Dataset Overview
RBPAGO2
Knock-MethodshRNA
RBP FamilyPiwi
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR495YSS
PlatformHiSeq
Pubmed ID32252787

AGO2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of AGO2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of AGO2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr345721827CA0.00142LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr1145512081AG0.00579NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr3194998813AG0.00572ACAP2-FALSEAluSx1SINE,Alu
chr1953997266AG0.00173ZNF813+FALSEL1M3SINE,Alu
chr1776117147GA0.00606TMC6-FALSE
chr1145689717AG7.73781E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr178414329GA0.00874FUBP1-FALSEA-richSINE,Alu
chr111190646GA0.00644MTOR-FALSE
chr2127826533AG0.00104BIN1-FALSE
chr417804852TC0.00600DCAF16-TRUEAluSxSINE,Alu
chr237328097TC3.71887E-07.FALSE
chr344791355TC0.00468KIAA1143-TRUEAluJrSINE,Alu
chr1211921702TC1.94235E-05LPGAT1-FALSE
chr1144606963GT0.00337NBPF20+FALSE
chr114106404GC0.00156PRDM2+FALSE
chr476568676TA0.00051G3BP2-FALSE
chr119934930TC0.00026MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1253435627AG0.00133EIF4B+FALSE
chr124288535AT0.00271PNRC2+FALSE
chr398307696TG3.25383E-09CPOX-FALSE
chr1015120275TC0.00387ACBD7-TRUEL1PA7SINE,Alu
chr140219280TC0.00169PPIE+FALSE
chr1152552285CA0.00400LCE3D-FALSE
chr398518157AT8.60022E-05DCBLD2-FALSE
chr543377390TC0.00062CCL28-TRUEAluSzSINE,Alu
chr265539437CT0.00076SPRED2-FALSE
chr5149781426AG0.00977CD74-FALSE
chr119585493AG3.52757E-05MRTO4+TRUEAluSc8SINE,Alu
chr133148789AG0.00568SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr11594940TC0.00115CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chrX3526616GA0.00971PRKX-FALSE
chr135648712GA0.00298SFPQ-FALSE
chr1145512024AG0.00836NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr5115428334GT0.00265COMMD10+FALSE
chr2170495929TA0.00625.FALSE
chr9131812176CT0.00220MIGA2+FALSE
chr7100957851TC0.00028LOC101927746,IFT22+,-FALSEMADE1SINE,Alu
chr195362953TC0.00072CNN3-FALSE
chr4123816376AT0.00445FGF2,NUDT6+,-FALSE
chr168940885GA0.00022DEPDC1-FALSEMIRSINE,Alu
chr337366459CA2.94197E-05GOLGA4+FALSE
chr315114399TC0.00848RBSN-TRUEAluYSINE,Alu
chr1114940227TC0.00852TRIM33-FALSE(T)nSINE,Alu
chr171532815GA0.00712ZRANB2-AS1,ZRANB2+,-FALSE
chr144171144TA0.00108KDM4A-AS1,KDM4A+,-FALSE
chr1204524866AG0.00369MDM4+TRUEAluSxSINE,Alu
chr189525966TC0.00039GBP1-FALSE
chr119542401TC0.00052LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr12133298254AG1.64181E-10PGAM5+TRUEAluSpSINE,Alu
chr642856131AG0.00062RPL7L1+TRUEAluSzSINE,Alu
chr1569991TG0.00980.FALSE
chr110517527TC0.00304.FALSEAluSx1SINE,Alu
chr2201842323TC0.00591FAM126B-TRUEAluJbSINE,Alu
chr110520258TC0.00746.FALSEAluSxSINE,Alu
chr167874849TC0.00169SERBP1-TRUEAluSxSINE,Alu
chr1110201699TC0.00513GSTM4+FALSE
chr153291420AG0.00069ZYG11B+TRUEAluJrSINE,Alu
chr917829GA0.00142WASH1-FALSE
chr1179327008AG0.00168SOAT1+TRUE
chr119810693GC0.00042CAPZB-FALSE
chr2132481245TG0.00382C2orf27A+FALSE
chr110519982TC0.00417.FALSEAluJrSINE,Alu
chr339137794TC0.00240WDR48+FALSE
chr2234438139AG0.00220USP40-FALSE
chr1179044181AG1.64117E-06FAM20B+TRUEAluSxSINE,Alu
chr1116238056GA0.00014VANGL1+FALSE
chr642048297AG0.00307TAF8+TRUEAluSq2SINE,Alu
chr1144596446AG0.00124NBPF20+TRUEAluJbSINE,Alu
chr136770073AT4.33965E-05THRAP3+FALSE
chr1165179818CT0.00799FRMD8+FALSE
chr121806710TG0.00194NBPF3+FALSE
chr1155695960AG1.11424E-05DAP3+TRUEAluSpSINE,Alu
chr111347142CG0.00789UBIAD1+FALSE
chr3196080624TC0.00795UBXN7-TRUEAluSxSINE,Alu
chr735737649GA0.00566LOC101930085+FALSEAluSzSINE,Alu
chr1942375624AG0.00049.FALSEAluSxSINE,Alu
chr111722688GA0.00076FBXO44+FALSE
chr111846092GT0.00877C1orf167,MTHFR+,-FALSE
chr1900721TC0.00109KLHL17+FALSE(TTTA)nSINE,Alu
chr167874540TC0.00555SERBP1-FALSE
chr136068243TC0.00217PSMB2-TRUEAluScSINE,Alu
chr6158093827CT0.00201ZDHHC14+FALSE
chrX123046757AG0.00535XIAP+TRUEAluSzSINE,Alu
chr9140709880CT0.00178EHMT1+FALSE
chr13545194CG0.00176TPRG1L+FALSE
chr417804740TC0.00015DCAF16-TRUEAluSxSINE,Alu
chr1183515428GA0.00232SMG7+FALSE
chr4154257510AC0.00121TRIM2+FALSE(A)nSINE,Alu
chr133148706AG0.00038SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr114590GA0.00050WASH7P-FALSE
chr19163290TC0.00130.FALSEAluSpSINE,Alu
chr2201676441GA0.00140LOC101927795,BZW1+,-FALSE
chr1120839680AC0.00584FAM72B+FALSE
chr3107773064TC0.00421CD47-TRUEFLAM_ASINE,Alu
chr1165179819TC0.00038FRMD8+FALSE
chr315112398TC2.78799E-05RBSN-TRUEAluSq2SINE,Alu
chr1194863488CT0.00615ENDOD1+FALSE
chr1330780287CT0.00748KATNAL1-FALSEAluSx1SINE,Alu
chr186118417TG0.00653ZNHIT6-FALSE
chr4170037423GT0.00802SH3RF1-FALSE
chr317199207TA0.00075TBC1D5-FALSEA-richSINE,Alu
chr1788795TG0.00333LINC01128+FALSECharlie19aSINE,Alu
chr217965390TC0.00713GEN1+FALSEL1M4SINE,Alu
chr3179117128TC0.00239GNB4-TRUEAluSzSINE,Alu
chr4155457051AT0.00378PLRG1-FALSEL2d2SINE,Alu
chr1145513114AG7.84037E-06NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr110520154TC0.00021.FALSEAluSxSINE,Alu
chr264687665CA0.00976LGALSL+FALSE
chr1207942456AG0.00322CD46+TRUEAluSg4SINE,Alu
chr126603883GA0.00660CEP85+FALSE
chr165898263AG0.00767LEPR,LEPROT+FALSEMIRcSINE,Alu
chr12125512534AG0.00024.FALSE
chr330733403AT0.00110TGFBR2+FALSE(TA)nSINE,Alu
chr153291382AG0.00691ZYG11B+TRUEAluJrSINE,Alu
chr3196660344TA0.00022SENP5+FALSE
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr237518045GC0.00342PRKD3-FALSE
chr3100084432GA0.00321TOMM70-FALSE
chr1100615003GA0.00046TRMT13,LRRC39+,-FALSE
chr441956413CT0.00543TMEM33+FALSE
chr18212601CA0.00189USP14+FALSEAluSzSINE,Alu
chr13730400TC0.00018CEP104-TRUEAluSx3SINE,Alu
chr261277776AG0.00178PEX13+TRUEAluYSINE,Alu
chr1610625075TC2.22045E-15EMP2-TRUEAluSx3SINE,Alu
chr1168214098TG0.00134.FALSE
chr210711446TC0.00014NOL10-FALSEMSTASINE,Alu
chr349762662GT6.99764E-06IP6K1-FALSE
chr124175288CG0.00646FUCA1-FALSE
chr193803490TC0.00572CCDC18-AS1-FALSEAluJrSINE,Alu
chr579923793TC0.00664DHFR-TRUEAluSpSINE,Alu
chr1145376020GA0.00067NBPF20,NBPF10+FALSE
chr177257878AG0.00027KCTD11+FALSE
chr146075663AG0.00061NASP+TRUEAluSx4SINE,Alu
chr136770045TC0.00488THRAP3+FALSE
chr1586288387CT0.00809AKAP13+FALSE
chr1610623631TC1.36144E-05EMP2-TRUEAluSpSINE,Alu
chr239212563GT9.15843E-06SOS1-FALSE
chr1225706943CT0.00229ENAH-FALSE
chr4108832727TC0.00071SGMS2,LOC101929595+,-FALSE
chr140539212CA0.00380PPT1-FALSE
chr366024384GC0.00096MAGI1-FALSE
chr135650022CA0.00762SFPQ-FALSE
chr1145273345TC0.00133NBPF20,NOTCH2NL+FALSE
chr3179117242TC0.00011GNB4-TRUEAluSzSINE,Alu
chr116893822CT0.00808NBPF1-FALSE
chr152817393TC0.00139CC2D1B-TRUEAluSg4SINE,Alu
chr147184569GC0.00061EFCAB14-FALSE
chr1169293721GA0.00978NME7-FALSE
chr11111431662TA0.00204LAYN+FALSE
chr310192747AG0.00065VHL+TRUEAluSx1SINE,Alu
chr126144435CG0.00129SEPN1+FALSE
chr1244572643CA0.00681ADSS-FALSE
chr11419823AG0.00816ATAD3B+TRUEAluYk2SINE,Alu
chr185785557TA0.00141DDAH1-FALSE
chr721941586AC0.00016CDCA7L-FALSE
chr125570692CT0.00095RSRP1-FALSE
chr138326661TC0.00023INPP5B-TRUEAluJrSINE,Alu
chr5141690772CT0.00632SPRY4-FALSE
chr1184761365AG0.00758FAM129A-FALSEAluJoSINE,Alu
chr1109818158CT0.00212CELSR2+FALSE
chr12333763GA0.00867RER1+FALSE
chr11325721CT0.00471CCNL2-FALSE
chr174929004AG0.00030KIF1C+TRUEAluYSINE,Alu
chr340503555AT0.00177RPL14+FALSE
chr11768386TC0.00208PDDC1-TRUEAluScSINE,Alu
chr136522615AG0.00658.FALSEAluScSINE,Alu
chr2179368982AC0.00530MIR548N,PLEKHA3+FALSE
chr373116345TA5.66390E-05PPP4R2+FALSE
chr1958371837AG0.00329ZNF587+TRUEAluSzSINE,Alu
chr116893691CA0.00170NBPF1-FALSE
chr43242100GA0.00916HTT+FALSE
chr133149333AG0.00980SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr189271574TC0.00074PKN2+FALSE
chr1179044100AG0.00487FAM20B+TRUEAluSxSINE,Alu
chr164935146CT0.00676PPL-FALSE
chr1145513017AG0.00037NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr9125866693CT0.00255RABGAP1+FALSE
chr193603177TC0.00364MTF2+FALSE
chr1180247476TC0.00890.FALSE
chr369038160GA0.00557EOGT-FALSE
chr1132625925AG0.00845CCDC73-FALSEAluJbSINE,Alu
chr4187647832CG0.00592.FALSE
chr110093371CT0.00264UBE4B+FALSE
chr1145116325TC0.00101NBPF20,SEC22B+FALSE(TTTTGTTT)nSINE,Alu
chr116889127AG0.00213NBPF1-FALSEL1MC4SINE,Alu
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr1146495574CT0.00085LOC728989-FALSE
chr1145689611CA0.00142NBPF20,NBPF10+FALSEAluSgSINE,Alu
chr146033497TC0.00719AKR1A1+FALSEAluYk3SINE,Alu
chr145244053AG0.00562RPS8+FALSE
chr543700242AG0.00932NNT+FALSE
chr8144940327GA0.00989EPPK1-FALSE
chr237329369TC0.00010.FALSEAluJr4SINE,Alu
chr4152020781CT0.00925RPS3A+FALSE
chr7157129834CG1.26796E-05DNAJB6+FALSE
chr272403405AC0.00227EXOC6B-FALSEGA-richSINE,Alu
chr11595031TC0.00103CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr29629293TG0.00426ADAM17-FALSE(TGT)nSINE,Alu
chr121544601CT0.00196ECE1-FALSE
chr1144521102TA0.00119NBPF20+FALSE
chr7100958270TC0.00087LOC101927746,IFT22+,-FALSE
chr2102484205TA0.00434MAP4K4+FALSE
chr165692498TC0.00356AK4+FALSE(T)nSINE,Alu
chr115909744CT0.00225AGMAT-FALSE
chr110044272AG0.00737NMNAT1+TRUEAluSx1SINE,Alu
chr116892277GT0.00021NBPF1-FALSE
chr1155161736GA0.00088MUC1-FALSE
chr1179843781TC0.00888TOR1AIP2-TRUEAluJbSINE,Alu
chr717384882AG8.88136E-05AHR+TRUEAluScSINE,Alu
chr1013687171TC0.00033FRMD4A-FALSE
chr11684346GC0.00504NADK-FALSE
chr1179044252AG0.00801FAM20B+TRUEAluSxSINE,Alu
chr2231375015AT0.00990TUG1+FALSE
chr116889596TC0.00093NBPF1-TRUE
chr564023977CT0.00340SREK1IP1-FALSE(TTTTTTT)nSINE,Alu
chr145975345AG0.00129MMACHC+TRUEAluSg7SINE,Alu
chr537290323TC0.00029.FALSEAluSzSINE,Alu
chr128261662AG0.00872SMPDL3B+FALSE
chr4153701130CT2.11271E-05ARFIP1+FALSE
chr1541597437TA0.00217.FALSEAluSz6SINE,Alu
chr140975260GC0.00902EXO5+FALSE
chr613790848TC0.00344MCUR1-TRUEAluSx1SINE,Alu
chr146159823TA0.00823TMEM69+FALSE
chr568463014GT0.00011CCNB1+FALSE
chr7143003524GT3.66232E-05CASP2+FALSEAluYSINE,Alu
chr110520258TC0.00396.FALSEAluSxSINE,Alu
chr11656557TC0.00061SLC35E2-TRUEAluSzSINE,Alu
chr1117945049GA0.00030MAN1A2+FALSE
chr2206987205TC0.00039.FALSEAluSxSINE,Alu
chr16582527TC0.00139NOL9-TRUEAluSx1SINE,Alu
chr110519975TC5.61936E-05.FALSEAluJrSINE,Alu
chr120976163CT0.00174PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr2035467713GA0.00373SOGA1-FALSE
chr349053219AG1.70535E-05WDR6,DALRD3+,-FALSE
chr16653508GA0.00320KLHL21-FALSE
chr1120162587GA0.00730ZNF697-FALSE
chr119543247TC4.83051E-05LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr244459528GA0.00126PPM1B+FALSE
chr1175526481CA0.00995UVRAG+FALSE
chr127204515TC0.00337.FALSEAluSg7SINE,Alu
chr537290492TC8.25709E-07.FALSEAluSzSINE,Alu
chr6160101723TC0.00234SOD2-TRUEAluSzSINE,Alu
chr1121133770AG0.00295SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr117522430AG0.00684.FALSE
chr579923998TC0.00753DHFR-TRUEAluSpSINE,Alu
chr347554503TG0.00720ELP6-FALSEAluSxSINE,Alu
chr11252662TC0.00235CPSF3L-TRUEAluSpSINE,Alu
chr1180897569CT0.00960KIAA1614+FALSE
chr129519736TC0.00610MECR-TRUEAluJbSINE,Alu
chr1155853061AG0.00146SYT11+TRUEAluJbSINE,Alu
chr1144930596CA0.00013NBPF20,PDE4DIP+,-FALSE
chr118709315AG0.00307RPL27A+TRUEAluYk2SINE,Alu
chr647501448TC0.00017CD2AP+FALSE
chr199672981TC0.00041.FALSEAluSx3SINE,Alu
chr199672346TC0.00222.FALSEAluJrSINE,Alu
chr6116600774CG0.00180DSE,TSPYL1+,-FALSE
chr791742142CA0.00478CYP51A1-FALSEAluSx3SINE,Alu
chr4126849AG0.00018ZNF718+TRUEAluScSINE,Alu
chr317200677TG0.00371TBC1D5-FALSE
chr2206986291TC0.00143.FALSEAluSzSINE,Alu
chr143394666GA0.00224SLC2A1-FALSE
chr765619242AG0.00545CRCP+TRUEAluSz6SINE,Alu
chr1206579936AG0.00424SRGAP2+FALSE
chr147746678GC0.00328STIL-FALSE
chr4190873405CT0.00325FRG1+FALSE
chr564964627TC2.01273E-05SGTB-TRUEAluSx1SINE,Alu
chr11666834GA0.00037SLC35E2-FALSEL1MEgSINE,Alu
chr9137330714AC0.00030RXRA+FALSE
chr12133298423AG2.89213E-13PGAM5+TRUEAluSpSINE,Alu
chr1201355943CT0.00355LAD1-FALSE
chr310192798AG0.00722VHL+TRUEAluSx1SINE,Alu
chr642855256AG0.00572RPL7L1+TRUEAluSpSINE,Alu
chr285773623TC0.00203GGCX-TRUEAluSx1SINE,Alu
chr4128756704AG0.00271.FALSEAluSxSINE,Alu
chr315114398TC0.00758RBSN-TRUEAluYSINE,Alu
chr1211921702TC0.00014LPGAT1-FALSE
chr138174987TC0.00032CDCA8+FALSE
chr2217366674AG0.00889.FALSEAluSzSINE,Alu
chr1101442211TC0.00590SLC30A7+FALSE
chr765619292AG0.00189CRCP+TRUEAluSz6SINE,Alu
chr1591044387TG0.00077IQGAP1+FALSE
chr1670284570AC0.00028EXOSC6-FALSEAluSxSINE,Alu
chr1648387215AG0.00864LONP2,MIR5095+TRUEAluJbSINE,Alu
chr5125961648AG4.28370E-08PHAX+FALSEAluSz6SINE,Alu
chr153359745AG0.00129ZYG11A+TRUEAluSx4SINE,Alu
chr255516941CT0.00110CCDC88A-FALSE
chr127205359TC3.58613E-05.FALSEAluScSINE,Alu
chr1120612154CG0.00803NOTCH2-FALSE
chr128833494GA0.00901SNHG3,RCC1+FALSE
chr131345785TA0.00962SDC3-FALSE
chr194352553CT0.00136GCLM-FALSEAluSx1SINE,Alu
chr72278515TC0.00937MRM2-TRUEAluSx1SINE,Alu
chr1419684445AG0.00351DUXAP10+FALSE
chr261277775AG0.00640PEX13+TRUEAluYSINE,Alu
chr133219771GC0.00256KIAA1522+FALSE
chr11595006TC0.00156CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr3181430146CA0.00256SOX2-OT,SOX2+FALSE
chr1228880466GA0.00216RHOU+FALSE
chr1541590978AG1.05775E-06OIP5-AS1+TRUEAluSx1SINE,Alu
chr12303094TC0.00113MORN1-TRUEAluSpSINE,Alu
chr1453242859TC9.31997E-05GNPNAT1-TRUEAluJrSINE,Alu
chr1146651038TG0.00964PDIA3P1+FALSE
chr16283296TC0.00122ICMT-TRUEAluSx3SINE,Alu
chr145973928GA0.00093MMACHC+FALSE
chr1145689717AG3.41980E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr11419743AG0.00848ATAD3B+TRUEAluYk2SINE,Alu
chr177759578AG0.00404AK5+FALSE
chr1145689568AG0.00131NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr631322980CT0.00091.FALSE
chr238971642GC0.00013SRSF7-FALSE
chr534906547TC0.00051RAD1-TRUEAluJoSINE,Alu
chr1145281613CA0.00979NBPF20,NOTCH2NL+FALSE
chr3195436334AG0.00017LINC00969+TRUEAluJrSINE,Alu
chr780373463AC0.00399SEMA3C-FALSE
chr3160219095GA0.00620KPNA4-FALSEA-richSINE,Alu
chr123689522GT0.00570ZNF436-FALSE
chr116890428TA0.00233NBPF1-FALSE
chr18931947TC0.00059ENO1-FALSE
chr315113694TC0.00622RBSN-TRUEAluSz6SINE,Alu
chr1251325237AG5.73531E-05METTL7A+TRUEAluSq2SINE,Alu
chr315114759GA0.00595RBSN-FALSE
chr1919792444AG0.00686ZNF101+TRUEAluJbSINE,Alu
chr111119935GT2.46542E-05SRM-FALSE
chr145975584TC0.00327MMACHC+FALSEAluSx4SINE,Alu
chr133148214AG0.00295SYNC,RBBP4+,-FALSEAluSgSINE,Alu

Differential Expression Gene Analysis