Dataset Overview
RBP
DDX6
Knock-Method
shRNA
RBP Family
DEAD
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR147ZBD
Platform
HiSeq
Pubmed ID
32252787
DDX6 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of DDX6
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
40.38
29.69
-0.39676
3.10541E-05
6.77059E-05
A1CF
29.02
22.49
-0.88481
1.56418E-23
1.22396E-22
A2M
2827.98
3851.15
0.47882
4.25131E-08
1.24730E-07
A4GALT
0.16
6.14
5.21208
1.11713E-90
6.56969E-89
AAAS
21.26
13.79
-0.59426
3.97717E-09
1.27950E-08
AACS
17.52
14.38
-0.27626
0.00144
0.00255
AADAT
2.45
1.14
-1.15192
1.65338E-07
4.57115E-07
AAGAB
4.83
8.64
0.89794
4.56375E-15
2.27620E-14
AAK1
1.2
3.09
1.65799
1.52187E-24
1.24922E-23
AAMDC
27.35
31.28
0.29787
0.03406
0.04875
Showing 1 to 10 of 9,531 entries
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Function Analysis of Target Genes of DDX6
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101556531_101556610_101554169_101554225_101556853_101557853
0.00563
0.093
DataSet_01_469
View details
ABI1
27044583_27044670_27040526_27040712_27047990_27048167
0.00293
-0.179
DataSet_01_469
View details
ABI2
204276007_204276094_204267298_204267457_204281630_204281804
0.00638
-0.141
DataSet_01_469
View details
ACADSB
124797262_124797363_124793870_124794031_124799981_124800173
0.00807
-0.077
DataSet_01_469
View details
ADH6
100128602_100128738_100125878_100126220_100129824_100130085
0.00651
-0.192
DataSet_01_469
View details
AHSG
186337645_186337863_186336324_186336426_186338374_186339107
0.00000
0.02
DataSet_01_469
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AHSG
186337645_186337714_186336300_186336426_186338374_186339107
0.00001
0.022
DataSet_01_469
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AHSG
186336079_186336280_186334975_186335139_186338374_186338579
0.00004
-0.196
DataSet_01_469
View details
AHSG
186336079_186336280_186334975_186335139_186337645_186337729
0.00015
-0.237
DataSet_01_469
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AKR1C2
5045017_5045264_5043705_5043873_5045943_5046215
0.00001
0.203
DataSet_01_469
View details
Showing 1 to 10 of 243 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACP1
272036_272150_272191_272305_271865_271939
0.00000
0.107
DataSet_01_469
View details
ACP1
272036_272150_272191_272305_271865_271939
0.00011
0.097
DataSet_01_469
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ACSS3
81532909_81533044_81536885_81537026_81528594_81528783
0.00000
-0.24
DataSet_01_469
View details
AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00005
-0.01
DataSet_01_469
View details
AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00005
-0.154
DataSet_01_469
View details
AHSG
186336300_186336426_186337645_186337863_186334975_186335139
0.00029
-0.117
DataSet_01_469
View details
AHSG
186336285_186336426_186337645_186337863_186334975_186335139
0.00034
-0.123
DataSet_01_469
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AHSG
186336351_186336426_186337645_186337863_186334975_186335139
0.00073
-0.122
DataSet_01_469
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AHSG
186336079_186336280_186337645_186337714_186334975_186335139
0.00294
-0.13
DataSet_01_469
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AHSG
186336285_186336426_186337645_186337714_186334975_186335139
0.00374
-0.106
DataSet_01_469
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Showing 1 to 10 of 110 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AHSA2
61411846_61412059_61411846_61411935_61412636_61412753
0.00765
0.019
DataSet_01_469
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ARMC10
102724128_102724509_102724128_102724277_102727076_102727211
0.00316
-0.098
DataSet_01_469
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BPIFB2
31602431_31602621_31602431_31602453_31603241_31603302
0.00721
0.082
DataSet_01_469
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CALD1
134617738_134618828_134617738_134618141_134620438_134620516
0.00694
-0.169
DataSet_01_469
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CUL7
43019850_43020534_43019946_43020534_43019349_43019501
0.00308
0.114
DataSet_01_469
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DUS4L
107214148_107214328_107214148_107214266_107215632_107215755
0.00138
-0.218
DataSet_01_469
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GMPR2
24702158_24702266_24702158_24702183_24702424_24702546
0.00358
-0.079
DataSet_01_469
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HAAO
43019423_43019671_43019596_43019671_43015668_43015747
0.00805
0.5
DataSet_01_469
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HINT3
126277926_126278324_126277926_126278034_126288032_126288150
0.00986
0.133
DataSet_01_469
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HNRNPH1
179044051_179044111_179044060_179044111_179043881_179043959
0.00058
-0.02
DataSet_01_469
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Showing 1 to 10 of 30 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC040977.1
6915927_6916096_6915927_6916076_6916984_6917062
0.00019
0.065
DataSet_01_469
View details
AC040977.1
6915927_6916080_6915927_6916076_6916984_6917062
0.00019
0.056
DataSet_01_469
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AP1G2
24033254_24033430_24033254_24033368_24033541_24033590
0.00636
0.15
DataSet_01_469
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APOA1
116707794_116707865_116707794_116707827_116708060_116708141
0.00006
-0.367
DataSet_01_469
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APOA1
116707794_116707843_116707794_116707827_116708060_116708141
0.00016
-0.267
DataSet_01_469
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APOA2
161192707_161192820_161192707_161192784_161193139_161193215
0.00613
0.049
DataSet_01_469
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ASPSCR1
79970031_79970159_79970106_79970159_79969418_79969481
0.00267
0.034
DataSet_01_469
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ATP5G2
54063654_54063898_54063654_54063732_54066359_54066429
0.00236
0.012
DataSet_01_469
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AUP1
74754067_74754272_74754067_74754186_74754374_74754446
0.00839
0.026
DataSet_01_469
View details
BAG6
31611858_31612004_31611858_31611971_31612301_31612379
0.00635
-0.077
DataSet_01_469
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38167652_38168191_38167652_38167832_38168000_38168191
0.00231
-0.075
DataSet_01_469
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ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00943
-0.014
DataSet_01_469
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ATP6V0B
44442697_44443967_44442697_44442888_44443652_44443967
0.00002
-0.051
DataSet_01_469
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AUP1
74755877_74756409_74755877_74756062_74756258_74756409
0.00678
-0.052
DataSet_01_469
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C17orf76-AS1
16342640_16343567_16342640_16343017_16343498_16343567
0.00000
-0.039
DataSet_01_469
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C1orf63
25570040_25571792_25570040_25570124_25571640_25571792
0.00003
-0.363
DataSet_01_469
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CAPN1
64978284_64979476_64978284_64978343_64978730_64979476
0.00089
0.047
DataSet_01_469
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CD46
207940357_207943707_207940357_207940540_207943665_207943707
0.00003
-0.117
DataSet_01_469
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CDK5RAP3
46051765_46052703_46051765_46051814_46052524_46052703
0.00550
-0.111
DataSet_01_469
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CENPT
67863667_67864451_67863667_67863991_67864292_67864451
0.00567
-0.184
DataSet_01_469
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
27203728
A
T
0.00528
.
FALSE
chr1
163116048
G
T
3.38683E-05
RGS5
-
FALSE
chr1
16577794
C
T
0.00805
FBXO42
-
FALSE
chr1
1653093
A
G
0.00642
CDK11B,CDK11A
-
FALSE
L2
SINE,Alu
chr1
16893763
T
C
0.00159
NBPF1
-
FALSE
chr1
16945227
G
T
0.00090
CROCCP2
-
FALSE
chr1
150937960
G
C
0.00014
CERS2
-
FALSE
G-rich
SINE,Alu
chr1
148251009
T
C
0.00065
NBPF8,NBPF14,NBPF9
-
TRUE
chr1
19199221
C
T
0.00392
ALDH4A1
-
FALSE
chr1
201846632
C
T
7.46598E-05
IPO9
+
FALSE
(CA)n
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression