Dataset Overview
RBPXRCC5
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR732IYM
PlatformHiSeq
Pubmed ID32252787

XRCC5 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of XRCC5
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of XRCC5


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1542859922AG0.00731HAUS2+TRUEAluSx1SINE,Alu
chr11118915753TC8.93388E-07HYOU1-FALSE
chr1109535117CT0.00211WDR47-FALSE
chr101086804TA0.00821IDI2-AS1,IDI1+,-FALSE
chr1743002237CA0.00141KIF18B-FALSE
chr1237064432CG0.00019MTR+FALSE
chr3141879810TC0.00348GK5-FALSEAluJrSINE,Alu
chr596372165GA0.00149.FALSE
chr398299365TG3.92075E-11CPOX-FALSE
chr119543353TC0.00377LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr299812815AG0.00245MRPL30+TRUEAluJbSINE,Alu
chr2191065246TA0.00594C2orf88+FALSE
chr2203741065TC2.92684E-06.FALSE
chr125688276AG0.00187TMEM50A+FALSE
chr388104072TA0.00815CGGBP1-FALSE
chr11344893AG0.00186.FALSEAluSgSINE,Alu
chr16695423TG9.25675E-05THAP3,DNAJC11+,-FALSE
chr720177664TC0.00089MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr438946758GA0.00294FAM114A1+FALSE
chr1075008815TC5.77576E-09DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr12522392GA0.00227FAM213B,MMEL1+,-FALSE
chr145975740CG0.00096MMACHC+FALSEAluSx4SINE,Alu
chr5122165482CT0.00367SNX2+FALSE(AC)nSINE,Alu
chr11119533726AG0.00169NECTIN1-FALSE
chr1145512951AG4.65248E-05NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr286249961TC0.00262LOC90784-TRUEAluJrSINE,Alu
chr1911257673TC0.00155SPC24-TRUEAluSpSINE,Alu
chr594050487TA0.00380MCTP1-FALSE
chr11252441TC0.00086CPSF3L-TRUEAluJrSINE,Alu
chr333187831CT6.36740E-05CRTAP+FALSE
chr2045839074AT0.00019ZMYND8-FALSE(T)nSINE,Alu
chr1160967855TC0.00042F11R-TRUEAluSpSINE,Alu
chr357612180TC0.00018DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr7299881AG1.23967E-06FAM20C+FALSE
chr310005159AT0.00939EMC3-FALSE(AT)nSINE,Alu
chr133071146AG0.00899ZBTB8A+TRUEAluSx1SINE,Alu
chr110517635TC0.00124.FALSEAluSx1SINE,Alu
chr16259433GA0.00522RPL22-FALSEG-richSINE,Alu
chr6160101733TC0.00784SOD2-TRUEAluSzSINE,Alu
chr119199221CT0.00676ALDH4A1-FALSE
chr9131872860CT0.00141CRAT-FALSE
chr116932368TA0.00336NBPF1-FALSEMLT1F-intSINE,Alu
chr5176887511AC0.00662DBN1-FALSE
chr417628548AG0.00991.FALSEAluSzSINE,Alu
chr1648388382AG0.00301MIR5095+TRUEAluSzSINE,Alu
chr111141187CG0.00814EXOSC10-FALSE
chr479832870AT0.00655BMP2K+FALSE
chr1736936846CT0.00277PIP4K2B-FALSE
chr146076599AG0.00116NASP+TRUEAluSxSINE,Alu
chr310285030GA0.00384IRAK2+FALSE
chr1965489CA0.00494WASH5P-FALSEL2bSINE,Alu
chr1100489452AG0.00741SLC35A3+TRUEAluScSINE,Alu
chr1894378TA0.00068NOC2L-FALSE
chr514510071GT0.00130TRIO+FALSE
chr115904318CT9.04121E-06AGMAT-FALSE
chr1109818161CT0.00840CELSR2+FALSE
chr631595882CA0.00450.FALSE
chr2206987136TC0.00189.FALSEAluSxSINE,Alu
chr457327017AG4.29594E-07PAICS+TRUEAluSx1SINE,Alu
chr1453242354TC3.85910E-06GNPNAT1-TRUEAluJoSINE,Alu
chr1100440553AG0.00553SLC35A3+TRUEAluJbSINE,Alu
chr143272842AT5.86577E-06SVBP-FALSE
chr191486838GC0.00514ZNF644-FALSE
chr3136573440AG0.00038NCK1-AS1,SLC35G2+,-FALSE
chr1622296860AG0.00041EEF2K+TRUEAluJoSINE,Alu
chr285776644TC0.00127GGCX-TRUEAluSz6SINE,Alu
chr348787052TC0.00226PRKAR2A-TRUEAluSx3SINE,Alu
chr1148595665AG0.00378NBPF15+TRUEL1MC4SINE,Alu
chr1203821865CT0.00222ZC3H11A+FALSE
chr146033514GA0.00073AKR1A1+FALSEAluYk3SINE,Alu
chr3196077460GT0.00416.FALSE
chr168168152CT0.00258GNG12-FALSE
chr5125961532AG0.00039PHAX+TRUEAluSz6SINE,Alu
chr144035352CT0.00055PTPRF+FALSE
chr2234749258TC0.00710HJURP-FALSE
chr540830050TC0.00042.FALSEAluSpSINE,Alu
chr541917695CT0.00019C5orf51+FALSE
chr671298639AG0.00339.FALSEAluSpSINE,Alu
chr174929004AG0.00030KIF1C+TRUEAluYSINE,Alu
chr2134729969AG0.00077IFNAR1+TRUEAluSg7SINE,Alu
chr125688276AG0.00015TMEM50A+FALSE
chr1200521297CT0.00133KIF14-FALSE(T)nSINE,Alu
chr1144053662TG0.00173.FALSE
chr643738977CT0.00088VEGFA+FALSE
chr120976023TC6.30669E-06PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr128825337AG0.00191PHACTR4+TRUEAluSgSINE,Alu
chr729960462GA5.89775E-06SCRN1-FALSE
chr2220037666AG0.00796CNPPD1-FALSE
chr1225707044CT1.61826E-07ENAH-FALSE
chr674134008TC0.00337.FALSEAluYSINE,Alu
chr1542861741AG0.00200HAUS2+TRUEAluJbSINE,Alu
chr9125609939AT0.00693.FALSE
chr165134599GC0.00355ALG1,EEF2KMT+,-FALSE
chr3156258319TC0.00012SSR3-TRUEAluYk3SINE,Alu
chr811700231TC1.53992E-05CTSB-TRUEAluSq2SINE,Alu
chr132372358CT0.00303PTP4A2-FALSE(CA)nSINE,Alu
chr721941583CA0.00499CDCA7L-FALSE
chr531554098GT2.66454E-15C5orf22+FALSE
chr19162348TC0.00359.FALSEAluSxSINE,Alu
chr7158719116AG0.00824WDR60+FALSE
chr1421929014TC0.00749RAB2B-TRUEAluSpSINE,Alu
chr1610625437TC0.00028EMP2-TRUEAluSxSINE,Alu
chr6143661166AC0.00536AIG1+FALSE
chr116927369CT0.00943NBPF1-FALSE
chr11677253TC0.00145SLC35E2-FALSE
chr1145693061AG0.00158NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr618264355GA0.00872DEK-FALSE
chr1421929044TC3.48024E-06RAB2B-TRUEAluSpSINE,Alu
chr842876058AG0.00029HOOK3+TRUEAluSq2SINE,Alu
chr1773886219TC8.52474E-05TRIM65-TRUEFRAMSINE,Alu
chrX84532996TG0.00801POF1B-FALSE
chr799917927TC0.00320SPDYE3+FALSEAluJbSINE,Alu
chr42940265TC4.71601E-06NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1144595886GA0.00205NBPF20+FALSEAluJbSINE,Alu
chr345722047AG0.00085LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr914764CT0.00491WASH1-FALSE
chr644417142AG0.00144CDC5L+TRUEFLAM_CSINE,Alu
chr9132268442AG0.00642LINC00963+TRUEAluJbSINE,Alu
chr2206987738TC0.00322.FALSEAluJbSINE,Alu
chr1175526481CA0.00995UVRAG+FALSE
chr1266516911AT0.00067LLPH-FALSE
chr1155142927AG0.00877KRTCAP2-FALSE
chr996438975TC0.00042PHF2+FALSE(CTCCAC)nSINE,Alu
chr110517653TC0.00792.FALSEAluSx1SINE,Alu
chr2101010082GC0.00965CHST10-FALSE
chr439550978TC0.00023UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr10104417856TA0.00616TRIM8+FALSE(AAT)nSINE,Alu
chr1073994158AG0.00110ANAPC16+TRUEAluJrSINE,Alu
chr6109784327TC2.38076E-05MICAL1,ZBTB24-TRUEAluSgSINE,Alu
chr5125962568AG0.00015PHAX+TRUEAluSzSINE,Alu
chr126143725AT0.00920SEPN1+FALSEAluSxSINE,Alu
chr132833541TC0.00903BSDC1-TRUE
chr117393889AG0.00390PADI2-FALSE
chr417804872TC0.00096DCAF16-TRUEAluSxSINE,Alu
chr1674655596TG0.00028RFWD3-FALSEAluSxSINE,Alu
chr120982631GA0.00133DDOST-FALSE
chr116889502TC0.00178NBPF1-TRUEL1MC4SINE,Alu
chr128662213AG0.00013MED18+TRUEAluSq2SINE,Alu
chr4129795663TA0.00165JADE1+FALSE
chr3179042832AG0.00308ZNF639+TRUEAluSpSINE,Alu
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr191990450AT0.00091CDC7+FALSELFSINE_VertSINE,Alu
chr110518591AT0.00545.FALSE
chr1231557255CG0.00056EGLN1-FALSE(GCC)nSINE,Alu
chr128836900AG0.00018SNHG3,RCC1+TRUEAluScSINE,Alu
chr256150864CT0.00615EFEMP1-FALSE
chr8101932094TA0.00288YWHAZ-FALSEMER34B-intSINE,Alu
chr2233446265TC0.00177EIF4E2+FALSE
chr2232319583CA0.00801NCL-FALSEA-richSINE,Alu
chr230863651AT0.00366LCLAT1+FALSE
chr315114759GA0.00595RBSN-FALSE
chr204680094CT0.00438PRNP+FALSE
chr4152025793TA0.00675RPS3A+FALSE
chr1150446673AG2.11627E-07RPRD2+FALSE
chr156961756AG0.00265PLPP3-FALSE
chr3179117164TC0.00234GNB4-FALSEAluSzSINE,Alu
chr124935337AG0.00773NCMAP+TRUEAluJbSINE,Alu
chr1118167515CT3.85084E-05FAM46C+FALSE
chr110517313TC0.00661.FALSEAluJrSINE,Alu
chr1145281543CT0.00028NBPF20,NOTCH2NL+FALSE
chr43770069GC0.00018ADRA2C+FALSE
chr799649179AG0.00360ZSCAN21+TRUEAluYSINE,Alu
chr2204055625GA0.00426NBEAL1+FALSE
chr348632596AG0.00666.FALSE
chr1211917176CT0.00498LPGAT1-FALSE
chr375474643TC0.00850FAM86DP-TRUEAluJoSINE,Alu
chr140214261AG0.00879PPIE+TRUEAluSq2SINE,Alu
chr116889513TC0.00777NBPF1-TRUEL1MC4SINE,Alu
chr16583457TC0.00075NOL9-TRUEAluSqSINE,Alu
chr891637754AT0.00297TMEM64-FALSE
chr3124488267GA3.46260E-06ITGB5-FALSE
chr153288924AG0.00099ZYG11B+TRUEAluJoSINE,Alu
chr3101576175TC0.00246NFKBIZ+FALSE
chr1965146GA0.00761WASH5P-FALSE
chr1089623860CG0.00071PTEN+FALSE(CGG)nSINE,Alu
chr2191745643AC0.00011GLS+FALSE(GCA)nSINE,Alu
chr1116234313AG0.00016VANGL1+FALSE
chr133149495AG0.00652SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1118502750TC0.00922WDR3,SPAG17+,-FALSE(GT)nSINE,Alu
chr136535590AG0.00301.FALSEAluSx1SINE,Alu
chr72294401AG0.00035SNX8-FALSE
chr12133298355AG0.00024PGAM5+TRUEAluSpSINE,Alu
chr119585493AG0.00199MRTO4+TRUEAluSc8SINE,Alu
chrX77083617TC3.46806E-05MAGT1-TRUEAluSz6SINE,Alu
chr5174955746GC0.00768SFXN1+FALSE
chr439552646TC0.00555UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr136068231TC0.00121PSMB2-TRUEAluScSINE,Alu
chr171683647TC0.00763SMYD4-TRUEAluJbSINE,Alu
chr2206983132TC0.00861.FALSEAluJbSINE,Alu
chr1610623558TC0.00103EMP2-TRUEAluSpSINE,Alu
chr1145512925AG0.00238NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr9128729384GC0.00059PBX3+FALSE
chr315113694TC0.00622RBSN-TRUEAluSz6SINE,Alu
chr116890607GA0.00869NBPF1-FALSE
chr11252468TC0.00096CPSF3L-TRUEAluJrSINE,Alu
chr1542859452AG0.00123HAUS2+TRUEAluJbSINE,Alu
chr128835201CT0.00371SNHG3,RCC1,SNORA73B+FALSEU17SINE,Alu
chr2101587455CT0.00178NPAS2+FALSE
chr1675479910TC0.00026TMEM170A-TRUEAluSg4SINE,Alu
chr154231850TA0.00681NDC1-FALSE
chr2201774342TC0.00127.FALSEAluSzSINE,Alu
chr2206861649TA0.00066INO80D-FALSE
chr133148740AG0.00210SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr11653093AG0.00768CDK11B,CDK11A-FALSEL2SINE,Alu
chr537290400TC0.00282.FALSEAluSzSINE,Alu
chr167874696TC0.00014SERBP1-TRUEAluSx3SINE,Alu
chr5112312528TC0.00827DCP2+FALSE
chr133148216AG0.00824SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr128261657CT0.00327SMPDL3B+FALSE
chr153292607TA0.00680ZYG11B+FALSE
chr211966317TC0.00011LPIN1+FALSE
chr3156258230TC0.00176SSR3-TRUEAluYk3SINE,Alu
chr154412181TC0.00524LRRC42+FALSE
chr11594498CT0.00024CDK11B,SLC35E2B-FALSE
chr7107789927TC0.00111NRCAM-FALSE
chr195363041CT0.00105CNN3-FALSE
chr1610624996TC0.00059EMP2-TRUEAluSx3SINE,Alu
chr11595074TC0.00296CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr7123390058AG0.00102.FALSE
chr574669972CT0.00113COL4A3BP-FALSE
chr1154989595TC0.00264ZBTB7B+FALSE
chr439289308GC0.00509RFC1-FALSE
chr633384326AT0.00678.FALSE
chr1146650289CT0.00024PDIA3P1+FALSE
chr254120820GA0.00262PSME4-FALSE
chr11125452298AG0.00583EI24,STT3A-AS1+,-FALSE
chr119984100GC0.00037MINOS1-NBL1,NBL1+FALSE
chr138327586CT0.00198INPP5B-FALSEAluSx3SINE,Alu
chr13545191CT0.00597TPRG1L+FALSE
chr324019987AC0.00563NR1D2+FALSE
chr160340527GA0.00027HOOK1+FALSE
chr159121036AC0.00467MYSM1-FALSE
chr417802783TC0.00509DCAF16-TRUEAluSzSINE,Alu
chr119542456TC0.00193LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr128865502GA0.00073RCC1+FALSE
chr19162224TC0.00372.FALSEAluSxSINE,Alu
chr116524869TC0.00164ARHGEF19-FALSE
chr1138156GT0.00413LOC729737-FALSE
chr111979807CA0.00574KIAA2013-FALSE
chr1145100772AG0.00945NBPF20,SEC22B+TRUEAluSg4SINE,Alu
chr521883662TG0.00108CDH12-FALSE
chr2242384528GT2.14488E-07FARP2+FALSEAluJrSINE,Alu
chr1959095573AG0.00169CENPBD1P1+TRUEAluJbSINE,Alu
chr495588274GA0.00095PDLIM5+FALSE
chr5125961623AG6.78430E-09PHAX+TRUEAluSz6SINE,Alu
chr121545089CT0.00834ECE1-FALSEAluSx1SINE,Alu
chr1464152514TC1.52259E-06SGPP1-TRUE(TA)nSINE,Alu

Differential Expression Gene Analysis