Dataset Overview
RBPAKAP8L
Knock-MethodshRNA
RBP FamilyAKAP95
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR809ISU
PlatformHiSeq
Pubmed ID32252787

AKAP8L - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of AKAP8L
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of AKAP8L


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr231423365GT4.32087E-05CAPN14-FALSE
chr121810575TC0.00827NBPF3+FALSE
chr3183890868AG5.00274E-08DVL3+FALSEL2SINE,Alu
chr186117122TC0.00462ZNHIT6-FALSEAluSgSINE,Alu
chr271298486TC0.00408NAGK+FALSE
chr261277798AG0.00077PEX13+TRUEAluYSINE,Alu
chr133139178AG0.00108RBBP4+TRUEAluSx3SINE,Alu
chr285546474TC0.00051TGOLN2-TRUEAluScSINE,Alu
chr11337738CA4.14710E-05MRPL20-FALSE
chr315780233CT1.83528E-06ANKRD28-FALSEMER11BSINE,Alu
chr986584220GA0.00318HNRNPK-FALSE
chr928607TC0.00146WASH1-FALSE
chr1109856391GC0.00569SORT1-FALSE
chr730634661CG3.93145E-07GARS+FALSE
chr373116347TA0.00109PPP4R2+FALSE
chr128835847AG0.00042SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr128825337AG0.00904PHACTR4+TRUEAluSgSINE,Alu
chr286252025TC3.86923E-05POLR1A-TRUEAluSq2SINE,Alu
chr136068295TC2.11660E-05PSMB2-TRUEAluScSINE,Alu
chr1431916927TC1.57126E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr1120611964GC0.00077NOTCH2-FALSE
chr2208619742AG0.00500CCNYL1+TRUEAluJbSINE,Alu
chr254858511CT0.00124SPTBN1+FALSE
chr1100548868TC8.06321E-05MFSD14A+FALSE
chr167874270GA0.00019SERBP1-FALSE
chr3195411267AG1.93837E-05SDHAP2+FALSE
chr2227662565AC0.00028IRS1-FALSE
chr224225460AG0.00081.FALSEAluSq2SINE,Alu
chr299812414AG9.82924E-05MRPL30+TRUEAluSxSINE,Alu
chr1145512944AG0.00171NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr123636030AT0.00067HNRNPR-FALSE
chr286252222TC0.00468POLR1A-TRUEAluSq2SINE,Alu
chr348787684TC0.00813PRKAR2A-TRUEAluSpSINE,Alu
chr348787052TC0.00226PRKAR2A-TRUEAluSx3SINE,Alu
chr110518831TC0.00410.FALSEAluSx1SINE,Alu
chr1946052975TC0.00652OPA3-TRUEAluSz6SINE,Alu
chr115993699CA0.00011.FALSEAluSx4SINE,Alu
chr237329307TC0.00137.FALSEAluJr4SINE,Alu
chr534906587TC0.00442RAD1-TRUEAluJoSINE,Alu
chr1552840681CT0.00789ARPP19-FALSEAluSx1SINE,Alu
chr1120839682AG0.00073FAM72B+FALSE
chr211321778GT0.00402ROCK2-FALSEAluSx1SINE,Alu
chr537291446TC6.87884E-05.FALSEAluSx3SINE,Alu
chr110517306TC0.00176.FALSEAluJrSINE,Alu
chr120945264AC0.00605CDA+FALSE
chr7100860467CG0.00267PLOD3-FALSE
chr3101399945AG0.00965RPL24-FALSE
chr286252136TC0.00015POLR1A-TRUEAluSq2SINE,Alu
chr174721376AG0.00177PLD2+FALSE
chr3197611048AG0.00064.FALSEAluSx1SINE,Alu
chr19788153GA0.00198PIK3CD+FALSEAluSxSINE,Alu
chr144818525TC0.00442ERI3-FALSE
chr110042987AG0.00149NMNAT1+TRUEAluScSINE,Alu
chr2128950497AG4.96654E-06UGGT1+TRUEAluScSINE,Alu
chr6166824706AT0.00048RPS6KA2-FALSE(T)nSINE,Alu
chr121904374AC0.00198ALPL+FALSE
chr163207362AT1.09222E-05.FALSE
chr1681064649AG0.00019CENPN+TRUEAluSgSINE,Alu
chr131426815AG0.00797PUM1-FALSE
chr35259480TA5.79324E-05EDEM1+FALSE
chr2202028727AG0.00833CFLAR+TRUEAluSx1SINE,Alu
chr1155851645AG4.46102E-05SYT11+TRUEAluSq2SINE,Alu
chr9128729385CA0.00170PBX3+FALSE
chr1118408218CA0.00857GDAP2-FALSE
chr116932144AC1.90883E-05NBPF1-FALSE
chr1913884096AG0.00049MRI1+TRUEAluSzSINE,Alu
chr199164434GA0.00309SNX7+FALSE
chr1670695982TC0.00926MTSS1L-FALSE
chr644222157GA0.00856SLC35B2-FALSE
chr1298943214AG4.64520E-05TMPO+TRUEAluSzSINE,Alu
chr124175288CG0.00646FUCA1-FALSE
chr126601329CT3.97278E-05MRPL51-FALSE
chr1145689568AG8.25649E-05NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr1450713578TC0.00260L2HGDH-TRUEAluSxSINE,Alu
chr1269237558AG0.00034MDM2+TRUE
chr1114443618AG0.00910AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr1169101274TG0.00026ATP1B1+FALSE(T)nSINE,Alu
chr1015120275TC0.00017ACBD7-TRUEL1PA7SINE,Alu
chr129098987TA0.00180M6PR-FALSE
chr638670804GC0.00400GLO1-FALSE
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr1169768080CA0.00857C1orf112+FALSE
chr162628531AG0.00716PATJ+TRUEAluSg4SINE,Alu
chr1145284134GC0.00203NBPF20,NOTCH2NL+FALSE(TG)nSINE,Alu
chr119543282TC0.00228LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr298409998GT0.00261TMEM131-FALSE
chr439552646TC0.00555UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1569782TC0.00010.FALSE
chr133149496AG0.00308SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1144930940TC0.00181NBPF20,PDE4DIP+,-FALSE
chr439550549TC0.00014UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1220231959TC0.00464RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr185742157GC0.00514BCL10,LOC646626+,-FALSE
chr144818549CT0.00108ERI3-FALSE
chr791630349TA0.00111AKAP9+FALSE
chr42943361TC7.19955E-07NOP14-AS1,NOP14+,-FALSE
chr116889820CT0.00012NBPF1-FALSE
chr5102345546AC0.00463PAM+FALSE
chr247562597AG0.00016LOC101927043-FALSEBC200SINE,Alu
chr147074462AG0.00011MOB3C-FALSE
chr286249930TC0.00054LOC90784-TRUEAluJrSINE,Alu
chr1109737090GA0.00173KIAA1324+FALSE
chr9131872860CT0.00141CRAT-FALSE
chr1145689566AG0.00918NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr12125511958AG0.00494THRIL-FALSEAluSx1SINE,Alu
chr128835934AG3.31538E-06SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr19163402TC0.00014.FALSEAluSpSINE,Alu
chr5180682612AT0.00235CTC-338M12.4+FALSE
chr264479079GA0.00452LOC100507006+FALSE
chr116958064AG2.44983E-05.FALSE
chr1144821888CG0.00093NBPF20,NBPF9+FALSE
chr417803604TC0.00172DCAF16-TRUEAluYSINE,Alu
chr1060047608AG0.00356CISD1+FALSE(A)nSINE,Alu
chr272968436GC0.00171EXOC6B-FALSE
chr1144874760TC0.00267NBPF20,PDE4DIP+,-FALSE
chr2234386134AG0.00196USP40-FALSE
chr147716046AT0.00696STIL-FALSE
chr110517456TC0.00722.FALSEAluSx1SINE,Alu
chr255516941CT0.00110CCDC88A-FALSE
chr128834154GT0.00012SNHG3,RCC1+FALSEAluSgSINE,Alu
chr1220231263TC0.00300RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr145976112AG1.14998E-06MMACHC+TRUEAluJrSINE,Alu
chr3183900680GC0.00294AP2M1+FALSEMIR3SINE,Alu
chr12133298349AG0.00000PGAM5+TRUEAluSpSINE,Alu
chr1120612168CT0.00607NOTCH2-FALSE
chr12133298937AG0.00240PGAM5+TRUEAluSgSINE,Alu
chr1145284132GA0.00338NBPF20,NOTCH2NL+FALSE(TG)nSINE,Alu
chr133148623AG4.79591E-07SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr128826128AG0.00483PHACTR4+TRUEAluJbSINE,Alu
chr2239259540GA0.00493CBX6-FALSE
chr632800221CT0.00900.FALSE(GCATCA)nSINE,Alu
chr1590819655AG0.00174.FALSEAluSxSINE,Alu
chr111783889AG0.00746.FALSEAluSqSINE,Alu
chr353319203CG0.00453DCP1A-FALSE
chr1153920564AG0.00323CRTC2-FALSE
chr1203277243GT1.60795E-05BTG2+FALSE
chr2206987229TC0.00743.FALSEAluSxSINE,Alu
chr135899684CT0.00051KIAA0319L-FALSEAluSc8SINE,Alu
chr9125887702CT0.00019STRBP-FALSE
chr842876058AG0.00029HOOK3+TRUEAluSq2SINE,Alu
chr6126661502GT0.00873CENPW+FALSE
chr1145281408CT0.00220NBPF20,NOTCH2NL+FALSE
chr1146033815GA0.00307NBPF20,NBPF10,NBPF25P,NBPF11+,-FALSE
chr1156206121GA0.00423PMF1-BGLAP,PMF1+FALSE
chr119234174AG0.00046IFFO2-FALSE
chr8144357992AG0.00780GLI4+FALSE
chr286252214TC0.00930POLR1A-TRUEAluSq2SINE,Alu
chr1015119789TC0.00366ACBD7-TRUEAluSx1SINE,Alu
chr344790772TC0.00024KIAA1143-TRUEAluYSINE,Alu
chr1109818161CT0.00382CELSR2+FALSE
chr426433556AC3.10862E-15RBPJ+FALSE
chr2103333653TC0.00426MFSD9-FALSEAluYm1SINE,Alu
chr138423055CA0.00015SF3A3-FALSE
chr310192694AG0.00277VHL+TRUEAluSx1SINE,Alu
chr729963082GA0.00118SCRN1-FALSE
chr2120439459CA0.00273TMEM177+FALSE
chr111347164AC0.00667UBIAD1+FALSE
chr12120898697AG0.00488GATC+TRUEAluYSINE,Alu
chr577655392TC0.00080SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr117393889AG0.00390PADI2-FALSE
chr5112350098CT7.36383E-05DCP2+FALSE
chr796318078AT0.00790.FALSE
chr132953214AG0.00837ZBTB8B+TRUEAluSzSINE,Alu
chr178342729AG0.00175MIGA1+TRUEFRAMSINE,Alu
chr2147676711GA0.00316MCM3AP-FALSE
chr1115592820TC0.00107TSPAN2-FALSE
chr1144868170CT0.00750NBPF20,PDE4DIP+,-FALSE
chr1207942472AG0.00273CD46+TRUEAluSg4SINE,Alu
chr140306898TC0.00384TRIT1-FALSE
chr133149486AG0.00874SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr116933749AG0.00764NBPF1-FALSEGA-richSINE,Alu
chr1145693061AG0.00158NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr1201846630CA0.00041IPO9+FALSE(CA)nSINE,Alu
chr439550085TC3.55103E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr133146255CA0.00182SYNC,RBBP4+,-FALSE
chr1206581246TC0.00210SRGAP2+FALSE
chr1186321189AG0.00010TPR-FALSE
chr237331065TC0.00017.FALSEAluSx1SINE,Alu
chr1734942575GA0.00374GGNBP2+FALSEA-richSINE,Alu
chr2161130521GA0.00454RBMS1-FALSE
chr186816600AG0.00830ODF2L-FALSEL1PA7SINE,Alu
chr133322929TG0.00340S100PBP+FALSEAluSpSINE,Alu
chr19328120AG1.75282E-05H6PD+TRUEAluJrSINE,Alu
chr132687473TG0.00892TMEM234,EIF3I+,-FALSE
chr11252723TC7.44553E-05CPSF3L-TRUEAluSpSINE,Alu
chr310193797AG0.00261VHL+TRUEAluSxSINE,Alu
chr1206516261CT0.00179SRGAP2+FALSE
chr145504720GC0.00759ZSWIM5-FALSE
chr11622754AG0.00221CDK11B,SLC35E2B-FALSEMLT1F2SINE,Alu
chr145975628AG0.00413MMACHC+TRUEAluSx4SINE,Alu
chr145976259AC0.00015MMACHC+FALSE
chr2206987635TC0.00930.FALSEAluJbSINE,Alu
chr1145441841AT0.00636NBPF20,NBPF10,TXNIP+FALSE
chr42516790GT7.50309E-05RNF4+FALSE
chr1153914500GA3.11507E-05DENND4B-FALSE
chr7152343700TC0.00061XRCC2-TRUEAluSx3SINE,Alu
chr146075720AG0.00105NASP+TRUEAluSx4SINE,Alu
chr417803616TC1.55934E-06DCAF16-TRUEAluYSINE,Alu
chr1590375419TC0.00521C15orf38-AP3S2,AP3S2-TRUEAluJrSINE,Alu
chr1144594107CG0.00706NBPF20+FALSE
chr642047553AG0.00359TAF8+TRUEAluSz6SINE,Alu
chr1100440563AG0.00732SLC35A3+FALSEAluJbSINE,Alu
chr1675479484TC1.12347E-07TMEM170A-TRUEAluJbSINE,Alu
chr1148561089TC0.00975NBPF15+FALSE
chr193826611CG0.00072DR1+FALSE
chr2134728095AG8.47848E-05IFNAR1+TRUEAluScSINE,Alu
chr285773061AG0.00052GGCX-FALSE
chr1145273345TC0.00640NBPF20,NOTCH2NL+FALSE
chr1226333556CA0.00250ACBD3-FALSE(CAAAA)nSINE,Alu
chr1201845881AG0.00422IPO9+FALSE
chr744047381GA0.00912POLR2J4,SPDYE1+,-FALSE
chr4165998078TC0.00407TMEM192-TRUEAluSxSINE,Alu
chr117735300CA0.00128RCC2-FALSE
chr119542463TC0.00447LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr439550977TC3.35724E-05UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr811701429TC0.00496CTSB-TRUEAluSx1SINE,Alu
chr137958451CG0.00882MEAF6-FALSEMER5BSINE,Alu
chr72290522CT0.00517NUDT1+FALSE
chr1958375195AG0.00080ZNF587+TRUEAluSx4SINE,Alu
chr10104661031AG0.00265BORCS7-ASMT,AS3MT+TRUEAluYSINE,Alu
chr1145689717AG7.73781E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr729960315CT0.00015SCRN1-FALSE
chr119585493AG3.52757E-05MRTO4+TRUEAluSc8SINE,Alu
chr138326704TC0.00328INPP5B-TRUEAluJrSINE,Alu
chr116411935TC0.00905SMPD1+FALSE(CTGGCG)nSINE,Alu
chr1111489899CA0.00041LRIF1-FALSE
chr552388459AT0.00052ITGA2+FALSE
chrM10307AC0.00588.FALSE
chr2217366868AG0.00100.FALSEAluSz6SINE,Alu
chr3195243012AC0.00054PPP1R2-FALSE
chr1156005447CA0.00337UBQLN4-FALSE
chr1936260451AG0.00854.FALSEAluYSINE,Alu
chr126143725AT0.00988SEPN1+FALSEAluSxSINE,Alu
chr1155695968AG0.00017DAP3+TRUEAluSpSINE,Alu
chr1145282799GA0.00882NBPF20,NOTCH2NL+FALSE
chr8145159708AG0.00101MAF1+FALSE
chr1911256626TC1.61091E-07SPC24-TRUEAluJr4SINE,Alu
chr2110373919GA0.00669SOWAHC+FALSE
chr537290335TC1.49367E-06.FALSEAluSzSINE,Alu
chr1205687358TC0.00692NUCKS1-FALSE(T)nSINE,Alu
chr1109780743CA0.00643SARS+FALSE
chr133149266AG0.00292SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr5174956492AC0.00397SFXN1+FALSE
chr1152187183CA0.00373HRNR-FALSE
chr3183890097GA1.43668E-06DVL3+FALSE
chr133149414AG5.81443E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr153291425AG0.00034ZYG11B+TRUEAluJrSINE,Alu
chr119542456TC0.00193LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1120101744CA0.00540NAV2+FALSE
chr1167795299GA0.00764ALDH3B1+FALSE
chr119984107GA0.00963MINOS1-NBL1,NBL1+FALSE
chr119586455AG0.00245MRTO4+TRUEAluSzSINE,Alu
chr1155695998AG0.00078DAP3+TRUEAluSpSINE,Alu
chr3141667690TC0.00018TFDP2-TRUEAluYSINE,Alu
chr5125961573AG0.00217PHAX+TRUEAluSz6SINE,Alu
chr510655842CT0.00024ANKRD33B+FALSE
chr1179852074TC0.00309TOR1AIP1+FALSE
chr1773886219TC8.52474E-05TRIM65-TRUEFRAMSINE,Alu
chr136067817TC0.00016PSMB2-TRUEAluSzSINE,Alu
chr5175811091GA0.00592NOP16-FALSE
chr261764922GA0.00268XPO1-FALSE
chr568505909AG0.00178CENPH+TRUEAluSx3SINE,Alu
chr3179306775CT7.88487E-06MRPL47-FALSE
chr1205687341CT0.00494NUCKS1-FALSE(T)nSINE,Alu
chr310192826AG0.00037VHL+TRUEAluSx1SINE,Alu
chr168167217GT0.00036GNG12-FALSE
chr116934178CT0.00382NBPF1-FALSE
chr16730782CT0.00807DNAJC11-FALSE
chr552251222GT0.00808.FALSE(GATA)nSINE,Alu
chr1155032752AG0.00347LOC100505666,ADAM15+,-FALSE
chr2153506056TC0.00252FMNL2+FALSE
chr1772206017TA6.66319E-05RPL38+FALSE
chr119543353TC0.00077LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr128564252AG0.00118ATPIF1+FALSE
chr164097432CT0.00157PGM1+FALSE
chr2174828621AC0.00315SP3-FALSE
chrX54587290AG0.00504GNL3L+TRUEAluSq2SINE,Alu
chr340577745AG0.00044ZNF621+TRUEAluSzSINE,Alu
chr116889414TC0.00384NBPF1-TRUEL1MC4SINE,Alu
chr19910357AT0.00056CTNNBIP1-FALSE

Differential Expression Gene Analysis