Dataset Overview
RBP
PRPF6
Knock-Method
shRNA
RBP Family
PRP1_N
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR529QEZ
Platform
HiSeq
Pubmed ID
32252787
PRPF6 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of PRPF6
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
29.34
32.14
0.18264
0.01448
0.03278
A2M
2342.22
1801.22
-0.50734
3.78886E-12
5.07051E-11
AACS
15.41
12.93
-0.38981
3.82260E-05
0.00017
AADAT
6.38
9.39
0.46947
3.20298E-05
0.00014
AAGAB
9.04
13.97
0.63999
3.70692E-09
3.30709E-08
AAK1
2.94
3.73
0.37365
0.00408
0.01092
AARS
40.96
50.38
0.22159
0.00261
0.00736
AASS
9.93
19.64
0.88070
2.61236E-22
9.28227E-21
AATK
2.01
1.33
-0.48327
0.00760
0.01871
ABAT
27.87
64.79
1.12921
2.65482E-56
6.65658E-54
Showing 1 to 10 of 7,109 entries
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Function Analysis of Target Genes of PRPF6
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101601723_101601850_101595900_101596047_101603555_101603657
0.00166
-0.039
DataSet_01_470
View details
ABCD4
74759856_74759982_74759450_74759572_74761850_74761901
0.00713
-0.276
DataSet_01_470
View details
ABCD4
74759856_74760013_74759450_74759572_74761850_74761901
0.00758
-0.27
DataSet_01_470
View details
AC027612.6
91842945_91843023_91805185_91806180_91843393_91843404
0.00085
-0.086
DataSet_01_470
View details
ACADSB
124797262_124797363_124793870_124794031_124799981_124800173
0.00557
0.028
DataSet_01_470
View details
ACSL3
223765391_223765498_223725651_223725976_223773450_223773754
0.00000
-0.216
DataSet_01_470
View details
ACSL3
223752547_223752606_223725651_223725976_223773450_223773868
0.00000
-0.079
DataSet_01_470
View details
ACSL3
223765391_223765498_223752547_223752606_223773450_223773754
0.00000
-0.128
DataSet_01_470
View details
ACSL3
223791734_223791922_223789173_223789313_223793579_223793654
0.00098
-0.563
DataSet_01_470
View details
ACSL4
108934231_108934360_108926364_108926601_108939372_108939425
0.00025
0.103
DataSet_01_470
View details
Showing 1 to 10 of 395 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC3
48734062_48734188_48734406_48734544_48733192_48733369
0.00145
-0.187
DataSet_01_470
View details
ABCD4
74759856_74759951_74761850_74761901_74759450_74759572
0.00518
0.17
DataSet_01_470
View details
ACSL3
223752547_223752606_223765391_223765498_223725651_223725976
0.00118
0.081
DataSet_01_470
View details
AFG3L2
12353003_12353157_12356692_12356830_12351304_12351412
0.00000
0.46
DataSet_01_470
View details
AFMID
76187050_76187141_76198575_76198684_76183397_76183514
0.00001
-0.136
DataSet_01_470
View details
AHSG
186336285_186336426_186337645_186337729_186334975_186335139
0.00000
0.025
DataSet_01_470
View details
AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00000
-0.197
DataSet_01_470
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00000
-0.185
DataSet_01_470
View details
AHSG
186336300_186336426_186337645_186337729_186334975_186335139
0.00000
0.017
DataSet_01_470
View details
AHSG
186336324_186336426_186337645_186337729_186334231_186334316
0.00607
0.008
DataSet_01_470
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Showing 1 to 10 of 126 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACP1
271892_272065_271892_271939_272191_272305
0.00016
-0.111
DataSet_01_470
View details
AFMID
76201683_76201834_76201683_76201819_76202026_76202131
0.00703
0.272
DataSet_01_470
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ALB
74275095_74275183_74275095_74275140_74276028_74276126
0.00000
-0.948
DataSet_01_470
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APEX1
20923736_20923932_20923736_20923862_20924072_20924260
0.00097
0.039
DataSet_01_470
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ATP6V0B
44441471_44441646_44441471_44441520_44441761_44441845
0.00147
0.118
DataSet_01_470
View details
BAG6
31620176_31620477_31620200_31620477_31619432_31619553
0.00478
-0.131
DataSet_01_470
View details
C8orf59
86131464_86131592_86131551_86131592_86129614_86129731
0.00596
-0.242
DataSet_01_470
View details
CFB
31912561_31912806_31912561_31912630_31912954_31912963
0.00011
-0.093
DataSet_01_470
View details
CNBP
128890476_128890614_128890497_128890614_128890288_128890381
0.00024
-0.147
DataSet_01_470
View details
CPNE1
34220084_34220307_34220232_34220307_34219866_34219947
0.00018
-0.192
DataSet_01_470
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Showing 1 to 10 of 53 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSL3
223782763_223782873_223782787_223782873_223781036_223781214
0.00322
-0.052
DataSet_01_470
View details
AHSG
186338374_186339089_186338883_186339089_186336300_186336426
0.00265
0.025
DataSet_01_470
View details
AP1G2
24031170_24031275_24031170_24031262_24031496_24031624
0.00650
-0.079
DataSet_01_470
View details
AP1G2
24031170_24031316_24031170_24031275_24031496_24031624
0.00732
0.155
DataSet_01_470
View details
APOA2
161193139_161193247_161193139_161193215_161193384_161193418
0.00006
0.228
DataSet_01_470
View details
APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00149
-0.011
DataSet_01_470
View details
APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00242
-0.009
DataSet_01_470
View details
ATP6V1G2-DDX39B
31508190_31508343_31508190_31508311_31509726_31509925
0.00208
0.133
DataSet_01_470
View details
B4GALT3
161146223_161146896_161146223_161146369_161147212_161147269
0.00058
0.101
DataSet_01_470
View details
CFB
31912756_31912963_31912954_31912963_31912561_31912630
0.00015
-0.115
DataSet_01_470
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00000
0.056
DataSet_01_470
View details
ACADVL
7124084_7124377_7124084_7124149_7124242_7124377
0.00043
0.11
DataSet_01_470
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ACADVL
7123440_7123995_7123440_7123516_7123922_7123995
0.00474
-0.069
DataSet_01_470
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00289
0.011
DataSet_01_470
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ACTG1
79477952_79478652_79477952_79478134_79478213_79478652
0.00398
0.008
DataSet_01_470
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AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00145
-0.176
DataSet_01_470
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AP1G2
24034814_24035369_24034814_24034910_24035272_24035369
0.00235
-0.143
DataSet_01_470
View details
AP1G2
24032792_24033065_24032792_24032818_24032924_24033065
0.00897
-0.098
DataSet_01_470
View details
APEX1
20923736_20924260_20923736_20923862_20924072_20924260
0.00000
0.083
DataSet_01_470
View details
ARAP1
72407593_72408240_72407593_72407699_72408027_72408240
0.00976
-0.03
DataSet_01_470
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
1595603
C
G
0.00017
CDK11B,SLC35E2B
-
FALSE
AluJr
SINE,Alu
chr1
36067760
T
C
0.00044
PSMB2
-
TRUE
AluSz
SINE,Alu
chr1
171509327
G
A
0.00110
PRRC2C
+
FALSE
chr1
145291108
A
C
0.00827
NBPF20
+
FALSE
chr1
10519936
T
C
0.00607
.
FALSE
AluJr
SINE,Alu
chr1
79109337
G
T
0.00790
IFI44L
+
FALSE
LTR26
SINE,Alu
chr1
142804438
G
T
0.00618
.
FALSE
chr1
25570561
T
A
0.00425
RSRP1
-
FALSE
Alu
SINE,Alu
chr1
16932144
A
C
0.00559
NBPF1
-
FALSE
chr1
1344757
A
G
0.00024
.
FALSE
AluSx1
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression