Dataset Overview
RBP
SERBP1
Knock-Method
shRNA
RBP Family
HABP4_PAI-RBP1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR820ROH
Platform
HiSeq
Pubmed ID
32252787
SERBP1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of SERBP1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
8.64
14.82
0.92512
2.20661E-09
2.31781E-08
A1CF
29.82
23.06
0.22423
0.01809
0.04111
A2M
1827.0
3335.14
0.71737
5.69229E-18
1.77129E-16
AACS
14.57
9.04
-0.47895
1.24303E-05
6.43155E-05
AADAC
0.56
1.52
1.64414
1.23399E-06
7.83795E-06
AAED1
5.35
3.64
-0.48180
0.00317
0.00913
AAK1
3.2
5.57
0.93956
5.22436E-09
5.06614E-08
AAMP
132.44
103.12
-0.42973
3.15017E-06
1.86506E-05
AAR2
20.83
15.54
-0.22954
0.02880
0.06067
AARS
50.74
33.37
-0.42082
8.10323E-05
0.00035
Showing 1 to 10 of 6,889 entries
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Function Analysis of Target Genes of SERBP1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACLY
40052872_40052902_40049285_40049427_40054001_40054092
0.00518
-0.11
DataSet_01_54
View details
ACOT9
23752457_23752484_23751288_23751334_23754035_23754133
0.00713
0.26
DataSet_01_54
View details
ADRM1
60879516_60879633_60878623_60878837_60881252_60881376
0.00048
-0.077
DataSet_01_54
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AFP
74313330_74313393_74309063_74309161_74315051_74315184
0.00000
0.033
DataSet_01_54
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AFP
74313178_74313393_74309063_74309161_74315051_74315184
0.00000
0.018
DataSet_01_54
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AFP
74310709_74310839_74309067_74309161_74315051_74315184
0.00000
0.017
DataSet_01_54
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AFP
74320952_74321007_74319549_74319614_74321347_74321891
0.00005
-0.008
DataSet_01_54
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AGAP1
236839408_236839567_236817381_236817550_236877105_236877267
0.00969
-0.077
DataSet_01_54
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AHSA2
61410681_61410797_61408472_61408540_61411846_61411935
0.00593
0.066
DataSet_01_54
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AHSG
186336079_186336284_186334975_186335139_186337645_186337729
0.00566
0.117
DataSet_01_54
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Showing 1 to 10 of 221 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52603747_52603882_52619601_52619745_52601621_52601752
0.00043
0.195
DataSet_01_54
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ACADVL
7126451_7126556_7126962_7127049_7126078_7126184
0.00001
-0.079
DataSet_01_54
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ACADVL
7126962_7127049_7127131_7127194_7126451_7126556
0.00162
-0.108
DataSet_01_54
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ACSL3
223791734_223791907_223793579_223793654_223789173_223789313
0.00694
-0.045
DataSet_01_54
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ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00162
0.032
DataSet_01_54
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ADD1
2877622_2877837_2883624_2883787_2845583_2845751
0.00016
0.198
DataSet_01_54
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AFP
74310709_74310839_74313330_74313393_74309063_74309161
0.00166
-0.08
DataSet_01_54
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AHSG
186336300_186336426_186337645_186337729_186334975_186335139
0.00002
-0.009
DataSet_01_54
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AHSG
186334975_186335139_186337645_186337729_186334231_186334316
0.00257
-0.058
DataSet_01_54
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ANKRD11
89358088_89358185_89371613_89371752_89357420_89357591
0.00713
-0.113
DataSet_01_54
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Showing 1 to 10 of 139 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABHD3
19243638_19244191_19244078_19244191_19239130_19239304
0.00932
-0.055
DataSet_01_54
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AHSG
186336079_186336284_186336079_186336280_186337645_186337729
0.00639
0.394
DataSet_01_54
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AKR1A1
46032540_46032758_46032540_46032692_46033653_46033849
0.00259
0.142
DataSet_01_54
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ALB
74279136_74279307_74279136_74279299_74280751_74280884
0.00000
-0.013
DataSet_01_54
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ARHGEF40
21555159_21555622_21555159_21555264_21556126_21556257
0.00769
0.115
DataSet_01_54
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ATXN2L
28847253_28847806_28847253_28847443_28848048_28848558
0.00093
-0.175
DataSet_01_54
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CALD1
134617738_134618828_134617738_134618141_134625842_134625988
0.00919
0.039
DataSet_01_54
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ENY2
110346552_110346703_110346552_110346631_110348356_110348433
0.00929
-0.058
DataSet_01_54
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FKBP10
39975781_39976301_39975781_39975927_39976520_39976713
0.00326
0.068
DataSet_01_54
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GRHPR
37422710_37422830_37422710_37422802_37424841_37424972
0.00291
-0.181
DataSet_01_54
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Showing 1 to 10 of 21 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AP1G2
24031170_24031394_24031170_24031275_24031496_24031624
0.00170
0.106
DataSet_01_54
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AP1G2
24031170_24031316_24031170_24031275_24031496_24031624
0.00499
0.104
DataSet_01_54
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ATP6V1G2-DDX39B
31508258_31508343_31508258_31508311_31509726_31509925
0.00040
-0.205
DataSet_01_54
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CLINT1
157216370_157216575_157216370_157216521_157218710_157219003
0.00462
-0.121
DataSet_01_54
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CPSF1
145622701_145622876_145622701_145622868_145622957_145623094
0.00790
-0.08
DataSet_01_54
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CSF1
110465787_110466812_110466681_110466812_110464468_110464616
0.00046
0.126
DataSet_01_54
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FLOT1
30708966_30709481_30708966_30709110_30709568_30709644
0.00839
-0.13
DataSet_01_54
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FN1
216236631_216237098_216236631_216236738_216238044_216238134
0.00181
-0.006
DataSet_01_54
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HERC2P2
23282280_23283416_23282280_23283153_23285704_23285752
0.00393
0.099
DataSet_01_54
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HNRNPC
21731469_21731988_21731469_21731495_21737456_21737601
0.00003
0.144
DataSet_01_54
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Showing 1 to 10 of 26 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00526
0.065
DataSet_01_54
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ABCF3
183905184_183905549_183905184_183905231_183905451_183905549
0.00111
0.162
DataSet_01_54
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AC002116.8
36501468_36501979_36501468_36501585_36501795_36501979
0.00268
0.202
DataSet_01_54
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ADCK4
41211000_41211352_41211000_41211086_41211229_41211352
0.00395
0.337
DataSet_01_54
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ANO9
418719_418989_418719_418813_418887_418989
0.00837
0.136
DataSet_01_54
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AP1G2
24031170_24031624_24031170_24031275_24031496_24031624
0.00014
0.135
DataSet_01_54
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APEX1
20923736_20924260_20923736_20923862_20924072_20924260
0.00332
0.045
DataSet_01_54
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ATXN2L
28847253_28848558_28847253_28847806_28848048_28848558
0.00765
0.076
DataSet_01_54
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CLCN7
1499276_1500667_1499276_1499328_1500497_1500667
0.00050
-0.14
DataSet_01_54
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CYP3A5
99260438_99261718_99260438_99260505_99261590_99261718
0.00880
-0.193
DataSet_01_54
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
35223881
G
A
0.00228
GJB5
+
FALSE
chr1
20238572
A
T
0.00950
OTUD3
+
FALSE
chr1
109535117
C
T
0.00211
WDR47
-
FALSE
chr1
94342564
C
A
0.00098
DNTTIP2
-
FALSE
chr1
143189042
C
T
0.00087
LOC102723769
-
FALSE
L1MC4
SINE,Alu
chr1
10517273
T
C
0.00583
.
FALSE
AluJr
SINE,Alu
chr1
25168124
G
C
0.00669
CLIC4
+
FALSE
chr1
76253041
T
A
0.00646
RABGGTB
+
FALSE
chr1
6282301
T
C
0.00290
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
100489992
A
G
0.00938
SLC35A3
+
TRUE
AluSg
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression