Dataset Overview
RBPMSI2
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR169QQW
PlatformHiSeq
Pubmed ID32252787

MSI2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of MSI2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of MSI2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr153366673AG0.00243ECHDC2-FALSEAluJbSINE,Alu
chr2197021372TA0.00285STK17B-FALSE
chr3196670094GC0.00017NCBP2-AS2+FALSE
chr1145512073AG0.00131NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2128950515AG0.00208UGGT1+TRUEAluScSINE,Alu
chr1221654407GA0.00654RECQL-FALSE
chr116889503TC0.00130NBPF1-FALSEL1MC4SINE,Alu
chr153289759AG0.00383ZYG11B+TRUEAluSzSINE,Alu
chr1155144757TC0.00758KRTCAP2-FALSETigger19bSINE,Alu
chr5125962354AG3.71532E-05PHAX+TRUEAluScSINE,Alu
chr145120664CT0.00437TMEM53-FALSE
chr133149256AG0.00286SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chrX123046772AG0.00548XIAP+TRUEAluSzSINE,Alu
chr193827995CT0.00714DR1+FALSE
chr177759578AG4.05543E-05AK5+FALSE
chr537290504TC0.00410.FALSEAluSzSINE,Alu
chr1931935TC0.00796.FALSE
chr123408939TA1.04314E-06KDM1A+FALSE
chr1269237534AG0.00106MDM2+TRUE
chr932425898TC0.00177ACO1+FALSE
chr128825465AG0.00756PHACTR4+TRUEAluSgSINE,Alu
chr110043504AG0.00213NMNAT1+FALSEAluSx3SINE,Alu
chr1226171400TC0.00359SDE2-TRUEBC200SINE,Alu
chr514696117TC0.00807OTULIN+FALSE
chr1131452571AG0.00084DNAJC24+TRUE
chr438016395TG0.00537TBC1D1+FALSE
chr119447843CG0.00345UBR4-FALSE
chr238971641TA0.00071SRSF7-FALSE
chr9131094270AG0.00686COQ4+TRUEAluSxSINE,Alu
chr1352989863CT0.00132VPS36-FALSE
chr2109401284GC0.00059RANBP2+FALSE
chr11550392CT0.00617.FALSEAluSgSINE,Alu
chr175288077GC0.00066RABEP1+FALSE
chr1179829595TC0.00188TOR1AIP2-TRUEAluJrSINE,Alu
chr179109352TG0.00818IFI44L+FALSELTR26SINE,Alu
chr136614708CT0.00201TRAPPC3-FALSE
chr144463185TG0.00427SLC6A9-FALSE
chr1142688506TC4.54862E-05.FALSE
chr147716043AG0.00794STIL-FALSE
chr1209796329TA0.00136LAMB3-FALSE
chr146828460CT0.00393NSUN4+FALSE
chr237328075TC0.00863.FALSE
chr110043527AG0.00811NMNAT1+TRUEAluSx3SINE,Alu
chr126606589CG0.00420SH3BGRL3+FALSE
chr315114293TC2.60553E-05RBSN-TRUEAluYSINE,Alu
chr129464349AC0.00042LOC642846+FALSE
chr129508350CT0.00859SRSF4-FALSE(GGC)nSINE,Alu
chr1220231254TC0.00974RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr315483830AG3.44106E-05EAF1+FALSE
chr116913677TC0.00638NBPF1-FALSE
chr1100490275AG0.00142SLC35A3+TRUEAluSc5SINE,Alu
chr1109180686CT1.31584E-05FAM102B+FALSE
chr63021465TC0.00029HTATSF1P2-TRUEAluJr4SINE,Alu
chr110043358AG0.00982NMNAT1+TRUEAluSx3SINE,Alu
chr239009355AG0.00079.FALSEAluSx3SINE,Alu
chr11125763746CG0.00166HYLS1,PUS3+,-FALSE
chr144818529TC0.00310ERI3-FALSE
chr1146627405CG0.00074PRKAB2-FALSE
chr1118068558GA0.00644.FALSE
chr1477581481CA0.00997CIPC+FALSE
chr356654248TG3.99921E-06CCDC66,FAM208A+,-FALSE
chr11650832AG0.00263CDK11B,CDK11A-FALSE
chr224494671TC0.00244ITSN2-FALSE(TATCCT)nSINE,Alu
chr1939433142TA0.00215FBXO17-FALSEAluJbSINE,Alu
chr1957802824GA0.00924ZNF460+FALSE
chr1211921702TC1.94235E-05LPGAT1-FALSE
chr145244413TA0.00748.FALSE
chr133148623AG0.00221SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr119934839AG0.00052MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1214529725TC0.00535PTPN14-TRUE
chr4129795660TA0.00454JADE1+FALSE
chr674133914TC0.00014.FALSEAluYSINE,Alu
chr128573293GA0.00059.FALSE
chr19161218TC0.00581.FALSEAluSxSINE,Alu
chr1179044110AG0.00885FAM20B+TRUEAluSxSINE,Alu
chr232534897AG0.00680.FALSEAluSx1SINE,Alu
chr3122283289CA0.00072DTX3L,PARP9+,-FALSE
chr237328034TC8.99638E-05.FALSE
chr187328433TC3.09926E-06SEP15-FALSE
chr116893721AC0.00043NBPF1-FALSE
chr1236744712CA0.00054HEATR1-FALSE
chr1148594563GT0.00169NBPF15+FALSE
chr152816691TC0.00353CC2D1B-TRUEAluSx1SINE,Alu
chr12133298355AG0.00024PGAM5+TRUEAluSpSINE,Alu
chr12125511226AG0.00205THRIL-FALSEAluSx1SINE,Alu
chr633385535AG0.00671.FALSE
chr153289547AG0.00505ZYG11B+TRUEAluSzSINE,Alu
chr131732602CA0.00148SNRNP40-FALSE
chr1228880021CT4.50271E-05RHOU+FALSE
chr116912099GC0.00928NBPF1-FALSE
chr1148004440CA0.00082NBPF8-FALSE
chr1120839682AG0.00073FAM72B+FALSE
chr2219523584CT0.00299ZNF142-FALSE
chr1201845903AG0.00041IPO9+FALSE
chr1169101307CT0.00405ATP1B1+FALSE
chr39935263AG1.04104E-09JAGN1+FALSE
chr1162497663GA0.00335UHMK1+FALSE
chr1921367088AG0.00018ZNF431+TRUEAluScSINE,Alu
chr127074517CT0.00369PHB2-FALSE
chr162882267GC0.00252ZG16B+FALSE
chr162673225GA0.00039L1TD1+FALSEL1MEdSINE,Alu
chr1274934944AG0.00094ATXN7L3B+FALSE
chr310065426CT0.00776CIDECP-FALSE
chr1738438362GA0.00016WIPF2+FALSEA-richSINE,Alu
chr827661036CA0.00339ESCO2+FALSEA-richSINE,Alu
chr5139931630AT0.00052SRA1-FALSE
chr6160211656GT0.00339MRPL18+FALSE
chr16614230GA0.00509NOL9-FALSE
chr7116147752AG0.00031CAV2+FALSE(AAAAGAAA)nSINE,Alu
chr2102484488AG0.00192MAP4K4+FALSE
chr237331565TC0.00121.FALSEAluJbSINE,Alu
chr115818065TC0.00372CASP9-TRUEAluJbSINE,Alu
chr3124950421TA0.00713ZNF148-FALSE
chr110517513TC0.00982.FALSEAluSx1SINE,Alu
chr247387307GT0.00035CALM2-FALSE
chr162627128AG0.00087PATJ+TRUEAluSxSINE,Alu
chr571654855GC0.00414PTCD2+FALSE
chr203905907AG0.00325PANK2+TRUEAluSxSINE,Alu
chr1138156GT0.00177LOC729737-FALSE
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr147074462AG0.00011MOB3C-FALSE
chr110518613AT0.00819.FALSEAluSx1SINE,Alu
chr119543249TC0.00564LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1173457017CT0.00036PRDX6+FALSE
chr1936575645GA0.00590WDR62+FALSE
chr1475202704AG2.33511E-06FCF1+TRUEAluScSINE,Alu
chr8104082307CT0.00675ATP6V1C1+FALSEL1ME3GSINE,Alu
chr288913273GC0.00152EIF2AK3-FALSE
chr4177251290GA0.00580SPCS3+FALSE
chr119542458TC0.00113LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr398307696TG3.25383E-09CPOX-FALSE
chr436121336TG0.00183ARAP2-FALSE
chr19328094AG0.00107H6PD+TRUEAluJrSINE,Alu
chr573932315TC0.00420ENC1-FALSE
chr124296849TC0.00125.FALSE
chr1675479910TC0.00026TMEM170A-TRUEAluSg4SINE,Alu
chr1179044206AG0.00458FAM20B+TRUEAluSxSINE,Alu
chr2229890660AG0.00596PID1-FALSE
chr5149829072GT0.00816RPS14-FALSE
