Dataset Overview
RBPPRPF6
Knock-MethodshRNA
RBP FamilyPRP1_N
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR529QEZ
PlatformHiSeq
Pubmed ID32252787

PRPF6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PRPF6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PRPF6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1450792966AT0.00852.FALSEAluSxSINE,Alu
chr11595603CG0.00017CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr744841237TA0.00599PPIA+FALSE
chr136067760TC0.00044PSMB2-TRUEAluSzSINE,Alu
chr811701429TC0.00758CTSB-TRUEAluSx1SINE,Alu
chr1171509327GA0.00110PRRC2C+FALSE
chr285548074TC0.00724TGOLN2-FALSE
chr1269237020AG0.00378MDM2+TRUE
chr349395693CG0.00243GPX1-FALSE(GCC)nSINE,Alu
chr7286402AG1.78989E-09FAM20C+FALSE
chr1145291108AC0.00827NBPF20+FALSE
chr110519936TC0.00607.FALSEAluJrSINE,Alu
chr179109337GT0.00790IFI44L+FALSELTR26SINE,Alu
chr1142804438GT0.00618.FALSE
chr125570561TA0.00425RSRP1-FALSEAluSINE,Alu
chr2120022385CT0.00184STEAP3+FALSE
chr652860746TG0.00011.FALSE7SKSINE,Alu
chr347386062TA4.63678E-05KLHL18+FALSE
chr1467852040AG4.57409E-05EIF2S1+TRUEAluJbSINE,Alu
chr116932144AC0.00559NBPF1-FALSE
chr11344757AG0.00024.FALSEAluSx1SINE,Alu
chr110518831TC0.00410.FALSEAluSx1SINE,Alu
chr1206581246TC0.00210SRGAP2+FALSE
chr136320634TC0.00190AGO4+FALSE
chr132373858AT0.00100PTP4A2-FALSE
chr117734207GA0.00020RCC2-FALSE
chr1541593308AG0.00619.FALSEAluSz6SINE,Alu
chr1272096335AG1.07858E-05TMEM19+FALSEAluSz6SINE,Alu
chr133148216AG0.00321SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr2224844864AG7.12020E-05SERPINE2-FALSEL2bSINE,Alu
chr237331107TC0.00020.FALSEAluSx1SINE,Alu
chr153288894AG0.00066ZYG11B+TRUEAluJoSINE,Alu
chr227293352AT0.00314AGBL5,OST4+,-FALSE
chr166099013CA7.87351E-06LEPR+FALSE
chr1145281656AT0.00768NBPF20,NOTCH2NL+FALSE
chr299772813AG0.00670LIPT1+TRUEAluSx1SINE,Alu
chr166100450GA0.00528LEPR+FALSE
chr1116235186AG0.00054VANGL1+FALSE
chr2176791183TC0.00252LNPK-TRUEMSTDSINE,Alu
chr140539212CA0.00380PPT1-FALSE
chr1256510697GA0.00055RPL41+FALSE
chr1152884247AG0.00642IVL+FALSE
chr11718810GA5.85228E-05GNB1-FALSE
chr9124094999GT0.00764GSN+FALSE(TG)nSINE,Alu
chr19324451CT0.00266H6PD+FALSE
chr894744813CT5.22032E-05RBM12B-FALSE
chr1109535128GA0.00063WDR47-FALSE
chr1094414146AG0.00911KIF11+FALSE
chr2234385276TC0.00951USP40-FALSE
chr1179042905AG0.00972FAM20B+TRUE
chr2187544230TA0.00930ITGAV+FALSE
chr11118661811TG0.00582DDX6-FALSE
chr11717439TA0.00663GNB1-FALSE
chr46644459CA0.00109MRFAP1+FALSE
chr1063852210CT0.00324ARID5B+FALSE
chr9115447535TC3.15593E-07INIP-TRUEAluJbSINE,Alu
chr347125385GA0.00496SETD2-FALSE
chr1476680377TA0.00143.FALSEL1M5SINE,Alu
chr2219433597GA0.00328CNOT9+FALSE
chr9115446668TC1.81109E-05INIP-TRUEAluJrSINE,Alu
chr119499560TC0.00100UBR4-FALSE
chr298272734AG0.00996ACTR1B-FALSE
chr77283569GA0.00032C1GALT1+FALSE(AT)nSINE,Alu
chr3196729939CT0.00862MELTF,MFI2-AS1+,-FALSEG-richSINE,Alu
chr116861718CT0.00891LOC100132147-FALSE
chr968413593CA0.00342.FALSE
chr237328016TC5.08368E-07.FALSE
chr140705200GA3.20116E-08RLF+FALSE
chr1917412218CT0.00790ABHD8-FALSE
chr1179042692AG4.94937E-05FAM20B+TRUEAluSx1SINE,Alu
chr1419684445AG0.00351DUXAP10+FALSE
chr1214529725TC0.00535PTPN14-TRUE
chr145975673AG0.00410MMACHC+TRUEAluSx4SINE,Alu
chr3122291688AG0.00597DTX3L+FALSEAluSzSINE,Alu
chr9136209396CT0.00126MED22-FALSE
chr76063466TA0.00153EIF2AK1-FALSE
chr2197184321CT0.00923HECW2-FALSE
chr132661578CT0.00694TXLNA+FALSE(T)nSINE,Alu
chr136386884CT0.00590AGO1+FALSE
chr1101443701AG0.00749SLC30A7+FALSE
chr5149363414AG0.00503SLC26A2+TRUEAluJrSINE,Alu
chr4103718454TA0.00446LOC102723704,UBE2D3+,-FALSE
chr116891365GA0.00609NBPF1-FALSE
chr16583538TC0.00455NOL9-TRUEAluSqSINE,Alu
chr1155695968AG0.00017DAP3+TRUEAluSpSINE,Alu
chr147844403CA0.00511CMPK1+FALSE
chr2206986245TC0.00979.FALSEAluSzSINE,Alu
chr13545192CG0.00332TPRG1L+FALSE
chr8144940222AC0.00202EPPK1-FALSE
chr637138022CG0.00953PIM1+FALSE
chr237330172TG0.00972.FALSE
chr125717365CG0.00229RHCE-FALSE
chr5125962354AG3.71532E-05PHAX+TRUEAluScSINE,Alu
chr133148623AG0.00221SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1212967264CG0.00781DDX47+FALSE
chr167874697TC0.00022SERBP1-TRUEAluSx3SINE,Alu
chr153680090GA0.00321C1orf123-FALSE
chr1145369589TC0.00046NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr63021465TC0.00029HTATSF1P2-TRUEAluJr4SINE,Alu
chr16932082TA0.00330CAMTA1+FALSE
chr119411087CT0.00226UBR4-FALSE
chr398518158AT0.00960DCBLD2-FALSE
chr120238574CT6.32696E-05OTUD3+FALSE
chr439550612TC0.00023UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1145513112AG0.00080NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr264119873AT0.00492VPS54-FALSE
chr1921302035AG5.57890E-05ZNF714+TRUEAluSg4SINE,Alu
chr1109818151TC0.00855CELSR2+FALSE
chr1610625101TC0.00804EMP2-TRUEAluSx3SINE,Alu
chr2206981832TC0.00251.FALSEAluJbSINE,Alu
chr1160966352TC3.14235E-07F11R-TRUEAluSgSINE,Alu
chr110519946TC0.00578.FALSEAluJrSINE,Alu
chr310290515GA0.00904TATDN2+FALSE
chr146828460CT0.00101NSUN4+FALSE
chr1154315369CT0.00022ATP8B2+FALSE
chr1569803GA0.00695.FALSE
chr1773702478GC8.31704E-05SAP30BP+FALSE
chr224223159AG0.00717UBXN2A+TRUEAluScSINE,Alu
chr2170497653TG0.00587.FALSE
chr125570563AT0.00276RSRP1-FALSEAluSINE,Alu
chr1146400122CG0.00190NBPF20,NBPF10,NBPF25P,NBPF12+FALSE
chr119542463TC0.00182LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr6138413269AG0.00743PERP-FALSE
chr116891340TA0.00404NBPF1-FALSE
chr1542861741AG0.00200HAUS2+TRUEAluJbSINE,Alu
chr826435508CT0.00106DPYSL2+FALSE(TC)nSINE,Alu
chr133148736AG0.00849SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr11252349AG0.00798CPSF3L-FALSEAluJrSINE,Alu
chr116921146TC0.00039NBPF1-FALSE
chr1765335430TC0.00019PSMD12-TRUEAluSxSINE,Alu
chr356763328TC0.00546ARHGEF3-FALSE
chr570248476TG0.00273SMN1,SMN2+FALSEL1MC5aSINE,Alu
chr596350710GA0.00302LNPEP+FALSE
chr891637754AT0.00297TMEM64-FALSE
chr126144433TC0.00476SEPN1+FALSE
chr653363500GT0.00684GCLC-FALSE
chr642045545AG0.00440TAF8+TRUEAluSzSINE,Alu
chr6111588769AG2.24603E-05MFSD4B+TRUEAluYm1SINE,Alu
chr119586519AG0.00239MRTO4+TRUEAluSzSINE,Alu
chr7129472357AG0.00287UBE2H-FALSE
chr1205057482AT0.00907RBBP5-FALSE
chr5125961648AG0.00031PHAX+FALSEAluSz6SINE,Alu
chr6122765962TA0.00362SERINC1-FALSE
chr236776056TA0.00030CRIM1+FALSE
chr1138156GT0.00048LOC729737-FALSE
chr1148252785TC0.00314NBPF8,NBPF14,NBPF9-FALSE
chr310193796AG2.82806E-06VHL+TRUEAluSxSINE,Alu
chr126143728CT0.00800SEPN1+FALSEAluSxSINE,Alu
chr192862862AG0.00024.FALSEAluJrSINE,Alu
chr1226923264GA0.00046ITPKB-FALSE
chr43514539GA6.66134E-16LRPAP1-FALSE
chr296573123CT0.00413ANKRD36C-FALSE
chr11246979GT0.00168PUSL1,CPSF3L+,-FALSE
chr133147915AG6.77632E-09SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr332567573GA0.00320DYNC1LI1-FALSE(AT)nSINE,Alu
chr5176883676AT0.00456DBN1-FALSE(A)nSINE,Alu
chr217942775TA0.00367GEN1+FALSE
chr42943361TC7.19955E-07NOP14-AS1,NOP14+,-FALSE
chr4113198883GT0.00905TIFA-FALSE
chr167874859TC1.49998E-05SERBP1-TRUEAluSxSINE,Alu
chr1919791276AG0.00069ZNF101+TRUEAluSq2SINE,Alu
chr211728089CT0.00352GREB1+FALSEAluSzSINE,Alu
chr1143398850GT0.00639.FALSE
chr7137561077CA0.00995CREB3L2-FALSE
chr1144931727GA0.00521NBPF20,PDE4DIP+,-FALSE
chr110517314TC0.00368.FALSEAluJrSINE,Alu
chr1145368837CA4.93702E-07NBPF20,NBPF10+FALSE
chr1100361925GA0.00181AGL+FALSE
chr12133298423AG2.89213E-13PGAM5+TRUEAluSpSINE,Alu
chr3176739159AC0.00304TBL1XR1-FALSE
chr13111301048TC0.00037CARS2-FALSE
chr2238005476CT0.00456COPS8+FALSE
chrX123046757AG0.00535XIAP+TRUEAluSzSINE,Alu
chr1745195951TC0.00011CDC27-TRUEMADE1SINE,Alu
chr1475202373AG0.00019FCF1+FALSEAluScSINE,Alu
chr138327545TC0.00602INPP5B-TRUEAluSx3SINE,Alu
chr16582221TC0.00169NOL9-TRUEAluSq4SINE,Alu
chr1160967857TC0.00806F11R-TRUEAluSpSINE,Alu
chr72473747AG0.00872CHST12+FALSE(CCGC)nSINE,Alu
chr357542173CT0.00020PDE12+FALSE
chr19161357TC0.00739.FALSEAluSxSINE,Alu
chr237331555TC0.00171.FALSEAluJbSINE,Alu
chr136770045TC0.00943THRAP3+FALSE
chr176229185TA0.00280ACADM+FALSE
chr1180247474TC0.00022.FALSE
chr147142538GA7.23026E-06EFCAB14-AS1,EFCAB14+,-FALSE
chr887485483GC0.00554RMDN1-FALSE
chr1214524496TC0.00114PTPN14-TRUEAluSgSINE,Alu
chr237327590TC0.00364.FALSE
chr115993514CT6.34808E-08.FALSEAluSx4SINE,Alu
chr4140394600GA0.00950RAB33B+FALSE
chr1228881190TG0.00043RHOU+FALSE
chr310193475AG0.00295VHL+TRUEAluJrSINE,Alu
chr1145512937AG1.47906E-06NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1225974614AG0.00209SRP9+TRUEAluJrSINE,Alu
chr285773494TC0.00099GGCX-TRUEAluYSINE,Alu
chr1765334767TC3.33546E-08PSMD12-TRUEAluSqSINE,Alu
chr131732514CT0.00588SNRNP40-FALSE
chr116933753GA0.00609NBPF1-FALSEGA-richSINE,Alu
chr128930023GA0.00037TAF12-FALSE
chr1541593269AG0.00196.FALSEAluSz6SINE,Alu
chr1466209686TA7.37485E-06FUT8+FALSE(TT)nSINE,Alu
chr189447868GT0.00236KYAT3,RBMXL1-FALSE
chr572801329TA0.00073BTF3+FALSE
chr989626839TG0.00016LOC440173-FALSE
chr1951172526GC0.00276SHANK1-FALSE
chr164095111AG0.00201PGM1+FALSE
chr629912348AG0.00429.FALSE
chr744841239TA0.00199PPIA+FALSE
chr126801731GT0.00325HMGN2+FALSE(T)nSINE,Alu
chr110521238TC0.00232DFFA-TRUEAluYSINE,Alu
chr642856158AG0.00118RPL7L1+TRUEAluSzSINE,Alu
chr154231849CT0.00812NDC1-FALSE
chr117287301AG0.00104CROCC+FALSE
chr1145688961AG0.00324NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr224225554AG0.00419.FALSEAluSq2SINE,Alu
chr356703746AC0.00017FAM208A-FALSE
chr1161932324AG0.00056ATF6+FALSE
chr110042937AG2.41028E-05NMNAT1+TRUEAluScSINE,Alu
chr116933625AG0.00536NBPF1-FALSEGA-richSINE,Alu
chr1182809019GA0.00274DHX9+FALSE
chr126449341AG0.00622PDIK1L+FALSE
chr1201350983CT0.00768LAD1-FALSE
chr119953120GA0.00025MINOS1,MINOS1-NBL1+FALSE
chr226613949AG0.00669EPT1+FALSE
chr42940430TC2.47251E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr11118888992CG0.00222RPS25-FALSE
chr177124772GA0.00175ACADVL+FALSE
chr416258050CT0.00617TAPT1-AS1+FALSE
chr356703746AC0.00027FAM208A-FALSE
chr140214333AG0.00112PPIE+TRUEAluSq2SINE,Alu
chr177482018CA9.29146E-05SENP3-EIF4A1,EIF4A1+FALSE
chr579277950CA0.00037MTX3-FALSE(AC)nSINE,Alu
chr1015120278TC0.00018ACBD7-TRUEL1PA7SINE,Alu
chr310192596AG7.92003E-05VHL+TRUEAluSx1SINE,Alu
chr119953120GA0.00027MINOS1,MINOS1-NBL1+FALSE
chr1120612154CG0.00803NOTCH2-FALSE
chr128662253AG0.00187MED18+TRUEAluSq2SINE,Alu
chr417804785TC0.00083DCAF16-TRUEAluSxSINE,Alu
chr1921366997AG0.00727ZNF431+TRUEAluScSINE,Alu
chr340503561AT0.00012RPL14+FALSE
chr2128064448GT0.00637MAP3K2-FALSE(GT)nSINE,Alu
chr1715434181TC0.00011TVP23C-CDRT4,TVP23C-TRUEAluJbSINE,Alu
chr1144607387GC0.00016NBPF20+FALSE
chr285776987TA0.00059GGCX-FALSE
chr121766762CG0.00259NBPF3+FALSE
chr128825337AG0.00313PHACTR4+TRUEAluSgSINE,Alu
chr116892913AG0.00441NBPF1-FALSE
chr362282908CT0.00281PTPRG-AS1-FALSE
chr233007710CT0.00743TTC27+FALSE
chr12133298917AG0.00612PGAM5+TRUEAluSgSINE,Alu
chr1144874815TC0.00701NBPF20,PDE4DIP+,-FALSE
chr152816691TC0.00353CC2D1B-TRUEAluSx1SINE,Alu
chr1145281613CA0.00979NBPF20,NOTCH2NL+FALSE
chr1089623858GC0.00086PTEN+FALSE(CGG)nSINE,Alu
chr116411935TC0.00905SMPD1+FALSE(CTGGCG)nSINE,Alu
chr1911257673TC0.00155SPC24-TRUEAluSpSINE,Alu
chr133960062AG0.00437ZSCAN20+FALSE
chr1145281543CT0.00028NBPF20,NOTCH2NL+FALSE
chr116889866GA0.00995NBPF1-FALSE
chr1144053567CT0.00353.FALSE
chr120976078TC0.00064PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr310192596AG9.40892E-06VHL+TRUEAluSx1SINE,Alu
chr211321880CT0.00064ROCK2-FALSEAluSx1SINE,Alu
chr110520487TC0.00559.FALSEAluSx1SINE,Alu
chr110093371CT0.00264UBE4B+FALSE
chr178414329GA0.00922FUBP1-FALSEA-richSINE,Alu
chr1918475303AG0.00757PGPEP1+TRUEAluSx1SINE,Alu
chr2206983797TC0.00145.FALSEAluSxSINE,Alu
chr124086788CT0.00040TCEB3+FALSE
chr1212277616CT0.00248DTL+FALSE
chr822111410AG0.00396.FALSEAluSzSINE,Alu
chr110520202TC0.00825.FALSEAluSxSINE,Alu
chr1246714587GA0.00150TFB2M-FALSE
chr110517672TC0.00070.FALSEAluSx1SINE,Alu
chr3124732407TG0.00405HEG1-FALSE
chr46710356TC0.00046MRFAP1L1-FALSE
chr629910586GA1.69263E-05.FALSE
chr2201774341TC0.00073.FALSEAluSzSINE,Alu
chr1075009720TC0.00016DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr317202334AC0.00770TBC1D5-FALSE
chr131905887AC0.00245SERINC2+FALSE
chr1467852067AG2.77652E-05EIF2S1+TRUEAluJbSINE,Alu
chr765619242AG0.00545CRCP+TRUEAluSz6SINE,Alu
chr470707440TC0.00059SULT1E1-FALSEAluJrSINE,Alu
chr1541597484AG0.00619.FALSEAluSz6SINE,Alu
chr315114306TC0.00036RBSN-TRUEAluYSINE,Alu
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr417804279GA0.00606DCAF16-FALSE(A)nSINE,Alu
chr11361641CT0.00928TMEM88B+FALSE
chr1144931101GA0.00012NBPF20,PDE4DIP+,-FALSE
chr1611929653CT0.00333RSL1D1-FALSELTR14BSINE,Alu
chr12133635613TC0.00805.FALSE
chr190048248CT3.54659E-05LRRC8B+FALSE
chr1153909069GC5.11201E-05DENND4B-FALSE
chr2197021372TA0.00285STK17B-FALSE
chr16582470TC0.00370NOL9-TRUEAluSx1SINE,Alu
chr16283296TC0.00106ICMT-TRUEAluSx3SINE,Alu
chr264860431TG0.00213SERTAD2-FALSE
chr2140567667AG0.00658BRWD1-FALSE
chr8145159718GC0.00409MAF1+FALSE
chr457796757GA0.00011REST+FALSE
chr16747230CG0.00269FBXL16-FALSE
chr3197611048AG0.00064.FALSEAluSx1SINE,Alu

Differential Expression Gene Analysis