Dataset Overview
RBPDDX6
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR147ZBD
PlatformHiSeq
Pubmed ID32252787

DDX6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr127203728AT0.00528.FALSE
chr1163116048GT3.38683E-05RGS5-FALSE
chr2219100202CT0.00027ARPC2+FALSEAluJrSINE,Alu
chr398518158AT0.00960DCBLD2-FALSE
chr116577794CT0.00805FBXO42-FALSE
chr4165998694TC0.00041TMEM192-TRUEAluSgSINE,Alu
chr11653093AG0.00642CDK11B,CDK11A-FALSEL2SINE,Alu
chr2202901910GA0.00963FZD7+FALSE
chr347628810TA0.00934SMARCC1-FALSE
chr116893763TC0.00159NBPF1-FALSE
chr413606576AT0.00737BOD1L1-FALSE
chr178378694AC0.00735MYH10-FALSE
chr116945227GT0.00090CROCCP2-FALSE
chr1150937960GC0.00014CERS2-FALSEG-richSINE,Alu
chr8101932094TA0.00288YWHAZ-FALSEMER34B-intSINE,Alu
chr2178186556GA0.00917LOC100130691-FALSE
chr1148251009TC0.00065NBPF8,NBPF14,NBPF9-TRUE
chr119199221CT0.00392ALDH4A1-FALSE
chr1765334867TC1.03096E-06PSMD12-TRUEAluSqSINE,Alu
chr1201846632CT7.46598E-05IPO9+FALSE(CA)nSINE,Alu
chr136068231TC9.19439E-05PSMB2-TRUEAluScSINE,Alu
chr644222157GA0.00856SLC35B2-FALSE
chr1220323448CT0.00223RAB3GAP2-FALSE
chr1114940216TG0.00148TRIM33-FALSE(T)nSINE,Alu
chr1591044383GT0.00440IQGAP1+FALSE
chr1028971536AT0.00815BAMBI+FALSE
chr1165877575AC0.00839UCK2+FALSE
chr131732601AT0.00175SNRNP40-FALSE
chr1168218543AG7.78857E-07.FALSEAluSzSINE,Alu
chr5125961487AG0.00776PHAX+FALSEAluSz6SINE,Alu
chr123408016CA4.80633E-05KDM1A+FALSE
chr543290210AG0.00565HMGCS1-FALSEA-richSINE,Alu
chr340353791AT0.00419EIF1B+FALSE
chr286251114TC0.00709.FALSEAluSxSINE,Alu
chr3156258319TC0.00012SSR3-TRUEAluYk3SINE,Alu
chr154692334TC5.22151E-05SSBP3-FALSE(T)nSINE,Alu
chr541917695CT0.00546C5orf51+FALSE
chr237328097TC0.00301.FALSE
chr11595604AT0.00233CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr457326156AG0.00230PAICS+TRUEAluJrSINE,Alu
chr8145159712AG0.00402MAF1+FALSE
chr13545183AT0.00347TPRG1L+FALSE
chr120976163CT0.00091PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr154355105AG0.00325YIPF1-FALSEMIRbSINE,Alu
chr111783009AG7.55078E-05.FALSEAluSxSINE,Alu
chr175196073CT0.00159CRYZ-FALSE
chr132799438AT0.00485MARCKSL1-FALSE
chr2203426264CT0.00948BMPR2+FALSE
chr2144836048GA0.00542LOC102724428,SIK1-FALSE
chr128607959CA0.00215SESN2+FALSE
chr19642827GA0.00521SLC25A33+FALSE
chr123240263GA5.22984E-05EPHB2+FALSE
chr255776561TA0.00092PPP4R3B-FALSE
chr1100490275AG0.00142SLC35A3+TRUEAluSc5SINE,Alu
chr19161203TC3.69156E-05.FALSEAluSxSINE,Alu
chr1148595665AG0.00141NBPF15+TRUEL1MC4SINE,Alu
chr140214296AG0.00485PPIE+TRUEAluSq2SINE,Alu
chr1120163247TC0.00365ZNF697-FALSE
chr1155142927AG0.00877KRTCAP2-FALSE
chr274333231CT0.00073TET3+FALSE
chr626411987TC0.00405BTN3A1+FALSE
chr543298557CT0.00643HMGCS1-FALSE
chr110517689TC0.00504.FALSEAluSx1SINE,Alu
chr1179829093TC0.00056TOR1AIP2-TRUEAluJrSINE,Alu
chr1246829616TC0.00139CNST+FALSE
chr2234775941AG0.00161MSL3P1-FALSE
chr310193796AG2.82806E-06VHL+TRUEAluSxSINE,Alu
chr146830430GA0.00023NSUN4+FALSELTR108a_MamSINE,Alu
chr111347164AC0.00667UBIAD1+FALSE
chr1230979207CA0.00643C1orf198-FALSE
chr285824712CA0.00663RNF181+FALSE
chr191486839TC0.00329ZNF644-FALSE
chr1320211AG6.69717E-05.FALSEAluJoSINE,Alu
chr119542310TC0.00112LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr425749196TA0.00870SEL1L3-FALSE
chr110517672TC0.00090.FALSEAluSx1SINE,Alu
chrX131339006TA0.00405RAP2C-FALSE
chr1590819423AG3.09408E-05.FALSEAluSxSINE,Alu
chr237328100TC0.00027.FALSE
chr237429737AG0.00439CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr13548832GC0.00464WRAP73-FALSE
chr1109812555AC3.87556E-05CELSR2+FALSE
chr124861704GA0.00345RCAN3+FALSE
chr631132911CT0.00000.FALSE
chr2204301752GC0.00029RAPH1-FALSE
chr19165685GA7.66901E-05GPR157-FALSE
chr247129284AG0.00327MCFD2-FALSE
chr5177019196GC0.00509TMED9+FALSE(GCG)nSINE,Alu
chr457326236AG0.00699PAICS+TRUEAluJrSINE,Alu
chr145975345AG0.00071MMACHC+TRUEAluSg7SINE,Alu
chr531553951CT0.00240C5orf22+FALSE
chr8124262075GT7.79989E-05ZHX1-C8orf76,ZHX1-FALSE
chr5118175329TC2.47285E-05DTWD2-TRUEAluJrSINE,Alu
chr7128143945AG0.00607.FALSEAluSq2SINE,Alu
chr1201975173GT0.00053RNPEP+FALSE
chr270316299CA0.00650PCBP1+FALSE
chr12123253789AG0.00037DENR+TRUE(AT)nSINE,Alu
chr170718280AC0.00946.FALSE
chr4160279820CT0.00354RAPGEF2+FALSE
chr2231032372AG0.00691.FALSEMLT1HSINE,Alu
chr1147124310TG0.00968ACP6-FALSE
chr1205112911TC0.00161DSTYK-FALSE
chr5175816759TA0.00018.FALSE
chr349506286GT0.00052DAG1+FALSEAluJbSINE,Alu
chr631322980CT0.00091.FALSE
chr63021492AG0.00613HTATSF1P2-FALSETigger3aSINE,Alu
chr1220231276TC0.00545RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr9128127412AG0.00751.FALSE
chr1183595345AT0.00383ARPC5-FALSE
chr125894464GA0.00527LDLRAP1+FALSEMIRbSINE,Alu
chr484525986GT0.00081GPAT3+FALSE(TTGTT)nSINE,Alu
chr136770045TC0.00488THRAP3+FALSE
chr1138156GT0.00413LOC729737-FALSE
chr2025427756AG0.00396GINS1+TRUEAluSzSINE,Alu
chr1155032752AG0.00347LOC100505666,ADAM15+,-FALSE
chr140537943AC0.00115CAP1+FALSE(A)nSINE,Alu
chr3196197477AC0.00174RNF168-FALSE
chr1200375835GT0.00063ZNF281-FALSE(T)nSINE,Alu
chr136067817TC0.00938PSMB2-TRUEAluSzSINE,Alu
chr1225683161TG0.00168ENAH-FALSE(T)nSINE,Alu
chr136068052GT1.43241E-12PSMB2-FALSEL1ME4bSINE,Alu
chr1145512078AG0.00099NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr484525974TC0.00255GPAT3+FALSE(TTGTT)nSINE,Alu
chr349067809TA0.00022QRICH1-FALSE
chr132385071TA0.00436PTP4A2-FALSE
chr178414308TC0.00024FUBP1-FALSE
chr116893691CA0.00764NBPF1-FALSE
chr1610623639TC0.00392EMP2-TRUEAluSpSINE,Alu
chr2120021785TC0.00751STEAP3+FALSE
chr4165998078TC0.00567TMEM192-TRUEAluSxSINE,Alu
chr128825466AG0.00701PHACTR4+TRUEAluSgSINE,Alu
chr357549504AG0.00384PDE12+TRUEAluJbSINE,Alu
chr3124732406CA0.00975HEG1-FALSE
chr1900505GC0.00583KLHL17+FALSE
chr4169910101CT0.00026CBR4-FALSE
chr136068325TC3.42972E-06PSMB2-TRUEAluScSINE,Alu
chr195658346TA0.00098TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr2191745653TG0.00030GLS+FALSE
chr1951305796TC0.00212C19orf48-TRUEAluSgSINE,Alu
chr371005566CT0.00209FOXP1-FALSE(T)nSINE,Alu
chr1160966351TC0.00023F11R-TRUEAluSgSINE,Alu
chr456294628TC0.00234CLOCK-FALSE
chr45830393CT0.00220CRMP1-FALSE
chr156961756AG0.00263PLPP3-FALSE
chr1423795219CT0.00201BCL2L2-PABPN1,PABPN1+FALSE
chr590074268GA0.00240ADGRV1+FALSE
chr1167759281TC0.00923MPZL1+FALSE
chr1205501469AG0.00113CDK18+FALSE
chr1204521580AG0.00169MDM4+TRUEAluSgSINE,Alu
chr110520532TC0.00013.FALSEAluSx1SINE,Alu
chr138326661TC0.00023INPP5B-TRUEAluJrSINE,Alu
chr1158067059AC0.00655KIRREL+FALSE
chr116932783GC0.00843NBPF1-FALSEL1MC2SINE,Alu
chr146077345AG0.00024NASP+TRUEAluSc8SINE,Alu
chr1179829200TC0.00497TOR1AIP2-TRUEAluJrSINE,Alu
chr841399912CA0.00056LOC102723729,GINS4+,-FALSEAluSx3SINE,Alu
chr438016395TG0.00537TBC1D1+FALSE
chr11164179GA0.00983SDF4-FALSEG-richSINE,Alu
chr2218571431AG0.00158PEX26+TRUEAluSzSINE,Alu
chr194353045GT0.00351GCLM-FALSEAluSgSINE,Alu
chr1958375707AG0.00156ZNF587+TRUEAluSgSINE,Alu
chr1591044387TG0.00077IQGAP1+FALSE
chr19328213AG5.00055E-05H6PD+TRUEAluJrSINE,Alu
chr128661657AG0.00910MED18+TRUEAluSgSINE,Alu
chr131732603AC0.00148SNRNP40-FALSE
chr1741144609GA0.00821RUNDC1+FALSE
chr8144940794GC0.00038EPPK1-FALSE
chr332567573GA0.00320DYNC1LI1-FALSE(AT)nSINE,Alu
chr2203741654TC0.00611.FALSEAluJrSINE,Alu
chr6160100882TC3.93365E-05SOD2-TRUEAluSzSINE,Alu
chr3120115286TG0.00077FSTL1-FALSE
chr3156259229TC1.62025E-06SSR3-TRUEAluSq2SINE,Alu
chr29629953CA0.00105ADAM17-FALSE
chr45743512TC0.00210EVC+FALSE
chr1193054154GA0.00757TROVE2+FALSE
chr2201774342TC0.00127.FALSEAluSzSINE,Alu
chr1918477761AG0.00461PGPEP1+TRUEAluJbSINE,Alu
chr3191111160AG4.43846E-07CCDC50+FALSE
chr136067752TC0.00031PSMB2-TRUEAluSzSINE,Alu
chr9124103030GA0.00193STOM-FALSEAluSq2SINE,Alu
chr448854139TC0.00133OCIAD1+FALSEL2cSINE,Alu
chr146078630AG0.00131NASP+FALSE
chr136067886TC0.00786PSMB2-TRUEAluSzSINE,Alu
chr270504926AG0.00671PCYOX1+FALSEMER5ASINE,Alu
chr42940364TC0.00718NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr16694574GA0.00983THAP3,DNAJC11+,-FALSE
chr11234671GA0.00100ACAP3-FALSE
chr128836975AG0.00782SNHG3,RCC1+TRUEAluScSINE,Alu
chr312940374TG0.00505IQSEC1-FALSE
chr2140567665GA0.00786BRWD1-FALSE
chr138275432GT0.00057MTF1-FALSE
chr114150032CT0.00163PRDM2+FALSE
chr12125512507AG0.00276.FALSEAluYSINE,Alu
chr136068369TC0.00404PSMB2-TRUEAluScSINE,Alu
chr1113212976CT0.00904CAPZA1+FALSE
chr1145100772AG0.00945NBPF20,SEC22B+TRUEAluSg4SINE,Alu
chr112401868AC0.00526VPS13D+FALSE
chr717384440AG0.00271AHR+TRUEAluSxSINE,Alu
chr921863621CA0.00123MTAP+FALSEAluYSINE,Alu
chr1204521239AG0.00095MDM4+TRUEAluSpSINE,Alu
chr226613948AG0.00218EPT1+FALSE
chr347386062TA4.63678E-05KLHL18+FALSE
chr1949608GA0.00435ISG15+FALSE
chr344790781TC0.00887KIAA1143-TRUEAluYSINE,Alu
chr10101992793TC0.00407CWF19L1-TRUEAluJbSINE,Alu
chr2202252539GA0.00293TRAK2-FALSE
chr748146025AG0.00106UPP1+TRUEAluSqSINE,Alu
chr116893813AG7.34801E-05NBPF1-FALSE
chr1144918957TA0.00484NBPF20,PDE4DIP+,-FALSE
chr239009425AG0.00607.FALSEAluSx3SINE,Alu
chr398299365TG0.00133CPOX-FALSE
chr11152309AT0.00035SDF4-FALSE
chr316357708AG0.00098RFTN1-FALSE
chr119585493AG3.52757E-05MRTO4+TRUEAluSc8SINE,Alu
chr393846831GA0.00547.FALSEAluSq2SINE,Alu
chr145975574AG0.00613MMACHC+TRUEAluSx4SINE,Alu
chr1142619386GA0.00637.FALSE
chr2202028727AG0.00833CFLAR+TRUEAluSx1SINE,Alu
chr29558812GT0.00427ITGB1BP1-FALSE
chr1900723TG0.00051KLHL17+FALSE(TTTA)nSINE,Alu
chr119953120GA0.00025MINOS1,MINOS1-NBL1+FALSE
chr1745761101GT0.00296.FALSE
chr1155695960AG1.11424E-05DAP3+TRUEAluSpSINE,Alu
chr3196078364GA0.00290.FALSEGA-richSINE,Alu
chr1144053567CT0.00353.FALSE
chr457326291AG0.00549PAICS+TRUEAluJrSINE,Alu
chr1431916792CT3.89824E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr296850885TC0.00699STARD7-FALSE
chr1121133733GA0.00455SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr1109818270CT0.00996CELSR2+FALSE
chr1157963370CG0.00445KIRREL+FALSE
chr11490771CT0.00600PTDSS2+FALSE
chr572801321TA0.00427BTF3+FALSE
chr11650797AG3.70820E-05CDK11B,CDK11A-FALSE
chr672012435AG0.00723OGFRL1+FALSEAluSgSINE,Alu
chr7156764350GC0.00415NOM1+FALSE
chr136067677TC1.65353E-05PSMB2-TRUEAluSzSINE,Alu
chr1234561498TC2.33971E-05TARBP1-FALSE
chr126449336AG0.00343PDIK1L+FALSE
chrX123045103AG0.00996XIAP+TRUEAluSpSINE,Alu
chr1450361170CT0.00096ARF6+FALSE(T)nSINE,Alu
chr140537940AC0.00155CAP1+FALSE(A)nSINE,Alu
chr3194998813AG0.00572ACAP2-FALSEAluSx1SINE,Alu
chr264863970CT9.52027E-09SERTAD2-FALSE
chr633384325GT0.00456.FALSE
chr1154554940GC0.00032ADAR-FALSE
chr1193474585TG0.00531TAF1D-FALSE
chr237328097TC3.71887E-07.FALSE
chr3194362721GA5.25740E-07LSG1-FALSE
chr10101992783TC0.00313CWF19L1-TRUEAluJbSINE,Alu

Differential Expression Gene Analysis