46970818
0.00797
0.056
DataSet_01_449
View details
C11orf74
36616062_36616191_36616062_36616142_36631630_36631789
0.00777
-0.229
DataSet_01_449
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00560
0.054
DataSet_01_449
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CCL20
228678569_228678818_228678569_228678703_228680169_228680284
0.00028
0.027
DataSet_01_449
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DHRS2
24113617_24113763_24113617_24113704_24114035_24114091
0.00011
-0.048
DataSet_01_449
View details
HMGA1
34208513_34208692_34208513_34208659_34210488_34210572
0.00612
0.053
DataSet_01_449
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HMGA2
66221780_66221975_66221780_66221867_66232298_66232349
0.00000
-0.038
DataSet_01_449
View details
ILKAP
239098499_239098613_239098503_239098613_239096771_239096898
0.00477
0.003
DataSet_01_449
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Showing 1 to 10 of 14 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ATP6V1G2-DDX39B
31508258_31508354_31508258_31508343_31509726_31509925
0.00031
-0.679
DataSet_01_449
View details
ATP6V1G2-DDX39B
31508258_31508343_31508258_31508311_31509726_31509925
0.00046
-0.138
DataSet_01_449
View details
ATP6V1G2-DDX39B
31508258_31508354_31508258_31508311_31509726_31509925
0.00088
-0.146
DataSet_01_449
View details
BAG6
31615482_31615645_31615482_31615603_31616453_31616528
0.00015
0.112
DataSet_01_449
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BAG6
31608161_31608334_31608161_31608305_31608421_31608469
0.00985
0.315
DataSet_01_449
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CERS2
150939231_150939381_150939231_150939338_150939549_150939678
0.00658
0.019
DataSet_01_449
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LL22NC03-80A10.6
22661154_22661386_22661197_22661386_22658307_22658479
0.00977
0.191
DataSet_01_449
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POLD2
44161432_44161794_44161432_44161708_44163109_44163131
0.00570
-0.177
DataSet_01_449
View details
RALGAPA2
20517299_20517461_20517299_20517428_20527347_20527476
0.00650
0.215
DataSet_01_449
View details
RPLP0
120636704_120636803_120636704_120636796_120636920_120637008
0.00004
0.017
DataSet_01_449
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Showing 1 to 10 of 12 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ILK
6629923_6630387_6629923_6630198_6630301_6630387
0.00553
-0.026
DataSet_01_449
View details
LYPLA2
24120713_24121090_24120713_24120815_24120916_24121090
0.00198
-0.05
DataSet_01_449
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MED15
20939141_20939554_20939141_20939302_20939387_20939554
0.00985
-0.031
DataSet_01_449
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MOV10
113240908_113242432_113240908_113241100_113242306_113242432
0.00480
-0.2
DataSet_01_449
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RPL10
153626652_153626883_153626652_153626735_153626837_153626883
0.00000
-0.18
DataSet_01_449
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RPS7
3622947_3623274_3622947_3623038_3623190_3623274
0.00229
0.011
DataSet_01_449
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SOD2
160100095_160103670_160100095_160100330_160103505_160103670
0.00272
0.088
DataSet_01_449
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SSH3
67074308_67074584_67074308_67074433_67074512_67074584
0.00920
-0.215
DataSet_01_449
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TMEM59L
18728964_18729302_18728964_18729082_18729184_18729302
0.00353
-0.055
DataSet_01_449
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
6283306
T
C
0.00275
ICMT
-
TRUE
AluSx3
SINE,Alu
chr1
53289686
A
G
0.00460
ZYG11B
+
TRUE
AluSz
SINE,Alu
chr1
201845882
G
A
0.00890
IPO9
+
FALSE
chr1
151095753
A
G
0.00256
GABPB2
+
TRUE
AluSz
SINE,Alu
chr1
8931947
T
C
0.00059
ENO1
-
FALSE
chr1
17314702
C
T
0.00140
ATP13A2
-
FALSE
chr1
20982216
T
A
0.00065
DDOST
-
FALSE
chr1
16641899
C
T
0.00213
FBXO42
-
FALSE
chr1
82453022
A
G
0.00532
ADGRL2
+
FALSE
chr1
36068295
T
C
0.00057
PSMB2
-
TRUE
AluSc
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression