Dataset Overview
RBPPABPC1
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR910YNJ
PlatformHiSeq
Pubmed ID32252787

PABPC1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PABPC1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PABPC1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2112252628GT7.26456E-05MIR4435-2HG-FALSE
chr11595586TC0.00108CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr187573327TC0.00571HS2ST1+FALSE(AT)nSINE,Alu
chr2128063526CA0.00759MAP3K2-FALSE
chr7100031511CT0.00490MEPCE+FALSE
chr634254565AT0.00617.FALSE(A)nSINE,Alu
chr439550739TC0.00231UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1204526713AG0.00078MDM4+TRUEAluSxSINE,Alu
chr1214524531TC0.00753PTPN14-TRUEAluSgSINE,Alu
chr1619715543TC0.00879.FALSEAluSgSINE,Alu
chr110517290TC0.00366.FALSEAluJrSINE,Alu
chr132793185CT0.00015HDAC1+FALSE
chr310028294GA1.35555E-07EMC3-FALSE
chr153289892AG0.00505ZYG11B+TRUEFRAMSINE,Alu
chr1144828707GT0.00504NBPF20,NBPF9+FALSE
chr239212567TG0.00546SOS1-FALSE
chr1921367088AG0.00018ZNF431+TRUEAluScSINE,Alu
chr67310259AG0.00092SSR1-FALSE
chr126143728CT0.00800SEPN1+FALSEAluSxSINE,Alu
chr535058804AT0.00836PRLR-FALSE
chr11594835CG0.00195CDK11B,SLC35E2B-FALSE
chr237327651TC0.00395.FALSE
chr3179506721GC0.00018USP13+FALSE
chr140147856TC0.00205HPCAL4-TRUE
chr16694574GA0.00983THAP3,DNAJC11+,-FALSE
chr19416568CT0.00061SPSB1+FALSE
chr315113885TC0.00094RBSN-TRUEAluSz6SINE,Alu
chr19162362TC0.00526.FALSEAluSxSINE,Alu
chr237334184TA0.00202EIF2AK2-FALSEAluSzSINE,Alu
chr1173387540GA0.00438RAB6A-FALSE
chr1206566948GA0.00568SRGAP2+FALSE
chr193308168TA0.00314FAM69A-FALSE
chr19160975TC0.00858.FALSEAluJbSINE,Alu
chr5130537666AG0.00329LYRM7+TRUEAluJbSINE,Alu
chr271412707GA0.00305PAIP2B-FALSEAluJrSINE,Alu
chr237331855CT0.00965.FALSEL1MC4SINE,Alu
chr123408016CA4.80633E-05KDM1A+FALSE
chr116842064AC0.00079.FALSEMER41ESINE,Alu
chr1144822294GC0.00371NBPF20,NBPF9+FALSE
chr110519148TC0.00214.FALSEAluSx3SINE,Alu
chr261705067AT0.00084.FALSE
chr136067760TC0.00032PSMB2-TRUEAluSzSINE,Alu
chr16281866AC0.00102ICMT-FALSE
chr299812857AG0.00040MRPL30+TRUEAluJbSINE,Alu
chr46689813CA0.00141.FALSEL2bSINE,Alu
chr237429626AG0.00028CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr2204162597AG0.00296CYP20A1+TRUEAluSxSINE,Alu
chr133148691AG0.00117SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr2101622889TA0.00022RPL31+FALSE
chr641900765AG0.00256BYSL+FALSE
chr579277952AC0.00041MTX3-FALSE(AC)nSINE,Alu
chr744839297AT0.00777PPIA+FALSE
chr2217366534AG0.00700.FALSEAluSzSINE,Alu
chr310192717AG3.16601E-05VHL+TRUEAluSx1SINE,Alu
chr531554098GT2.66454E-15C5orf22+FALSE
chr237328034TC0.00047.FALSE
chr63022544TC7.02821E-06HTATSF1P2-TRUEAluJrSINE,Alu
chr19990314TA0.00017LZIC-FALSE
chr6138412313AG0.00092PERP-FALSE
chr7129472356CT0.00279UBE2H-FALSE
chr145976723TC0.00366MMACHC,PRDX1+,-FALSE
chr3112320485TC0.00107LINC01279-TRUEAluJbSINE,Alu
chr1145513113AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr624720271TG0.00839.FALSE
chr2242384528GT2.14488E-07FARP2+FALSEAluJrSINE,Alu
chr2151326173AC0.00143RND3-FALSE
chr167874697TC0.00190SERBP1-TRUEAluSx3SINE,Alu
chr5121400545AT0.00740LOX-FALSE
chr136068210TC0.00178PSMB2-TRUEAluScSINE,Alu
chr116841561GA0.00025.FALSE
chr1168523055TC0.00524CPT1A-TRUEAluYSINE,Alu
chr175336210TC0.00868RPAIN,C1QBP+,-FALSE
chr1204526795AG0.00199MDM4+TRUEAluSxSINE,Alu
chr2176791183TC0.00252LNPK-TRUEMSTDSINE,Alu
chr827661037AT0.00314ESCO2+FALSEA-richSINE,Alu
chr744841489AG0.00015PPIA+TRUEAluJrSINE,Alu
chr128662157AG0.00159MED18+TRUEAluSq2SINE,Alu
chr1420923558AC0.00373APEX1+FALSE
chr1205501469AG0.00113CDK18+FALSE
chr1112266787GT0.00642FAM212B-FALSE
chr140537923GA6.08919E-05CAP1+FALSE(A)nSINE,Alu
chr261369944TC0.00024LOC339803-TRUEAluSxSINE,Alu
chr144443175AC0.00026ATP6V0B+FALSE
chr111150682CT3.65592E-05EXOSC10-FALSE
chr124296871GC0.00733.FALSEAluSgSINE,Alu
chr1231557255CG0.00056EGLN1-FALSE(GCC)nSINE,Alu
chr6160526905CA0.00268IGF2R+FALSE
chr4248713AG0.00367ZNF876P+FALSE
chr11684346GC0.00504NADK-FALSE
chr167875106CA0.00403SERBP1-FALSE(AC)nSINE,Alu
chr46710356TC0.00046MRFAP1L1-FALSE
chr19161245TC0.00429.FALSEAluSxSINE,Alu
chr1120612194CG1.19417E-05NOTCH2-FALSE(CCG)nSINE,Alu
chr119984109TG0.00872MINOS1-NBL1,NBL1+FALSE
chr16662500CG0.00235KLHL21-FALSE
chr2121979980GA0.00525TFCP2L1-FALSEL1MB8SINE,Alu
chr624720539GC0.00225.FALSE
chr1942376843AG0.00221.FALSEAluSpSINE,Alu
chr1145512024AG0.00392NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr4129795663TA0.00165JADE1+FALSE
chr131905886CA0.00226SERINC2+FALSE
chr237429626AG0.00385CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr274375276AC0.00328BOLA3-AS1+FALSE
chr133086812TC0.00250.FALSEAluYSINE,Alu
chr2018468511TC0.00129RBBP9-TRUEAluSz6SINE,Alu
chr19328092AG0.00058H6PD+TRUEAluJrSINE,Alu
chr3196659884GT0.00217SENP5+FALSE
chr193827995CT0.00714DR1+FALSE
chr220401859AT0.00930SDC1-FALSE(A)nSINE,Alu
chr1269237053AG0.00331MDM2+TRUE
chr286252222TC0.00468POLR1A-TRUEAluSq2SINE,Alu
chr1773886219TC8.52474E-05TRIM65-TRUEFRAMSINE,Alu
chr1583659311CT0.00858FAM103A1,C15orf40+,-FALSE
chr3100083460GA0.00041TOMM70-FALSEFAMSINE,Alu
chr146782446AG0.00145UQCRH+FALSE
chr211966317TC0.00011LPIN1+FALSE
chr1251324122AG0.00226METTL7A+TRUEAluSq2SINE,Alu
chr11111431662TA0.00204LAYN+FALSE
chr4107246251GT3.16074E-09AIMP1+FALSE
chr1298942885AG1.31269E-05TMPO+TRUEAluScSINE,Alu
chr13548832GC0.00051WRAP73-FALSE
chr5139931628AC0.00804SRA1-FALSE
chr145976723TC0.00733MMACHC,PRDX1+,-FALSE
chr2216225584GT0.00848FN1-FALSE
chr127202963CT0.00106.FALSEAluSq2SINE,Alu
chr128920925AG0.00294RAB42+TRUEAluSxSINE,Alu
chr1144595935GA0.00636NBPF20+FALSEAluJbSINE,Alu
chr119542250TC0.00015LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr261276750AG0.00231PEX13+TRUEAluSpSINE,Alu
chr3195411498GA0.00722SDHAP2+FALSE
chr46718811AG1.36854E-07BLOC1S4+FALSEFLAM_ASINE,Alu
chr3196293764GC0.00392WDR53-FALSE
chr189477559CT0.00044GBP3-FALSE
chr127248275CT0.00047NUDC+FALSE
chr136068364TC9.25575E-05PSMB2-TRUEAluScSINE,Alu
chr119542401TC0.00010LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr133149486AG0.00528SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr6160113872AG0.00863SOD2-FALSE
chr417802819TC0.00112DCAF16-TRUEAluSzSINE,Alu
chr642855979AG8.12389E-06RPL7L1+TRUEAluSzSINE,Alu
chr194351063AT0.00907GCLM-FALSE
chr146828460CT0.00101NSUN4+FALSE
chr2035521049GA0.00711TLDC2,SAMHD1+,-FALSE
chr136924851TC0.00493MRPS15-TRUEAluJbSINE,Alu
chr5177576463AT0.00554.FALSE
chr322424405TA0.00766.FALSE
chr19324213CT0.00063H6PD+FALSE
chr11344749AG0.00307.FALSEAluSx1SINE,Alu
chr3195694465TC0.00300SDHAP1-FALSE
chr1146650091CA0.00361PDIA3P1+FALSE
chr237330540TC0.00854.FALSEAluSq2SINE,Alu
chr1253435627AG0.00133EIF4B+FALSE
chr1583826216CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr110518756TC0.00600.FALSEAluSx1SINE,Alu
chr738764395TC0.00139VPS41-TRUEAluSpSINE,Alu
chr126143727AT0.00917SEPN1+FALSEAluSxSINE,Alu
chr9136335345GA0.00490CACFD1+FALSE(TG)nSINE,Alu
chr7148700783GA0.00557PDIA4-FALSE
chr178029102GA0.00086ZZZ3-FALSE
chr2208619742AG0.00500CCNYL1+TRUEAluJbSINE,Alu
chr1075008846TC0.00135DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr765618876AG0.00817CRCP+TRUEAluSx3SINE,Alu
chr16282224TC0.00062ICMT-TRUEAluSzSINE,Alu
chr116944809GC0.00072CROCCP2-FALSE
chr5125961468AG2.27854E-07PHAX+TRUEAluSz6SINE,Alu
chr275787917GC0.00766EVA1A-FALSE
chr310193732AG0.00472VHL+TRUEAluJrSINE,Alu
chr9100777799GA0.00675ANP32B+FALSE
chr1205687358TC0.00692NUCKS1-FALSE(T)nSINE,Alu
chr1939874945TC0.00335SAMD4B+FALSE
chr2202030111AG0.00983CFLAR+TRUEAluSx1SINE,Alu
chr162627128AG0.00087PATJ+TRUEAluSxSINE,Alu
chr139470979CA0.00160AKIRIN1+FALSEAluSx1SINE,Alu
chr674134823TC0.00305.FALSEAluSzSINE,Alu
chr119545144GT0.00071LOC101927895,EMC1+,-FALSE
chr4103715820AC0.00652LOC102723704,UBE2D3+,-FALSE(A)nSINE,Alu
chr578532658CT0.00882JMY+FALSE
chr1179326925CT0.00284SOAT1+FALSEAluJoSINE,Alu
chr138411445GA0.00625INPP5B-FALSE
chr136068237TC0.00974PSMB2-TRUEAluScSINE,Alu
chr538478065TA0.00049LIFR-FALSE
chr1610623553TC0.00024EMP2-TRUEAluSpSINE,Alu
chr1159946783AG0.00097LINC01133+FALSE(GAAA)nSINE,Alu
chr1149943157GA0.00024OTUD7B-FALSE
chr3176742501GA0.00707TBL1XR1-FALSE(A)nSINE,Alu
chr1567783TC0.00427MIR6723-FALSE
chr1431916770TC0.00153LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr13546128AG0.00703TPRG1L+FALSEAluSzSINE,Alu
chr12125514124AG3.15634E-06.FALSE(TA)nSINE,Alu
chr2170103351GT0.00139LRP2-FALSE
chr9130268408TC6.51633E-05FAM129B-FALSE(CTCA)nSINE,Alu
chr9131872860CT0.00141CRAT-FALSE
chr1205687213TA0.00950NUCKS1-FALSE
chr342599091GA0.00196SEC22C-FALSE
chr3133307642TG0.00523CDV3+FALSE(TT)nSINE,Alu
chr197543764CT0.00901DPYD-FALSE
chr136067677TC0.00522PSMB2-TRUEAluSzSINE,Alu
chr131902343TC1.48709E-05SERINC2+FALSE
chr261405795GT0.00061AHSA2+FALSE
chr1168220363AG0.00488.FALSEAluSz6SINE,Alu
chr123381596TC0.00762KDM1A+FALSE
chr116932912TC0.00808NBPF1-FALSEL1MC2SINE,Alu
chr2198416734AT0.00257HSPE1-MOB4,MOB4+FALSE
chr111979814GA0.00041KIAA2013-FALSE
chr1298943102AG0.00250TMPO+TRUEAluSzSINE,Alu
chr146829013AG0.00360NSUN4+FALSE
chr16283264TC0.00378ICMT-TRUEAluSx3SINE,Alu
chr552389817TA0.00868ITGA2+FALSE
chr642857057AG0.00020RPL7L1+TRUEAluSpSINE,Alu
chr9115447534TC0.00203INIP-TRUEAluJbSINE,Alu
chr243625184TA0.00587THADA-FALSE
chr4104062223CT0.00750CENPE-FALSE
chr1109180686CT1.31584E-05FAM102B+FALSE
chr1420940606GA0.00710PNP+FALSE
chr1100550370TA0.00743SASS6-FALSE
chr717384354AG0.00282AHR+TRUEAluSxSINE,Alu
chr1218617066AT0.00211TGFB2-OT1,TGFB2+FALSE
chr7158679732GA0.00456WDR60+FALSE
chr744841237TA0.00599PPIA+FALSE
chr119428086GT0.00449UBR4-FALSE
chr42940434TC1.52137E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr146075604AG0.00365NASP+TRUEAluSx4SINE,Alu
chr2227662565AC0.00028IRS1-FALSE
chr72768626CT0.00228AMZ1,GNA12+,-FALSE
chr1146650363TA0.00982PDIA3P1+FALSE
chr2035521048AT0.00727TLDC2,SAMHD1+,-FALSE
chr175288083TA0.00232RABEP1+FALSE
chr744618353TC0.00168TMED4-TRUEAluSq2SINE,Alu
chr116892918TC0.00590NBPF1-FALSE
chr417802819TC0.00316DCAF16-TRUEAluSzSINE,Alu
chr133148216AG0.00036SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr110517314TC0.00617.FALSEAluJrSINE,Alu
chrX16781156AG0.00061.FALSEAluJoSINE,Alu
chr110517653TC0.00256.FALSEAluSx1SINE,Alu
chr1117532798CG0.00466PTGFRN+FALSE
chr2128950217CT0.00255UGGT1+FALSE
chr1788840TC0.00415LINC01128+FALSE
chr617951005GC0.00381KIF13A-FALSE
chr1247350690GC0.00364.FALSEL1MA7SINE,Alu
chr11273359TG0.00254DVL1-FALSE
chr119542458TC1.01966E-05LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr2152334055AG0.00064.FALSEAluYSINE,Alu
chr238975954AC0.00381SRSF7-FALSE
chr110520902AT0.00032DFFA-FALSE
chr126608017TA3.67009E-06.FALSE
chr1154128838GT0.00062TPM3-FALSE
chr2035520229TC3.77169E-05TLDC2,SAMHD1+,-FALSEAluSx3SINE,Alu
chr1590820095AG6.27827E-07.FALSEAluYSINE,Alu
chr3160969268CT0.00375NMD3+FALSE
chr1788795TG0.00333LINC01128+FALSECharlie19aSINE,Alu
chr11337736CG0.00012MRPL20-FALSE
chr1180082703CA2.04280E-05CEP350+FALSE
chr1610626615CT0.00489EMP2-FALSE(T)nSINE,Alu
chr63114457CT0.00320RIPK1+FALSE
chr3184429718AG0.00914MAGEF1-FALSE
chr1324823699GA0.00472SPATA13+FALSE
chr2171850174TG3.41223E-05TLK1-FALSE
chr830536078TC0.00509GSR-FALSEAluJrSINE,Alu
chr140537941AC0.00216CAP1+FALSE(A)nSINE,Alu
chr1148932848AG0.00496LOC645166+FALSE
chr3148748339GT0.00666HLTF-FALSE
chr811700676TC0.00534CTSB-TRUEAluSgSINE,Alu
chr1586288387CT0.00809AKAP13+FALSE
chr838829416AG0.00695PLEKHA2+TRUEAluYcSINE,Alu
chr299813003AG0.00370MRPL30+TRUEAluJbSINE,Alu
chr310193358AG0.00765VHL+TRUEL1ME4aSINE,Alu
chr110518733TC0.00399.FALSEAluSx1SINE,Alu
chr6111588769AG2.24603E-05MFSD4B+TRUEAluYm1SINE,Alu
chr116892256TC0.00468NBPF1-FALSE
chr296915238TC2.48142E-05.FALSEAluJrSINE,Alu
chr2206987738TC0.00322.FALSEAluJbSINE,Alu
chr1145688983AG0.00072NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr386991597TG0.00481VGLL3-FALSE
chr1988503AT8.91206E-06AGRN+FALSE
chr124934334AG0.00031NCMAP+TRUEAluSz6SINE,Alu
chr5130536797AG0.00841LYRM7+TRUEAluSx4SINE,Alu

Differential Expression Gene Analysis