Dataset Overview
RBPXRCC5
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR715XZS
PlatformHiSeq
Pubmed ID32252787

XRCC5 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of XRCC5
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of XRCC5


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2102484205TA0.00434MAP4K4+FALSE
chr19160982TC0.00304.FALSEAluJbSINE,Alu
chr128835937AG0.00121SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr140307166GA0.00026TRIT1-FALSE
chr1145292925CT0.00817NBPF20+FALSE
chr344791554TC7.29341E-07KIAA1143-FALSEAluJrSINE,Alu
chr4153898316AG0.00312FHDC1+TRUEAluJoSINE,Alu
chr136770605CT8.58098E-05THRAP3+FALSE(T)nSINE,Alu
chrX77083007TC0.00371MAGT1-TRUEAluSgSINE,Alu
chr189477559CT0.00044GBP3-FALSE
chr11595006TC0.00156CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr177166017GA0.00146.FALSE
chr717384393AG1.74996E-06AHR+TRUEAluSxSINE,Alu
chr125168124GC0.00669CLIC4+FALSE
chr1179310439CT0.00907SOAT1+FALSE
chr399516879AT7.79377E-13MIR548G-FALSE
chr738764459TC0.00789VPS41-TRUEAluSpSINE,Alu
chr12125511226AG0.00205THRIL-FALSEAluSx1SINE,Alu
chr1175129946CT0.00466KIAA0040-FALSE(TCT)nSINE,Alu
chr194343023AG0.00363DNTTIP2-FALSE
chr399463810GT0.00599MIR548G,COL8A1+,-FALSE
chr140923019GA0.00019ZFP69B+FALSE
chr2191799595AG0.00162GLS+FALSE
chr119543282TC0.00020LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr541917720TG0.00727C5orf51+FALSE
chr1120286837AG0.00153PHGDH+FALSE
chr4165998019TC0.00849TMEM192-TRUEAluSxSINE,Alu
chr1118170485TC0.00281FAM46C+FALSE(TG)nSINE,Alu
chr2242512138AG7.67847E-06BOK+FALSE
chr110519888TC0.00218.FALSEAluJrSINE,Alu
chr349396588TC0.00533RHOA-FALSE
chr299772827AG0.00377LIPT1+TRUEAluSx1SINE,Alu
chr7129472357AG0.00287UBE2H-FALSE
chr6111348022AT2.41155E-06RPF2+FALSE
chr42940265TC0.00413NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr413606576AT0.00737BOD1L1-FALSE
chr156961756AG0.00265PLPP3-FALSE
chr733060946AG0.00542NT5C3A-FALSE
chr417804872TC0.00096DCAF16-TRUEAluSxSINE,Alu
chr438946824CT0.00250FAM114A1+FALSE
chr388104159AC0.00279CGGBP1-FALSE
chr6160211652CG0.00719MRPL18+FALSE
chr128832533GA0.00761SNHG3,RCC1+FALSE
chr16283305TC0.00554ICMT-TRUEAluSx3SINE,Alu
chr314239845GA0.00375LSM3+FALSE
chr1194801633AT0.00808SRSF8+FALSE
chr3156259295TC0.00039SSR3-TRUEAluSq2SINE,Alu
chr2206988075GA0.00672NDUFS1-FALSE
chr2120980896TG0.00132TMEM185B-FALSE
chr2206986978TC0.00159.FALSEAluJrSINE,Alu
chr1179044110AG0.00885FAM20B+TRUEAluSxSINE,Alu
chr642857111AG0.00021RPL7L1+FALSEAluSpSINE,Alu
chr2218571345AG0.00113PEX26+TRUEAluSzSINE,Alu
chr5177576458AT0.00427.FALSE
chr12125512507AG0.00276.FALSEAluYSINE,Alu
chr3185826764CT0.00364ETV5-FALSE
chr1680636805TG0.00766CDYL2-FALSE
chr2239069181TC0.00346CBY1+FALSE
chr1144822920AT0.00040NBPF20,NBPF9+FALSE
chr4113197769TC0.00101TIFA-FALSE
chr1155217438AT0.00610FAM189B-FALSE
chr1167765170GT0.00185UNC93B1-FALSE
chr5114951140TG0.00761TMED7-TICAM2,LOC101927100,TMED7+,-FALSE
chr1146495574CT0.00085LOC728989-FALSE
chr2128602462TC0.00298.FALSEAluSq2SINE,Alu
chr5125961509AG0.00141PHAX+TRUEAluSz6SINE,Alu
chr16314822TC0.00300GPR153-FALSE
chr344791351TC0.00497KIAA1143-TRUEAluJrSINE,Alu
chr146164678TC0.00773IPP-TRUEAluJbSINE,Alu
chr115909744CT0.00225AGMAT-FALSE
chr4120979770TC0.00437.FALSEAluSgSINE,Alu
chr1688789703CG0.00498PIEZO1-FALSE
chr6134492481AC0.00340SGK1-FALSE
chr1352952575GA0.00030THSD1-FALSE
chr128661656AG0.00012MED18+TRUEAluSgSINE,Alu
chr352084404AT0.00032DUSP7-FALSE(A)nSINE,Alu
chr5110463621GT0.00786WDR36+FALSE(T)nSINE,Alu
chr3140695493CA0.00559SLC25A36+FALSE
chr1153617973AG4.00129E-07CHTOP+FALSE
chr1168218504TC0.00748.FALSEAluSzSINE,Alu
chr11419743AG0.00848ATAD3B+TRUEAluYk2SINE,Alu
chr227315252GA0.00377KHK+FALSE
chr7115898258AT0.00314TES+FALSE(T)nSINE,Alu
chr1420923558AC0.00373APEX1+FALSE
chr128836975AG0.00782SNHG3,RCC1+TRUEAluScSINE,Alu
chr333187831CT6.36740E-05CRTAP+FALSE
chr1749042325TC0.00798SPAG9-TRUEAluJbSINE,Alu
chr122929376AG0.00378EPHA8+FALSE
chr23597974TC1.93309E-05RNASEH1-FALSE
chr345721934AG0.00639LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr122855441CT0.00884ZBTB40+FALSE
chr5139680027AG0.00155PFDN1-FALSE
chr110520692TC0.00973DFFA-TRUEAluSc8SINE,Alu
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr152375564TC0.00866RAB3B-FALSE
chr128661767AG0.00144MED18+TRUEAluSgSINE,Alu
chr1153909069GC5.11201E-05DENND4B-FALSE
chr3156258230TC0.00176SSR3-TRUEAluYk3SINE,Alu
chr39934605TC3.00360E-07JAGN1+FALSE
chr3112720117GT0.00125GTPBP8+FALSE
chr19989022AG0.00038LZIC-FALSEL1MB5SINE,Alu
chr315114293TC2.60553E-05RBSN-TRUEAluYSINE,Alu
chr111084103TA0.00968TARDBP+FALSE
chr1149816373GA0.00364.FALSE(A)nSINE,Alu
chr12990912AC0.00244WNK1+FALSE
chr189447715TG0.00137KYAT3,RBMXL1-FALSE
chr124861704GA0.00345RCAN3+FALSE
chr29630248GT0.00764ADAM17-FALSE
chr3158320703CA0.00841MLF1+FALSE
chr1169811639GC0.00134C1orf112+FALSE
chr285776644TC0.00127GGCX-TRUEAluSz6SINE,Alu
chr1227955296CT3.87648E-07KLHL42+FALSE
chr237329214TC0.00081.FALSEAluJr4SINE,Alu
chr128826118AG0.00175PHACTR4+TRUEAluJbSINE,Alu
chr2191067763AT0.00038C2orf88+FALSE
chr1741133090AT0.00148RUNDC1+FALSE
chr10865825CT0.00088LARP4B-FALSE
chr110042937AG2.41028E-05NMNAT1+TRUEAluScSINE,Alu
chr43219613AC0.00361HTT+FALSE
chr439551975TC5.31269E-07UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr117313654CT0.00714ATP13A2-FALSE
chr76064010CA0.00304EIF2AK1-FALSE
chr837613106TC0.00626ERLIN2+FALSE
chr143272841AT0.00029SVBP-FALSE
chr19163328TC0.00287.FALSEAluSpSINE,Alu
chr1142660072TG0.00773.FALSE
chr919376252AT0.00367.FALSE
chr1113672569AG0.00742.FALSEAluJbSINE,Alu
chr116958064AG0.00446.FALSE
chr110518797TC0.00148.FALSEAluSx1SINE,Alu
chr115993713AT7.45571E-05.FALSEAluSx4SINE,Alu
chr1942376711AG0.00223.FALSEAluSpSINE,Alu
chr719736460AG6.53378E-05TWISTNB-FALSEMER33SINE,Alu
chr116133978TC0.00625UQCRHL-FALSE
chr275883878TC0.00838MRPL19+FALSEHAL1SINE,Alu
chr255459824CT0.00763RPS27A+FALSE
chr199672346TC0.00222.FALSEAluJrSINE,Alu
chr127426756AG0.00384SLC9A1-FALSE
chr286249906TC0.00352LOC90784-TRUEAluJrSINE,Alu
chr146125880TC0.00686GPBP1L1-FALSE
chr237331560TC6.28398E-05.FALSEAluJbSINE,Alu
chr1155144757TC0.00758KRTCAP2-FALSETigger19bSINE,Alu
chr368685888GA0.00280.FALSE
chr16583036TC0.00296NOL9-TRUEAluSx4SINE,Alu
chr2176042866AT0.00596ATP5G3-FALSE
chr1118502732CT0.00151WDR3,SPAG17+,-FALSE
chr1167782827GA0.00163ALDH3B1+FALSE
chr193307479CA0.00085FAM69A,RPL5+,-FALSE
chr1757281069AG0.00278PRR11+TRUEAluSzSINE,Alu
chr111083395CT0.00616TARDBP+FALSE
chr1145283980CT0.00113NBPF20,NOTCH2NL+FALSE
chr151822219GA0.00018EPS15-FALSE
chr537290571TC0.00097.FALSEAluSzSINE,Alu
chr314986399TC1.19850E-05FGD5-AS1-TRUEAluSq2SINE,Alu
chr4159176109CA0.00042TMEM144+FALSEMIRSINE,Alu
chr110517567TC0.00262.FALSEAluSx1SINE,Alu
chr1114940210TG0.00028TRIM33-FALSE(T)nSINE,Alu
chr11653093AG0.00674CDK11B,CDK11A-FALSEL2SINE,Alu
chr1022825288GA0.00051PIP4K2A-FALSE
chr12124146569AG0.00013GTF2H3+TRUEAluSq2SINE,Alu
chr5149781426AG0.00977CD74-FALSE
chr125570566CG0.00326RSRP1-FALSEAluSINE,Alu
chr1780280865GA0.00984SECTM1-FALSE
chr128661653AG9.75782E-05MED18+TRUEAluSgSINE,Alu
chr595223443CT0.00255ELL2-FALSE
chr1160967855TC0.00042F11R-TRUEAluSpSINE,Alu
chr3195701389CA0.00227SDHAP1-FALSE
chr3182661952CT0.00438DCUN1D1-FALSEA-richSINE,Alu
chr11234671GA0.00100ACAP3-FALSE
chr1109818160TG3.82986E-06CELSR2+FALSE
chr7128294489GT0.00354LINC01000+FALSE
chr1246831356GA0.00616CNST+FALSE
chr1610624997TC1.19407E-05EMP2-TRUEAluSx3SINE,Alu
chr3124774432TG0.00754HEG1-FALSE
chr153291425AG2.55913E-05ZYG11B+TRUEAluJrSINE,Alu
chr7100804430CT0.00629AP1S1+FALSE
chr125894462AG0.00101LDLRAP1+FALSEMIRbSINE,Alu
chr127203728AT0.00528.FALSE
chr1132125961CT0.00118RCN1+FALSE
chr132661578CT0.00694TXLNA+FALSE(T)nSINE,Alu
chr2202030311TA0.00732CFLAR+FALSESVA_ASINE,Alu
chr9115448785CT0.00195INIP-FALSEAluSzSINE,Alu
chr15102512797AG0.00080WASH3P+FALSE
chr1114306374GA5.13313E-06RSBN1-FALSE
chr1113247898GA0.00077RHOC-FALSE
chr466439443TC0.00593EPHA5-FALSE
chr4109542624GA0.00048RPL34+FALSEMIRbSINE,Alu
chr1110276861TC0.00180GSTM3-FALSELTR77SINE,Alu
chr72274209TC0.00578MRM2-FALSEAluJrSINE,Alu
chr165694080CT0.00442AK4+FALSE(TCCC)nSINE,Alu
chr51317949CT0.00173CLPTM1L-FALSE
chr146827871GA0.00860NSUN4+FALSE
chr124286327GA0.00053PNRC2+FALSE
chr2035521047TA0.00064TLDC2,SAMHD1+,-FALSE
chr2204162277AG0.00097CYP20A1+TRUEAluSxSINE,Alu
chr120978332AT0.00765PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr1272096335AG1.07858E-05TMEM19+FALSEAluSz6SINE,Alu
chr1081114959CT0.00048PPIF+FALSEMSTASINE,Alu
chr186986227GA3.73397E-05LAMA1-FALSE
chr642856156AG0.00190RPL7L1+TRUEAluSzSINE,Alu
chr1681745173CA0.00179CMIP+FALSE
chr1179042550AG0.00831FAM20B+TRUEAluSx1SINE,Alu
chr330733690CA0.00353TGFBR2+FALSE
chr2277003AG1.77913E-11ACP1+FALSE
chr1148004475CG7.81276E-06NBPF8-FALSE
chr4164245873TA0.00014NPY1R-FALSE
chr1210761846AG0.00224MAGOHB-FALSE
chr115755550AC0.00969EFHD2+FALSE
chr115394286CG0.00260KAZN+FALSE
chr17421931TC0.00260VPS53-TRUEAluSxSINE,Alu
chr167874731TC0.00145SERBP1-TRUEAluSx3SINE,Alu
chr13110407579TG0.00751IRS2-FALSE(T)nSINE,Alu
chr3156259229TC1.62025E-06SSR3-TRUEAluSq2SINE,Alu
chr1292537721AT0.00057BTG1-FALSE
chr133145978AT0.00288SYNC,RBBP4+,-FALSE
chr1220154768CT0.00067RNU5F-1,EPRS+,-FALSE
chr126608019TA3.63623E-05.FALSE
chr145279900TC0.00073.FALSE(TCTT)nSINE,Alu
chr1217804325GA0.00229GPATCH2-FALSE
chr11421531CA0.00467ATAD3B+FALSE
chr642855972AG0.00182RPL7L1+TRUEAluSzSINE,Alu
chr1567557AG0.00649.FALSE
chr1119427687GC0.00823TBX15-FALSE
chr119578192GA0.00246MRTO4+FALSE
chr372426059TA0.00417RYBP-FALSE
chr1169293721GA0.00978NME7-FALSE
chr1220231330TC0.00427RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr167874731TC0.00565SERBP1-TRUEAluSx3SINE,Alu
chr1155853251AG0.00207SYT11+TRUEAluJbSINE,Alu
chr552389815AG0.00486ITGA2+TRUE
chr1583826212CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr110517352TC1.76732E-06.FALSEAluJrSINE,Alu
chr2025428646AG9.98122E-05GINS1+TRUEAluJbSINE,Alu
chr1674698531TC0.00702RFWD3-TRUEAluSx3SINE,Alu
chr7115898442GC2.36867E-05TES+FALSEAluSxSINE,Alu
chr145452227GC0.00256EIF2B3-FALSE
chr1204521160AG0.00231MDM4+TRUEAluSpSINE,Alu
chr16282587TC0.00487ICMT-TRUE
chr127338911CT0.00455FAM46B-FALSE
chr116893686GC0.00171NBPF1-FALSE
chr116889466AC0.00665NBPF1-FALSEL1MC4SINE,Alu
chr5130536847AG0.00917LYRM7+TRUEAluSx4SINE,Alu
chr211053740CT0.00402KCNF1+FALSE
chr2203741640TC0.00419.FALSEAluJrSINE,Alu
chr1254634306TC0.00616CBX5-TRUEAluJrSINE,Alu
chr126299050GA0.00110PAFAH2-FALSE
chr42940347TC0.00113NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1098281496TC0.00509TM9SF3-FALSE
chr19328102AG7.16435E-05H6PD+TRUEAluJrSINE,Alu
chr269688901TC0.00503AAK1-TRUEAluSq2SINE,Alu
chr128825337AG0.00904PHACTR4+TRUEAluSgSINE,Alu
chr5134236287AG0.00538TXNDC15+TRUEAluSqSINE,Alu
chr133148210AG0.00342SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr323959425CG0.00000RPL15+FALSE
chr287002706GA0.00178RMND5A+FALSE
chr1156567496CT0.00012GPATCH4-FALSEMIR3SINE,Alu
chr116893822CT0.00808NBPF1-FALSE
chr16311399AG0.00126GPR153-FALSE
chr111979809AC0.00525KIAA2013-FALSE
chr11597403CT0.00033CDK11B,SLC35E2B-FALSE
chr2130807905GT0.00634FAR2P1-FALSE
chr255516908AG0.00016CCDC88A-FALSE(GA)nSINE,Alu
chr12125511958AG0.00494THRIL-FALSEAluSx1SINE,Alu
chr115989141CG0.00091.FALSE
chr1148556726GT0.00976.FALSE
chr2136542427TA0.00075UBXN4+FALSEL1ME4bSINE,Alu
chr1619513719TA0.00730GDE1-FALSEAluJrSINE,Alu
chr125889571GA0.00344LDLRAP1+FALSE
chr136067925TC3.39837E-06PSMB2-TRUEAluSzSINE,Alu
chr161922437GT0.00359NFIA+FALSE
chr226613948AG0.00218EPT1+FALSE
chr120826781CT0.00296MUL1-FALSE
chr345960578GA0.00632FYCO1-FALSE
chr136067817TC0.00938PSMB2-TRUEAluSzSINE,Alu
chr140705200GA3.20116E-08RLF+FALSE
chr237330172TG0.00972.FALSE
chr1765335292TC6.31480E-06PSMD12-TRUEAluSxSINE,Alu
chr14105270483GT7.92193E-06ZBTB42+FALSE
chr1204374665GA0.00717PPP1R15B-FALSE
chr324019977AC0.00281NR1D2+FALSE
chr116932429CG0.00823NBPF1-FALSEL1MC2SINE,Alu
chr76370194CT0.00029FAM220A-FALSE
chr29630231CT0.00895ADAM17-FALSE
chr1241796949GA0.00053OPN3,CHML-FALSE
chr1463841401GC0.00014PPP2R5E-FALSE
chr1269237534AG0.00106MDM2+TRUE
chr716640491GA0.00478ANKMY2-FALSE
chr76066461TC2.08606E-05EIF2AK1-FALSE
chr127181647GA0.00103ZDHHC18+FALSE
chr17828190AC0.00049CAMTA1+FALSE(A)nSINE,Alu
chr398518157AT8.60022E-05DCBLD2-FALSE
chr1117530188AG0.00199PTGFRN+FALSE
chr146164493TC0.00977IPP-TRUEAluJbSINE,Alu
chr116933110TC0.00821NBPF1-FALSEL1MC2SINE,Alu
chr1765334867TC1.03096E-06PSMD12-TRUEAluSqSINE,Alu
chr1138266CT7.30419E-05LOC729737-FALSE
chr1156233189CT5.51743E-05SMG5-FALSE
chr136316571AC0.00893AGO4+FALSE
chr5149363414AG0.00503SLC26A2+TRUEAluJrSINE,Alu
chr110517653TC0.00792.FALSEAluSx1SINE,Alu
chr2206983491TC0.00505.FALSEAluSxSINE,Alu
chr1269237020AG0.00150MDM2+TRUE
chr111810674GA0.00279AGTRAP+FALSE
chr115818065TC0.00372CASP9-TRUEAluJbSINE,Alu
chr2180810264AT1.24157E-05CWC22-FALSE
chr187328433TC3.09926E-06SEP15-FALSE
chr19416151GA0.00292SPSB1+FALSE
chr12125511311AG0.00299THRIL-FALSEAluSx1SINE,Alu
chr3185646406AT0.00023TRA2B-FALSE
chr4113152490GA0.00221.FALSE
chrX119572534CA0.00387LAMP2-FALSE
chr110041422AG0.00115NMNAT1+TRUEAluYj4SINE,Alu
chr830536544TC0.00122GSR-TRUEAluSpSINE,Alu
chr192862836AG0.00430.FALSEAluJrSINE,Alu
chr126755643AG0.00955LIN28A+FALSEAluScSINE,Alu
chr1226333560AT0.00339ACBD3-FALSE(CAAAA)nSINE,Alu
chr2217366515AG0.00357.FALSEAluSzSINE,Alu
chr2121749583TC0.00120GLI2+FALSE
chr315114398TC0.00758RBSN-TRUEAluYSINE,Alu
chr119543353TC0.00081LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1109475543AG0.00495GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr1681064560AG0.00014CENPN+TRUEAluSgSINE,Alu
chr398299365TG0.00133CPOX-FALSE
chr3176739159AC0.00304TBL1XR1-FALSE
chr3113370193CT4.09251E-05USF3-FALSEUCON34SINE,Alu
chr2230876757GC0.00321FBXO36+FALSE
chr2113334241AG0.00388POLR1B+TRUE
chr116893691CA0.00371NBPF1-FALSE
chr119244904GA0.00487IFFO2-FALSE
chr1115259768TC0.00156CSDE1-FALSE
chr113942885CA0.00038PDPN+FALSE
chr633384325GT0.00456.FALSE
chr1183218868TG0.00091NMNAT2-FALSE
chr1116238478CT0.00834VANGL1+FALSE
chr185733095GA0.00651BCL10-FALSE

Differential Expression Gene Analysis