Dataset Overview
RBPLSM11
Knock-MethodshRNA
RBP FamilyLSM
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR762FEO
PlatformHiSeq
Pubmed ID32252787

LSM11 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of LSM11
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of LSM11


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr110520588TC0.00341.FALSEAluSc8SINE,Alu
chr6143382534CT0.00252AIG1+FALSE
chrX77084017TC0.00179MAGT1-TRUEAluSzSINE,Alu
chr9115446659TC0.00410INIP-TRUEAluJrSINE,Alu
chr162673225GA0.00039L1TD1+FALSEL1MEdSINE,Alu
chr16283296TC0.00106ICMT-TRUEAluSx3SINE,Alu
chr1150969257TC0.00400.FALSEAluSq2SINE,Alu
chr261416411TG0.00146USP34-FALSEAluSc8SINE,Alu
chr1163288931GA0.00284RGS5-FALSEMamRep1527SINE,Alu
chr6150045926TC0.00053NUP43-TRUEAluSqSINE,Alu
chr120977380TC0.00695PINK1,PINK1-AS+,-FALSE
chr171532815GA0.00712ZRANB2-AS1,ZRANB2+,-FALSE
chr119543456TC0.00386LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr126774225AG0.00614DHDDS+TRUEAluSz6SINE,Alu
chr1244182706AG0.00788IRAK4+FALSEMSTB-intSINE,Alu
chr9124095000TG0.00764GSN+FALSE(TG)nSINE,Alu
chr168940566AC0.00126DEPDC1-FALSE
chr9125866693CT0.00255RABGAP1+FALSE
chr727237453CT0.00421HOXA13-FALSE
chr1173457945GA0.00287PRDX6+FALSE
chr1186370281CG0.00387C1orf27,OCLM+FALSE
chr842043493GA0.00045PLAT-FALSEMLT2C1SINE,Alu
chr19642827GA0.00521SLC25A33+FALSE
chr116946266GC0.00750CROCCP2-FALSEMIRbSINE,Alu
chr3105271344AG0.00460ALCAM+FALSE
chr110518826TC0.00292.FALSEAluSx1SINE,Alu
chr398516118TA0.00541DCBLD2-FALSE
chr1161929879AT0.00680ATF6+FALSE
chr631323203AG2.54151E-09.FALSE
chr132661578CT0.00694TXLNA+FALSE(T)nSINE,Alu
chr477996987TC0.00240CCNI-FALSE
chr117345246AT0.00812SDHB-FALSE
chr140219065CT0.00232PPIE+FALSE
chr19161137TC0.00087.FALSEAluSxSINE,Alu
chr425236017TC2.76644E-09PI4K2B+FALSE
chr192862826AG0.00100.FALSEAluJrSINE,Alu
chr1765335253TC0.00344PSMD12-TRUEAluSxSINE,Alu
chr1729578724CT0.00514NF1+FALSE
chr2134728099AG1.57787E-05IFNAR1+TRUEAluScSINE,Alu
chr5130537747AG1.40133E-05LYRM7+TRUEAluJbSINE,Alu
chr1145512024AG0.00247NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1688789703CG0.00498PIEZO1-FALSE
chr116576836AG0.00885FBXO42-FALSE
chr110517688TC0.00020.FALSEAluSx1SINE,Alu
chr830536146TC1.15312E-06GSR-TRUEAluJrSINE,Alu
chr417802783TC6.83941E-07DCAF16-TRUEAluSzSINE,Alu
chr1326539AG0.00719.FALSE
chr632800221CT0.00900.FALSE(GCATCA)nSINE,Alu
chr4248840AG0.00655ZNF876P+TRUEAluYk3SINE,Alu
chr3191111160AG4.43846E-07CCDC50+FALSE
chr1666923452AG0.00065PDP2+TRUEAluSzSINE,Alu
chr121793735CG0.00405NBPF3+FALSE
chr7149318375CT0.00383ZNF767P-FALSE
chr1197070776CT0.00698ASPM-FALSE
chr6160526904TG0.00027IGF2R+FALSE
chr674303531TC0.00487SLC17A5-TRUEAluJrSINE,Alu
chr9133778117CT0.00739FIBCD1-FALSE
chr1100615003GA0.00046TRMT13,LRRC39+,-FALSE
chr197144886AG0.00078.FALSE
chr12115914GT0.00970PRKCZ,FAAP20+,-FALSE
chr119953124GA0.00137MINOS1,MINOS1-NBL1+FALSE
chr1118502087CT0.00585WDR3,SPAG17+,-FALSE
chr6138412313AG0.00092PERP-FALSE
chr340503561AT0.00012RPL14+FALSE
chr19162348TC0.00359.FALSEAluSxSINE,Alu
chr1749041897TC4.67707E-06SPAG9-TRUEAluSxSINE,Alu
chr116892913AG0.00441NBPF1-FALSE
chr624719404CA0.00024.FALSE
chr16283264TC0.00479ICMT-TRUEAluSx3SINE,Alu
chr3156259348GA0.00899SSR3-FALSEAluSq2SINE,Alu
chr19324213CT0.00063H6PD+FALSE
chr438945834TC0.00287FAM114A1+FALSEAluScSINE,Alu
chr1145688943AG0.00492NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr154691921GA0.00909SSBP3-FALSE
chr116913677TC0.00638NBPF1-FALSE
chr110520383TC0.00401.FALSEAluSx1SINE,Alu
chr132799437CT0.00318MARCKSL1-FALSE
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr1144828765AT0.00976NBPF20,NBPF9+FALSE
chr12125514122AG1.22592E-05.FALSE(TA)nSINE,Alu
chrX3523048AT0.00055PRKX-FALSE
chr1013320123CA0.00830PHYH-FALSE
chr1109818158CT0.00628CELSR2+FALSE
chr13545192CG0.00332TPRG1L+FALSE
chr1143135166GT0.00325LOC102723769-FALSE
chr340577745AG0.00044ZNF621+TRUEAluSzSINE,Alu
chr1269237509AG1.55617E-05MDM2+TRUE
chr581571876AT0.00013RPS23-FALSE
chr2197004439AG0.00034STK17B-FALSE
chr1051374391CG0.00028TIMM23B+FALSE
chr2203745105TC0.00644.FALSEAluSxSINE,Alu
chr2171699153CG0.00247GAD1+FALSE
chr1145688665TA0.00015NBPF20,NBPF10,RNF115+FALSE
chr141236854TA0.00075NFYC+FALSE(T)nSINE,Alu
chr193308173TG0.00380FAM69A-FALSE
chr127426756AG0.00384SLC9A1-FALSE
chr126801731GT0.00325HMGN2+FALSE(T)nSINE,Alu
chr642856156AG0.00105RPL7L1+TRUEAluSzSINE,Alu
chr224225013AG0.00103.FALSEAluSxSINE,Alu
chr1541590288GT0.00349OIP5-AS1+FALSE
chr3196044972CT0.00258TCTEX1D2,TM4SF19-TCTEX1D2-FALSE
chr1115119377AT0.00157BCAS2-FALSE
chr1119245854TC0.00078E2F8-FALSE
chr110517290TC0.00060.FALSEAluJrSINE,Alu
chr765844562TC0.00695LINC00174-FALSE
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr417803009TC0.00062DCAF16-TRUEAluSzSINE,Alu
chr126131654GA0.00149SEPN1+FALSE
chr274334790AG0.00870TET3+FALSE
chr564964627TC0.00998SGTB-TRUEAluSx1SINE,Alu
chr124786GA0.00285WASH7P-FALSE
chr1450361170CT0.00096ARF6+FALSE(T)nSINE,Alu
chr633648144CT0.00453ITPR3+FALSE
chr5139931633CA0.00014SRA1-FALSE
chr310285030GA0.00384IRAK2+FALSE
chr2204312707CT0.00154RAPH1-FALSE
chr1118069696TC0.00922.FALSE
chr1206566195CT0.00052SRGAP2+FALSE
chr110518591AT0.00169.FALSE
chr167895926AG0.00705SERBP1-FALSE
chr1658054472TC0.00530USB1+FALSE
chr3192515510GT0.00559MB21D2-FALSE
chr10120920588TC0.00304SFXN4-FALSE
chr1202697335GA0.00374KDM5B-FALSE
chr1542503336CT0.00916TMEM87A-FALSE(T)nSINE,Alu
chr348787757TC0.00605PRKAR2A-TRUEAluSpSINE,Alu
chr2239259541AG0.00134CBX6-FALSE
chr285824712CA0.00663RNF181+FALSE
chr13545189TG0.00027TPRG1L+FALSE
chr116889127AG0.00213NBPF1-FALSEL1MC4SINE,Alu
chr2135208352TG0.00259MGAT5+FALSE
chr275882576TC0.00328MRPL19+FALSE
chr9139100154CG0.00464QSOX2-FALSE
chr11325721CT0.00471CCNL2-FALSE
chr1161088583TG0.00822NIT1+FALSE
chr579923793TC0.00664DHFR-TRUEAluSpSINE,Alu
chr16282361TC0.00634ICMT-TRUEAluSzSINE,Alu
chr182804129GA0.00157SMCHD1+FALSE
chr358292297TC0.00950RPP14+FALSE
chr111979809AC0.00836KIAA2013-FALSE
chr11595586TC0.00206CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr3121351277AT0.00388HCLS1-FALSE
chr344791355TC0.00468KIAA1143-TRUEAluJrSINE,Alu
chr76501829TA0.00081KDELR2-FALSE
chr197085418AG6.02730E-06ZNF557+TRUEAluJbSINE,Alu
chr228002603CA0.00010MRPL33+FALSE
chr116841620TA0.00023.FALSE
chr190496713AG0.00677ZNF326+FALSE
chr132374019GA0.00297PTP4A2-FALSE
chr349395692GA0.00049GPX1-FALSE(GCC)nSINE,Alu
chr632796463AC0.00680.FALSE(CCCCA)nSINE,Alu
chrX16781186AG0.00220.FALSEAluJoSINE,Alu
chr153289860AG0.00346ZYG11B+TRUEFRAMSINE,Alu
chr232535747AG0.00250.FALSEAluJbSINE,Alu
chr111084345CT0.00558TARDBP+FALSE
chr2232319583CA0.00801NCL-FALSEA-richSINE,Alu
chr1212273639CT0.00710DTL+FALSE
chr2136541076CA0.00211UBXN4+FALSE
chr10126677249AT0.00762CTBP2-FALSE
chr1154557171GA0.00045ADAR-FALSEA-richSINE,Alu
chr1161931167AG0.00251ATF6+FALSE
chr1120162787TC0.00925ZNF697-FALSE
chr1211921422TG0.00686LPGAT1-FALSE
chr237328034TC8.99638E-05.FALSE
chr11653046TA0.00686CDK11B,CDK11A-FALSE
chr128835937AG0.00121SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1145689566AG0.00331NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr2043996145TA0.00611SYS1-DBNDD2,SYS1+FALSE
chr124935369AG0.00454NCMAP+TRUEAluJbSINE,Alu
chr16659505GA0.00405KLHL21-FALSE
chr2220370192CT0.00055GMPPA+FALSE
chr2130900880CT0.00044CCDC74B-FALSE
chr4128758175AG0.00385.FALSEAluSxSINE,Alu
chr1089623858GC0.00086PTEN+FALSE(CGG)nSINE,Alu
chr261705068AT0.00103.FALSE
chr126802401TG4.43852E-05HMGN2+FALSE
chr153290298AG0.00063ZYG11B+TRUEAluSg4SINE,Alu
chr152306079TA0.00606NRDC-FALSE(TCA)nSINE,Alu
chr1269237056AG0.00372MDM2+TRUE
chr6111588769AG2.24603E-05MFSD4B+TRUEAluYm1SINE,Alu
chr5170832637CT0.00071NPM1+FALSE
chr8128944720GT0.00751PVT1+FALSE
chr755433884AC0.00723LANCL2+FALSE
chr110518688TC0.00154.FALSEAluSx1SINE,Alu
chr1145283980CT0.00113NBPF20,NOTCH2NL+FALSE
chr1100658578GA5.62742E-07DBT-FALSE
chr1113240711GA0.00454MOV10+FALSE
chr634231301GC0.00772.FALSE
chr247562582GA0.00484LOC101927043-FALSEBC200SINE,Alu
chr5125961554AG0.00355PHAX+TRUEAluSz6SINE,Alu
chr165330637CT0.00251JAK1-FALSE
chr153288916AG0.00289ZYG11B+TRUEAluJoSINE,Alu
chr1680636808CT0.00881CDYL2-FALSE
chr342610515GA0.00099SEC22C-FALSE
chr353268235AC0.00452TKT-FALSE
chr565453894TA0.00211SREK1+FALSE
chr356703746AC0.00017FAM208A-FALSE
chr138326643TC0.00458INPP5B-TRUEAluJrSINE,Alu
chr211053740CT0.00402KCNF1+FALSE
chr1214529170TC0.00120PTPN14-TRUE
chr153680205CT4.54902E-05C1orf123-FALSE
chr1197070442GT0.00468ASPM-FALSE
chr1148556784GA0.00543.FALSE
chr133148196AG0.00303SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr764441627GA0.00478ZNF117-FALSE
chr537290336TC0.00036.FALSEAluSzSINE,Alu
chr7154796171GA0.00066PAXIP1-AS1+FALSEAluSx3SINE,Alu
chr1179045500CA0.00043FAM20B+FALSE
chr238971059AC0.00539SRSF7-FALSE
chr1201846618CA0.00404IPO9+FALSE(CA)nSINE,Alu
chr111347155CT0.00366UBIAD1+FALSE
chr310005650CT0.00698EMC3-FALSE
chr120977599CG0.00489PINK1,PINK1-AS+,-FALSE
chr1183515428GA0.00232SMG7+FALSE
chr3156258319TC0.00012SSR3-TRUEAluYk3SINE,Alu
chr18412989AG0.00225RERE-FALSE
chr613790964TC5.10728E-05MCUR1-TRUEAluSx1SINE,Alu
chr2158170017TC0.00662GALNT5+FALSE
chr273480136TA0.00281CCT7+FALSE
chr1145369709AG0.00607NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr120976163CT0.00091PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr2239973454TC0.00091HDAC4-FALSE
chrX77083939TC5.71267E-05MAGT1-TRUEAluSzSINE,Alu
chr1117945049GA0.00120MAN1A2+FALSE
chr152306087CT0.00022NRDC-FALSE(TCA)nSINE,Alu
chr110520154TC0.00021.FALSEAluSxSINE,Alu
chr1075009720TC0.00016DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr540832549CT2.26031E-05RPL37-FALSE
chr1331033325CA0.00792HMGB1-FALSE
chr1589803950CT0.00698FANCI+FALSE
chr345126558CT0.00000CDCP1-FALSE
chr1153507176CT0.00957S100A6-FALSE
chr1180082720GA0.00577CEP350+FALSE
chr1212277616CT0.00248DTL+FALSE
chr1149943157GA0.00024OTUD7B-FALSE
chr233623905GT0.00262LTBP1+FALSE
chr345722491AG0.00734LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr167874696TC0.00012SERBP1-TRUEAluSx3SINE,Alu
chr128825465AG0.00756PHACTR4+TRUEAluSgSINE,Alu
chr5178986978CG0.00341RUFY1+FALSE
chr170718278CG0.00663.FALSE
chr12133298938AG0.00034PGAM5+TRUEAluSgSINE,Alu
chr1946053667AG0.00995OPA3-FALSE
chr1419684445AG0.00351DUXAP10+FALSE
chr110520117TC0.00999.FALSEAluSxSINE,Alu
chr348787118TC0.00359PRKAR2A-TRUEAluSx3SINE,Alu
chr128826085AG0.00212PHACTR4+TRUEAluJbSINE,Alu
chr388104168CT0.00919CGGBP1-FALSE
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr1921131571AG0.00120ZNF85+FALSE
chr1571124666CA4.50846E-10LARP6-FALSE
chr1201845881AC0.00032IPO9+FALSE
chr74810530GA0.00236FOXK1+FALSE(GT)nSINE,Alu
chr112677525GA0.00122DHRS3-FALSE(A)nSINE,Alu
chr119542250TC0.00780LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr138327586CT0.00198INPP5B-FALSEAluSx3SINE,Alu
chr16662500CG0.00235KLHL21-FALSE
chr1900717CT0.00661KLHL17+FALSE(TTTA)nSINE,Alu
chr1773886212TC0.00724TRIM65-TRUEFRAMSINE,Alu
chr12241376CT0.01000SKI+FALSE
chr314986461TC3.09385E-06FGD5-AS1-TRUEAluSq2SINE,Alu
chr728860031AT0.00017CREB5+FALSE
chr3197612430AG0.00052.FALSEAluSpSINE,Alu
chr2241825926TC7.75373E-05C2orf54-FALSE
chr141204569CT0.00854NFYC+FALSE
chr1225156655CT0.00671DNAH14+FALSE
chr145975584TC0.00327MMACHC+FALSEAluSx4SINE,Alu
chr1120839680AC0.00584FAM72B+FALSE
chr126608017TA3.67009E-06.FALSE
chr187379497AG0.00067SEP15-FALSE
chr315094061GA0.00188MRPS25-FALSE
chr642855101AG0.00329RPL7L1+TRUEAluSpSINE,Alu
chr185715978CG0.00815C1orf52-FALSE
chr146164493TC0.00325IPP-TRUEAluJbSINE,Alu

Differential Expression Gene Analysis