Dataset Overview
RBPPA2G4
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR309PPC
PlatformHiSeq
Pubmed ID32252787

PA2G4 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PA2G4
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PA2G4


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr457326126AG0.00790PAICS+TRUEAluJrSINE,Alu
chr1150479901CT0.00228TARS2+FALSEAluSc8SINE,Alu
chr127877418GA0.00347AHDC1-FALSE
chr173512398TC0.00709SHPK,TRPV1-TRUEAluSxSINE,Alu
chr1269237057AG0.00259MDM2+TRUE
chr314986111TC0.00999FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1160966352TC3.14235E-07F11R-TRUEAluSgSINE,Alu
chr774169234GT8.95897E-05GTF2I+FALSE
chr641567394TA0.00717FOXP4+FALSE
chr1205687341CT0.00494NUCKS1-FALSE(T)nSINE,Alu
chr110517290TC0.00437.FALSEAluJrSINE,Alu
chr191990450AT0.00405CDC7+FALSELFSINE_VertSINE,Alu
chr657034845GA0.00581ZNF451,LOC101927211+,-FALSE
chr1144828683CG3.91144E-05NBPF20,NBPF9+FALSE
chr122855441CT0.00884ZBTB40+FALSE
chr116929148GA0.00037NBPF1-FALSELTR16B2SINE,Alu
chr1464951277TC0.00077ZBTB25-TRUEAluSpSINE,Alu
chr1151955393TC7.77942E-05S100A10-FALSE
chr439549693TC0.00170UGDH-AS1,SMIM14+,-FALSEAluSpSINE,Alu
chr3196078364GA0.00290.FALSEGA-richSINE,Alu
chr5139931627CT0.00073SRA1-FALSE
chr1205272926CT0.00690NUAK2-FALSE
chr1144606838AG0.00025NBPF20+FALSE
chr126143731AG0.00337SEPN1+FALSEAluSxSINE,Alu
chr127202844TC0.00146.FALSEAluSq2SINE,Alu
chr116889502TC5.54778E-06NBPF1-TRUEL1MC4SINE,Alu
chr128661633AG0.00053MED18+TRUEAluSgSINE,Alu
chr9132575836AC0.00546TOR1A-FALSE
chr133149266AG0.00292SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr286947783CT0.00515RNF103-CHMP3,RMND5A+,-FALSE
chr165134599GC0.00355ALG1,EEF2KMT+,-FALSE
chr119586455AG0.00296MRTO4+TRUEAluSzSINE,Alu
chr110520764TC0.00501DFFA-TRUEAluSc8SINE,Alu
chr345267321CT0.00059TMEM158-FALSE
chr1204526660AG0.00478MDM4+TRUEAluSxSINE,Alu
chr1212618715TC0.00714BORCS5+FALSE
chr125570692CT0.00095RSRP1-FALSE
chr116933327CT6.62916E-05NBPF1-FALSE
chr3124950418TA0.00039ZNF148-FALSE
chr642981525GC0.00041MEA1-FALSE
chr138275432GT0.00057MTF1-FALSE
chr128832533GA0.00761SNHG3,RCC1+FALSE
chr19160996TC0.00023.FALSEAluJbSINE,Alu
chr919376248AT0.00821.FALSE
chr1179044309AG0.00558FAM20B+TRUEAluSxSINE,Alu
chr1680636297CG0.00161CDYL2-FALSE
chr1160967755CT0.00563F11R-FALSE(T)nSINE,Alu
chr237331555TC0.00132.FALSEAluJbSINE,Alu
chr720178562TC1.84789E-06MACC1,LOC101927668-TRUEAluYSINE,Alu
chr333185036GA0.00573CRTAP+FALSEL2aSINE,Alu
chr2232319615AT8.19218E-06NCL-FALSE
chr342826041TG0.00019HIGD1A-FALSE
chr1205739266CT0.00125RAB29-FALSE
chr1179042692AG4.94937E-05FAM20B+TRUEAluSx1SINE,Alu
chr237331627TC0.00910.FALSEAluJbSINE,Alu
chr417629937GA0.00795.FALSEMER90SINE,Alu
chr116933625AG0.00536NBPF1-FALSEGA-richSINE,Alu
chr136067760TC1.59237E-06PSMB2-TRUEAluSzSINE,Alu
chr116901668TC0.00421NBPF1-FALSE
chr138326774TC0.00664INPP5B-TRUEAluJrSINE,Alu
chr76500726AT0.00560KDELR2-FALSE
chr1272096318AG0.00547TMEM19+TRUEAluSz6SINE,Alu
chr47762675CT3.92312E-07AFAP1,AFAP1-AS1+,-FALSE
chr8128944725GC0.00491PVT1+FALSE
chr1168523472TC0.00649CPT1A-TRUEAluSqSINE,Alu
chr146828700AG0.00805NSUN4+FALSE
chr1731258352GA0.00417TMEM98+FALSE
chr1118166096CT0.00861FAM46C+FALSE
chr13416449CA0.00748MEGF6-FALSE
chr116932144AC0.00559NBPF1-FALSE
chr5134086670CA0.00585CAMLG+FALSE
chr9125609943AG0.00247.FALSE
chr145976147GA0.00476MMACHC+FALSEAluJrSINE,Alu
chr274332840GC4.77205E-06TET3+FALSE
chr744047240GA0.00588POLR2J4,SPDYE1+,-FALSE
chr1149913727TC0.00721OTUD7B-TRUEMER96BSINE,Alu
chr126755291AG0.00044LIN28A+TRUEAluSx1SINE,Alu
chr1154315369CT0.00022ATP8B2+FALSE
chr237330517TC0.00324.FALSEAluSq2SINE,Alu
chr237478348TA0.00392PRKD3-FALSE
chr154635874TC0.00334.FALSEAluSxSINE,Alu
chr3100084432GA0.00321TOMM70-FALSE
chr16683561CG0.00732PHF13+FALSE
chr1179876988CG0.00047TOR1AIP1+FALSE
chr127107948GA0.00177ARID1A+FALSE
chr799636950AG0.00927ZKSCAN1+FALSEAluSx1SINE,Alu
chr2043343908GA9.03009E-05KCNK15-AS1,WISP2+,-FALSE(GC)nSINE,Alu
chr16311399AG0.00126GPR153-FALSE
chr1146650091CA0.00361PDIA3P1+FALSE
chr310191943GA2.29886E-07VHL+FALSE
chr1145511962AG0.00091NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1174551853AC0.00079RNF169+FALSE
chr4109733172TC0.00480COL25A1-FALSE
chr11252248AG0.00503CPSF3L-FALSEAluSxSINE,Alu
chrX123045407AG0.00153XIAP+TRUEAluJoSINE,Alu
chr1120267061CA0.00181PHGDH+FALSE
chr133148196AG0.00054SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr2101622889TA0.00022RPL31+FALSE
chr2224622242TC0.00873AP1S3-TRUEAluSx1SINE,Alu
chr3141879810TC0.00348GK5-FALSEAluJrSINE,Alu
chr237328075TC0.00863.FALSE
chr1110170896TC0.00140AMPD2+FALSE
chr3160219829CT0.00654KPNA4-FALSE(TA)nSINE,Alu
chr1114940228CT0.00734TRIM33-FALSE(T)nSINE,Alu
chr1169768080CA0.00980C1orf112+FALSE
chr1200522058TA0.00209KIF14-FALSEAluSgSINE,Alu
chr125893927AG0.00081LDLRAP1+FALSE
chr255516911AG0.00719CCDC88A-FALSE(GA)nSINE,Alu
chr1177977067AG0.00030LOC730102-FALSE
chr120977907AG3.34679E-05PINK1,PINK1-AS+,-FALSE
chr5145838680AG0.00395TCERG1+FALSE(GCCCAG)nSINE,Alu
chr540832555AT5.95918E-06RPL37-FALSE
chr133146255CA0.00182SYNC,RBBP4+,-FALSE
chr6114182986TA0.00316MARCKS+FALSE
chr577655342TC0.00919SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr136642420TC0.00358MAP7D1+FALSE
chr1179072966CT0.00107ABL2-FALSEMIRcSINE,Alu
chr3109049177AT0.00044DPPA4-FALSEAluSpSINE,Alu
chr1101372409TC0.00203SLC30A7+FALSE
chr320025661CT4.83976E-05RAB5A,PP2D1+,-FALSE
chr4141600320AG0.00179TBC1D9-FALSE
chr19329289CT0.00303H6PD+FALSE
chr1911256672TC9.28647E-11SPC24-TRUEAluJr4SINE,Alu
chr345722253AG0.00663LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr1100388748TC0.00445AGL+FALSE
chr116890644CT0.00174NBPF1-FALSE
chr8144940368CT0.00020EPPK1-FALSE
chr1168523055TC0.00524CPT1A-TRUEAluYSINE,Alu
chr152520866CT0.00195TXNDC12-FALSE
chr185785557TA0.00141DDAH1-FALSE
chr155207988GA0.00914MROH7-TTC4,TTC4+FALSE
chr110520202TC0.00825.FALSEAluSxSINE,Alu
chr9131093963AG0.00299COQ4+TRUEAluJoSINE,Alu
chr1145689537AG0.00593NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr110518052TC0.00791.FALSEAluJrSINE,Alu
chr10101992298TC0.00409CWF19L1-TRUEAluSq2SINE,Alu
chr133145959TG0.00755SYNC,RBBP4+,-FALSE(T)nSINE,Alu
chr344790636TC0.00083KIAA1143-TRUEAluYSINE,Alu
chr119542401TC0.00052LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1276423035AG0.00025PHLDA1-FALSE
chr116933650AG0.00258NBPF1-FALSEGA-richSINE,Alu
chr348787640TC0.00320PRKAR2A-TRUEAluSpSINE,Alu
chr1244871041TA0.00590DESI2+FALSE
chr1421929044TC3.48024E-06RAB2B-TRUEAluSpSINE,Alu
chr7937828GA0.00605ADAP1-FALSE
chr1144930596CA0.00578NBPF20,PDE4DIP+,-FALSE
chr16651457GA0.00614KLHL21-FALSE
chr1145290818CG0.00931NBPF20+FALSE
chr224223291AG0.00512UBXN2A+TRUEAluScSINE,Alu
chr340503562GA0.00017RPL14+FALSE
chr1183876182CT0.00494RGL1+FALSE
chr127212513TC0.00260GPN2-FALSE
chr255516941CT0.00110CCDC88A-FALSE
chr345960578GA0.00632FYCO1-FALSE
chr159122059GA0.00476MYSM1-FALSE
chr154691922TA0.00224SSBP3-FALSE
chr1114443618AG0.00910AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr43514695AG1.35580E-12LRPAP1-FALSE
chr110518052TC7.90759E-05.FALSEAluJrSINE,Alu
chr1159887904AT8.82173E-05TAGLN2-FALSE
chr2157440644GC0.00394GPD2+FALSE
chr159246520AC7.56706E-05JUN-FALSE
chr144459935TC0.00953CCDC24+FALSEAluJbSINE,Alu
chr1145689701AG0.00765NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr2208466270AG0.00713CREB1,METTL21A+,-FALSE
chr1272182168GC0.00867RAB21+FALSE
chr1569803GA0.00166.FALSE
chr125889176CT3.50303E-06LDLRAP1+FALSE
chr199672943TC1.63385E-06.FALSEAluSx3SINE,Alu
chr1667715890TC9.92672E-05GFOD2-TRUEAluJrSINE,Alu
chr1226171400TC0.00359SDE2-TRUEBC200SINE,Alu
chr133148698AG0.00736SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr2232319613CT0.00022NCL-FALSE
chr1144604425CT0.00269NBPF20+FALSE
chr123636275GT0.00258HNRNPR-FALSE
chr1225707042TC4.11654E-05ENAH-FALSE
chr211321880CT0.00064ROCK2-FALSEAluSx1SINE,Alu
chr14100762714TC0.00573SLC25A29-TRUEAluJoSINE,Alu
chr4119551832GA0.00522LOC729218+FALSE
chr330733690CA0.00353TGFBR2+FALSE
chr110517623TC8.06723E-05.FALSEAluSx1SINE,Alu
chr537291386TC1.33550E-08.FALSEAluSx3SINE,Alu
chr2206983267TC0.00854.FALSEAluJbSINE,Alu
chr167874697TC4.44446E-05SERBP1-TRUEAluSx3SINE,Alu
chr11634860GT0.00659CDK11B,CDK11A-FALSE
chr110521238TC0.00793DFFA-TRUEAluYSINE,Alu
chr74809089AG0.00552FOXK1+TRUEAluSx1SINE,Alu
chr88099397TC0.00975FAM86B3P+FALSE
chr317201882CT0.00282TBC1D5-FALSE
chr271298486TC0.00408NAGK+FALSE
chr285133793GA0.00577TMSB10+FALSE
chr192977228TC0.00206EVI5-TRUEAluJrSINE,Alu
chr167874697TC5.54610E-06SERBP1-TRUEAluSx3SINE,Alu
chr220401859AT0.00930SDC1-FALSE(A)nSINE,Alu
chr128939803CT1.99823E-11TAF12-FALSE
chr146033514GA0.00073AKR1A1+FALSEAluYk3SINE,Alu
chr197144546AC0.00803.FALSE
chr315483744AG0.00083EAF1+FALSE
chr145242861AG0.00911RPS8+TRUEAluSzSINE,Alu
chr237479862CT0.00603PRKD3-FALSE
chr159122910GA0.00251MYSM1-FALSE
chr116958064AG2.44983E-05.FALSE
chr119586455AG3.44081E-06MRTO4+TRUEAluSzSINE,Alu
chr1079552092CT0.00159DLG5-FALSE
chr780373463AC0.00399SEMA3C-FALSE
chr1109239335GT0.00011PRPF38B+FALSE
chr2231375015AT0.00990TUG1+FALSE
chr116893721AC0.00179NBPF1-FALSE
chr135319550CT0.00781SMIM12-FALSEAluSgSINE,Alu
chr9115447527TC0.00200INIP-TRUEAluJbSINE,Alu
chr38922054TC0.00300RAD18-FALSE
chr146077218AG0.00783NASP+TRUEAluSc8SINE,Alu
chr138326643TC0.00458INPP5B-TRUEAluJrSINE,Alu
chr19160976TC0.00015.FALSEAluJbSINE,Alu
chr127216740GA0.00801GPN2-FALSE
chr2206986380TC0.00053.FALSEAluSzSINE,Alu
chr190496713AG0.00677ZNF326+FALSE
chr119934793GA0.00068MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr2100897573GA0.00231LONRF2-FALSE
chr2242384368GA0.00031FARP2+FALSEAluJrSINE,Alu
chr226613949AG0.00669EPT1+FALSE
chr652860422GC0.00024.FALSE7SKSINE,Alu
chr439549701TC0.00269UGDH-AS1,SMIM14+,-FALSEAluSpSINE,Alu
chr144818525TC0.00442ERI3-FALSE
chr136024788CT5.60663E-14NCDN+FALSE
chr1209605646AC0.00478MIR205HG+FALSE(AGC)nSINE,Alu
chr315114288TC7.51597E-05RBSN-TRUEAluYSINE,Alu
chr1114940211GT0.00925TRIM33-FALSE(T)nSINE,Alu
chr255516891GA2.12747E-05CCDC88A-FALSE(GA)nSINE,Alu
chr1224927968GA0.00695CNIH3+FALSE
chr1610625108TC7.88488E-10EMP2-TRUEAluSx3SINE,Alu
chr1490871942CA0.00057CALM1+FALSE
chr1298942679AG2.08991E-07TMPO+FALSEAluScSINE,Alu
chr111347150CA0.00016UBIAD1+FALSE
chr1942375540AG0.00012.FALSEAluSxSINE,Alu
chr366428450GA0.00355SLC25A26+FALSE
chrX77083723TC0.00163MAGT1-TRUEAluSz6SINE,Alu
chr1753239140CT0.00954STXBP4+FALSEMIRSINE,Alu
chr291847976CT0.00010.FALSETAR1SINE,Alu
chr1225360463AT0.00118KRAS-FALSE
chr1144852167GT0.00352NBPF20,PDE4DIP+,-FALSE
chr1214529170TC0.00670PTPN14-TRUE
chr1194863483CT0.00501ENDOD1+FALSE
chr310193732AG0.00472VHL+TRUEAluJrSINE,Alu
chr1179070646TC0.00283ABL2-TRUEAluSzSINE,Alu
chr133086876TC0.00075ZBTB8OS-TRUEAluYSINE,Alu
chr811700373TC0.00212CTSB-TRUEAluSq2SINE,Alu
chr136068370TC0.00789PSMB2-TRUEAluScSINE,Alu
chr1142688707AC0.00504.FALSE
chr138278949CA0.00664MTF1-FALSEAluSpSINE,Alu
chr1953914395AG0.00227ZNF765+TRUEAluSxSINE,Alu

Differential Expression Gene Analysis