chr49909923GA0.00416SLC2A9-FALSE
chr537290492TC8.25709E-07.FALSEAluSzSINE,Alu
chr210074384GA0.00765TAF1B+FALSE
chr1109818160TG3.82986E-06CELSR2+FALSE
chr7158719116AG0.00824WDR60+FALSE
chr175289028GA0.00849RABEP1,NUP88+,-FALSE
chr1193054575CG0.00029TROVE2+FALSE(ATTTT)nSINE,Alu
chr540832551AT0.00394RPL37-FALSE
chr574072638GA0.00431NSA2+FALSE
chr16583457TC9.96562E-05NOL9-TRUEAluSqSINE,Alu
chr1810691357GA0.00082PIEZO2-FALSE
chr2196602326TG0.00503SLC39A10+FALSE
chr110438014AC0.00046KIF1B+FALSE
chr1168220489AG0.00126.FALSEAluSz6SINE,Alu
chr2152334349AG0.00171.FALSEAluSqSINE,Alu
chr2272203CT0.00064ACP1+FALSE
chr9125866693CT0.00255RABGAP1+FALSE
chr1472041443CT0.00842SIPA1L1+FALSE
chr1256510709GA0.00047RPL41+FALSE
chr178414310CA0.00131FUBP1-FALSE
chr2043343908GA9.03009E-05KCNK15-AS1,WISP2+,-FALSE(GC)nSINE,Alu
chr3125033835TG0.00385ZNF148-FALSEAluJbSINE,Alu
chr1894378TA0.00068NOC2L-FALSE
chr1162557871GC0.00273TMEM179B,TMEM223+,-FALSE
chr1179044181AG1.64117E-06FAM20B+TRUEAluSxSINE,Alu
chr10101992793TC0.00407CWF19L1-TRUEAluJbSINE,Alu
chr1681064560AG0.00014CENPN+TRUEAluSgSINE,Alu
chr1051613231TC2.61914E-05TIMM23B,TIMM23+,-FALSE
chr1423300642CA0.00266MRPL52+FALSEMIRbSINE,Alu
chr717384882AG8.88136E-05AHR+TRUEAluScSINE,Alu
chr644417182AG0.00018CDC5L+TRUEFLAM_CSINE,Alu
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr3112320485TC0.00107LINC01279-TRUEAluJbSINE,Alu
chr237328034TC1.98403E-05.FALSE
chr3194349178CT0.00881TMEM44-FALSE
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr349395693CG0.00243GPX1-FALSE(GCC)nSINE,Alu
chr237331037TC0.00036.FALSEAluSx1SINE,Alu
chrX77084017TC0.00179MAGT1-TRUEAluSzSINE,Alu
chr1942753649GC0.00723ERF-FALSE
chr1144606963GT0.00337NBPF20+FALSE
chr1681064533AG0.00686CENPN+TRUEAluSgSINE,Alu
chr856985610AT0.00041RPS20-FALSE
chr320025663GT0.00612RAB5A,PP2D1+,-FALSE
chr1235272660CT0.00111TOMM20-FALSETigger10SINE,Alu
chr2206986233TC0.00491.FALSEAluSzSINE,Alu
chr1179042580AG0.00995FAM20B+TRUEAluSx1SINE,Alu
chr6111588769AG2.24603E-05MFSD4B+TRUEAluYm1SINE,Alu
chr19328086GA0.00017H6PD+FALSEAluJrSINE,Alu
chr1061548855GT0.00070CCDC6-FALSE
chr596110979AT0.00020ERAP1-FALSE
chr133068221AG0.00448ZBTB8A+TRUEAluYSINE,Alu
chr1176132119GC0.00134RFWD2-FALSEL3bSINE,Alu
chr146075171AC0.00140NASP+FALSEA-richSINE,Alu
chr5151041876GT5.29152E-05SPARC-FALSE
chr27036682AT0.00335RSAD2+FALSE
chr340503561AT0.00012RPL14+FALSE
chr195392593CT0.00173CNN3-FALSE(GGCGCG)nSINE,Alu
chr274332840GC4.77205E-06TET3+FALSE
chr286252025TC3.86923E-05POLR1A-TRUEAluSq2SINE,Alu
chr246612340GT3.13955E-05EPAS1+FALSE
chr11768386TC0.00208PDDC1-TRUEAluScSINE,Alu
chr1168523472TC0.00649CPT1A-TRUEAluSqSINE,Alu
chr3195694454CT0.00307SDHAP1-FALSE
chr914921850AG0.00112.FALSE
chr1145116149TA0.00585NBPF20,SEC22B+FALSE
chr1423795222TG0.00162BCL2L2-PABPN1,PABPN1+FALSE
chr286249961TC0.00368LOC90784-TRUEAluJrSINE,Alu
chr1144922583GA0.00101NBPF20,PDE4DIP+,-FALSE
chr13730332TC6.29937E-05CEP104-TRUEAluSx3SINE,Alu
chr194335335GT0.00425DNTTIP2-FALSE
chr126898378CA0.00148RPS6KA1+FALSE
chr5134236311AT0.00025TXNDC15+FALSEAluSqSINE,Alu
chr19161245TC0.00071.FALSEAluSxSINE,Alu
chr120945055CT0.00269CDA+FALSE
chr3186838874GA0.00972RPL39L-FALSE
chr1100440563AG0.00732SLC35A3+FALSEAluJbSINE,Alu
chr144463185TG0.00397SLC6A9-FALSE
chr1913054924AC0.00982CALR+FALSE
chr3122291688AG0.00597DTX3L+FALSEAluSzSINE,Alu
chr1138980GT0.00608LOC729737-FALSE
chr128567501AG0.00887.FALSE
chr224223353AG0.00083UBXN2A+TRUEAluScSINE,Alu
chr1566933AG3.50078E-05.FALSE
chr353260620TG0.00069TKT-FALSE
chr5125962086AG0.00231PHAX+TRUEAluSzSINE,Alu
chr1114306374GA0.00124RSBN1-FALSE
chr1179326847AG0.00846SOAT1+TRUEAluJoSINE,Alu
chr154412181TC0.00524LRRC42+FALSE
chr110043053AG0.00318NMNAT1+TRUEAluScSINE,Alu
chr1156233189CT5.51743E-05SMG5-FALSE
chr1095163809GT0.00453MYOF-FALSE
chr1184663537AC0.00256EDEM3-FALSE
chr720178567TC1.15326E-05MACC1,LOC101927668-TRUEAluYSINE,Alu
chr3196082911TC0.00250UBXN7-FALSE
chr1625269014GC0.00235.FALSE
chr119585903GA0.00522MRTO4+FALSEAluJrSINE,Alu
chr2178406765TA0.00325AGPS+FALSE
chr488061645TA0.00049AFF1+FALSE(TATAT)nSINE,Alu
chr5140751128CG0.00647PCDHGA1,PCDHGA2,PCDHGA3,PCDHGB1,PCDHGA4,PCDHGB2,PCDHGA5,PCDHGB3+FALSE
chr5151041886TG0.00176SPARC-FALSE
chr1109535117CT0.00211WDR47-FALSE
chr657034840TG0.00581ZNF451,LOC101927211+,-FALSE
chr2018469054TC0.00522RBBP9-TRUEAluJrSINE,Alu
chr657034841GT0.00581ZNF451,LOC101927211+,-FALSE
chr830536078TC0.00509GSR-FALSEAluJrSINE,Alu
chr167451522AT0.00883MIER1+FALSE
chr153291382AG0.00114ZYG11B+TRUEAluJrSINE,Alu
chr261764916AC0.00189XPO1-FALSE(AC)nSINE,Alu
chr119934839AG0.00605MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr133149495AG0.00421SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr352448770AG0.00498PHF7+TRUEAluJbSINE,Alu
chr116841561GA0.00025.FALSE
chr2176792357AG7.02808E-05LNPK-FALSE
chr191486839TC0.00514ZNF644-FALSE
chr791502407CG0.00183MTERF1-FALSE
chr856985612GT0.00028RPS20-FALSE
chr18045340CA0.00059PARK7+FALSE
chr138326728TC0.00399INPP5B-TRUEAluJrSINE,Alu
chr189447856AG0.00465KYAT3,RBMXL1-FALSE
chr42940347TC1.36349E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1215035081TC0.00951MGP-FALSE
chr116889423GC6.92544E-07NBPF1-FALSEL1MC4SINE,Alu
chr3172115589GT0.00435FNDC3B+FALSE
chr145987539CA0.00660PRDX1-FALSE
chr16583592TC0.00012NOL9-TRUEAluSqSINE,Alu
chr1475202645AG3.73418E-05FCF1+TRUEAluScSINE,Alu
chr643738977CT0.00088VEGFA+FALSE
chr1145281408CT0.00087NBPF20,NOTCH2NL+FALSE
chr112040479TC0.00505MFN2+FALSE
chr116933637AG0.00062NBPF1-FALSEGA-richSINE,Alu
chr9132268442AG0.00642LINC00963+TRUEAluJbSINE,Alu
chr812880246AG0.00012KIAA1456+TRUEAluJoSINE,Alu
chr642854739AC0.00671RPL7L1+FALSEAluScSINE,Alu
chr176252687TC0.00021RABGGTB+FALSE
chr3156259299TC0.00097SSR3-TRUEAluSq2SINE,Alu
chr1186946912GA0.00414PLA2G4A+FALSE
chr642857136AG2.38933E-09RPL7L1+TRUEAluSpSINE,Alu
chr1272182168GC0.00867RAB21+FALSE
chr210567337GC0.00940HPCAL1+FALSE
chr1100316589AG0.00147AGL+FALSE
chr127205044TC0.00312.FALSEAluSxSINE,Alu

Differential Expression Gene Analysis