Dataset Overview
RBP
XRCC5
Knock-Method
shRNA
RBP Family
Non-canonical_RBP
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR732IYM
Platform
HiSeq
Pubmed ID
32252787
XRCC5 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of XRCC5
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
9.32
3.98
-1.18746
4.47647E-16
7.71006E-15
A2M
2342.22
2048.82
-0.19267
0.01427
0.02824
AAAS
28.52
21.31
-0.44128
5.54625E-06
2.29442E-05
AACS
15.41
10.09
-0.63657
1.21148E-10
1.03922E-09
AADAT
6.38
8.47
0.54426
2.98101E-06
1.30534E-05
AAED1
6.05
9.36
0.61694
4.81542E-09
3.36237E-08
AAGAB
9.04
11.61
0.42442
3.29241E-05
0.00012
AAK1
2.94
4.34
0.59412
1.23002E-05
4.78779E-05
AAMDC
19.44
14.13
-0.48152
0.00327
0.00764
AAMP
122.18
98.75
-0.43300
2.71465E-05
9.85895E-05
Showing 1 to 10 of 7,779 entries
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Function Analysis of Target Genes of XRCC5
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC6
16249648_16249711_16248729_16248888_16251519_16251666
0.00780
-0.136
DataSet_01_464
View details
ABI2
204276007_204276094_204267298_204267457_204281630_204281804
0.00100
-0.167
DataSet_01_464
View details
ACP1
272036_272116_271865_271939_272191_273155
0.00633
-0.125
DataSet_01_464
View details
ACSS2
33509765_33509906_33509450_33509669_33511125_33511234
0.00011
-0.051
DataSet_01_464
View details
ACSS2
33509765_33509795_33509610_33509669_33511125_33511234
0.00041
-0.051
DataSet_01_464
View details
ADD3
111892062_111892158_111890120_111890244_111893083_111893969
0.00572
0.27
DataSet_01_464
View details
AFMID
76200736_76200822_76198783_76198832_76200908_76200981
0.00915
0.148
DataSet_01_464
View details
AFP
74310709_74310839_74309063_74309161_74315051_74315184
0.00041
-0.017
DataSet_01_464
View details
AFP
74313330_74313393_74309063_74309161_74315051_74315184
0.00076
-0.485
DataSet_01_464
View details
AHSG
186337663_186337729_186336300_186336426_186338374_186339089
0.00019
0.013
DataSet_01_464
View details
Showing 1 to 10 of 287 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAT1
108002633_108002681_108004546_108004664_107992293_107992405
0.00001
-0.18
DataSet_01_464
View details
ACAT1
108005868_108005969_108009624_108009768_108004947_108005043
0.00006
-0.125
DataSet_01_464
View details
ACP1
272036_272150_275139_275201_271865_271939
0.00011
-0.174
DataSet_01_464
View details
ADAM9
38928816_38928922_38933665_38933794_38913095_38913291
0.00108
-0.047
DataSet_01_464
View details
AFP
74306318_74306530_74309067_74309161_74303890_74304023
0.00005
-0.51
DataSet_01_464
View details
AFP
74309063_74309161_74313178_74313393_74308012_74308145
0.00543
-0.068
DataSet_01_464
View details
AHSG
186336285_186336426_186337645_186337729_186334975_186335139
0.00009
-0.007
DataSet_01_464
View details
AHSG
186334975_186335139_186336324_186336426_186334231_186334316
0.00088
-0.16
DataSet_01_464
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AHSG
186336300_186336426_186337645_186337729_186334975_186335139
0.00161
-0.006
DataSet_01_464
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ALB
74272345_74272478_74275071_74275140_74270017_74270123
0.00169
-0.384
DataSet_01_464
View details
Showing 1 to 10 of 138 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101576820_101576968_101576820_101576953_101577064_101577241
0.00532
-0.381
DataSet_01_464
View details
ACSS2
33509588_33509795_33509588_33509669_33511125_33511234
0.00232
-0.028
DataSet_01_464
View details
AFMID
76201173_76201328_76201173_76201271_76201520_76201599
0.00005
-0.262
DataSet_01_464
View details
AP1G2
24036805_24036992_24036947_24036992_24036319_24036528
0.00526
-0.042
DataSet_01_464
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00110
-0.048
DataSet_01_464
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CDK16
47081659_47081779_47081659_47081741_47082950_47083158
0.00407
-0.412
DataSet_01_464
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CERS4
8320687_8320920_8320687_8320763_8321119_8321170
0.00768
0.09
DataSet_01_464
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CES2
66976550_66976688_66976550_66976640_66977201_66977274
0.00090
0.058
DataSet_01_464
View details
CHPT1
102120071_102120275_102120071_102120182_102122678_102122852
0.00000
0.201
DataSet_01_464
View details
CYSTM1
139554740_139554870_139554740_139554788_139574030_139574237
0.00214
-0.032
DataSet_01_464
View details
Showing 1 to 10 of 31 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI1
27047990_27048167_27047990_27048164_27054146_27054247
0.00614
0.164
DataSet_01_464
View details
AC007319.1
188419002_188419120_188419043_188419120_188412199_188412434
0.00998
0.158
DataSet_01_464
View details
AMBP
116838877_116839038_116838877_116839008_116840372_116840752
0.00145
-0.02
DataSet_01_464
View details
AP000525.9
16186810_16186953_16186810_16186946_16187164_16187302
0.00319
0.06
DataSet_01_464
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AP1G2
24031170_24031372_24031170_24031262_24031496_24031624
0.00001
-0.793
DataSet_01_464
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APOA2
161193151_161193247_161193151_161193215_161193384_161193418
0.00000
-0.033
DataSet_01_464
View details
ATP7B
52532446_52532680_52532446_52532536_52534283_52534458
0.00184
0.074
DataSet_01_464
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ATXN2L
28843507_28843720_28843525_28843720_28842282_28842393
0.00894
-0.031
DataSet_01_464
View details
C1orf63
25570040_25570715_25570040_25570124_25571640_25571792
0.00871
0.308
DataSet_01_464
View details
C2
31912954_31913449_31913238_31913449_31912561_31912806
0.00794
-0.059
DataSet_01_464
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTR1B
98274889_98275466_98274889_98275106_98275341_98275466
0.00364
-0.083
DataSet_01_464
View details
ADRBK1
67049741_67050013_67049741_67049836_67049905_67050013
0.00665
-0.059
DataSet_01_464
View details
C17orf76-AS1
16342640_16343567_16342640_16342728_16343498_16343567
0.00224
-0.011
DataSet_01_464
View details
CASC3
38319733_38320419_38319733_38319855_38320138_38320419
0.00528
0.067
DataSet_01_464
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CDK11A
1634914_1635379_1634914_1635063_1635262_1635379
0.00676
0.161
DataSet_01_464
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CDK5RAP3
46051765_46052703_46051765_46051814_46052524_46052703
0.00650
-0.103
DataSet_01_464
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CHKB
51020177_51021283_51020177_51020291_51020677_51021283
0.00858
-0.283
DataSet_01_464
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CLPTM1L
1324877_1325931_1324877_1324928_1325865_1325931
0.00231
0.137
DataSet_01_464
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CLU
27462440_27462852_27462440_27462586_27462688_27462852
0.00995
0.016
DataSet_01_464
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CRLF1
18704874_18705117_18704874_18704917_18705056_18705117
0.00089
-0.015
DataSet_01_464
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
109535117
C
T
0.00211
WDR47
-
FALSE
chr1
237064432
C
G
0.00019
MTR
+
FALSE
chr1
19543353
T
C
0.00377
LOC101927895,EMC1
+,-
FALSE
AluJb
SINE,Alu
chr1
25688276
A
G
0.00187
TMEM50A
+
FALSE
chr1
1344893
A
G
0.00186
.
FALSE
AluSg
SINE,Alu
chr1
6695423
T
G
9.25675E-05
THAP3,DNAJC11
+,-
FALSE
chr1
2522392
G
A
0.00227
FAM213B,MMEL1
+,-
FALSE
chr1
45975740
C
G
0.00096
MMACHC
+
FALSE
AluSx4
SINE,Alu
chr1
145512951
A
G
4.65248E-05
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluSz6
SINE,Alu
chr1
1252441
T
C
0.00086
CPSF3L
-
TRUE
AluJr
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression